• 지역사회간호학회지
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• 제19권4호
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• pp.575-586
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• 2008

Purpose: The purpose of this study is to identify factors affecting the constipation of the elderly at nursing homes. Method: A total of 184 elders at 7 nursing homes in P City participated. Information about constipation status (Constipation Assessment Scale). functional status (Katz' Activities of Daily Living). nutritional status (Mini-Nutritional Assessment). and depressive symptoms (Geriatric Depression Scale Short Form Korea version) were collected through interviews. Descriptive statistics. Chi-square test. and t-test were used to describe and compare the non constipation group and the constipation group. Multiple logistic regression analysis was used to determine factors affecting constipation status. Results: The prevalence of constipation was 47.5% (Men 37%. women 51%). Elders suffering from a disease (P=.021) and having low sleep satisfaction (P= .000) were more likely to be constipated than those who did not. The factors affecting the constipation of the elderly at nursing homes were gender (OR=3.558), sleep satisfaction (OR=.580), and depressive symptoms (OR=1.132). Conclusion: According to the result, to reduce the constipation rate of old women at nursing homes, we have to develop guidelines that can solve problems related to constipation cause by sleep-satisfaction and depressive symptoms.

• 한국축산식품학회지
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• 제44권1호
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• pp.119-131
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• 2024

BIOVITA 3 bacterial species (BIOVITA 3), a probiotic blend powder containing Clostridium butyricum IDCC 1301, Weizmannia coagulans IDCC 1201, and Bacillus subtilis IDCC 1101, has been used as a food ingredient for gut health. However, its efficacy in improving constipation has not been reported. Therefore, we aimed to investigate the functional effects of oral administration of BIOVITA 3 as well as its component strains alone (at 1.0×10⁹ CFU/day) in Sprague-Dawley (SD) rats with loperamide-induced constipation. The study included fecal analysis, gastrointestinal transit ratio, histopathological analysis, short chain fatty acids (SCFAs), and metagenome analysis. As results, the BIOVITA 3 group showed significant improvements in fecal number, water content, gastrointestinal transit ratio, and thickening of the mucosal layer. In the SCFAs analysis, all probiotic-treated groups showed an increase in total SCFAs compared to the loperamide-constipated group. Changes in microbial abundance and the diversity index of three groups (normal, constipated, and BIOVITA 3) were also defined. Of these, the BIOVITA 3 showed a significant improvement in loperamide-constipated SD-rats. This study suggests the possibility that BIOVITA 3 can be applied as an ingredient in functional foods to relieve constipation.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제12권sup1호
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• pp.111-117
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• 2009

Constipation is one of the most common symptoms that a child visits pediatrician. The general approach to the child with functional constipation includes the following steps; disimpaction, maintenance and withdrawal of medication. There are many drugs which can be applied to children; osmotic agents (lactulose, sorbitol, magnesium hydroxide/citrate, polyethylene glycol with/without electrolytes, sodium phosphate, glycerin), stimulants (senna, bisacodyl, caster oil), lubricant (mineral oil), bulking agent (psyllium, cellulose, glucomannan). At each stage of treatment, one or some of these drug can be applied to the purpose. The author tries to summarize recent studies on drugs for constipation in child, and finally introduces new dugs for constipation which is under investigation.

• Clinical and Experimental Pediatrics
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• 제51권11호
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• pp.1147-1151
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• 2008

Functional urinary incontinence, the absence of any neurologic or structural abnormality as a cause of urinary incontinence in children, is one of the most common clinical problems encountered in pediatric and urologic departments, and it can be socially and emotionally distressing for the affected children. The prevalence rates of functional urinary incontinence in school-aged children are not very high and differ between boys and girls. The underlying mechanisms of functional urinary incontinence are heterogenous and can be associated with the following dysfunctions of both the storage and voiding patterns of the bladder: overactive bladder, dysfunctional voiding, lazy bladder syndrome, HinmanAllen syndrome, giggle incontinence, and vaginal voiding. Treatment methods for urinary incontinence in children should be chosen according to these clinical conditions. Treatment modalities generally consist of the treatment of comorbid conditions such as urinary infection and constipation, behavior therapy to modify learned voiding patterns, and pharmacotherapy primarily with anticholinergics and ${\alpha}$-adrenergic blockers. This review discusses the optimal treatment modalities, including treatment of the underlying voiding disorders, and diagnostic approaches related to functional urinary incontinence in children.

• 한국약용작물학회지
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• 제24권6호
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• pp.471-478
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• 2016

Background: Constipation is one of the most common functional gastrointestinal disorder. The present study examined the ability of water extract of fermented (FRC) and non-fermented (NFRC) roasted Cassia tora to improve intestinal function and reduce constipation in a rat constipation model. Methods and Results: Different concentration of FRC and NFRC were orally administered loperamide (5 mg/kg; LOP) reduced the number, weight, and water content of feces, as well as intestinal transit motility. However, 24 h-(24 hour fermented roasted-Cassia tora) 300 mg/kg FRC administration increased the number, weight, and water concent of feces, compared to that seen in the LOP group, and also improve intestinal transit mitility and, the thickness of distal colon and mucous fluid. Conclusions: The results of the present study indicated that LOP-induced constipation was improved by treatment with FRC. Therefore FRC could be used to develop functional foods or natural medicine for constipation. However, further study is needed to clarify how fermentation improves the medicinal properties of roasted C. tora.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제17권3호
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• pp.155-161
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• 2014

Purpose: Constipation is a common pediatric problem worldwide. This study aims to describe the clinical characteristics of pediatric constipation in south Jordan according to gender and age group. Methods: All patients with constipation managed at our pediatric gastroenterology service between September 2009 and December 2012 were included. Hospital charts were reviewed. Demographic data, clinical characteristics, and final diagnosis were recorded. Data were analyzed according to gender and the following age groups: infants, pre-school, school age, and adolescents. Results: During the study period, 126 patients were enrolled. The number (percentage) of patients according to age were the following infants: 43 (34.1%), pre-school: 55 (43.7%), school age: 25 (19.8%), and adolescents: 3 (2.4%). Males made up 54.8% of the study population. There were no statistical gender differences in any age group. The most common symptom in all age groups was dry, hard stool. Infrequent defecation was found in almost one-half of the patients. Fecal incontinence was more common in school-aged children compared to pre-school-aged children and adolescents. Abdominal pain was seen in almost 40% of the constipated children. Abdominal pain was more prevalent in girls and older children. Fecal mass in the rectum was the most common physical finding, with constipated boys exhibiting higher rates. Functional constipation was the most common etiology. Conclusion: Clinical characteristics of constipation in children vary according to age group and gender. Older children had less frequent bowel motions, a longer duration of symptoms, and a higher prevalence of long-standing constipation compilations (fecal incontinence and abdominal pain).

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권1호
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• pp.28-33
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• 2018

Purpose: To evaluate the efficacy of synbiotic formula with partial whey hydrolysate and high magnesium content in infants presenting with functional constipation. Methods: Sixty-five infants with functional constipation were included. Forty infants were treated during one month with parental reassurance and the intervention formula and were compared to a control group of 25 infants treated with parental reassurance only. Parents completed a quality of life (QoL) questionnaire at baseline and during the last week of the study. Results: At inclusion, stool characteristics and QoL were similar in both groups. The control group was slightly older than the intervention group ($7.5{\pm}3.9$ vs. $6.2{\pm}3.6$ weeks). At onset, stool composition was "hard and tight" (Bristol stool scale 1 and 2) in all infants. After one month, stool composition remained unchanged in the control group except in two infants that developed "creamy" stools (Bristol stool scale type 3 and 4). In the intervention group, stools remained "hard and tight" in 27.5%, and became "creamy" in 47.5%, "loose" (Bristol stool scale type 5) in 22.5% and "watery" (Bristol stool type 6 and 7) in 2.5%. The benefit of the intervention formula was estimated to be "very important" in 70%. The median scores for QoL improved significantly in the intervention group for all parameters and for one in the control group. Conclusion: The intervention formula significantly improved functional constipation resulting in a better QoL of the parents and infants.

• Journal of Nutrition and Health
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• 제39권1호
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• pp.35-43
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• 2006

This study aimed to evaluate the effect of dietary fiber supplementation with snack type on functional constipation. We conducted a double blind case-control study with 3 groups; placebo, low dose group (LD: insoluble fiber 7 g/d + soluble fiber 1.2 g/d) and high dose group (HD: insoluble fiber 14 g/d + soluble fiber 2.4 g/d) , which were randomly assigned out of subjects with functional constipation, defined by modified Rome II criteria. We measured anthropometric parameters and evaluated the bowel movement frequency, stool type, straining, sense of complete evacuation, abdominal discomfort/pain, abdominal inflation, relief and colon transit time before, during the supplementation. Both LD and HD groups had significant improvement in straining, sense of complete evacuation and satisfactory relief compared with placebo group (p < 0.05). When subdivide by baseline colon transit time (less than 24 hrs/ 24 hrs or more and less than 72 hrs / 72 hrs or more), only HD group had significantly improvement; colon transit time recovered near by 24 hrs in subjects of 'less than 24 hrs' (from $7.57{\pm}1.40$ hrs to $25.2{\pm}3.91$ hrs, p < 0.01) and reduced in those of '24hr or more and less than 72 hr' (from $47.0{\pm}3.36$ hrs to $31.3{\pm}4.31$ hrs, p < 0.01) and '72 hr or more' (from $106.7{\pm}10.7$ hrs to $85.0{\pm}13.1$ hrs, P < 0.05) subjects. Particularly, positive effect of fiber supplementation on straining and sense of complete evacuation in test groups seemed to be greater in subjects of '24 hrs or less' and '24 hrs or more and less' than 72 hrs' than those of '72 hrs or more'. In conclusion, subjects with functional constipation, particularly those having colon transit time less than 72 hrs can significantly improve, at least in part, symptom related to constipation by fiber supplementation of snack type without serious side effects.

• Childhood Kidney Diseases
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• 제19권1호
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• pp.1-7
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• 2015

Coexisting voiding and bowel dysfunction in children are common in the clinic. The idea that overactive bladder (OAB) and constipation arise from one single pathophysiology has been reinforced in many studies. In Korea, a nationwide multicenter study conducted in 2009 showed that overall prevalence of OAB in children, 5-13 years of age, was 16.59% and this number has increased more recently. The initial step to manage coexisting fecal retention and OAB in children is to characterize their bowel and bladder habits and to treat constipation if present. Although diagnosing constipation in children is difficult, careful history-taking using the Bristol Stool Form Scale, and a scoring system of plain abdominal radiography, can help to estimate fecal retention more easily and promptly. Non-pharmacological approaches to manage functional constipation include increasing fluids, fiber intake, and physical activity. Several osmotic laxatives are also effective in improving OAB symptoms and fecal retention. Additionally, correction and education in relation to toilet training is the most important measure in treating OAB with fecal retention.

• Journal of Nutrition and Health
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• 제42권8호
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• pp.702-713
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• 2009

대학생들의 변비유병률과 배변습관을 알아보고 영양소섭취 상태를 알아보고자 인천지역 대학교에서 건강관련 교양강의를 듣는 수강생들을 대상으로 (남자 166명, 여자 187명) 설문조사와 신체계측 및 3일간 식이섭취 조사를 실시한 결과는 다음과 같다. 조사 대상자의 평균 연령은 남학생 23.5세, 여학생 20.9세이었으며, 자택에서 거주하는 비율이 가장 많았으며 자취, 기숙사, 하숙이나 친척집에 거주하는 순이었다. 남학생의 63.9%, 여학생의 63.1%는 21~40만원의 용돈을 받고 있었고 지난 2개월 동안 남학생의 45.2%, 여학생의 47.1%는 체중을 유지하고 있었다. 로마기준 II를 이용하여 조사한 기능성 변비유병률은 남녀 각각 12.7%, 28.9%, 자의적 변비 유병률은 남녀 각각 12.0%, 36.9%로 여학생이 남학생에 비해 유의적으로 높았으며 일반사항에 따른 기능성 변비와 자의적 변비의 차이는 보이지 않았다. 자의적 변비 중 남학생의 35.0%, 여학생의 44.9%만이 기능성 변비의 진단기준에 부합하였고, 본인은 변비가 아니라고 응답했지만 기능성 변비의 진단기준에 부합한 경우는 11.4%이었다. 본인이 변비라고 인식하는 경우 남학생의 94.7%, 여학생의 91.0%는 의료기관을 방문한 경험이 없었고 남학생은 모두 변비약이나 건강기능식품을 이용하고 있지 않았으며 여학생은 변비 완화를 위해 10.3%가 변비약, 11.8%가 건강기능식품을 복용하고 있었다. 배변습관 조사 결과 남학생의 75.3%, 여학생의 40.1%는 주 5회 이상 배변을 하고 있었고, 변의 양은 2 cup 이상이라고 응답한 경우가 남학생은 93.4%, 여학생은 75.9%로 남학생이 많은 경향을 보였다. 남녀 모두 대상자의 70%정도가 배변 후 상쾌하다고 하였으며 남학생의 49.4%, 여학생의 24.6%만이 규칙적으로 배변을 하였다. 신체계측치와 영양소 섭취량 분석 결과 기능성 변비와 자의적 변비 유무에 따른 차이는 보이지 않았으나 단백질의 경우 성별이나 변비 유무와 상관없이 RI에서 UL 사이로 섭취하는 비율이 가장 높았고, 남학생은 여학생에 비해 EAR 보다 낮게 섭취하는 비율이 유의적으로 높았다. 비타민 C, Vit $B_2$, 엽산, 칼슘, 아연의 섭취는 EAR 이하로 섭취하는 비율이 모두 50%를 넘어 영양소의 섭취량이 매우 낮음을 알 수 있었고 특히 엽산은 남녀 모두 95% 이상이 EAR 이하로 섭취하고 있어 섭취 부족이 심각하였다. 변비와 관련이 있는 것으로 알려진 식이섬유 섭취량은 1,000 kcal당 섭취량으로 환산에 남학생은 8.5 g, 여학생은 8.9 g으로 한국인 영양섭취기준의 식이섬유 충분섭취량에 훨씬 못 미치는 수준이었다. 여학생의 경우 기능성 변비의 유병률은 28.9%, 자의적 변비의 유병률은 36.9%로 조사되었는데, 본인은 변비가 아니라고 응답했지만 기능성 변비의 진단기준에 부합한 경우도 13.6%이며 본인이 변비라고 응답한 경우의 대다수는 의료기관 방문이나 약물, 기능성 식품 섭취 같은 노력도 하지 않고 있어 만성적 변비로 인한 질병의 위험이 우려된다. 또한 식이섬유 섭취를 비롯한 각종 영양소들도 균형 있는 섭취를 하고 있지 않아 이후 다가올 임신기와 수유기의 영양문제로 이어질 것이므로 올바른 영양섭취를 비롯한 적절한 영양교육이 활성화 되어야겠다.