• 제목/요약/키워드: functional compounds

검색결과 1,180건 처리시간 0.029초

High-throughput Preparation and Characterization of Powder and Thin-film Library for Electrode Materials

  • Fujimoto, Kenjiro;Onoda, Kazuhiro;Ito, Shigeru
    • 한국분말야금학회:학술대회논문집
    • /
    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
    • /
    • pp.254-255
    • /
    • 2006
  • Powder library of pseudo four components Li-Ni-Co-Ti compounds were prepared for exploring the composition region with the single phase of the layer-type structure by using combinatorial high-throuput preparation system "M-ist Combi" based on electrostatic spray deposition method. The new layer-type compounds were found wider composition region than the previous report. This process is promising way to find multi component functional materials.

  • PDF

Selective Reduction of Carbonyl Compounds with Diisopinocampheylhaloboranes

  • 차진순;김은주;권오운;김종미
    • Bulletin of the Korean Chemical Society
    • /
    • 제17권1호
    • /
    • pp.50-55
    • /
    • 1996
  • Reaction of carbonyl compounds with diisopinocampheylhaloboranes (Ipc2BX,X=Cl, Br, I) was investigated in detail in order to establish their usefulness as selective reducing agents. The reagents reduced aldehydes and ketones to the corresponding alcohols. The reactivities are in the order of Ipc2BCl Ipc2BBr>Ipc2BI.The reagents also reduced ${\alpha}{\beta}-unsaturated$, aldehydes and ketones to the corresponding allylic alcohols without any detectable 1,4-reduction. Especially, the chloro derivative nicely achieved the selective reduction of aldehyde or ketone groups in the presence of many other functional groups. The most remarkable result of this investigation is that aldehydes and ketones can be selectively reduced in the presence of acid chlorides.

Selective Reduction of Carbonyl Compounds with Dilsobutyldialkylaminoalanes

  • 차진순;권상용;권오운;김종미;송한철
    • Bulletin of the Korean Chemical Society
    • /
    • 제17권10호
    • /
    • pp.900-905
    • /
    • 1996
  • Details are described of reaction of carbonyl compounds with diisobutyldialkylaminoalane (DIBAL-NR2; R=Et, i-Bu, Ph) in order to establish their reduction characteristics. The reagents were extremely mild and reduced only aldehydes and ketones effectively in ethyl ether at 25 ℃. The stereoselectivity in the reduction of representative cyclic ketones appeared not so high but quite different from that obtained by DIBAL-H itself. The reagents reduced α,β-unsaturated aldehydes and ketones to the corresponding allylic alcohols without any detectable 1,4-reduction products. DIBAL-NR2 also achieved the selective reduction of aldehydes or ketones in the presence of keto or other readily reducible functional group, however the chemoselectivity was less satisfactory than that achieved by diisobutylethoxyalane (DI-BAL-OEt).

Selective Data Reduction in Gas Chromatography/Infrared Spectrometry

  • 표동진;신현두
    • Bulletin of the Korean Chemical Society
    • /
    • 제22권5호
    • /
    • pp.488-492
    • /
    • 2001
  • As gas chromatography/infrared spectrometry (GC/IR) becomes routinely avaliable, methods must be developed to deal with the large amount of data produced. We demonstrate computer methods that quickly search through a large data file, locating thos e spectra that display a spectral feature of interest. Based on a modified library search routine, these selective data reduction methods retrieve all or nearly all of the compounds of interest, while rejecting the vast majority of unrelated compounds. To overcome the shifting problem of IR spectra, a search method of moving the average pattern was designed. In this moving pattern search, the average pattern of a particular functional group was not held stationary, but was allowed to be moved a little bit right and left.

Selective Reduction of Carbonyl Compounds with Al-Alkoxydiisobutylalanes

  • 차진순;권오운;김종미;전중현;이영수;이형수;조성동
    • Bulletin of the Korean Chemical Society
    • /
    • 제19권2호
    • /
    • pp.236-242
    • /
    • 1998
  • Reaction of carbonyl compounds with Al-alkoxydiisobutylalane (DIBAOR, R=H, Et, i-Pr, t-Bu) has been investigated in detail so as to establish their usefulness as selective reducing agents in organic synthesis. The reagents appear to be extremely mild and can reduce only aldehydes and ketones effectively under mild conditions. All the other common organic functional groups are not affected by these reagents. The reagents can also reduce α,β-unsaturated aldehydes and ketones to the corresponding allylic alcohols without any detectable 1,4-reduction. Furthermore, the reagents show a highly chemoselective discrimination between aldehyde and ketone, between aldehydes, and between ketones. Even more remarkable is the stereoselective reduction of cyclic ketones to the thermodynamically more stable alcohol epimers.

Simultaneous determination of phytochemical constituents in Paeonia lactiflora extracts using the HPLC-UV method

  • Kim, Juree;Choi, Jungwon;Kang, Sam Sik;Lee, Sanghyun
    • Journal of Applied Biological Chemistry
    • /
    • 제64권1호
    • /
    • pp.13-17
    • /
    • 2021
  • Qantitative analysis of six compounds: (+)-catechin, benzoic acid, gallic acid methyl ester, paeonol, paeoniflorin, and albiflorin from Paeonia lactiflora extracts was performed using high-performance liquid chromatography and an ultraviolet (UV) detector, following different extraction methods. A reverse-phase column was used in a gradient elution system, and UV detection was performed at 280 nm. The results showed that the quantity of paeoniflorin was the highest in ethanol and water extracts (73.89 and 57.87 mg/g, respectively) among the six compounds. This study contributes a good analysis method for the contents of P. lactiflora and would be propitious for developing medicines and functional foods.

콩 불마름병 방제를 위한 살균제 선발 (Selection of Bactericides for Controlling Soybean Bacterial Pustule)

  • 홍성준;김용기;지형진;이봉춘;윤영남;박성태
    • 식물병연구
    • /
    • 제16권3호
    • /
    • pp.266-273
    • /
    • 2010
  • Xanthomonas axonopodis pv. glycines에 의해 발병되는 콩 불마름병은 콩에 가장 많이 발생하는 중요한 세균성 병해 중 하나이다. 게다가 병원균은 강한 병원성을 가지고 한국 전역에 분포하고 있지만, 한국에서는 불마름병방제를 위한 약제나 저항성 품종이 개발되어 있지 못한 실정이다. 따라서 본 연구의 목적은 불마름병을 화학적 방법으로 방제할 수 있는 방법을 개발하기 위해 수행되었다. 콩 불마름병 병원균의 효과적인 생육억제 약제를 선발하기 위해 여러 가지 살세균제들(8개의 항생제, 2개의 구리화합물, 1개의 quinoline, 18개의 농약)을 이용하여 효과를 확인하였다. 실내 생장억제 효과조사 결과, tetracycline, streptomycin sulfate 처리에서 병원균의 생육이 크게 억제되었으며, 또한 oxolinic acid도 병원균의 생육억제 효과가 우수하였다. 하지만 vancomycin, polymyxin B sulfate and copper compounds 등은 불마름병 병원균의 생육억제효과가 확인되지 않았다. 18종의 농용약제 중에는 streptomycin sulfate + oxytetracycline(18.8 + 1.5%)WP, oxytetracycline(17%)WP, oxolinic acid(20%) 등이 실내에서 병원균의 생육억제 효과가 높은 것으로 조사되었다. 선발된 5종의 농용약제에 대하여 포장에서 방제효과 시험을 실시한 결과, streptomycin sulfate + oxytetracycline (18.8 + 1.5%) WP와 oxytetracycline(17%) WP가 자연 감염된 태광콩 포장에서 70% 이상의 높은 방제효과를 나타내었다. 그러므로 콩불마름병균에 대한 강한 억제효과를 가지는 이 약제들은 콩 불마름병의 화학적 방제에 실용성이 있을 것으로 생각된다.

양념 소갈비의 조리과정에서의 물리화학적 특성 평가 (The Physicochemical Characteristics of Marinated Beef Galbi under Different Cooking Conditions)

  • 홍상필;김영호;이남혁;허영욱
    • 한국식생활문화학회지
    • /
    • 제28권1호
    • /
    • pp.78-88
    • /
    • 2013
  • Marinated beef galbi is a traditional Korean dish cooked with soy sauce, pear juice, onion, sesame oil, and sugar. However, there are many differences in beef galbi, including flavor and physicochemical aspects, depending on cooking conditions. Therefore, the physicochemical characteristics of marinated beef galbi prepared through various recipes was evaluated for its effects on pH, texture, aging, proteolysis, heating conditions, cooking time, and flavor compounds (pyrazines, IMPs, or FAAs). There were significant differences in salt concentration (0.8~3.03%), pH (4.89~6.22), and solid soluble contents (1.34-6.31 Brix) between recipes in this study. In the Pearson assay for sensory evaluation, overall preference correlated well with texture (a well-known sensory attribute in meat evaluation). Controlling the pH of meat through soaking in lemon solution, alkali water, phosphate, and baking powder solution, improved water holding capacity as much as 9 to 15% compared with the control. The myofibril index (MFI) of marinated meat stored at $4^{\circ}C$ increased 32% with 24 hours of aging and reached 39% at 48 hours of aging, and its fragmentation was observed through microscopy. SDS-PAGE showed hydrolysis of acid-soluble collagen by the pear juice, possibly related to meat tenderness. On the basis of surface temperature, the cooking time was estimated to be 8 minutes with pan heating at $170^{\circ}C$, 6 minutes at $270{\sim}300^{\circ}C$, and 4 minutes with charcoal at $700{\sim}900^{\circ}C$. Different pyrazine compounds, such as 2-methyl-3-phenylpyrrol(2,3-b) pyrazine (the typical product of the browning reaction) was mainly detected, and IMP (one of the main taste compounds in beef) was in higher amounts with the charcoal treatment, potentially related to its flavor preference among treatments. Our results demonstrate an effective case study and cooking system for beef galbi.

Current status of natural product industry and its commercial application to health functional foods

  • Park, Jong Dae
    • 한국자원식물학회:학술대회논문집
    • /
    • 한국자원식물학회 2018년도 추계학술대회
    • /
    • pp.21-21
    • /
    • 2018
  • Natural product substances have historically served as the most significant also be prepared by source of new leads for pharmaceutical development. They can chemical synthesis(both semisynthesis and total synthesis) and have played a important role in the field of organic chemistry by providing synthetic targets. Rcently, they have also been extended for commercial purpose to refer to medicinal products, health functional foods, dietary supplements and cosmetics from natural sources. A large number of currently prescribed drugs have been either directly derived from or inspired by natural products. However, with the advent of robotics, bioinformatics, high throughput screening(HTS), molecular biology-biotechnology, combinatorial chemistry, in silico(molecular modeling) and other methodologies, the pharmaceutical industry has largely moved away from plant derived natural products as a source for leads and prospective drug candidates. The strategy for natural prduct industry is now changing from drug approaches to health foods by identifying effective natural products as preparations. In Korea, a lot of development of natural product based drugs have been done, but very few on health functional foods. The concept of natural product based health foods is not active components as lead compounds but standardized extracts or preparation mixed with other medicinal plants. The representative material has been recently known to be a standardized ginseng extract "Ginsana G 115" developed by Swiss Pharmaton company. The purpose of this presentation is to underline how natural products research continues to make significant contributions in the domain of discovery and development of new health functional foods. It is proposed to present the development of high value added health food or health functional foods through scientific investigation on efficacy and standardization of new materials form natural products.

  • PDF

노화가속화 조건에서 저장 기간에 따른 귀리의 기능성 성분 및 항산화 활성 변화 (Changes in Functional Compounds and Antioxidant Activities in Storage Duration with Accelerated Age-Conditioning of Oats)

  • 손유림;이지혜;박형호;이병원;김현주;한상익;우관식;이병규;이상철;이유영
    • 한국작물학회지
    • /
    • 제63권2호
    • /
    • pp.149-157
    • /
    • 2018
  • 국내 육성 귀리인 대양, 조양, 조풍을 노화가속화 조건($45^{\circ}C$, RH < 20%)에서 63일간 저장하였을 때, 귀리의 기능성 성분과 항산화 활성 변화는 아래와 같다. 1. 단백질, 지방 함량은 세 품종 모두 저장 기간 동안 큰 변화 없이 유지되었다. 2. 항산화성분 중 아베난쓰라마이드는 저장 기간 동안 함량이 유지되었지만, 비타민 E는 63일의 저장 기간 동안 대양과 조양 품종에서 함량이 감소하는 경향을 보였다. 3. 조양과 조풍은 저장 후 베타글루칸 함량과 불포화지방산 함량이 점점 증가하였지만, 대양은 원곡의 함량을 유지하였다. 4. 항산화 활성 측정 결과, 대양은 저장기간 동안 큰폭의 변화없이 함량을 유지한 반면, 조양과 조풍은 42일 이후 감소하는 양상을 보였다.