• 제어로봇시스템학회논문지
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• 제6권11호
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• pp.1013-1021
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• 2000

This paper suggests fuzzy-PI controllers for a heavy-duty gas turbine. The fuzzy-PI controllers are designed to regulate rotor speed and exhaust temperature of the gas turbine. The controller gains are tuned by genetic algorithm(GA). This paper also proposes a new fitness function of GA using a desired output response. The suggested controller is compared with previous controllers via simulations and it is shown that the rotor speed variation of our controller is smaller than those of previous ones.

• Asian-Australasian Journal of Animal Sciences
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• 제27권10호
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• pp.1387-1393
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• 2014

This study aimed to estimate genetic correlation between carcass grading and retail productivity traits and to estimate the correlated response on retail productivity traits through selection for carcass grading traits in order to assess the efficacy of indirect selection. Genetic parameters were estimated with the data from 4240 Hanwoo steers using mixed models, and phenotypes included carcass weight (CWT), back fat thickness (BFT), eye muscle area (EMA), marbling (MAR), and estimated lean yield percentage (ELP) as the carcass grading traits, and weight and portion of retail cuts (RCW and RCP), trimmed fats (TFW and TFP) and trimmed bones (TBW and TBP) as the lean productivity traits. The CWT had positive genetic correlations with RCW (0.95) and TFW (0.73), but its genetic correlation with RCP was negligible (0.02). The BFT was negatively correlated with RCP (-0.63), but positively correlated with TFW and TFP (0.77 and 0.70). Genetic correlations of MAR with TFW and TFP were low. Among the carcass grading traits, only EMA was positively correlated with both RCW (0.60) and RCP (0.72). The EMA had a relatively strong negative genetic correlation with TFW (-0.64). The genetic correlation coefficients of ELP with RCP, TFW, and TFP were 0.76, -0.90, and -0.82, respectively. These correlation coefficients suggested that the ELP and EMA might be favorable traits in regulating lean productivity of carcass.

• Journal of Ginseng Research
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• 제34권4호
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• pp.296-303
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• 2010

A peroxiredoxin cDNA (PgPrx) was isolated and characterized from the leaves of Panax ginseng. The cDNA is 716 nucleotides long and has an open reading frame of 489 base pairs with a deduced amino acid sequence of 162 residues. The calculated molecular mass of the mature protein is approximately 17.4 kDa with a predicted isoelectric point of 5.37. A GenBank BlastX search revealed that the deduced amino acid sequence of PgPrx shares a high degree homology with type II peroxiredoxin (Prx) proteins in other plants. The PgPrx gene was highly expressed in leaves, and expressed at a low level in the stem. To analyze the gene expression of PgPrx in response to various abiotic stresses, we utilized real-time quantitative RT-PCR. Our results reveal that PgPrx expression is induced by ultraviolet irradiation, low temperature, and salt. The induction of PgPrx in response to abiotic stimuli suggests that ginseng Prx may function to protect the host against environmental stresses.

• BMB Reports
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• 제35권4호
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• pp.409-413
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• 2002

Thioltransferase, also known as glutaredoxin, is an enzyme that catalyzes the reduction of a variety of disulfide compounds. In Schizosaccharomyces pombe, two thioltransferases were reported and the cDNA of one of the thioltransferases (thioltransferase-1) was cloned. Using a Northern blot assay, we investigated the thioltransferase transcription in response to various stress conditions. When the culture was shifted to a high temperature, the thioltransferases transcription was not significantly changed compared to the unshifted $30^{\circ}C$ culture. Treatment of zinc chloride to exponentially-growing cells remarkably increased the thioltransferase transcription, whereas the treatment of mercury chloride greatly reduced the transcription. Treatment of hydrogen peroxide and cadmium chloride caused no significant effects on the transcription of the thioltransferase. These results suggest that the transcription of thioltransferase-1 in S. pombe is induced in response to metal stress that is caused by zinc chloride, but not in response to heat stress or oxidative stress that is caused by hydrogen peroxide.

• Journal of Mechanical Science and Technology
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• 제18권10호
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• pp.1829-1836
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• 2004

This study presents the performance optimization of hypervelocity launcher system by using the experimentall data. During the optimization, the RSM (Response Surface Method) is adopted to find the operating parameters that could maximize the projectile speed. To construct a reliable response surface model, 3 full factorial method is used with the selected design variables, such as piston mass and 2 driver fill pressure. Nine test data could successfully construct the reasonable response surface, which used to yield the optimal operational conditions of the system using the genetic algorithm. The optimization results are confirmed by the experimental test with a good accuracy. Thus, the optimization can improve the performance of the facility.

• Molecules and Cells
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• 제26권4호
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• pp.350-355
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• 2008

Chk2 is a well characterized protein kinase with key roles in the DNA damage response. Chk2 is activated by phosphorylation following DNA damage, and relays that signal to various substrate proteins to induce cell cycle arrest, DNA repair, and apoptosis. In order to identify novel components of the Chk2 signaling pathway in Drosophila, we screened 2,240 EP misexpression lines for dominant modifiers of an adult rough eye phenotype caused by Chk2 overexpression in postmitotic cells of the eye imaginal disc. The rough eye phenotype was suppressed by mutation of the ATM kinase, a well-described activator of Chk2. Twenty-five EP modifiers were identified (three enhancers and 22 suppressors), none of which correspond to previously known components of Chk2 signaling. Three EPs caused defects in G2 arrest after irradiation with incomplete penetrance when homozygous, and are likely directly involved in the response to DNA damage. Possible roles for these modifiers in the DNA damage response and Chk2 signaling are discussed.

• 소음진동
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• 제11권1호
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• pp.147-155
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• 2001

This paper is concerned with the real-time automatic tuning of the multi-input multi-output positive position feedback controllers for smart structures by the genetic algorithms. The genetic algorithms have proven its effectiveness in searching optimal design parameters without falling into local minimums thus rendering globally optimal solutions. The previous real-time algorithm that tunes a single control parameter is extended to tune more parameters of the MIMO PPF controller. We employ the MIMO PPF controller since it can enhance the damping value of a target mode without affecting other modes if tuned properly. Hence, the traditional positive position feedback controller can be used in adaptive fashion in real time. The final form of the MIMO PPF controller results in the centralized control, thus it involves many parameters. The bounds of the control Parameters are estimated from the theoretical model to guarantee the stability. As in the previous research, the digital MIMO PPF control law is downloaded to the DSP chip and a main program, which runs genetic algorithms in real time, updates the parameters of the controller in real time. The experimental frequency response results show that the MIMO PPF controller tuned by GA gives better performance than the theoretically designed PPF. The time response also shows that the GA tuned MIMO PPF controller can suppress vibrations very well.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.1006-1011
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• 2003

In this study, a novel systematic design procedure by Genetic Algorithm of a two stage relief valve is proposed. First of all, a mathematical model describing the dynamics of a balanced piston type relief valve has been derived. Governing equations such as dynamic equations for the main spool and the pilot spool and flow equations for each orifice are established. The mathematical model is verified by comparing the results of simulation with that of experiments. Furthermore, influences of the parameters on the dynamic characteristics of a relief valve have been investigated by simulation of the proposed model. Major design parameters on the valve response are determined, which affect the system response significantly. And then, using the determined parameters, the optimization of the two stage relief valve by Genetic Algorithm, which is a random search algorithm can find the global optimum without converging local optimum, is performed. The optimal design process of a two stage relief valve is presented to determine the major design parameters. Fitness function reflects the changing pressure according to parameters. It is shown that the genetic algorithms satisfactorily optimized the major design parameters of the two stage relief valve.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 추계학술대회 논문집
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• pp.501-506
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• 2002

In this study, a novel systematic design procedure by Genetic Algorithm of a two stage relief valve is proposed. First of all. a mathematical model describing the dynamics of a balanced piston type relief valve has been derived. Governing equations such as dynamic equations for the main spool and the pilot spool and flow equations for each orifice are established. The mathematical model is verified by comparing the results of simulation with that of experiments. Furthermore, influences of the parameters on the dynamic characteristics of a relief valve have been investigated by simulation of the proposed model. Major design parameters on the valve response are determined, which affect the system response significantly. And then, using the determined parameters, the optimization of the two stage relief valve by Genetic Algorithm, which is a random search algorithm can find the global optimum without converging local optimum, is performed. The optimal design process of a two stage relief valve is presented to determine the major design parameters. Fitness function reflects the changing pressure according to parameters. It is shown that the genetic algorithms satisfactorily optimized the major design parameters of the two stage relief valve.

• International Journal of Industrial Entomology and Biomaterials
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• 제2권1호
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• pp.79-81
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• 2001

A study was conducted to establish the degree of genetic divergence between different hybrid forms and rearing conditions through estimation of the minimum number of genes (allelic pairs) differentiating parents in terms of specific quantitative traits. It was established that the minimum gene numbers differentiating parental lines in the inheritance of cocoon was 1, of cocoon shell weight- between 1 and 2, and of silk filament length- between 2 and 3. The variability in the specific genetic parameter could be explained by the reliability of the statistical-and-genetic method used and the expression of genes affecting the formation of each of the characters tested. Gene expression, in its turns is conditioned both by the gene interaction within the genotypes and the different genotype response to environmental change. To go deep in the problem, experiments should be conducted under strictly controlled conditions, reducing the mathematical-and-genetic analysis to a physiological levels and hence to analyse the genetic nature of the specific quantitative character formation and its genetic control.