• Journal of Korea Association of Health Promotion
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• v.3 no.1
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• pp.46-54
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• 2005

The functional dyspepsia is a complex disease reaction that ocurs due to the presence of various factors and its pathophysiology has not been clearly verified until now. This disease is diagnosed after the organic diseases are ruled out. Therefore, the main treatments are limited down to compensating for revealed symptoms through exercising the supportive care. The international prevalence of the functional dyspepsia under the Rome I criterior is approximately 25%. For the cases of Koreans, there are very omnifarious symptoms in gastrointestinal disorders and the medical vocabularies which describe the diagnostic standard are not closely associated with the daily vocabularies, thus there would be a lot of restrictions to directly apply the Rome II criterior. However, the Korean Society of Gastrointestinal motility had decided to promote the use of the international standardized Rome II criterior in order for Korea to be comparable to the clinical studies from the other nations. There should be more extensive studies to differentiate the definitions of symptom descriptions from Korea to foreign countries. The extended researches concerning the pathophysiology are highly recommended which in return, would help enabling the reliable treatment techniques for this disease.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.1
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• pp.36-43
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• 2010

Objectives: Since we found patients with dyspepsia as their major symptom had high rate of headache, would like to find out a rational diagnosis ground by using EAV correlation between headache and gastrointestinal disorder Methods: We did survey and EAV inspection on 128 patients came by gastrointestinal disorder who quoted 4 and 5 degree for their headache symptoms) Results & Conclusion The results of this study were as follows: 1. From dyspepsia, we saw higher rate by order of epigastric discomfort, bloating, stomach trouble, bleching, etc. 2. By EAV analysis, found functional deterioration by order of stomach, nerval degeneration vessel, gall bladder/bile duct, liver. 3. By EAV analysis, functional deterioration of stomach, gall bladder/bile duct, liver represent dyspepsia and nerval degeneration vessel represent headache. We found the correlation between dyspepsia and headache by observation at a time.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.142-149
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• 2006

Objectives : The aim of this study was to investigate the relationship between stress type and Ryodoraku score (RS) in patients with functional dyspepsia. Methods : 92 (30 male, 62 female) patients with functional dyspepsia were included in this study. Degree of stress was evaluated by GARS and BEPSI scale which can assess acute and chronic stress, respectively. RS of the patients was measured, and mean, sum of gaps and standard deviation (SD) in their RS were taken. First, patients were divided into two groups by sex, and by mean RS $40{\mu}A$ (above and below). GARS and BEPSI scale of each group was compared. Second, correlation between stress scales (GARS and BEPSI) and variation indexes of RS (sum of gaps and SD) was examined. Result : 1. The mean RS is higher in male patients than in female ones. 2. No significant difference was noted in GARS and BEPSI scale associated with above end below the mean $40{\mu}A$ RS. 3. The sum of gaps and SD of RS has significant correlation with GARS scale but not with BEPSI scale. Conclusions : These results suggest that the sum of gaps and SD of RS are associated with acute stress in patients with functional dyspepsia. Thus, it is thought that RS can be useful in assessing acute stress in patients with functional dyspepsia.

• Herbal Formula Science
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• v.14 no.2
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• pp.97-108
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• 2006

Objective: Functional dyspepsia refers to sustainable or repetitive pain at upper stomach related with food intake. This research was intended to observe the improvement of the symptom by administering Bowhatang to a number of functional dyspepsia patients and to clarify its clinical effects. Method: The research was performed upon the appropriate 36 patients conforming to the criteria after being diagnosed with functional dyspepsia among the 87 patients who visited the department of internal medicine at Gumi Oriental Hospital of Daegu Haany University for digestive diseases and were administered with Bowhatang. Result: 91.8% of the patients had upper stomach globus symptoms. which is of the largest percentage. and 13.5% had hunger pain. which is of the least percentage. After administering Bowhatang. by and large Likert scale was significantly reduced. According to the subjective improvement evaluation by the patients. 32 patients(86%) were improved. and 3 patients(8%) had neither improvement nor relapse. while 2 patients ( 6%) were relapsed. Conclusion: Bowhatang has shown significant improvement about the symptoms for functional dyspepsia patients. It is predicted when more outcomes become available from researches on side effects or toxicity of Bowhatang later on. it will be more often used in the clinic.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.6
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• pp.1094-1098
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• 2010

With the high prevalence of functional dyspepsia in the world, it was difficult to get objective diagnosis, treatment and assessment for the reason that there were many different symptoms and signs. The purpose of this study is to develop a standard instrument of pattern identification for functional dyspepsia which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 11 oriental division of gastroenterology professors of oriental medical colleges nationwide. The experts discussed developing the instrument, and we also took professional advices by e-mail. We divided the symptoms and signs of functional dyspepsia into 6 pattern identification, such as disharmony of liver and stomach, retention of undigested food, damp-heat in the spleen and stomach, simultaneous occurrence of cold and heat syndromes, deficiency and cold of the spleen and the stomach, and insufficiency of stomach eum. We got the mean weights to each symptom of six pattern identification which had been scored on a 5-point scale ranging from 1 to 5 by the 11 experts. We made out the Korean instrument of the pattern identification composed of 45 questions for functional dyspepsia. Although there are some limitations in our study, the instrument is meaningful and certain worth of its own. We hope to improve the instrument through the further clinical studies and discussions.

• Korean Journal of Acupuncture
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• v.34 no.1
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• pp.8-36
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• 2017

Objectives : The aim of this study is to review the methodology of clinical trials conducted with the acupuncture and moxibustion treatment on functional dyspepsia. Methods : We searched four international databases and three Korean databases including English, Korean and Chinese, through March 2016 for randomized controlled trials(RCT) and non-randomized case-control trials(CCT) that evaluated the effects of the acupuncture and moxibustion on functional dyspepsia. We abstracted the designs of the trials and the method of acupuncture and moxibustion treatment according to the Standards for Reporting Interventions in Clinical Trials of Acupuncture. Results : A total 117 papers were reviewed. The 106 studies were conducted in China. There were 111 RCTs(95%), and 6 CCTs(5%). Sixty eight studies(59%) were conducted with the manual acupuncture, 29 studies of electro-acupuncture(25%), 11 studies of moxibustion(9%), 5 studies of acupoints embedding therapy(4%), 4 studies of acupoint injection therapy(3%) were conducted. ST36, CV12, ST25 were most frequently used for acupoints to treat functional dyspepsia. In 59 studies(50%), western medication was used in the control group, and the effects of acupuncture and moxibustion were evaluated with the symptoms in most studies. Conclusions : These results suggest that it is necessary to develop more detailed reporting standards about acupuncture and moxibustion treatment method as the method of acupuncture and moxibustion is getting more diverse, and more objective tools are needed in evaluating functional dyspepsia.

• The Journal of Internal Korean Medicine
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• v.43 no.5
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• pp.918-928
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• 2022

Objectives: This study reports on the efficacy of Korean medical treatments for a functional dyspepsia patient with panic disorder and lower back pain. Methods: A 51-year-old male patient with functional dyspepsia was treated with herbal medicines and acupuncture for 17 days. The treatment effect was evaluated by measurements drawn from the Numerical Rating Scale, range of motion, Oswestry Disability Index, European Quality of Life 5 Dimensions Scale, and Gastrointestinal Symptom Score. Results: Following the treatment, the patient showed a decrease on the Numerical Rating Scale and Oswestry Disability Index and in Gastrointestinal Symptom Score, as well as an improvement in range of motion and European Quality of Life 5 Dimensions score. Conclusions: Korean medical treatments appear to be effective in reducing functional dyspepsia. Further clinical research on patients with functional dyspepsia is needed.

• The Journal of Internal Korean Medicine
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• v.43 no.5
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• pp.809-816
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• 2022

Objective: This study investigated the efficacy of using Korean medical treatments on a patient with functional dyspepsia. Methods: A 61-year-old female patient with functional dyspepsia and C/L-spine HIVD was treated with herbal medicine (Gamihyangsayukgunja-tang), acupuncture, pharmacopuncture, chuna manual therapy, and cupping therapy for 18 days. The treatment effects on the functional dyspepsia were evaluated using the Numerical Rating Scale score, Gastrointestinal Symptom Score, and Bristol Stool Scale results. Results: Following treatment, the patient showed decreases on the Numerical Rating Scale and Gastrointestinal Symptom Score and improvement on the Bristol Stool Scale. Conclusions: Korean medical treatment improved the condition of a patient with functional dyspepsia.

• Journal of Haehwa Medicine
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• v.18 no.1
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• pp.19-28
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• 2009

Objectives: This study was conducted to help clinical studies for treating Functional Dyspepsia with acupuncture. We inspected tendency of studies of acupuncture treatment for functional dyspepsia and analyzed the assessing instrument for it by scrutinizing Pubmed recent publications. Materials and Methods: We inspected 8 theses and scrutinized their objectives, periods, participants, materials and methods, the instrument of assessment for the studies, and criteria and symptom score for questionaire, results and JADAD score. Results: 1. Most studies were published by oriental doctors except one which was published by an American doctor. More and more studies are being published in America and written in English recently. So it is considered that western doctors think that the acupuncture treatment is useful as unorthodox medicine for functional dyspepsia. 2. Among the 4 clinical studies, 2 studies were RCT and 1 study was not RCT and 1 study with vagueness. All 4 clinical studies were not double-blinded because they were about comparison between acupuncture treatment and medicine. 3. ST36, PC6, CV12, BL21 were chiefly used, and auricular point, ST40, SP6 were also used. Manual acupuncture were used in 2 studies, and low frequency pulse and electroacupuncture were used in other studies respectively. 4. 4 clinical studies used 0~3 points symptom score as the instrument of assessment. Additional assessments were on gastric emptying time, EGG and plasma level of motilin. All thesis were not verified of validity and reliability. 5. Among the 4 reviewed thesis, 2 theses were about acupuncture as one of the various treatment of functional dyspepsia, and the other 2 theses were about efficacy of acupuncture treatment. And the result generally showed effectivity of acupuncture treatment. Conclusion: Acupuncture treatment for functional dyspepsia is considered useful as in unorthodox medicine by western doctors, and it is necessary to provide objective instrument for assessing acupuncture treatment for functional dyspepsia.

• Journal of Sasang Constitutional Medicine
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• v.30 no.2
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• pp.42-54
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• 2018

Objectives This study was aimed to compare effects of Yukgunja-tang (YGJT) extract granule on functional dyspepsia (FD) by sasang constitution. Methods A placebo-controlled, double-blind, randomized, two-center trial was performed. We obtained 3D face images of FD patients participating in this study using face-only scanner and classified them into two types as narrow face and wide face by 3D facial shape diagnosis system (3-FSDS). 96 subjects (48 subjects per type) were enrolled and were randomly allocated into treatment or control groups in a 2:1 ratio. YGJT extract granule or placebo were administered to each group during the 8 week treatment period. One of sasang constitutional specialist diagnosed their constitutions by referring to questionnaires and 3D face images. The primary outcome was total dyspepsia symptom scale (TDS scale), the secondary outcomes were single dyspepsia symptom scale (SDS scale), visual analog scale (VAS) and so on. This trial was registered with clinical research information service identifier: KCT0001920, 15 May, 2016. Results In the Taeeumin treatment group, the TDS scale was significantly decreased after 8 weeks compared to the control group (t=2.331, p=0.025) and the SDS scale also significantly decreased. (t=2.042, p=0.048). The specific effects of the YGJT extract granule without the placebo effect on the Taeeumin with functional dyspepsia were 30.61% in TDS scale and 28.33% in SDS scale. Conclusions The effects of Yukgunja-tang extract granule on functional dyspepsia was different according to Sasang constitution. So the constitution should be considered in randomized controlled trials using herbal extract granules.