• Title/Summary/Keyword: geometrical diasteromers

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The absolute configuration of ketoprofen

  • Kim, Jin-Woong;Jew, Sang-Sup;Cho, Youn-Sang;Cook, Chae-Ho
    • Archives of Pharmacal Research
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    • v.10 no.1
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    • pp.25-28
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    • 1987
  • (+)-Ketoprofen was obtained form resolution with (S) (+)-2-amino-1-butanol and its absolute configuration was determined to be (S) by chemical correlation with (S) (+)-ethyl hydratropate using Beckmann rearrangement as a key step.

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