• Title/Summary/Keyword: gas diffusion

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Preventing Extracellular Diffusion of Trigeminal Nitric Oxide Enhances Formalin-induced Orofacial Pain

  • Jung, Hwi-Seok;Jeon, Hong-Bin;Jeon, Ik-Sung;Lee, Bum-Jun;Yoo, Hyun-Woo;Ahn, Dong-Kuk;Youn, Dong-Ho
    • The Korean Journal of Physiology and Pharmacology
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    • v.13 no.5
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    • pp.379-383
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    • 2009
  • Nitric oxide (NO), a diffusible gas, is produced in the central nervous system, including the spinal cord dorsal horn and the trigeminal nucleus, the first central areas processing nociceptive information from periphery. In the spinal cord, it has been demonstrated that NO acts as pronociceptive or antinociceptive mediators, apparently in a concentration-dependent manner. However, the central role of NO in the trigeminal nucleus remains uncertain in support of processing the orofacial nociception. Thus, we here investigated the central role of NO in formalin (3%)-induced orofacial pain in rats by administering membrane-permeable or -impermeable inhibitors, relating to the NO signaling pathways, into intracisternal space. The intracisternal pretreatments with the NO synthase inhibitor L-NAME, the NO-sensitive guanylate cyclase inhibitor ODQ, and the protein kinase C inhibitor GF109203X, all of which are permeable to the cell membrane, significantly reduced the formalin-induced pain, whereas the membrane-impermeable NO scavenger PTIO significantly enhanced it, compared to vehicle controls. These data suggest that an overall effect of NO production in the trigeminal nucleus is pronociceptive, but NO extracellularly diffused out of its producing neurons would have an antinociceptive action.

Characteristics of the Plasma Source for Ground Ionosphere Simulation Surveyed by Disk-Type Langmuir Probe

  • Ryu, Kwangsun;Lee, Junchan;Kim, Songoo;Chung, Taejin;Shin, Goo-Hwan;Cha, Wonho;Min, Kyoungwook;Kim, Vitaly P.
    • Journal of Astronomy and Space Sciences
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    • v.34 no.4
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    • pp.343-352
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    • 2017
  • A space plasma facility has been operated with a back-diffusion-type plasma source installed in a mid-sized vacuum chamber with a diameter of ~1.5 m located in Satellite Technology Research Center (SaTReC), Korea Advanced Institute of Science and Technology (KAIST). To generate plasma with a temperature and density similar to the ionospheric plasma, nickel wires coated with carbonate solution were used as filaments that emit thermal electrons, and the accelerated thermal electrons emitted from the heated wires collide with the neutral gas to form plasma inside the chamber. By using a disk-type Langmuir probe installed inside the vacuum chamber, the generation of plasma similar to the space environment was validated. The characteristics of the plasma according to the grid and plate anode voltages were investigated. The grid voltage of the plasma source is realized as a suitable parameter for manipulating the electron density, while the plate voltage is suitable for adjusting the electron temperature. A simple physical model based on the collision cross-section of electron impact on nitrogen molecule was established to explain the plasma generation mechanism.

Effect of DC Bias on the Growth of Nanocrystalline Diamond Films by Microwave Plasma CVD (마이크로웨이브 플라즈마 CVD에 의한 나노결정질 다이아몬드 박막 성장 시 DC 바이어스 효과)

  • Kim, In-Sup;Kang, Chan Hyoung
    • Journal of the Korean institute of surface engineering
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    • v.46 no.1
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    • pp.29-35
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    • 2013
  • The effect of DC bias on the growth of nanocrystalline diamond films on silicon substrate by microwave plasma chemical vapor deposition has been studied varying the substrate temperature (400, 500, 600, and $700^{\circ}C$), deposition time (0.5, 1, and 2h), and bias voltage (-50, -100, -150, and -200 V) at the microwave power of 1.2 kW, working pressure of 110 torr, and gas ratio of Ar/1%$CH_4$. In the case of low negative bias voltages (-50 and -100 V), the diamond particles were observed to grow to thin film slower than the case without bias. Applying the moderate DC bias is believed to induce the bombardment of energetic carbon and argon ions on the substrate to result in etching the surfaces of growing diamond particles or film. In the case of higher negative voltages (-150 and -200 V), the growth rate of diamond film increased with the increasing DC bias. Applying the higher DC bias increased the number of nucleation sites, and, subsequently, enhanced the film growth rate. Under the -150 V bias, the height (h) of diamond films exhibited an $h=k{\sqrt{t}}$ relationship with deposition time (t), where the growth rate constant (k) showed an Arrhenius relationship with the activation energy of 7.19 kcal/mol. The rate determining step is believed to be the surface diffusion of activated carbon species, but the more subtle theoretical treatment is required for the more precise interpretation.

Effects of rapid thermal annealing on Physical properties of polycrystalline CdTe thin films (급속열처리가 다결정 CdTe 박막의 물성에 미치는 효과에 관한 연구)

  • 조영아;이용혁;윤종구;오경희;염근영;신성호;박광자
    • Journal of the Korean Vacuum Society
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    • v.5 no.4
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    • pp.348-353
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    • 1996
  • Rapid thermal annealing (RTA) was applied to polycrystalline CdTe thin films evaporated on CdS/ITO/glass substrate and the effect of the annealing temperatures and the atmosphere on physical properties of polycrystalline CdTe thin films and CdTe/CdS solar cell characteristics were studied. Results obtained by EDX showed that the bulk composition of CdTe remained stoichiometric after annealing at $550^{\circ}C$ in the air but the surface composition became Cd-rich. Cross-sectional TEM and micro EDX showed that columnar grains and micro-twins remained even after RTA, however, and the sulfur content in the annealed CdTe (added by sulfur diffusion from CdS during the annealing) was much smaller than that by furnace annealing. Among the investigated RTA temperatures and gas environments, the cell made with CdTe annealed at $550^{\circ}C$ in air showed the best solar energy conversion efficiency.

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An experimental study on the performance improvement of dead-end type PEMFC with pulsating effect (맥동 효과를 이용한 dead-end type 연료전지의 성능향상에 대한 실험적 연구)

  • Choi, Jong-Won;Seo, Jeong-Hoon;Hwang, Yong-Sheen;Lee, Dae-Heung;Cha, Suk-Won;Kim, Min-Soo
    • Proceedings of the SAREK Conference
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    • 2008.11a
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    • pp.567-571
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    • 2008
  • PEM Fuel Cell operation mode can be classified into dead-end mode or open mode by whether the outlet port is blocked or not. Generally, dead-end type fuel cell has some merits on the pressure drop and system efficiency because it can generate more power than the open type fuel cell due to high operating pressure condition. However, the periodic purging process should be done for removing water which is formed as product of a reaction in the gas diffusion layer. In this study, cathode side dead-end type operation has been conducted. Moreover, pulsating flow generator at the outlet of cathode side has been suggested for increasing the period to purge the formed water because the pulsating flow can make formed water scattered uniformly over the whole channel. As a result, the purging period with pulsation increased by 1.5-2 times longer than that without pulsating.

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The Theory of Change in Nursing Practice

  • Gas, Du
    • Journal of Korean Academy of Nursing
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    • v.9 no.2
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    • pp.1-6
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    • 1979
  • The topic I have chosen for presentation to you today is entitled, the theory of change in nursing practice or to put it into simpler words. How do new ideas in nursing get started - Where do they come from\ulcorner - How are these ideas spread through the social system of nurses\ulcorner - What makes some Directors of Nursing more ready to accept change than others\ulcorner What factors in-fluence than to introduce change\ulcorner The process of change has been the subject of considerable research in such diverse disciplines and fields as anthropology and rural sociology, marketing and, also, education, for many years. The studies are called“diffusion”studies, or sometimes“adoption”studies, or“adoption of innovation”studies. They deal specifically with the transmission of innovations to members of a social system, and are considered a subset of research in the general field of communication, Although a number of studies have been undertaken in medicine, and, in the past decade, numerous ones in education, there have been few studies on the process of change in nursing. Yet, nursing has undergone tremendous changes in the past 10 years - the nursing process has been introduced, there is the expanded role of the nurse which is rapidly becoming a regular mode of practice - and many, many more changes, We seem to be always running to try. to keep up with changes that have already taken place. Yet little is known about known about the process of change itself - how practitioners learn about new ideas and techniques, or about the factors which influence nurses to accept some changes and reject others. The purpose of the study I am about. to describe was to analyze the process of change as it functioned in regard to nursing innovations in a selected segment of Canadian hospitals, and to relate the analysis to general research and theory about information transmission and the acceptance of change. Three aspects of the process were investigated : 1. The flow of information about changes in nursing practice through a network of hospitals. 2. Factors influencing the adoption of changes in nursing practice. 3. Factors influencing delay in the adoption process, the rejection of changes, or their discontinuance following adoption.

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The interaction between helium flow within supersonic boundary layer and oblique shock waves

  • Kwak, Sang-Hyun;Iwahori, Yoshiki;Igarashi, Sakie;Obata, Sigeo
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2004.03a
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    • pp.75-78
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    • 2004
  • Various jet engines (Turbine engine family and RAM Jet engine) have been developed for high speed aircrafts. but their application to hypersonic flight is restricted by principle problems such as increase of total pressure loss and thermal stress. Therefore, the development of next generation propulsion system for hypersonic aircraft is a very important subject in the aerospace engineering field, SCRAM Jet engine based on a key technology, Supersonic Combustion. is supposed as the best choice for the hypersonic flight. Since Supersonic Combustion requires both rapid ignition and stable flame holding within supersonic air stream, much attention have to be given on the mixing state between air stream and fuel flow. However. the wider diffusion of fuel is expected with less total pressure loss in the supersonic air stream. So. in this study the direction of fuel injection is inclined 30 degree to downstream and the total pressure of jet is controlled for lower penetration height than thickness of boundary layer. Under these flow configuration both streams, fuel and supersonic air stream, would not mix enough. To spread fuel wider into supersonic air an aerodynamic force, baroclinic torque, is adopted. Baroclinic torque is generated by a spatial misalignment between pressure gradient (shock wave plane) and density gradient (mixing layer). A wedge is installed in downstream of injector orifice to induce an oblique shock. The schlieren optical visualization from side transparent wall and the total pressure measurement at exit cross section of combustor estimate how mixing is enhanced by the incidence of shock wave into supersonic boundary layer composed by fuel and air. In this study non-combustionable helium gas is injected with total pressure 0.66㎫ instead of flammable fuel to clarify mixing process. Mach number 1.8. total pressure O.5㎫, total temperature 288K are set up for supersonic air stream.

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Theoretical Model of Coaxial Twin-Fluid Spray In a Liquid Rocket Combustor (연소실 내 동축형 2-유체 분무의 이론적 모델)

  • 조용호;윤웅섭
    • Journal of the Korean Society of Propulsion Engineers
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    • v.6 no.2
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    • pp.37-44
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    • 2002
  • A theoretical study of spray and combustion characteristics due to coaxial twin-fluid injection is conducted to investigate the effects of liquid jet property, droplet size, contact length and liquid jet velocity. Model is properly validated with measurements and shows good agreement. Prediction of jet contact length, droplet size, liquid jet velocity reflects genuine features of coaxial injection in physical and practical aspects. Both the jet contact length and tile droplet size are reduced in a linear manner with an increase of injector diameter. Cross sectional area of liquid intact core is reduced with augmented jet splitting rate, thus the jet is accelerated to maintain the mass continuity and with an assistant of momentum diffusion by burnt gas.

Experimental Investigation of the Water Droplet Dynamics inside the Simulated PEMFC Single Flow Channel with GDL (GDL을 고려한 고분자전해질형 연료전지 모사 단위 유로 채널에서의 물방울 유동 특성에 대한 실험적인 고찰)

  • Kim, Han-Sang;Ji, Yong-Whi;In, Ji-Hyun;An, Ji-Yong
    • Transactions of the Korean hydrogen and new energy society
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    • v.24 no.1
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    • pp.76-83
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    • 2013
  • Polymer electrolyte membrane fuel cells (PEMFCs) are regarded as a promising alternative to replace the existing automotive power sources. To get high performance and long-term durability for PEMFC systems, novel water management is essential. To this end, a comprehensive understanding of dynamics of the liquid water droplets within an operating PEMFC plays an important role. In this work, direct visualization of dynamic behaviors of the water droplet in the ex situ unit flow channel of a PEMFC including gas diffusion layer (GDL) is carried out as one of the fundamental studies for novel water management. Water droplet dynamics such as the movement and growth of liquid water droplets are mainly presented. Effects of GDL characteristics and inlet air flow rate on the water droplet transport and its removal from the flow channel are also discussed. The data obtained in this study can contribute to build up the fundamental operating strategy including balanced water removal capacity for automotive PEMFC systems.

Surface Treatment of Mg95Zn4.3Y0.7 Alloy Powder Consolidates using Plasma Electrolytic Oxidation (플라즈마 전해산화공정을 이용한 Mg95Zn4.3Y0.7 합금분말 성형체의 표면특성제어)

  • Kim, J.H.;Choi, H.S.;Kim, D.H.;Hwang, D.Y.;Kim, H.S.;Kim, T.S.
    • Journal of Powder Materials
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    • v.15 no.2
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    • pp.95-100
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    • 2008
  • The investigation is to modify the mechanical and chemical properties of Mg alloys using a combination of rapid solidification and surface treatment. As the first approach, $Mg_{95}Zn_{4.3}Y_{0.7}$ was gas atomized and pressure sintered by spark plasma sintering process (SPS), showing much finer microstructure and higher strength than the alloys as cast. Further modification was performed by treating the surface of PM Mg specimen using Plasma electrolytic oxidation (PEO) process. During the PEO processing, MgO layer was initiated to form on the surface of Mg powder compacts, and the thickness and the density of MgO layer were varied with the reaction time. The thickening rate became low with the reaction time due to the limited diffusion rate of Mg ions. The surface morphology, corrosion behavior and wear resistance were also discussed.