• BMB Reports
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• 제40권2호
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• pp.270-276
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• 2007

We have cloned a novel mouse zinc finger protein gene Znf313 by rapid amplification of cDNA ends (RACE) according to the homologue of human ZNF313 gene. The cDNA is 2,163 base pairs (bp) in length and encodes a 229 amino acids (aa) protein with a $C_3HC_4$ ring finger domain and three $C_2H_2$ domains. 89% and 93% nucleotide (nt) and aa sequence identity is observed with its human homologue. Revealed by Northern blot and RT-PCR, full mRNA consists of 2.16 kb and widely expresses in tissues as a single transcript, most abundantly in heart, liver, kidney and testis. The expression of Znf313 in testis is detected in all development stages. Western blot analysis also reveals that Znf313 is expressed in the tissues. Immunohistochemical staining and subcellular localization demonstrate that Znf313 is expressed both in the cytoplasm and nucleus whereas predominantly localized in the nucleus. Present data suggests that Znf313 gene might play a fundamental role in gene transcription and regulation in organism and relates to spermatogenesis.

• 비파괴검사학회지
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• 제35권1호
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• pp.18-24
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• 2015

철도 시설물의 상태를 종합적으로 동시에 검측하고 건전성 평가가 가능한 고속 종합검측시스템을 위해 열차의 위치검지 정보는 필수불가결하다. 본 논문에서는 위치검지를 위한 위치 기술중 관성센서의 측정과 분석에 대해 다룬다. 관성센서의 가속도 정보와 각속도 정보에 대해 진폭과 주파수 관점에서 분석하였고, 진동 및 열차 동역학에 대한 검토도 이루어졌다. 이러한 검토 결과와 GPS 정보를 이용하여 호남선 나주역부터 일로역까지 한국형 틸팅열차의 위치검지를 수행하였다. 이와 같은 센서 측정치와 열차의 거동에 대한 동기화된 분석은 열차위치검지 시스템의 설계와 성능 향상에 도움을 줄 수 있다.

• 한국한의학연구원논문집
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• 제12권3호통권18호
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• pp.1-15
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• 2006

최근 수년간 한국어를 위한 어휘의미망에 대한 관심은 꾸준히 높아지고 있지만, 그 결과물을 어떻게 평가하고 활용할 것인가에 대한 방안은 이루어지지 않고 있다. 본 논문에서는 단어클러스터링 시스템 개발을 통하여, 어휘의미망에 의해 확장되기 전후의 클러스터링을 수행하여 데이터를 서로 비교하였다. 단어클러스터링 시스템 개발을 위해 사용된 학습 데이터는 신문 말뭉치 기사로 총 68,455,856 어절 규모이며, 특성벡터와 벡터공간모델을 이용하여 시스템A를 완성하였다. 시스템B는 구축된 '[-하]동사류' 3,656개의 어휘의미를 포함하는 동사 어휘의미망을 활용하여 확장된 것으로 확장대상정보를 선택하여 특성벡터를 재구성한다. 대상이 되는 실험 데이터는 '다국어 어휘의미망-코어넷'으로 클러스터링 결과 나타난 어휘의 세 번째 층위까지의 노드 동일성 여부로 정확률을 검수하였다. 같은 환경에서 시스템A와 시스템B를 비교한 결과 단어클러스터링의 정확률이 45.3%에서 46.6%로의 향상을 보였다. 향후 연구는 어휘의미망을 활용하여 좀 더 다양한 시스템에 체계적이고 폭넓은 평가를 통해 전산시스템의 향상은 물론, 연구되고 있는 많은 어휘의미망에 의미 있는 평가 방안을 확대시켜 나가야 할 것이다.

• Archives of Plastic Surgery
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• 제43권2호
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• pp.145-152
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• 2016

Background Innovation has molded the current landscape of plastic surgery. However, documentation of this process only exists scattered throughout the literature as individual articles. The few attempts made to profile innovation in plastic surgery have been narrative, and therefore qualitative and inherently biased. Through the implementation of a novel innovation metric, this work aims to identify and characterise the most prevalent innovations in plastic surgery over the last 50 years. Methods Patents and publications related to plastic surgery (1960 to 2010) were retrieved from patent and MEDLINE databases, respectively. The most active patent codes were identified and grouped into technology areas, which were subsequently plotted graphically against publication data. Expert-derived technologies outside of the top performing patents areas were additionally explored. Results Between 1960 and 2010, 4,651 patents and 43,118 publications related to plastic surgery were identified. The most active patent codes were grouped under reconstructive prostheses, implants, instruments, non-invasive techniques, and tissue engineering. Of these areas and other expert-derived technologies, those currently undergoing growth include surgical instruments, implants, non-invasive practices, transplantation and breast surgery. Innovations related to microvascular surgery, liposuction, tissue engineering, lasers and prostheses have all plateaued. Conclusions The application of a novel metric for evaluating innovation quantitatively outlines the natural history of technologies fundamental to the evolution of plastic surgery. Analysis of current innovation trends provides some insight into which technology domains are the most active.

• 한국한의학연구원논문집
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• 제12권2호통권17호
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• pp.47-62
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• 2006

This research is intended to analyze the necessity of the integrated organization for the performance in order to the extension of scale and the systematic promotion concerning to the Korean medicine informational project, and to research the promotional method of Korean Medicine information through the constitution of organization for preparing the informational basic. There are three main important subjects to be done in this research project. The initial issue is to devise a comprehensive and systematic plan of Korean medicine information according to the Korean Medicine Rearing Raw('03. 8). Furthermore, it is necessary to reinforce the integrated informational ability of Organizations concerning to the Korean Medicine. Finally, with the above works accomplished, the overall standard of Korean Medicine Information should be settled. Initially, we compose an advisory committee of the Korean Medicine Information in the first year. The members of the committee include the informational coordinates of related government agencies, the experts in Korean Medicine Information, and specialists in the domains of computer science and information. In the next phase, we derive the promotional strategy for 'Center for Korean Medicine Information'. In other words, by means of analyzing the current issues and outstanding problems of on-going research projects and environments, the ultimate directions of the whole activities are established. Also, we build the medium and long-range road map of Korean Medicine Information Research by setting strategy for the policy projects related to the area. With the various research activities in this project, we can achieve the following practical strategic benefits. Firstly, we can lay a foundation for the Korean Medicine Information by establishing the fundamental plan for 'Korean Medicine Information Center'. Secondly, information strategic projects about 'Korean Medicine Information Center'. Secondly information strategic projects about 'Korean Medicine Information Development' can be performed in more systematic fashion and promoted by stages. Finally, by confirming the contents of the Korean Medicine of KMS system, we invent an opportunity of new project in the field of the Korean Medicine Information by means of practicing and managing the 'korean Medicine Information Custom Service'.

• 한국융합학회논문지
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• 제9권1호
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• pp.405-418
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• 2018

본 논문은 자유학기제 진로탐색을 위한 기초 자료 제공의 차원에서 시행되었다. 진로교육의 목적을 전문가 양성에 두고 전문가 수행 요건에 대한 선행 연구 결과들을 기초로 진로탐색을 위한 구체적인 접근 방법을 도출하려 하였으나 전문가 수행 요건에 대한 논쟁들이 해결이 되지 않고 있는 상황이어서 전문성 핵심 요소들을 인간의 다양한 인지 현상들이 형성되어 나오는 근원적 인지 메커니즘을 통해 전체적으로 확인하였다. 그 결과 전문가 영역은 내용 전문성과 표현 전문성으로 구분되는데 내용과 표현이 다양한 통합 비율로 결합되어 있는 전문성과 내용이나 표현이 독립적으로 구성된 전문성으로 다시 다양하게 구분되며, 각 영역에 따라 전문가 수행에 요구되는 조건들이 다양하다. 한편 분야 최고 전문가는 지능, 내적사고, 호기심, 집착력 등의 수준이 특정 전문성이 요구하는 수준과 일치될 때 탄생할 수 있고, 특히 집착력이 결정적 역할을 하는 것으로 나타났다. 본 논문은 이런 결과를 바탕으로 전문성과 관련된 쟁점들에 대해 논의하고 자유학기제 진로 탐색을 위한 구체적인 접근법을 제공하고 있다.

• 디지털융복합연구
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• 제10권4호
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• pp.297-308
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• 2012

본 연구는 녹색건강사업 인재양성센터에서 추후 의료 관광업계 종사자가 될 인재교육을 받고 있는 학생그룹(106명)과 녹색건강산업 시장의 수요예측을 위해서 강원도 의료기관 및 관광관련업체에 종사하는 그룹(84명)을 대상으로 하여 2010.11.5 -11. 19까지 설문조사 및 심층인터뷰를 실시하였다. 녹색건강산업이라는 새로운 산업에 대한 생소한 용어에 대해서도 인지도가 낮으므로 지자체의 특성에 따른 의료관광산업에 대한 용어의 정의 및 핵심사업의 구체적인 정보를 공유할 수 있는 시스템 구축이 필요하다. 따라서 녹색건강산업 핵심인력을 1단계로 대학 중심으로 양성할 필요성이 있고, 2단계로, 기존 전문인력 대상으로 의료관광 특화인력을 재교육하여 양성할 수 있도록 정책적 지원도 활성화 되어야 한다.

• Perspectives in Nursing Science
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• 제9권2호
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• pp.127-135
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• 2012

Purpose: The purpose of this study was to investigate the academic achievements, satisfaction and educational demands of nursing students at a college of nursing. Methods: The study subjects consisted of 134 senior nursing students who completed their clinical practicums. The students were asked to complete the evaluation survey for the curriculum. The evaluation survey for the curriculum consisted of three parts: 1) academic achievements of educational objectives, care of subjects, and skills; 2) satisfaction with the curriculum, clinical practice environment, and educational environment; 3) demands on the curriculum and clinical practicum. Results: The mean scores on the achievement levels of educational objectives, care of subjects and skills of the students were $3.68{\pm}0.53$, $3.69{\pm}0.59$, and $3.77{\pm}0.56$, respectively. The low rated domains were 'understanding and delivering culturally competent nursing' and 'competence in fundamental nursing skills' in their levels of achievements. Overall, students were satisfied with the nursing curriculum and educational environment. However, their satisfaction scores for the hours and arrangements of the clinical practicum, and the ratios and arrangements of lectures and clinical practicum were relatively low. Conclusion: The findings of this study are important to redesign nursing curriculum in order to prepare graduates for rapidly changing health care environments. We need to try various strategies to improve the clinical competencies of students by designing a curriculum based on social change and student needs.

• 가정∙방문간호학회지
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• 제16권1호
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• pp.49-58
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• 2009

Purpose: This study aimed to clarify the needs for hospital-based home care nursing medical services in elder care institutions by analyzing the details and frequency of medical services provided by, and the needs for, hospital based home care nursing in select institutions in Korea. Methods: Seventy-seven staffs at elderly care institutions located throughout the country completed self-report questionnaires between February 1 and May 31, 2009. SPSS ver. 14.0 was used for data analysis regarding frequency and percentage, mean and standard deviation. Results: Forty-eight hospital-based home care nursing medical services in eight domains were identified as being needed in elderly care institutions. The most commonly used medical services were providing instruction in oral drug administration, checking drug beneficial/adverse effects, and administering blood glucose test, while the most needed medical services requiring hospital based home care nursing were complex pressure ulcer care, followed by diabetic foot ulcer management and nutrient injection. Conclusion: The present results should provide fundamental data for better healthcare services with hospital based home care nursing at elderly care institutions as part of a 'win-win' strategy through which medical expenses are reduced, insurance costs are kept stable, and safe and high-quality medical services are provided for residents of elder care institutions. Political decisions intended to promote visits by hospital based home care nurses to elder care institutions would be a prudent course.

• 보건교육건강증진학회지
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• 제19권3호
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• pp.121-133
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• 2002

The purpose of this study was to set up the basic model to monitor the health status of the middle and high school students in the adolescent period, as well as to provide the fundamental data which might serve as the new standards for their better health maintenance and promotion. The collected data comprised the characteristics of the subjects in the three different fields of life such as school, family and everyday, which could affect their physical fatigues, and they were analyzed to determine the factors of significant influence upon their physical fatigues and to reveal their relativity. A total of 5,954 students at 6 boys' and girls' middle and high schools in Taejon City completed self-administered questionnaires(to measure Health Practice Index and others) asking about each of three life domains during the period March through June, 2000. The key study results were as follows; 1. The middle school students showed more subjective symptoms of fatigue which may be a marker reflecting physical health status, than the high school students. The higher scores were associated, based on school life, with the groups who were boys, who were in lower school grades, who achieved better academic performances and had better relationship with friends. 2. As for family life, the higher scores were in the groups whose financial conditions were better, whose parents showed more interest to their children, whose sense of satisfaction with family life was higher, and whose health status was better. 3. As for life styles, the individuals showed the higher scores in the groups who had breakfasts daily, who didn't have inter-meal snacks, who took regular exercises, who didn't smoke and drink than, their counterparts. 4. The higher level of fatigue was associated with the groups whose health conditions were good, who are satisfied with school life, who were boys rather than girls, who are satisfied with family life, who didn't have inter-meal snacks, who were in good relationship with friends, who achieved greater academic performances, who took regular exercises, who didn't smoke, and whose parents showed more interest in their children.