• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2009년도 춘계 종합학술대회 논문집
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• pp.870-874
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• 2009

추상 이미지를 자동 생성하는 기법으로 유전자 알고리즘을 이용하는 방법은 다양한 형태의 이미지를 자동 생성할 수 있는 기법으로 유용하게 쓰일 수 있다. 그러나 다수의 자동 생성된 이미지를 보관하고 검색하는 과정에서 적절한 분류 방법이 제공되지 않아 관리의 어려움이 존재한다. 본 연구에서는 아핀 추상 이미지를 효과적으로 분류하기 위한 체계로 형태요소, 감성요소, 색채요소를 이용한 분류 방법을 제안하고 이를 검색할 수 있는 데이터베이스를 설계한다.

• 한국동물위생학회지
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• 제39권1호
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• pp.59-63
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• 2016

Duck circovirus (DuCV) has been recognized as a contagious immunosuppressive virus affecting many duck species worldwide. To determine the prevalence of DuCV infection in ducks, we investigated 104 samples collected from 50 duck farms in Jeonbuk province with the polymerase chain reaction (PCR). Among collected samples, 40 (38.5%) were positive for DuCV. The prevalence of DuCV PCR-positive samples increased with age. Genomic sequences of 15 DuCV strains were determined and compared with previously available DuCV sequences in public databases. Phylogenetic analysis revealed that all strains were clustered into DuCV-1 group.

• 한국양식학회지
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• 제14권1호
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• pp.9-16
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• 2001

Characterization of a single pass of cDNA sequence, an expressed sequence tag (EST) has been a fast growing activity in fish genomics. Despite its relatively short history, fish EST databases (dbESTs) have already begun to play a significant role in bridging the gaps in our knowledge on the gene expression in fish genome. This review provides a brief description of the technology for establishing fish dbESTs, its current status, and implication of the ESTs to aquaculture and fisheries science with particular emphasis on the discovery of novel genes for transgenic application, the use of polymorphic EST markers in genetic linkage mapping and the evaluation of signal-responsive gene expression.

• Journal of Genetic Medicine
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• 제10권1호
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• pp.27-32
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• 2013

Post-transcriptional nucleotide sequence modification of transcripts by RNA editing is an important molecular mechanism in the regulation of protein function and is associated with a variety of human disease phenotypes. Identification of RNA editing sites is the basic step for studying RNA editing. Databases and bioinformatics resources are used to annotate and evaluate as well as identify RNA editing sites. No method is free of limitations. Correctly establishing an analytic pipeline and strategic application of both experimental and bioinformatics methods constitute the first step in investigating RNA editing. This review summarizes modern bioinformatics approaches and related resources for RNA editing research.

• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2002년도 추계학술대회
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• pp.3-14
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• 2002

Functional genomics aims at uncovering useful information carried on genome sequences and at using it to understand the mechanisms of biological function. Elucidating the unknown biological functions of new genes based upon the genomics rationales will greatly speed up the extensive understanding of biocatalysis and biodegradation in biological world including microorganisms. DNA microarrays generate a system for the simultaneous measurement of the expression level of thousands of genes in a single hybridization assay. Their data mining (transcriptome) strategy has two categories: differential gene expression and coordinated gene expression. Furthermore, measurement of proteins (proteome) generates information on how the transcribed sequences end up as functional characteristics within the cell, and quantitation of metabolites yields information on how the functional proteins act to produce energy and process substrates (metabolome). Various composite functional genomics databases containing genetic, enzymatic and metabolic information have been developed and will contribute to the understanding of the life blue print and the new discoveries and practices in biocatalysis and biodegradation that could enrich their industrial and environmental applications.

• Plant Biotechnology Reports
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• 제2권2호
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• pp.93-112
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• 2008

Medicinal and aromatic plants (MAPs) are important sources for plant secondary metabolites, which are important for human healthcare. Improvement of the yield and quality of these natural plant products through conventional breeding is still a challenge. However, recent advances in plant genomics research has generated knowledge leading to a better understanding of the complex genetics and biochemistry involved in biosynthesis of these plant secondary metabolites. This genomics research also concerned identification and isolation of genes involved in different steps of a number of metabolic pathways. Progress has also been made in the development of functional genomics resources (EST databases and micro-arrays) in several medicinal plant species, which offer new opportunities for improvement of genotypes using perfect markers or genetic transformation. This review article presents an overview of the recent developments and future possibilities in genetics and genomics of MAP species including use of transgenic approach for their improvement.

• 한국어업기술학회:학술대회논문집
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• 한국어업기술학회 2002년도 추계 수산관련학회 공동학술대회발표요지집
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• pp.181-182
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• 2002

Expressed sequence tags (ESTs) are generated by single-pass DNA sequencing of clones obtained from cDNA libraries and are powerful tool in the genetic characterization of organisms, owing in large part to the speed and affordability of generating these sequences. Comparison of sequences obtained with those available in public sequence databases allows putative identification of many genes. (omitted)

• 한국균학회소식:학술대회논문집
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• 한국균학회 2018년도 춘계학술대회 및 임시총회
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• pp.51-51
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• 2018

The application of recombinant DNA technology has been remarkable and nearly replaced commonly used traditional methods. Traditional industrial microbiology long depended on the discovery of valuable strains and mutagenesis of such strains to improve its secretion capacity of enzymes and secondary metabolites on the industrial scale. Commodities included industrial enzymes and biopharmaceuticals. The purpose of genome manipulation by the crossing of different strains or genetic recombination of naked DNA to the genome is of increased production of valuable metabolites. We optimized a transformation method to either for removal of innate genes, introduction of heterologous genes, or combination of both. We have been used selected whole or partial genes to manipulate target fungi toward the development of strains overproducing invaluable proteins. We have also used the whole genome sequence information of fungal genomes in public databases and functional genomics approach to select genes to manipulate and eventually contributing greatly to the development of overproducing industrial strains overproducing proteins or secondary metabolites. I will briefly review 1) filamentous fungi as a host for production of recombinant proteins and secondary metabolites, 2) markets of industrial metabolites, 3) a new approach to manipulate up to five genes at the same time in the system that ProxEnrem uses.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(4)
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• pp.335-338
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• 2002

This paper proposes some technical approaches for automatic detection of pulmonary nodules in chest X-ray images. We applied threshold technique for the lung field segmentation and extended the lung field by using morphological methods. A template matching technique was employed for automatic detecting nodules in lung area. Genetic algorithm(GA) was used in template matching(TM) to select a matched image from various reference patterns(simulated typical nodules). We eliminated the false-positive candidates by using histograms and contrasts. We used standard databases published by Japanese Society of Radiological Technology (JSRT) for correct results. Also we employ two-dimensional Gaussian distribution for some reference images because the shadow of lung nodules in radiogram generally shows the distributions. Nodules of about 89% were correctly detected by our scheme. The simulation results show that it is an effective method to indicate lesions on chest radiograms.

• 정보기술과데이타베이스저널
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• 제5권1호
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• pp.1-12
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• 1998

분산 환경에서 데이터의 할당(allocation)는 중요한 설계 이슈이다. 데이터의 할당은 분산 데이터에 대한 비용(cost) 감소, 성능(performance) 및 가용성(availability) 향상 등의 이점을 극대화할 수 있도록 최적화되어야 한다. 기존 연구들의 대부분은 트랜잭션의 수행 비용을 최소화하는 방향으로만 최적화된 데이터 할당 결과를 제시하고 있다. 즉, 비용, 성능 및 가용성을 모두 함께 고려하는 연구는 아직까지 제시된 결과가 없으며 이는 복잡한 모델에 대한 적절한 최적화 기법이 없기 때문이다. 본 연구에서는 분산 데이터의 이점들인 비용, 성능 및 가용성 등의 다중측면을 동시에 고려함으로써 데이터 할당에 대한 파레토 최적해를 제공하는 DAMMA (Data Allocation Methodology considering Multiple Aspects) 방법론을 제안하였다. DAMMA 방법론은 데이터 분할 과정을 통하여 생성된 최적의 단편들을 분산 시스템의 운용 비용, 수행 성능, 가용성 등의 요소를 고려하여 각 물리적 사이트에 중복 할당하는 파레토 최적해들을 생성해낼 수 있는 설계 방법론이다.