• Title/Summary/Keyword: generalized

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Early Onset Renal Failure in Congenital Nephrotic Syndrome associated with Congenital Diaphragmatic Hernia by WT1 Gene Mutation (WT1 유전자 돌연변이에 의해 선천성 가로막 탈장이 동반되고 조기 신부전이 초래된 선천성 신증후군 1례)

  • Park, Yong-Jun;Oh, Jin-Won;Choi, Kyong-Min;Kim, Pyung-Kil;Lee, Jong-In;Song, Ji-Sun
    • Childhood Kidney Diseases
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    • v.13 no.1
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    • pp.84-91
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    • 2009
  • We experienced a female neonate with congenital nephrotic syndrome (CNS) associated with congenital diaphragmatic hernia (CDH). Because of the rare combination of two conditions, we report this case with literature review. CDH was found immediately after birth and emergency operation was done for hernia repair. But on the next day, generalized edema and oliguria(0.59 mL/kg/hour) was found and her blood chemistry showed hypoalbuminemia (1.6 g/dL), increased BUN (27.7 mg/dL) and serum creatinine( 1.8 mg/dL) along with heavy proteinuria (4+). We started albumin infusion with a bolus of intravenous furosemide. We suspected the neonate had congenital nephrotic syndrome and her 24hr urine protein was 1,816 mg/day. In spite of immunosuppressive therapy, the nephrotic syndrome and renal failure progressed. We started peritoneal dialysis on the day of life 22 but it was not satisfactory. She was complicated by intracranial hemorrhage and multi-organ failure and expired at 34 days of age. Kidney necropsy was performed which showed diffuse mesangial sclerosis (DMS). Her chromosome study revealed 46, XX and her gene study revealed a heterozygous missense mutation, Arg366His, in Wilms tumor suppressor gene (WT1). This case deserves attention on account of the 4th case of CNS with CDH revealing the Arg366His mutation in the WT1 gene and G the 1st case of early onset renal failure without male pseudohermaphroditism and Wilms tumor with CNS, CDH and the Arg366His mutation in the WT1 gene. So, this report gives support to the hypothesis that Arg366His mutation in the WT1 gene can result in CNS and CDH.

Hybrid Minimum Spanning Tree Algorithm (하이브리드 최소신장트리 알고리즘)

  • Lee, Sang-Un
    • The KIPS Transactions:PartA
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    • v.17A no.3
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    • pp.159-166
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    • 2010
  • In this paper, to obtain the Minimum Spanning Tree (MST) from the graph with several nodes having the same weight, I applied both Bor$\dot{u}$vka and Kruskal MST algorithms. The result came out to such a way that Kruskal MST algorithm succeeded to obtain MST, but not did the Prim MST algorithm. It is also found that an algorithm that chooses Inter-MSF MWE in the $2^{nd}$ stage of Bor$\dot{u}$vka is quite complicating. The $1^{st}$ stage of Bor$\dot{u}$vka has an advantage of obtaining Minimum Spanning Forest (MSF) with the least number of the edges, and on the other hand, Kruskal MST algorithm has an advantage of always obtaining MST though it deals with all the edges. Therefore, this paper suggests an Hybrid MST algorithm which consists of the merits of both Bor$\dot{u}$vka's $1^{st}$ stage and Kruskal MST algorithm. When applied additionally to 6 graphs, Hybrid MST algorithm has a same effect as that of Kruskal MST algorithm. Also, comparing the algorithm performance speed and capacity, Hybrid MST algorithm has shown the greatest performance Therefore, the suggested algorithm can be used as the generalized MST algorithm.

A CLINICAL REVIEW ON THE DELAYED ERUPTION OF 1ST MOLARS (제1대구치의 맹출지연에 관한 임상적 고찰)

  • Kim, Ju-Mi;WhangBo, Min;Kim, Joo-Young;Eum, Jong-Hyuk;Rhee, Ae-Ryon;Kim, Shin;Seo, Soo-Jeong
    • Journal of the korean academy of Pediatric Dentistry
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    • v.21 no.2
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    • pp.555-560
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    • 1994
  • Among the permanent teeth. the first permanent molars play the greatest role in occlusion and function. So, the congenital missing, abnormal reuption or abnormal formation of the first permanent molars in the course of arch development would inflict normal development of dental arches. Therefore, early detection of abnormal cases related to first permanent molars and understanding of current and predictable clinical problems are essential for proper occlusal guidance in children. With the aim of investigating the clinical patterns of delayed eruption of first permanent molars in children, panoramic tomograms of the childern in mixed and early permanent dentition were observed and analyzed. The results were as follows: 1. Among the delayed eruption of first permanent molars, on tooth or bilateral teeths were affected most frequently. Delayed eruption was more prevalent in maxilla than in mandible. 2. The formation of tardily erupted teeth were also delayed. 3. Delayed eruption was generally limited in first molars or molar segments. 4. Delayed eruption of first permanent molars is accompanied by abnormal position of tooth germs, for example, ectopic eruption, delayed dental age, delayed localized tooth formation and generalized congenital missing. 5. There was a tendency of delayed formation or congenital missing of second molars distal to tardily erupted 1st molars. And that was more marked in maxilla than in mandible. 6. There was reported that affected 1st molars show various size and shapes. Maxillary 1st molars showing delayed eruption showed a tendency of having 3 cusps. But, tardily erupted mandibular 1st molars showed no significant reduction in mesiodistal dimension, as reported. 7. In some cases, the delayed eruption of 1st permanent molars was associated with ectopic eruption, but their formation was not usually retarded. 8. In skeletal class III cases, there showed a tendency of mandibular 1st molars to erupt earlier than maxillary 1st molars with greater interval than in normal occlusion.

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A Modeling Study on the AVO and Complex Trace Analyses of the Fracture Bone Reflection (파쇄대 반사에너지의 AVO 및 복소트레이스 분석에 관한 모형연구)

  • Han Soo-Hyung;Kim Ji-Soo;Ha Hee-Sang;Min Dong-Joo
    • Geophysics and Geophysical Exploration
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    • v.2 no.1
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    • pp.33-42
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    • 1999
  • AVO and complex trace analyses mainly used to characterize natural gas reservoir were tested in this paper for a possible application to detection of major geological discontinuities such as fracture zones. The test data used in this study were calculated by utilizing a viscoelastic numerical program which was based on the generalized Maxwell body for a horizontal fracture model. In AVO analysis of a horizontal fracture zone, p-wave reflection appears to be variant depending upon the acoustic-impedence contrast and the offset distance. The fracture zone is also effectively clarified both in gradient stack and range-limited stack in which fracture zone reflection is attenuated with the increasing offset distance. In complex attribute plots (instantaneous amplitude, frequency, and phase), the top and bottom of the fracture Tone are characterized by a zone of strong amplitudes and an event of the same phase. Low frequency characteristics appear at the fracture zone and the underneath. Amplitude attenuation and waveform dispersion are dependent on Q-contrast between the fracture zone and the surrounding media. They were properly compensated by optimum inverse Q-filtering.

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Direct Retargeting Method from Facial Capture Data to Facial Rig (페이셜 리그에 대한 페이셜 캡처 데이터의 다이렉트 리타겟팅 방법)

  • Cho, Hyunjoo;Lee, Jeeho
    • Journal of the Korea Computer Graphics Society
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    • v.22 no.2
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    • pp.11-19
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    • 2016
  • This paper proposes a method to directly retarget facial motion capture data to the facial rig. Facial rig is an essential tool in the production pipeline, which allows helping the artist to create facial animation. The direct mapping method from the motion capture data to the facial rig provides great convenience because artists are already familiar with the use of a facial rig and the direct mapping produces the mapping results that are ready for the artist's follow-up editing process. However, mapping the motion data into a facial rig is not a trivial task because a facial rig typically has a variety of structures, and therefore it is hard to devise a generalized mapping method for various facial rigs. In this paper, we propose a data-driven approach to the robust mapping from motion capture data to an arbitary facial rig. The results show that our method is intuitive and leads to increased productivity in the creation of facial animation. We also show that our method can retarget the expression successfully to non-human characters which have a very different shape of face from that of human.

Classification Schemes of Precast Beam-Column Connections According to Contribution of Deformation Components (변형기여분에 따른 프리캐스트 보-기둥 접합부의 분류방안)

  • Choi, Hyun-Ki;Choi, Chang-Sik
    • Journal of the Korea Concrete Institute
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    • v.26 no.4
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    • pp.545-553
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    • 2014
  • This study suggested an integrated classification method for generalized characteristics of PC beam-column connection according to connection details. Quantifying the failure mode of PC-beam column connection and characteristics of corresponding details, this study suggested to use deformation contribution of each element of beam-column assemblage. According to the expected failure mode of beam-column connection assemblage, PC beam-column connection can be classified into 'equivalent monolithic system' and 'jointed system'. In this study, four test specimens were tested for verification of detailed classification method of PC beam-column connections. Test was carried out with typical beam-column connection test method. Load was applied at the top of test specimen and end of beams were restrained by hinge. In order to verify the deformation contribution of each test specimen, 34-LVDTs were mounted on test specimen. According to test results, deformation contribution of each test specimen have different characteristics. Deformation characteristics of joint and other components which are quantified by test results, equivalent monolithic system can be classified into two categories. Strong connection have extremely small deformation contribution of joint and much larger deformation contribution was shown in flexural behavior of beam. The other type of beam-column connection is ductile connection which allows the larger deformation in joint area compared with strong connection.

Recurrent Extraventricular Neurocytoma with Malignant Glial Differentiation - Case Report - (악성신경교 분화를 보이는 재발성 뇌실외 신경세포종 - 증례보고-)

  • Chang, In-Bok;Park, Se-Hyuck;Hwang, Hyung-Sik;Kim, Duck-Hwan;Nam, Eun Sook;Cho, Byung-Moon;Shin, Dong-Ik;Oh, Sae-Moon
    • Journal of Korean Neurosurgical Society
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    • v.30 no.4
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    • pp.522-527
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    • 2001
  • We present a case of recurrent extraventricular neurocytoma with malignant glial differentiation in left temporoparietal area. A 37-year-old man with presentation of generalized seizure had undergone biopsy of brain tumor in left parietal area in 1987, which revealed extraventricular neurocytoma and radiotherapy was followed. Postoperative course was uneventful until eleven years after biopsy, when he became gradually aphasic and right hemiplegic. Brain CT and MRI revealed enlargement of tumor with peritumoral edema and calcifications. He underwent subtotal tumor removal in 1998. Microscopic examination of second biopsy specimen revealed presence of large areas composed of anaplastic glial cells with frequent mitosis, nuclear pleomorphism, large eosinophilic cytoplasm and eccentric nuclei, resembling gemistocytes, which were strongly immunoreactive to glial fibrillary acidic protein(GFAP) but not to synaptophysin(SNP). Also focal areas of neuronal cells were found, which were immunoreactive to SNP but not to GFAP. These histologic findings imply that this recurred tumor was a high grade, mixed tumor with divergent differentiation of neuronal and astrocyte lineage. We report a rare case of extraventricular cerebral neurocytoma with malignant glial differentiation with review of the literature.

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The Influence of Medical Workers' Emotional Labor on Somatic Symptoms -Focusing on Mediating Effects of Depression and Anxiety- (의료 종사자의 감정노동이 신체증상에 미치는 영향 -우울 및 불안의 매개효과를 중심으로-)

  • Lee, Jung-Min;Jang, Ki-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.11
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    • pp.586-594
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    • 2020
  • The purpose of this study is to propose interventions on emotional labor and health issues through verifying the mediating effects of depression and anxiety on the relationship between emotional labor and somatic symptoms in medical workers. For this study, a sample of 200 medical workers completed the questionnaires of the Korean Emotional Labor Scale, the Patient Health Questionnaire-15, the Patient Health Questionnaire-9, and the Generalized Anxiety Disorder-7. The data was analyzed using the SPSS 25.0 program. The results of this study can be summarized as follows. 1. Results showed a risk of emotional labor, depression, and somatic symptoms in medical workers. 2. The risk group of the emotional labor's 4 factors (excluding organizational support and protection system) had a significantly higher level of depression compared with the normal group. Particularly in emotional dissonance and impairment, depression in the risk group was moderate, while depression in the normal group was normal. 3. Only emotional dissonance and impairment had a significant influence on somatic symptoms. Reflecting the results, the mediating effects of depression and anxiety on the relationship between emotional dissonance and impairment and somatic symptoms were verified. Results showed that depression had a partial mediating effect, whereas anxiety did not have a mediating effect. Finally, we discuss the necessity of dealing with emotional dissonance and depression in emotional labor and health issues.

Inferring and Visualizing Semantic Relationships in Web-based Social Network (웹 기반 소셜 네트워크에서 시맨틱 관계 추론 및 시각화)

  • Lee, Seung-Hoon;Kim, Ji-Hyeok;Kim, Heung-Nam;Jo, Geun-Sik
    • Journal of Intelligence and Information Systems
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    • v.15 no.1
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    • pp.87-102
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    • 2009
  • With the growth of Web 2.0, lots of services allow yours to post their personal information and useful knowledges on networked information spaces such as blogs and online communities etc. As the services are generalized, recent researches related to social network have gained momentum. However, most social network services do not support machine-processable semantic knowledge, so that the information cannot be shared and reused between different domains. Moreover, as explicit definitions of relationships between individual social entities do not be described, it is difficult to analyze social network for inferring unknown semantic relationships. To overcome these limitations, in this paper, we propose a social network analysis system with personal photographic data up-loaded by virtual community users. By using ontology, an informative connectivity between a face entity extracted from photo data and a person entity which already have social relationships was defined clearly and semantic social links were inferred with domain rules. Then the inferred links were provided to yours as a visualized graph. Based on the graph, more efficient social network analysis was achieved in online community.

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Analysis of Error Types in the Differential Problem Solving Progress (미분 문제해결 과정에서의 오류 분석)

  • Jun, Young-Bae;Roh, Eun-Hwan;Choi, Jung-Sook;Kim, Dae-Eui;Jeong, Eui-Chang;Jung, Chan-Sik;Kim, Chang-Su
    • Journal of the Korean School Mathematics Society
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    • v.12 no.4
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    • pp.545-562
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    • 2009
  • Calculus is used in various parts of human life and the basis of social science such as economics and public administration. Yet that is still considered important in the field of science and technology only, and there have been a lot of disputes on that phenomenon. Fortunately, calculus is going to be taught as part of the academic high school second-year mathematics curriculum in and after 2010. Students who face calculus for the first time should be helped not to lose interest in differentiation learning, not to be apprehensive of it nor to avoid it. The purpose of this study was to examine the types of errors made by students in the course of solving differentiation problems in an effort to lay the foundation for differentiation education. A pilot test was conducted after generalized differentiation problems to which students were usually exposed were selected, and experts were asked to review the pilot test. And then a finalized test was implemented to make an error analysis according to an error type analysis framework to serve the purpose.

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