• Industrial Engineering and Management Systems
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• v.3 no.2
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• pp.123-128
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• 2004

A tree structure model has been proposed for representing the unequal-area facility layout. Each facility has a different rectangular shape specified by its area and aspect ratio. In this layout problem, based on the assumption that the shop floor has enough space for laying out the facilities, no constraint is considered for a shop floor. Objectives are minimizing total part movement between facilities and total rectangular layout area where all facilities and dead spaces are enclosed. Using the genetic code corresponding to two kinds of information, facility sequence and branching positions in the tree structure model, a genetic algorithm has been applied for finding non-dominated solutions in the two-objective layout problem. We use three kinds of crossover (PMX, OX, CX) for the former part of the chromosome and one-point crossover for the latter part. Two kinds of layout problems have been tested by the proposed method. The results demonstrate that the presented algorithm is able to find good solutions in enough short time.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2001.10a
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• pp.231-236
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• 2001

The goal of multiphase optimization of machine structure is to obtain 1) light weight, 2) statically and dynamically rigid structure. The entire optimization process is carried out in two phases. In the first phase, multiple optimization problem with two objective functions is treated using pareto genetic algorithm. Two objective functions are weight of the structure, and static compliance. In the second phase, maximum receptance is minimized using genetic algorithm. The method is applied to design of quill type machine structure with back column.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.1
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• pp.1-14
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• 2021

Cardiovascular disease (CVD) accounts for approximately 30% of all deaths worldwide and its prevalence is constantly increasing despite advancements in medical treatments. Cardiac remodeling and dysfunction are independent risk factors for CVD. Recent studies have demonstrated that cardiac structure and function are genetically influenced, suggesting that understanding the genetic basis for cardiac structure and function could provide new insights into developing novel therapeutic targets for CVD. Regular exercise has long been considered a robust nontherapeutic method of treating or preventing CVD. However, recent studies also indicate that there is inter-individual variation in response to exercise. Nevertheless, the genetic basis for cardiac structure and function as well as their responses to exercise training have yet to be fully elucidated. Therefore, this review summarizes accumulated evidence supporting the genetic contribution to these traits, including findings from population-based studies and unbiased large genomic-scale studies in humans.

• Mycobiology
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• v.49 no.4
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• pp.376-384
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• 2021

Agaricus bisporus is a popular edible mushroom that is cultivated worldwide. Due to its secondary homothallic nature, cultivated A. bisporus strains have low genetic diversity, and breeding novel strains is challenging. The aim of this study was to investigate the genetic diversity and population structure of globally collected A. bisporus strains using simple sequence repeat (SSR) markers. Agaricus bisporus strains were divided based on genetic distance-based groups and model-based subpopulations. The major allele frequency (MAF), number of genotypes (NG), number of alleles (NA), observed heterozygosity (HO), expected heterozygosity (HE), and polymorphic information content (PIC) were calculated, and genetic distance, population structure, genetic differentiation, and Hardy-Weinberg equilibrium (HWE) were assessed. Strains were divided into two groups by distance-based analysis and into three subpopulations by model-based analysis. Strains in subpopulations POP A and POP B were included in Group I, and strains in subpopulation POP C were included in Group II. Genetic differentiation between strains was 99%. Marker AB-gSSR-1057 in Group II and subpopulation POP C was confirmed to be in HWE. These results will enhance A. bisporus breeding programs and support the protection of genetic resources.

• Korean Journal of Computational Design and Engineering
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• v.19 no.1
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• pp.1-11
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• 2014

In the initial design stage, the technology for estimating and managing the weight of a floating offshore structure, such as a FPSO (Floating, Production, Storage, and Off-loading unit) and an offshore wind turbine, has a close relationship with the basic performance and the price of the structure. In this study, using the genetic programming (GP), being used a lot in the approximate estimating model and etc., the weight estimation model of the floating offshore structure was studied. For this purpose, various data for estimating the weight of the floating offshore structure were collected through the literature survey, and then the genetic programming method for developing the weight estimation model was studied and implemented. Finally, to examine the applicability of the developed model, it was applied to examples of the weight estimation of a FPSO topsides and an offshore wind turbine. As a result, it was shown that the developed model can be applied the weight estimation process of the floating offshore structure at the early design stage.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.1177-1180
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• 1996

In this paper, we propose an algorithm that realizes cooperative behavior by construction of autonomous mobile robot system. Each robot is able to sense other robots and obstacles, and it has the rule of behavior to achieve the goal of the system. In this paper, to improve performance of the whole system, we use Genetic Programming based on Natural Selection. Genetic Programming's chromosome is a program of tree structure and it's major operators are crossover and mutation. We verify the effectiveness of the proposed scheme from the several examples.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2000.05a
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• pp.1027-1031
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• 2000

In this paper, multiphase dynamic optimization of machine structure is presented. The final goal is to obtain ( i ) light weight, and ( ii ) rigidity statically and dynamically. The entire optimization process is carried out in two steps. In the first step, multiple optimization problem with two objective functions is treated using Pareto genetic algorithm. Two objective functions are weight of the structure, and static compliance. In the second step, maximum receptance is minimized using genetic algorithm. The method is applied to a simplified milling machine.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2003.05a
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• pp.279-280
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• 2003

Although it has been known though many morphological and physiological studies, its genetic diversity and population structure have not yet been investigated in this species. Therefore, detailed studies, in particular at the DNA level, on genetic diversity of natural populations of wild sea lettuce, and genetic relationships between natural sea lettuce and cultivated sea lettuce are necessary from the viewpoint of plant evolution. (omitted)

• Journal of Educational Research in Mathematics
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• v.12 no.3
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• pp.409-424
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• 2002

The historico-genetic principle has been advocated continuously, as an alternative one to the traditional deductive method of teaching and learning mathematics, by Clairaut, Cajori, Smith, Klein, Poincar$\'{e}$, La Cour, Branford, Toeplitz, etc. since 18C. And recently we could find various studies in relation to the historico-genetic principle. Lakatos', Freudenthal's, and Brousseau's are representative in them. But they are different from the previous historico- genetic principle in many aspects. In this study, the previous historico- genetic principle is called as classical historico- genetic principle and the other one as modern historico-genetic principle. This study shows that the differences between them arise from the historical views of mathematics and the development of the theories of mathematics education. Dewey thinks that education is a constant reconstruction of experience. This study shows the historico-genetic principle could us embody the Dewey's psycological method. Bruner's discipline-centered curriculum based on Piaget's genetic epistemology insists on teaching mathematics in the reverse order of historical genesis. This study shows the real understaning the structure of knowledge could not neglect the connection with histogenesis of them. This study shows the historico-genetic principle could help us realize Bruner's point of view on the teaching of the structure of mathematical knowledge. In this study, on the basis of the examination of the development of the historico-genetic principle, we try to stipulate the principle more clearly, and we also try to present teaching unit for the logarithm according to the historico- genetic principle.

• Korean Journal of Medicinal Crop Science
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• v.21 no.3
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• pp.220-228
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• 2013

This study was conducted to assess the genetic diversity and population structure of 70 amaranth accessions collected from South and Southeast Asia using 14 simple sequence repeat (SSR) markers. In total, 67 alleles were detected, with an average of 4.79 per locus. Rare alleles comprised a large portion (46.3%) of the detected alleles, and 29 unique alleles associated with rice accessions were also discovered. The mean major allele frequency (MAF), genetic diversity (GD) and polymorphic information content (PIC) of the 14 SSR loci were 0.77, 0.36, and 0.34, respectively. A model-based structural analysis revealed the presence of three subpopulations. The genetic relationships revealed by the neighbor-joining tree method were fairly consistent with the structure-based membership assignments for most of the accessions. All 70 accessions showed a clear relationship to each cluster without any admixtures. We observed a relatively low extent of genetic exchange within or among amaranth species from South and Southeast Asia. The genetic diversity results could be used to identify amaranth germplasms and so facilitate their use for crop improvement.