• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.1159-1163
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• 2010

최근의 극심한 기상이변으로 인하여 발생되는 유출량의 예측에 관한 사항은 치수 이수는 물론 방재의 측면에서도 역시 매우 중요한 관심사로 부각되고 있다. 강우-유출 관계는 유역의 수많은 시 공간적 변수들에 의해 영향을 받기 때문에 매우 복잡하여 예측하기 힘든 요소이다. 과거에는 추계학적 예측모형이나 확정론적 예측모형 혹은 경험적 모형 등을 사용하여 유출량을 예측하였으나 최근에는 인공신경망과 퍼지모형 그리고 유전자 알고리즘과 같은 인공지능기반의 모형들이 많이 사용되고 있다. 하지만 유출량을 예측하고자 할 때 학습자료 및 검정자료로써 사용되는 유출량은 수위-유량 관계곡선식으로부터 구하는 경우가 대부분으로 이렇게 유도된 유출량의 경우 오차가 크기 때문에 그 신뢰성에 문제가 있을 것으로 판단된다. 따라서 본 논문에서는 선행우량 및 수위자료로부터 단시간 수위예측에 관해 연구하였다. 신경망은 과거자료의 입 출력 패턴에서 정보를 추출하여 지식으로 보유하고, 이를 근거로 새로운 상황에 대한 해답을 제시하도록 하는 인공지능분야의 학습기법으로 인간이 과거의 경험과 훈련으로 지식을 축적하듯이 시스템의 입 출력에 의하여 연결강도를 최적화함으로서 모형의 구조를 스스로 조직화하기 때문에 모형의 구조에 적합한 최적 매개변수를 추정할 수 있다. 따라서 정확한 예측이 어려운 하천수위를 과거의 자료로 부터 학습된 신경망의 수학적 알고리즘을 통해 유출량의 예측에 적용할 수 있을 것이다. 유전자 알고리즘은 적자생존의 생물학 원리에 바탕을 둔 최적화 기법중의 하나로 자연계의 생명체 중 환경에 잘 적응한 개체가 좀 더 많은 자손을 남길 수 있다는 자연선택 과정과 유전자의 변화를 통해서 좋은 방향으로 발전해 나간다는 자연 진화의 과정인 자연계의 유전자 메커니즘에 바탕을 둔 탐색 알고리즘이다. 즉, 자연계의 유전과 진화 메커니즘을 공학적으로 모델화함으로써 잠재적인 해의 후보들을 모아 군집을 형성한 뒤 서로간의 교배 혹은 변이를 통해서 최적 해를 찾는 계산 모델이다. 따라서 본 연구에서는 인공신경망의 가중치를 유전자 알고리즘에 의해 최적화시킨후 오류역전파알고리즘에 의해 신경망의 학습을 진행하는 모형으로 감천유역의 선산수위표지점의 수위를 1시간~6시간까지 예측하였다.

• Molecules and Cells
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• v.40 no.7
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• pp.450-456
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• 2017

Mammalian physiology and behavior are regulated by an internal time-keeping system, referred to as circadian rhythm. The circadian timing system has a hierarchical organization composed of the master clock in the suprachiasmatic nucleus (SCN) and local clocks in extra-SCN brain regions and peripheral organs. The circadian clock molecular mechanism involves a network of transcription-translation feedback loops. In addition to the clinical association between circadian rhythm disruption and mood disorders, recent studies have suggested a molecular link between mood regulation and circadian rhythm. Specifically, genetic deletion of the circadian nuclear receptor Rev-$erb{\alpha}$ induces mania-like behavior caused by increased midbrain dopaminergic (DAergic) tone at dusk. The association between circadian rhythm and emotion-related behaviors can be applied to pathological conditions, including neurodegenerative diseases. In Parkinson's disease (PD), DAergic neurons in the substantia nigra pars compacta progressively degenerate leading to motor dysfunction. Patients with PD also exhibit non-motor symptoms, including sleep disorder and neuropsychiatric disorders. Thus, it is important to understand the mechanisms that link the molecular circadian clock and brain machinery in the regulation of emotional behaviors and related midbrain DAergic neuronal circuits in healthy and pathological states. This review summarizes the current literature regarding the association between circadian rhythm and mood regulation from a chronobiological perspective, and may provide insight into therapeutic approaches to target psychiatric symptoms in neurodegenerative diseases involving circadian rhythm dysfunction.

• Journal of the Korean Institute of Intelligent Systems
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• v.25 no.2
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• pp.191-196
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• 2015

There have been many studies on statistical forecasting on firm's performance and stock price by applying various financial indicators such as debt ratio and sales growth rate. Selecting predictors for constructing a prediction model among the various financial indicators is very important for precise prediction. Most of the previous studies applied variable selection algorithms for selecting predictors. However, the variable selection algorithm is considered to be at risk of eliminating certain amount of information from the indicators that were excluded from model construction. Therefore, we propose a firm's performance prediction model which principal component analysis is applied instead of the variable selection algorithm, in order to reduce dimensionality of input variables of the prediction model. In this study, we constructed the proposed prediction model by using financial data of American IT companies to empirically analyze prediction performance of the model.

• Journal of the Korean Data and Information Science Society
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• v.25 no.6
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• pp.1385-1395
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• 2014

Economic traits of livestock are affected by environmental factors and genetic factors. In addition, it is not affected by one gene, but is affected by interaction of genes. We used a linear regression model in order to adjust environmental factors. And, in order to identify gene-gene interaction effect, we applied data mining techniques such as neural network, logistic regression, CART and C5.0 using five-SNPs (single nucleotide polymorphism) of FASN (fatty acid synthase). We divided total data into training (60%) and testing (40%) data, and applied the model which was designed by training data to testing data. By the comparison of prediction accuracy, C5.0 was identified as the best model. It were selected superior genotype using the decision tree.

• Korean Journal of Agricultural and Forest Meteorology
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• v.3 no.1
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• pp.37-43
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• 2001

Crop status monitoring and yield prediction at higher spatial resolution is a valuable tool in various decision making processes including agricultural policy making by the national and local governments. A prototype crop forecasting system was developed to project the size of rice crop across geographic areas nationwide, based on daily weather pattern. The system consists of crop models and the input data for 1,455 cultivation zone units (the smallest administrative unit of local government in South Korea called "Myun") making up the coterminous South Korea. CERES-rice, a rice crop growth simulation model, was tuned to have genetic characteristics pertinent to domestic cultivars. Daily maximum/minimum temperature, solar radiation, and precipitation surface on 1km by 1km grid spacing were prepared by a spatial interpolation of 63 point observations from the Korea Meteorological Administration network. Spatial mean weather data were derived for each Myun and transformed to the model input format. Soil characteristics and management information at each Myun were available from the Rural Development Administration. The system was applied to the forecasting of national rice production for the recent 3 years (1997 to 1999). The model was run with the past weather data as of September 15 each year, which is about a month earlier than the actual harvest date. Simulated yields of 1,455 Myuns were grouped into 162 counties by acreage-weighted summation to enable the validation, since the official production statistics from the Ministry of Agriculture and Forestry is on the county basis. Forecast yields were less sensitive to the changes in annual climate than the reported yields and there was a relatively weak correlation between the forecast and the reported yields. However, the projected size of rice crop at each county, which was obtained by multiplication of the mean yield with the acreage, was close to the reported production with the $r^2$ values higher than 0.97 in all three years.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.22 no.5
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• pp.86-94
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• 2008

In this paper proposed the solar tracking system to use a fuzzy based on PC in of order to increase an output of the PV(Photovoltaic) array. The solar tracking system operated two DC motors driving by signal of photo sensor. The control of dual axes is not an easy task due to nonlinear dynamics and unavailability of the parameters. Recently, artificial intelligent control of the fuzzy control, neural-network and genetic algorithm etc. have been studies. The fuzzy control made a nonlinear dynamics to well perform and had a robust and highly efficient characteristic about a parameter variable as well as a nonlinear characteristic. Hence the fuzzy control was used to perform the tracking system after comparing with error values of setting-up, nonlinear altitude and azimuth. In this paper designed a fuzzy controller for improving output of PV array and evaluated comparison with efficient of conventional PI controller. The data which were obtained by experiment were able to show a validity of the proposed controller.

• Journal of the Korean Institute of Intelligent Systems
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• v.18 no.3
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• pp.360-366
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• 2008

The initial fuzzy partitions in fuzzy rule-based classification systems are determined by considering the domain region of each attribute with the given data, and the optimal classification boundaries within the fuzzy partitions can be discovered by tuning their parameters using various learning processes such as neural network, genetic algorithm, and so on. In this paper, we propose a selection method for fuzzy partition based on statistical information to maximize the performance of pattern classification without learning processes where statistical information is used to extract the uncertainty regions (i.e., the regions which the classification boundaries in pattern classification problems are determined) in each input attribute from the numerical data. Moreover the methods for extracting the candidate rules which are associated with the partition intervals generated by statistical information and for minimizing the coupling problem between the candidate rules are additionally discussed. In order to show the effectiveness of the proposed method, we compared the classification accuracy of the proposed with those of conventional methods on the IRIS and New Thyroid Cancer data. From experimental results, we can confirm the fact that the proposed method only considering statistical information of the numerical patterns provides equal to or better classification accuracy than that of the conventional methods.

• Journal of Menopausal Medicine
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• v.24 no.3
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• pp.183-187
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• 2018

Objectives: The present mini review aimed to summarize the existing knowledge regarding the beneficial and adverse effects of raloxifene in menopausal women. Methods: This study is a review of relevant publications about the effects of raloxifene on sleep disorder, depression, venous thromboembolism, the plasma concentration of lipoprotein, breast cancer, and cognitive function among menopausal women. Results: Raloxifene showed no significant effect on depression and sleep disorder. Verbal memory improved with administration of 60 mg/day of raloxifene while a mild cognitive impairment risk reduction by 33% was observed with administration of 120 mg/day of raloxifene. Raloxifene was associated with a 50% decrease in the need for prolapse surgery. The result of a meta-analysis showed a significant decline in the plasma concentration of lipoprotein in the raloxifene group compared to placebo (standardized mean difference, -0.43; 10 trials). A network meta-analysis showed that raloxifene significantly decreased the risk of breast cancer (relative risk, 0.572; 95% confidence interval, 0.327-0.881; P = 0.01). In terms of adverse effects of raloxifene, the odds ratio (OR) was observed to be 1.54 (P = 0.006), indicating 54% increase in the risk of deep vein thrombosis (DVT) while the OR for pulmonary embolism (PE) was 1.05, suggesting a 91% increase in the risk of PE alone (P = 0.03). Conclusions: Raloxifene had no significant effect on depression and sleep disorder but decreased the concentration of lipoprotein. Raloxifene administration was associated with an increased risk of DVT and PE and a decreased risk of breast cancer and pelvic organ prolapse in postmenopausal women.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.47 no.3
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• pp.177-186
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• 2019

Wind power tower has been used to augment the performance of VAWT (Vertical Axis Wind Turbine). However, inappropriately designed wind power tower could reduce the performance of VAWT. Hence, an optimization study was conducted on a wind power tower. Six design variables were selected, such as the outer radius and the inner radius of the guide wall, the adoption of the splitter, the inner radius of the splitter, the number of the guide wall and the circumferential angle. For the objective function, the periodic averaged torque obtained at the VAWT was selected. In the optimization, Design of Experiment (DOE), Genetic Algorithm (GA), and Artificial Neural Network (ANN) have been applied in order to avoid a localized optimized result. The ANN has been continuously improved after finishing the optimization process at each generation. The performance of the VAWT was improved more than twice when it operated within the optimized wind power tower compared to that obtained at a standalone.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.8
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• pp.1084-1094
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• 2019

Objective: The aim of this study was to select the candidate genes affecting meat quality and preliminarily explore the related molecular mechanisms in the Mashen pig. Methods: The present study explored genetic factors affecting meat quality in the Mashen pig using RNA sequencing (RNA-Seq). We sequenced the transcriptomes of 180-day-old Mashen and Large White pigs using longissimus dorsi to select differentially expressed genes (DEGs). Results: The results indicated that a total of 425 genes were differentially expressed between Mashen and Large White pigs. A gene ontology enrichment analysis revealed that DEGs were mainly enriched for biological processes associated with metabolism and muscle development, while a Kyoto encyclopedia of genes and genomes analysis showed that DEGs mainly participated in signaling pathways associated with amino acid metabolism, fatty acid metabolism, and skeletal muscle differentiation. A MCODE analysis of the protein-protein interaction network indicated that the four identified subsets of genes were mainly associated with translational initiation, skeletal muscle differentiation, amino acid metabolism, and oxidative phosphorylation pathways. Conclusion: Based on the analysis results, we selected glutamic-oxaloacetic transaminase 1, malate dehydrogenase 1, pyruvate dehydrogenase 1, pyruvate dehydrogenase kinase 4, and activator protein-1 as candidate genes affecting meat quality in pigs. A discussion of the related molecular mechanisms is provided to offer a theoretical basis for future studies on the improvement of meat quality in pigs.