• Title/Summary/Keyword: genetic correlation

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Assessment of Teak (Tectona grandis Linn. f.) Provenance Tests in the Bago Yoma Region, Myanmar

  • Lwin, Ohn;Hyun, Jung-Oh;Yahya, Andi Fadly
    • Journal of Korean Society of Forest Science
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    • v.99 no.5
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    • pp.686-692
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    • 2010
  • This study described the general pattern of genetic variation among ten teak (Tectona grandis Linn. f.) provenances in Myanmar and determined the most suitable seed sources for the plantation program in Bago Yoma region. Seeds of ten provenances were collected to cover the whole teak natural distribution in Myanmar and planted at four trial sites in Bago Yoma region in 1998. Seven years after planting, variation was assessed for growth, morphological characteristics and their correlation with geoclimatic factors. Statistical analysis using ANOVA revealed that there were significant differences in most of the traits measured among provenances, trial sites and provenance ${\times}$ site interaction at five percent level. A positive significant correlation (p<0.01) was found among most of the traits. The regression analyses between all traits and geoclimatic factors indicated the existence of ecoclinal variation in teak. Most of the traits were negatively correlated with the latitude while a positive significant correlation was found between longitude and C/B ratio, crown-diameter, average branch angle and leaf-remain. There was no significant correlation between the mean temperature and any other traits in this study. Furthermore, growth traits and crown diameter were positively correlated with the mean annual rainfall while negative correlation was found between the geographical distance and growth traits. Results indicate that the latitudinal pattern of teak genetic variations in growth performance was attributed to the limit of mean annual rainfall. Comparative assessment showed that local provenances were generally the best and could be use as suitable seed sources for the plantation program in the Bago Yoma region.

The Development of Genetic Fuzzy System for Estimating Link Traveling Speed (주행속도 추정을 위한 Genetic Fuzzy System의 개발)

  • Youn, Yeo-Hun;Lee, Hong-Chul;Kim, Yong-Sik
    • Journal of Korean Institute of Industrial Engineers
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    • v.29 no.1
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    • pp.32-40
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    • 2003
  • In this study, we develop the Genetic Fuzzy System(GFS) to estimate the link traveling speed. Based on the genetic algorithm, we can get the fuzzy rules and membership functions that reflect more accurate correlation between traffic data and speed. From the fact that there exist missing links that lack traffic data, we added a Case Base Reasoning(CBR) to GFS to support estimating the speed of missing links. The case base stores the fuzzy rules and membership functions as its instances. As cases are accumulated, the case base comes to offer appropriate cases to missing links. Experiments show that the proposed GFS provides the more accurate estimation of link traveling speed than existing methods.

Simple Statistical Tools to Detect Signals of Recent Polygenic Selection

  • Piffer, Davide
    • Interdisciplinary Bio Central
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    • v.6 no.1
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    • pp.1.1-1.6
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    • 2014
  • A growing body of evidence shows that most psychological traits are polygenic, that is they involve the action of many genes with small effects. However, the study of selection has disproportionately been on one or a few genes and their associated sweep signals (rapid and large changes in frequency). If our goal is to study the evolution of psychological variables, such as intelligence, we need a model that explains the evolution of phenotypes governed by many common genetic variants. This study illustrates simple statistical tools to detect signals of recent polygenic selection: a) ANOVA can be used to reveal significant deviation from random distribution of allele frequencies across racial groups. b) Principal component analysis can be used as a tool for finding a factor that represents the strength of recent selection on a phenotype and the underlying genetic variation. c) Method of correlated vectors: the correlation between genetic frequencies and the average phenotypes of different populations is computed; then, the resulting correlation coefficients are correlated with the corresponding alleles' genome-wide significance. This provides a measure of how selection acted on genes with higher signal to noise ratio. Another related test is that alleles with large frequency differences between populations should have a higher genome-wide significance value than alleles with small frequency differences. This paper fruitfully employs these tools and shows that common genetic variants exhibit subtle frequency shifts and that these shifts predict phenotypic differences across populations.

Investigation of Biases for Variance Components on Multiple Traits with Varying Number of Categories in Threshold Models Using Bayesian Inferences

  • Lee, D.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.7
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    • pp.925-931
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    • 2002
  • Gibbs sampling algorithms were implemented to the multi-trait threshold animal models with any combinations of multiple binary, ordered categorical, and linear traits and investigate the amount of bias on these models with two kinds of parameterization and algorithms for generating underlying liabilities. Statistical models which included additive genetic and residual effects as random and contemporary group effects as fixed were considered on the models using simulated data. The fully conditional posterior means of heritabilities and genetic (residual) correlations were calculated from 1,000 samples retained every 10th samples after 15,000 samples discarded as "burn-in" period. Under the models considered, several combinations of three traits with binary, multiple ordered categories, and continuous were analyzed. Five replicates were carried out. Estimates for heritabilities and genetic (residual) correlations as the posterior means were unbiased when underlying liabilities for a categorical trait were generated given by underlying liabilities of the other traits and threshold estimates were rescaled. Otherwise, when parameterizing threshold of zero and residual variance of one for binary traits, heritability estimates were inflated 7-10% upward. Genetic correlation estimates were biased upward if positively correlated and downward if negatively correlated when underling liabilities were generated without accounting for correlated traits on prior information. Residual correlation estimates were, consequently, much biased downward if positively correlated and upward if negatively correlated in that case. The more categorical trait had categories, the better mixing rate was shown.

Genetic Relationship between Milk Production, Calving Ease and Days Open at First Parity in Holstein Cows

  • Lee, D.H.;Han, K.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.2
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    • pp.153-158
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    • 2004
  • Data containing 14,188 lactation and reproductive records of Korean Holstein cows at first parity distributed across 3,734 herd-year-season groups were analyzed to get genetic (co)variance estimates for milk yield, fat yield, calving ease, and days open. Milk and Fat yields were adjusted to 305 d. Heritabilities and genetic correlations were estimated in two different animal models on which were included direct genetic effects (Model 1) and direct+maternal genetic effects (Model 2) using REML algorithms. Milk and fat yields were affected by age at first calving as linear and quadratic. Heritability estimates of direct effects were 0.25 for milk yield, 0.17 for fat yield, 0.03 for calving ease and 0.03 for days open in Model 2. These estimates for maternal effects were 0.05, 0.08, 0.04 and less than 0.01 for each corresponding trait. Milk productions at first lactation were to show genetically favorable correlation with calving ease and days open for direct genetic effects (-0.24 - -0.11). Moreover, calving ease was correlated with days open of 0.30 for direct genetic effects. Correlations between direct and maternal effects for each trait were negatively correlated (-0.63 - -0.32). This study suggested that maternal additive genetic variance would be not ignorable for genetic evaluation of milk production as well as reproductive traits such as calving ease and days open at first parity. Furthermore, difficult calving would genetically influence the next conception.

Sire-maternal Grandsire Model and Sire Model in Estimation of Genetic Parameters for Average Daily Gain and Carcass Traits of Japanese Black Cattle

  • Kim, Jong-Bok;Lee, Chaeyoung;Tsuyuki, Tsutomu;Shimogiri, Takeshi;Okamoto, Shin;Maeda, Yoshizane
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.12
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    • pp.1678-1684
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    • 2006
  • The objectives of this study were to estimate genetic parameters and sire breeding values for average daily gain (ADG) and carcass traits using sire-maternal grandsire model with REML approach, sire model with REML approach, sire model without relationships among sires and with REML and ANOVA approach, and to investigate advantages and disadvantages of these methods. Data were collected from 42,325 Japanese Black steers and heifers finished and slaughtered from 1991 to 2004. Traits analyzed in this study were average daily gain (ADG) during the fattening period, live weight at slaughter (LW), cold carcass weight (CW), estimated lean yield percentage (LYE), longissimus muscle area (LMA), subcutaneous fat thickness (SFT), rib thickness (RT), and marbling score (BMS). Bivariate analyses were also performed to obtain genetic and phenotypic correlation coefficients among traits. Estimated breeding values were obtained from each model, and simple and rank correlations among breeding values from each model were calculated. Estimates of heritability using the four models ranged from 0.25 to 0.31 in ADG, from 0.21 to 0.24 in LW, from 0.23 to 0.27 in CW, from 0.10 to 0.17 in DP, from 0.40 to 0.42 in LYE, from 0.19 to 0.31 in LMA, from 0.31 to 0.34 in SFT, from 0.26 to 0.33 in RT, and from 0.18 to 0.44 in BMS. The differences in heritability estimates using the four models seemed to be feasible in ADG, CW, DP, LMA, RT, and BMS. Genetic correlation coefficients of ADG with CW, SFT, RT and BMS were moderate to high and positive while the genetic correlation coefficients between ADG and LYE was low and negative. Correlation coefficients of BMS with SFT were negligible for both genetic and phenotypic correlations. The correlations of estimates evaluated from sire models with those from sire-maternal grandsire model were not large enough to convincing that breeding values using a sire model were corresponding to those using a sire-maternal grand sire model. If information of maternal grand sires are not available, the sire model with incomplete pedigree information included only sire of sire (Model 2) is optimal among the sire models evaluated in this study.

Estimates of Genetic Parameter for Carcass Traits and Chemical Composition Analysis in Hanwoo (한우 도체형질 및 도체 일반성분 유전모수 추정)

  • Roh, Seung Hee;Kim, Jin Won;Lee, Sung Soo;Lee, Eun Joo;Park, Byoungho;Choi, Taejeong;Park, Mi Na;Lee, Jung Gyu
    • Journal of agriculture & life science
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    • v.51 no.4
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    • pp.111-119
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    • 2017
  • The objective of this study is to check the applicability of the improved trait through the nutritional value of loin and the estimation of genetic parameter through the chemical composition analysis(moisture, crude fat, crude protein, crude ash) for Hanwoo carcass traits and loin. The data of 1kg of loin sampled and analyzed for 2,033 Hanwoo progeny test(steers) from $47^{th}$ to $57^{th}$ were used as the disclosure material used in this study. The study resulted that the heritability for carcass weight, eye muscle area, back fat thickness and marbling score which are Hanwoo carcass traits was estimated to be 0.37, 0.51, 0.44 and 0.57, respectively and the heritability for moisture, crude fat, crude protein and crude ash which are the chemical composition analysis to be 0.62, 0.64, 0.58 and 0.12, respectively. And the genetic correlation estimate between carcass weight and crude fat was 0.35, and marbling score with moisture, crude fat, crude protein and crude ash was -0.966, 0.964, -0.924 and -0.664, respectively. The genetic correlation between moisture and crude fat, crude protein was analyzed to be -0.998, 0.969 and a high genetic correlation was shown in crude fat and crude protein, -0.979. As the chemical composition analysis value showed high heritability in moisture, crude fat and crude protein, improved traits are considered to be available.

Estimation of Genetic Parameters on Pre-weaning Growth Traits in Hanwoo (한우의 이유전 성장형질에 관한 유전모수 추정)

  • Hwang, J.M.;Choi, J.G.;Kim, H.C.;Choy, Y.H.;Lee, C.;Yang, B.K.;Shin, J.S.;Kim, Jong-Bok
    • Journal of Animal Science and Technology
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    • v.49 no.2
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    • pp.171-176
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    • 2007
  • A total of 4,627 records on pre-weaning growth traits, birth weight(BW), weaning weight(WW) and pre-weaning daily gain(ADG) of Hanwoo’s born form 1970 to 2005 were collected from Hanwoo Experiment Station, National Livestock Research Institute. Variance components and heritabilities of BW, WW and ADG were estimated with two models; Model 1 included only direct genetic effect while Mode1 2 included direct genetic, maternal genetic and permanent environmental effects. Direct herit- ability estimates of BW, WW and ADG estimated by model 1 were 0.34, 0.26 and 0.20, respectively. In model 2, direct heritability and maternal genetic heritability estimates were 0.14 and 0.06 for BW, 0.07 and 0.04 for WW and 0.05 and 0.04 for ADG. Estimates of genetic correlation between direct and maternal effect for BW, WW and ADG were 0.58, 0.75 and 0.61, respectively. Genetic correlation coefficients between BW and WW, between BW and ADG, and between WW and ADG were 0.76, 0.62 and 0.99, respectively.

Association of ABO Genetic Polymorphisms and Dyslipidemia in Korean Population (한국인 ABO 유전자 다형성과 이상지질혈증의 연관성)

  • Yoon-Joo SONG;Sung Won LEE;Hyun-Seok JIN;Sangwook PARK
    • Korean Journal of Clinical Laboratory Science
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    • v.56 no.1
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    • pp.66-72
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    • 2024
  • Lipid metabolic disorders are commonly encountered in clinical practice. Dyslipidemia and its prevalence rate are strongly associated with the morbidity and mortality of cardiovascular disease worldwide. We conducted a genetic analysis to determine the association between genetic polymorphisms of the ABO gene in adults middle-aged (40~69 years) with dyslipidemia in the Korean population. A total of 6,750 subjects from the Korea Association REsource (KARE) were selected for this study. Using the genetic and epidemiologic data of 4,403 dyslipidemia cases and 2,347 normal controls from the KARE, single nucleotide polymorphisms (SNPs) in ABO gene were analyzed for their genetic correlation. Eleven SNPs out of the ABO gene demonstrated a statistically significant association with dyslipidemia. Among them, rs8176707 in ABO gene statistically showed the most significant correlation with dyslipidemia (P-value=0.002, odds ratio=0.82, 95% confidence interval=0.78~0.86). The minor allele of T polymorphism within the ABO intron genetic region was associated with a decreased risk of dyslipidemia. This study uncovered a significant association between genetic polymorphism in the ABO gene and dyslipidemia. This finding suggest that ABO SNPs markers have a genetic correlation with the etiology of dyslipidemia.

Genetic parameters for residual feed intake in a random population of Pekin duck

  • Zhang, Yunsheng;Guo, Zhan Bao;Xie, Ming;Zhang, Zhiying;Hou, Shuisheng
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.2
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    • pp.167-170
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    • 2017
  • Objective: The feed intake (FI) and feed efficiency are economically important traits in ducks. To obtain insight into this economically important trait, we designed an experiment based on the residual feed intake (RFI) and feed conversion ratio (FCR) of a random population Pekin duck. Methods: Two thousand and twenty pedigreed random population Pekin ducks were established from 90 males mated to 450 females in two hatches. Traits analyzed in the study were body weight at the 42th day (BW42), 15 to 42 days average daily gain (ADG), 15 to 42 days FI, 15 to 42 days FCR, and 15 to 42 days RFI to assess their genetic interrelationships. The genetic parameters for feed efficiency traits were estimated using restricted maximum likelihood (REML) methodology applied to a sire-dam model for all traits using the ASREML software. Results: Estimates heritability of BW42, ADG, FI, FCR, and RFI were 0.39, 0.38, 0.33, 0.38, and 0.41, respectively. The genetic correlation was high between RFI and FI (0.77) and moderate between RFI and FCR (0.54). The genetic correlation was high and moderate between FCR and ADG (-0.80), and between FCR and BW42 (-0.64), and between FCR and FI (0.49), respectively. Conclusion: Thus, selection on RFI was expected to improve feed efficiency, and reduce FI. Selection on RFI thus improves the feed efficiency of animals without impairing their FI and increase growth rate.