• Journal of Korean Dental Science
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• v.4 no.1
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• pp.6-13
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• 2011

Purpose: Craniosynostosis (CS), one of the most common congenital craniofacial deformities, is the premature closure of cranial sutures. NELL-1 is a novel molecule overexpressed during premature cranial suture closure in human CS. From a functional perspective, NELL-1 has been reported to accelerate chondrocyte maturation and modulate calvarial osteoblast differentiation and apoptosis pathways. The mechanism through which NELL-1 induces these phenomena, however, remains unclear. The purpose of this study is to identify the NELL-1 binding protein(s) through which the biologic mechanism of NELL-1 can be further investigated. Materials and Methods: Far-Western and Immunoprecipitation (IP) assays were performed, independently and in sequence, followed by mass spectrometry to identify the NELL-1 binding proteins. Reverse IP was used to verify and confirm candidate binding protein. Results: The only confirmative protein from current experimentation was vimentin. Vimentin is the major structural component of the intermediate filaments. Conclusion: The present study identified and confirmed vimentin as a NELL-1 binding protein, which opened up a new window to mechanistically facilitate studies on this CS-associated molecule.

• The Research Journal of the Costume Culture
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• v.20 no.5
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• pp.635-654
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• 2012

This paper studied sports-inspired fashion(SIF) that is often characterized as 'designer clothes inspired by active sportswear.' First, we reviewed the social, economical, artistic, and technological background behind its development. Second, we studied the development history of SIF by classifying it into four periods. Third, we analyzed how SIF emerged and developed with its own characteristics from a historical perspective. For a theoretical background, we did a critical review of previous literature in the field of clothing history, history of culture, and art history. We collected the data from magazines, such as Fashion Show and Gap Press and from the internet sources as well, such as firstviewkorea.com. We also did the content analysis of the data by consulting a chosen group of fashion designers. This study revealed that active sportswear started to develop from everyday clothes for functional convenience in the beginning and then SIF emerged later as a major fashion trend with the popularity of sportive look. This trend became stronger with the global spread of American popular culture. SIF eventually became high fashion with collaboration between sportswear industry and designers. This study confirmed that SIF reflects the characteristics of many sports games in silhouettes, colors, and details. It is predicted that sports will continue to be an important source of inspiration for fashion designers.

• Journal of Information Processing Systems
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• v.12 no.1
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• pp.1-34
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• 2016

Gene identification is at the center of genomic studies. Although the first phase of the Encyclopedia of DNA Elements (ENCODE) project has been claimed to be complete, the annotation of the functional elements is far from being so. Computational methods in gene identification continue to play important roles in this area and other relevant issues. So far, a lot of work has been performed on this area, and a plethora of computational methods and avenues have been developed. Many review papers have summarized these methods and other related work. However, most of them focus on the methodologies from a particular aspect or perspective. Different from these existing bodies of research, this paper aims to comprehensively summarize the mainstream computational methods in gene identification and tries to provide a short but concise technical reference for future studies. Moreover, this review sheds light on the emerging trends and cutting-edge techniques that are believed to be capable of leading the research on this field in the future.

• Journal of the Korean Society of Costume
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• v.40
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• pp.137-147
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• 1998

Fahion as the form construction of decon-structivistic architecture was analyzed by dividing it into the intrinsic aspect and the formal aspect through an introduction of three characteristic architectural principles into fashion. Intrinsic deconstructivistic fashion as the construction of architectural form has the mixurte of genders both in a form of transvestic and in a form of genderless look as dualism, and can be characterized by pluralistic nationlism with the emergence of the Third World alienated from the international society, and so forth. Difference and the prefixes of dis-and de- are schizophrenic mystic illusionism, chance effect and the differance of space and time and is supporting Jacques Derrida's chiasmus that is the perspective of collage in painting and the multiple observation of collage in painting and the multiple observation point as the play of borrowing the surrealistic technique. The formal construction of deconstructivistic fashion the construction of architectural form has intertextuality material, hybridization of items and the blending of modes and another sphere. Trace as icon deconstrucion attains historical analysis. Dis and de in fashion are showing the retrogre-ssion of gravity through decomposition, decon-tinuity and disjunction emerge nonstructural silho-uette, juxtaposition, inversion and replace- ment of underwear and outer garments. Their decentring expression emerged as construction through mixture and repetition as well as overlapping of planes or spaces. And their disjuctive representation appeared in the form of mutual juxtaposition and substitution with the double-side of formal construction in functional terms.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.3
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• pp.1444-1451
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• 2011

The purpose of this paper is to provide an understanding of building systems and to propose methods of building system analysis and integration. Building components are classified into four major systems; structure, mechanical, envelope, and interior system. There are 11 combinations between major systems. Three integration modes(physical, visual, and functional integration) and 12 integration strategies are proposed. A case study of Richards Medical Research Buildings designed by Louis I. Kahn was conducted from the perspective of building system analysis and integration.

• Journal of Korean Institute of Industrial Engineers
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• v.25 no.1
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• pp.100-110
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• 1999

The objectives of this study are twofold: (1) to evaluate the cockpit of three Korean air force fighters such as F-4, F-5, and F-16 in an ergonomic perspective and (2) to measure the musculoskeletal discomfort of the fighter pilots. For the study, 369 air force pilots from 7 squadrons were surveyed. The study shows that the cockpit design of F-16 is superior to the others. However, F-4 is the worst among them. Statistical analyses reveal that the seat in the cockpit raised the most complaints, regardless of types of fighter planes. The main problems with the seat included inappropriate designs of the backrest angle, seat cushioning, and parachute harness. Also frequently cited are various control switches, control stick, rudder pedal, and the throttle. That these items lack human integration is found in remote positions and improper dimensions. The implications of these findings are discussed. The self-reported musculoskeletal complaints show that the main discomfort is on the back and neck. Also, the buttocks, shoulders, and the legs/knees are common sites of discomfort. A stepwise regression analysis shows that the back discomfort, is mainly caused by the use of the seat, rudder pedal, control stick, and switches. A Spearman rank correlation coefficient test also reveals that job dissatisfaction of the pilots is related to the complaints with the cockpit and musculoskeletal discomfort. These findings suggest that more comprehensive studies for cockpit design in the aspects of functional anthropometry of Korean pilots are needed to reduce the musculoskeletal discomfort.

• Journal of Korean Institute of Industrial Engineers
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• v.25 no.1
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• pp.87-99
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• 1999

A shop floor control system(SFCS) performs the production activities required to fill orders. In order to effectively control these activities, the autonomous agent-based heterarchical shop floor control architecture is adopted where a supervisor does not exist. In this paper, we define functional perspective of the heterarchical shop floor control using planning, scheduling, and execution modules. In particular, we focus on an execution module that can coordinate the planning and scheduling modules and a general execution module that easily can be modified to execute the other equipment. The execution module can be defined informally as a module that downloads and performs a set of scheduled tasks. The execution module is also responsible for identifying and resolving various errors whether they come from hardware or software. The purpose of this research is to identify all the execution activities and solving techniques under the assumptions of the heterarchical control architecture. And we model the execution module in object-oriented modelling technique for generalization. The execution module modeled in object-oriented concept can be adopted to the other execution module easily. This paper also proposes a classification scheme for execution activities of the heterarchical control architecture. Petri-nets are used as a unified framework for modeling and controlling execution activities. For solving the nonexistence of a supervisor, a negotiation-based solution technique is utilized.

• Korean Institute of Interior Design Journal
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• v.24 no.4
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• pp.135-142
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• 2015

The goals of healthcare design based on the human rights to manage physically, psychologically, and emotionally healthy life. The healthcare designs, however, have been criticized not to reflect their primary users, patients' and families' needs, under the management strategy centered by the functional efficiency. The study focused on the patients' room design on the users' perspective. The design criteria for the patients' room in Japan, Germany, Australia, U.S. and Korea were examined and compared. The subjects of analysis are the floor plans of general hospital recently planned and built in Korea and Japan and the standard floor plan models proposed by prior studies in Korea and AusHFG in Australia. Results and conclusions are as follows: (1) the patients' room has developed as a place where the users manage their living during inpatient period and has become a private room. (2) The guidelines for patients' room size in Korea and Japan are not enough considering the users' diverse activities compare to those in U.S. and Australia. (3) The guidelines of Korea should be reconsidered for the users' comfortable lives. It must include the specific criteria of the enough space between beds, the storages, and other assistant tools and facilities. (4) The desirable types of patients' rooms by the numbers of users in Korea are proposed as a one-bed room type and a four-bed room type.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1995.04a
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• pp.193-200
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• 1995

A shop floor control system(SFCS), a central part of agile manufacturing, performs the production activities required to fill orders. In order to effectively control these activities, CSCW (computer supported cooperative work) is adopted where a supervisor does not exist. In this paper, we define functional perspective of CSCW-based shop floor control using planning, scheduling, and execution functions. In particular, we focus on an execution model that can coordinate the planning and scheduling functions. Execution can be defined informally as a function that downloads and performs a set of scheduled tasks. Execution is also responsible for identifying and resolving various errors whether they come from hardware or software. The purpose of this research is to identify all the execution activities and solving techniques under the assumptions of CSCW-based heterarchical control architecture. This paper also proposes a classification scheme for execution activities of CSCW-based heterarchical control architecture. Petri-nets are used as a unified framework for modeling and controlling execution activities. For solving the nonexistence of a supervisor, A negotiation-based solution technique is utilized.

• Journal of Korean Library and Information Science Society
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• v.46 no.4
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• pp.139-159
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• 2015

With advancement of information technology and accumulation of digital resources, the demand on collaboration among libraries, museums and repositories are increasing. The purpose of this study is to propose Korean literature houses as an example of larchiveum. This study explored data management, exhibits and programs of Korean literature house.