• Title/Summary/Keyword: functional mobility

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Investigation of Isomerism in Anthracene-Isothiouronium Salts and Application of these Salts for Anion Sensing

  • Nguyen, Quynh Pham Bao;Kim, Jae-Nyoung;Kim, Taek-Hyeon
    • Bulletin of the Korean Chemical Society
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    • v.30 no.9
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    • pp.2093-2097
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    • 2009
  • Novel fluorescent anion chemosensors based on anthracene-isothiouronium derivatives were synthesized. Isomerism due to the intramolecular mobility in these isothiouronium salts was detected by $^1H$ NMR spectroscopy. The effect of the substituent, temperature and solvent on the isomerism was also examined. The anthracene-isothiouronium sensor showed significant fluorescent enhancement upon the addition of various anions such as fluoride, acetate, and dihydrogen phosphate, even in the presence of water.

Performance of Activities of Daily Living in Adult Hemiplegic Patients (성인 편마비 환자의 일상생활동작 수행능력 평가)

  • Kim, Sang-Su;Kwon, Mi-Ji
    • Journal of Korean Physical Therapy Science
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    • v.2 no.3
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    • pp.645-651
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    • 1995
  • The purpose of study was that the functional gains achieved by stroke patients after rehabilitation in the acute phase have been documented. Sixty stroke inpatients who were at least 3.57 month postonset participated;32 males and 28 females;mean age, 57.4 years. By the classification of diagnosis, 20 subjects were cerebral infarction and 27 subjects were cerebral hemorrhage. Activities of daily living(ADL) performance was investigated using the Klein-Bell ADL Scale. ADL test was practiced within physical therapy room. The outcome variables were first analyzed using frequency statistics. The functional gains of the patients with sex and hemiplegic site were then using an ANOVA. Mean score of dressing, elimination, mobility, bathing/hygiene, eating, and telephone use, 26.6, 56.0, 41.4, 36.5, 82.0, and 56.7. Mean score of total, 43.0. There was no significant difference in sex and hemiplegic site.

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Interactions of Membrane and PMAP-23 Studied by $^{31}P$ solid-state NMR Spectroscopy

  • Kim, Si-Won;Kim, Suhk-Mann
    • Journal of the Korean Magnetic Resonance Society
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    • v.11 no.2
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    • pp.110-114
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    • 2007
  • [ $^{31}P$ ] powder pattern spectra were measured to investigate the aspects of the interaction between the MLV (Multilamellar vesicle) and PMAP-23, a membrane of cathelicidin family and then CSAs(chemical shift anisotropy) were calculated to indentify the extent of perturbation of phospholipid mobility by the peptides. We found that acidic phospholipid interacts strongly with PMAP-23, and the analogues which modified to increase the amphipathic property showed that larger change of CSA. The analogue which introduced positive charge showed the same effects with amphipathic property.

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Functional Analysis of RAD4 Gene Required for Nucleotide Excision Repair of UV-induced DNA Damage in Saccharomyces cerevisiae

  • Park, Sang Dai;Park, In Soon
    • Animal cells and systems
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    • v.6 no.4
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    • pp.311-315
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    • 2002
  • The RAD4 gene is essential for nucleotide excision repair in Saccharomyces cerevisiae. It has been known that the deduced amino acid sequence of Rad4 protein contains three DNA-dependent ATPase/helicase motifs. To determine the biochemical activities and functional role of RAD4 the Rad4 protein was expressed and purified. Immunoblot analysis showed a specific band of 21 kDa, which was well-matched with the size of open reading frame of the RAD4 gene. The purified Rad4 protein had no detectable helicase activity. However, the protein could interact with double stranded oligonucleotides, as judged by mobility shift assay. This result suggests that the Rad4 protein is a DNA binding protein.

Functional Disorders of the Temporomandibular Joint and the Masticatory System - Distribution of Symptoms and Symptoms in Relation to Impaired Mobility of the Mandible - (악관절 및 저작계 기능장애에 관한 연구)

  • 정성창;임용한
    • Journal of Oral Medicine and Pain
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    • v.7 no.1
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    • pp.32-40
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    • 1982
  • Functional disorders of the temporomamdibular joint and masticatory system were investigated in 209 men and 110 women, ranging form 20 to 30 years old, with a method devised by Agerberg and Carlsson. The investigated persons were dental students of the School of Dentistry, Seoul National University and student nurses of the School of Medicine, Seoul National University. The obtained results were as follows : 1. Facial pain and headache were reported by 32%. 2. Pain on gaping was localized mainly to the temporomandibular area and was noted in 8%. 3. Chicking of the temporomandibular joints was reported by 26%, somewhat more often by males. 4. Clenching of the teeth was relatively common in men and biting of the lip was comman in women. 5. Prevalence of mandibular dysfunction was found in 53%.

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Dynamic Upper Eyelid Reconstruction for Total Periorbital Soft Tissue Loss

  • Vathulya, Madhubari;Manohar, Nishank;Jagtap, Manish Pradip;Mago, Vishal;Jayaprakash, Praveen A.
    • Archives of Plastic Surgery
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    • v.49 no.3
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    • pp.319-323
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    • 2022
  • Total eyelid defect comprises full-thickness loss of both upper and lower eyelids in a patient. It is a rare and devastating condition with serious implications related to vision, which mandates early and functional reconstruction when associated with intact globe. The primary goal is to give a stable coverage for orbital protection but at the same time provide a functional reconstruction of the defect, to allow for adequate mobility of the eyelids so that the patient's vision is restored to normal with minimal disability. When the defect is massive, and in the absence of loco-regional flaps, microvascular tissue transfer is needed. In this report we describe a radial-artery-based microvascular tissue transfer with a unique innovation utilizing the contralateral frontalis muscle to reconstruct a case of unilateral total upper and lower eyelid loss.

Balance Training Program for Community-Dwelling Elders with Risk of Falls: A Multi-center Randomized Controlled Trial

  • Yang Rae Kim
    • Physical Therapy Rehabilitation Science
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    • v.12 no.2
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    • pp.192-200
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    • 2023
  • Objective: This study aimed to assess the effectiveness of a balance training program in improving balance and functional independence to reduce fall risks among community-dwelling elders. Design: A multi-center randomized controlled trial Methods: A total of 66participants were randomly assigned to a balance training group or a control group. The balance training program, conducted three times a week for 32 weeks, included warm-up exercises, main balance training exercises, and cooldown stretch exercises. Outcome measures included the Berg Balance Scale (BBS), Timed Up and Go Test (TUGT), and Modified Barthel Index (MBI). Results: The balance training group demonstrated significant improvements in all outcome measures, indicating enhanced balance, improved functional mobility, and increased independence in activities of daily living. In contrast, the control group showed only slight improvements in BBS, TUGT and MBI scores. Conclusions: These findings provide evidence supporting the effectiveness of balance training programs in reducing fall risk and promoting health and wellbeing among community-dwelling elders. Future research should aim to refine the design of these programs and assess the sustainability of the observed improvements.

The Effect of Prism Adaptation Following Traumatic Brain Injury: A case report

  • Jeong, Eun-Hwa;Min, Yoo-Seon
    • Therapeutic Science for Rehabilitation
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    • v.6 no.2
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    • pp.37-45
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    • 2017
  • Background: The presence of visuospatial impairment can make patients slow functional recovery and impede the rehabilitation process in TBI patients. Objective: The aim of this study is to investigate effects of prism adaptation treatment for functional outcomes in patients following traumatic brain injury. Methods: The subject received prism adaptation treatment for 2 weeks additionally during traditional rehabilitation for 4 weeks. The Patient has prism adaptation treatment while wearing wedge prisms that shift the external environment about $12^{\circ}$ leftward. The patient received 10 sessions, 15-20min each session. Outcome measures were visuospatial deficit(line bisection, latter cancellation), Visual and spatial perception(LOTCA-visual perception and spatial perception), motor function of upper extremity(FMA U/E; Fugl-Meyer motor assessment upper extremity, ARAT; Action research arm test), balance(BBS; Berg Balance Scale), mobility(FAC; Functional ambulation classification) and functional level(FIM; Functional independent measure). All Assessments took place on study entry and post-treatment assessments were performed at discharge from the hospital. Results: After prism adaptation, the visuospatial impairment scores improved as indicated in the line bisection(-15.2 to -6.02), latter cancellation(2 to 0) and LOTCA- spatial perception scores(7 to 9). The upper motor function improved as indicated in the scores of affected FMA U/E(21 to 40) and ARAT(4 to 22). Ambulation and balance improved as indicated in the BBS scores(25 to 38) and FAC scores(0 to 4). ADL function improved as indicated in the FIM total scores 54 to 70(motor 34 to 61, cognition 20 to 29). Conclusion: Prism adaptation did improve functional level such as motor functions and ADL abilities in TBI patient. Further research is recommended.

Multi-Functional Furniture Design in Small Living Space

  • Kim, Hyun-Jeong;Choi, Kyung-Ran;Sung, Yun-Jung
    • Journal of the Korea Furniture Society
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    • v.22 no.3
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    • pp.190-198
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    • 2011
  • This study intended to present a new direction of differentiated and innovative furniture design for small living space overcoming the uniformity of conventional small living. In order to achieve these goals, a new piece of furniture with multi functions useful for such small space has been designed and explained in this study. This new type multi-functional furniture can be utilized as kitchen, dining table, home bar or office stand depending on the user's necessity. In particular, it provides more adaptability to changing life and spatial availabilities for small living space in terms of space division, separation and fusion features. Based on the needs of small living space brought by social changes, the conventional concept of small living space, which divides space by partitions or walls, should be changed into flexible perception of space. Also, this research proposed the features of furniture design for functional shifts in terms of its functional, structural, and systematical aspects. In this respect, space can be regarded as a variable place and the image of space can be differently appreciated by means of shift, functional transition and mobility. That is, small living space can be perceived as kitchen, living space or working space at the same time. In conclusion, the versatile use of limited space can be a solution to the issues related to small living space; the convertible and movable furniture called F4 Island presented in this study can transform such spatially limited space into a space with multiple functions to meet the requirements of its residents.

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A Study of Functional Assesment in Children With Cerebral Palsy (뇌성마비의 기능성평가도구에 대한 고찰 - GMFCS, GMFM 과 PEDI 중심으로 -)

  • Lyu, Sun-Ae;Kim, Bo-Kyong
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.1
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    • pp.13-42
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    • 2010
  • Objectives: This study is to investigate the method for assesment of cerebral palsy(CP), especislly focusing on function assesment Methods: We searched the recent date of the publication and paper in Cerebral Palsy Results: Measuring the function of children with cerebral palsy is mobility, self-care and social ability. Early adequate evaluation of motor development and prognosis of degree of long-term motor disability is very important not only for parents, but also for correct management of goal oriented rehabilitation treatment and for planning of preventive measures. 1. Gross Motor Function Classification System(GMFCS) is valuable to prognostication about gross motor progress in children with CP, using longitudinal observation. 2. Gross Motor Function Measure(GMFM) is the instrument most commonly used to measure gross motor function in children with cerebral palsy(CP). 3. Pediatric Evaluation of Disability Inventory(PEDI) is one of the most commonly used assessments for children with a disability. Conclusions: The functional Assesment of children with CP are used GMFCS, GMFM and PEDI.