• 폴리머
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• 제35권3호
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• pp.189-195
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• 2011

조직 형성을 위한 생리학적 환경을 제공하는 새로운 생활성 지지체의 디자인은 생체재료 연구에서 중요한 분야이다. 본 연구에서는 3차원적 실크/PLGA 지지체의 물성평가를 위해 압축강도, 수분친화도, SEM 분석을 하였으며, 세포친화성 평가를 위해 RAW 264.7과 NIH/3T3의 부착, 증식 및 표현형유지와 염증반응에 미치는 영향을 조사하였다. 지지체는 용매 캐스팅/염 추출법으로 제조하였고, 압축강도, 수분친화도 면에서 실크 함량이 20 wt%에서 우수함 확인했으며, 표면의 거침도활 높여 세포부착에 긍정적인 구조임을 확인하였다. 세포친화성 분석 결과 실크함량이 20 wt%인 실크/PLGA 지지체에서 높은 초기부작도 및 증식률을 보였으며, 실크함량이 20 wt%에서 염증반응이 눈에 띄게 감소함을 확인하였다. 조직공학적 응용에 실크/PLGA 지지체가 유용할 것이라 판단하였다.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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• pp.340-343
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• 2008

This work reports the simple fabrication of the single cell gap transflective liquid crystal display (LCD) using wire grid polarizer. The nano sized wire grid polarizer was patterned on common electrode itself, on the reflective part of FFS (Fringe field switching) mode whereas the common electrode was unpatterned at transmissive part. However, this structure didn't show single gamma curve, so we further improved the device by patterning the common electrode at transmissive part. As a result, V-T curve of proposed structure shows single gamma curve. Such a device structure is free from in-cell retarder, compensation film and reflector and furthermore it is very thin and easy to fabricate.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2009년도 춘계학술발표대회
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• pp.278-281
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• 2009

KSTAR(Korea Superconducting Tokamak Advanced Research)는 고성능 플라즈마 연구를 위한 대형 연구실험 장치이다. 이러한 거대 장치에는 많은 시스템이 분산되어 연결되어 있으며 그 구조 역시 매우 복잡하여 시스템간의 인터페이스에 많은 제약과 어려움이 따른다. 이러한 복잡하고 다양한 시스템을 통합하고 여기서 발생하는 여러 종류의 데이터를 획득하기 위해서 KSTAR는 EPICS(Experimental Physics and Industrial Control System)라는 오픈소스 기반의 분산 제어용 미들웨어를 구축하였고 이를 기반으로 KSTAR 통합 제어 시스템을 개발 하였다. 2008년 KSTAR 최초 플라즈마 실험 기간 동안의 운전을 통해 EPICS 미들웨어와 EPICS channel archiver를 이용하여 다양한 24시간 연속 운전데이터를 안정적으로 저장하고 추출할 수 있음을 확인하였다. 논문에서는 시스템의 구축 방법 및 운전결과에 대해 기술하고자 한다.

• 센서학회지
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• 제28권2호
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• pp.88-93
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• 2019

This paper is concerned with distributed fusion moving average prediction for continuous-time linear stochastic systems with multiple sensors. A distributed fusion with the weighted sum structure is applied to the optimal local moving average predictors. The distributed fusion prediction algorithm represents the optimal linear fusion by weighting matrices under the minimum mean square criterion. The derivation of equations for error cross-covariances between the local predictors is the key of this paper. Example demonstrates effectiveness of the distributed fusion moving average predictor.

• Current Optics and Photonics
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• 제6권4호
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• pp.381-391
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• 2022

Two-photon-polymerization additive-manufacturing systems feature high resolution and precision. However, there are few reports on specific methods and possible problems concerning the use of small lasers to independently build such platforms. In this paper, a femtosecond-laser two-photon-polymerization additive-manufacturing system containing an optical unit, control unit, monitoring unit, and testing unit is built using a miniature femtosecond laser, with a detailed building process and corresponding control software that is developed independently. This system has integrated functions of light-spot detection, interface searching, micro-/nanomanufacturing, and performance testing. In addition, possible problems in the processes of platform establishment, resin preparation, and actual polymerization for two-photon-polymerization additive manufacturing are explained specifically, and the causes of these problems analyzed. Moreover, the impacts of different power levels and scanning speeds on the degree of polymerization are compared, and the influence of the magnification of the object lens on the linewidth is analyzed in detail. A qualitative analysis model is established, and the concepts of the threshold broadening and focus narrowing effects are proposed, with their influences and cooperative relation discussed. Besides, a linear structure with micrometer accuracy is manufactured at the millimeter scale.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.1015-1016
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• 2005

• Bulletin of the Korean Chemical Society
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• 제30권12호
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• pp.3137-3140
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• 2009

• 한국진공학회:학술대회논문집
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• 한국진공학회 2006년도 제31회 학술논문발표회 초록집
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• pp.217-217
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• 2006

• BMB Reports
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• 제49권6호
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• pp.303-304
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• 2016

Myoblast fusion is important for skeletal muscle formation. Even though the knowledge of myoblast fusion mechanism has accumulated over the years, the initial signal of fusion is yet to be elucidated. Our study reveals the novel function of a phosphatidylserine (PS) receptor, stabilin-2 (Stab2), in the modulation of myoblast fusion, through the recognition of PS exposed on myoblasts. During differentiation of myoblasts, Stab2 expression is higher than other PS receptors and is controlled by calcineurin/NFAT signaling on myoblasts. The forced expression of Stab2 results in an increase in myoblast fusion; genetic ablation of Stab2 in mice causes a reduction in muscle size, as a result of impaired myoblast fusion. After muscle injury, muscle regeneration is impaired in Stab2-deficient mice, resulting in small myofibers with fewer nuclei, which is due to reduction of fusion rather than defection of myoblast differentiation. The fusion-promoting role of Stab2 is dependent on its PS-binding motif, and the blocking of PS-Stab2 binding impairs cell-cell fusion on myoblasts. Given our previous finding that Stab2 recognizes PS exposed on apoptotic cells for sensing as an "eat-me" signal, we propose that PS-Stab2 binding is required for sensing of a "fuse-me" signal as the initial signal of myoblast fusion.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2009년도 하계학술대회 논문집
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• pp.39-40
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• 2009

The patterned vertical alignment (PVA) display showed good electro-optic properties such as wide viewing angle, fast response time, high Contrast Ratio. However, the device has patterned electrode on both top and bottom electrodes which requires high accuracy of assembling of top and bottom substrates in order to exhibit a high performance. So, they have disadvantage about low yield. In order to resolve these problem, in this paper, we studied about top substrate pattern free vertical alignment device associated with surface polymer stabilization using the UV curable monomer. This method shows simple progress, low cost and good electro-optic properties such as high transmittance and fast response time.