• 제목/요약/키워드: free fatty acid level

검색결과 294건 처리시간 0.032초

이진탕가창출백출(二陳湯加蒼朮白朮)이 고지방 식이로 유발된 생쥐의 비만증에 미치는 영향 (Experimental Effects of Ijin-tang add Atractylodis Rhizoma and Atratcylodis Macrocephalae Rhizoma Extract in Obese Mice Induced by High Fat Diet)

  • 이상영;정현우
    • 동의생리병리학회지
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    • 제22권1호
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    • pp.89-95
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    • 2008
  • This experimental study was designed to investigate the effects of Ijin-tang add Atractylodis rhizoma and Atratcylodis macrocephalae rhizoma (IJTAA) on the change of weight and serum total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, free fatty acid, total lipid and phospholipid level in obese mice induced by high fat diet. Experimental groups were as follows ; Normal group was fed normal diet and administered distilled water during 7 weeks, Control group was fed high fat diet and administered distilled water during 7 weeks, Sample A group was fed high fat diet and administered IJTAA 500 ㎎/㎏/day/mouse during 7 weeks, Sample B group was fed high fat diet and administered IJTAA 700 ㎎/㎏/day/mouse during 7 weeks. The results were as follows ; 1. In Sample A group and Sample B group, There were significantly decreased in body weight, serum total cholesterol level, serum triglyceride level, serum free fatty acid level, serum total lipid level and serum phospholipid level in comparison with Control group. 2. In Sample A group and Sample B group, There were significantly increased in serum HDL-cholesterol level in comparison with Control group. 3. In Sample A group and Sample B group, There were decreased in serum LDL-cholesterol level in comparison with Control group. According to above results, I suggest IJTAA is able to be used for managing obesity by controllong body weight, serum total cholesterol level, serum triglyceride level, serum free fatty acid level, serum total lipid level and serum phospholipid level.

발생중인 닭의 배자에서 뇌 조직내 인지질의 지방산 조성 변화 (Changes of Fatty Acid Compositions in Brain Phospholipids of Developing Chicken Embryos)

  • 김희성;최인숙;지규만
    • 한국가금학회지
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    • 제22권1호
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    • pp.31-42
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    • 1995
  • This study was to investigate the effects of dietary linoleic acid(18:2\omega6, LA) and aipha-linolenic acid(18:3\omega3. \alpha-LNA) levels on brain development and fatty acid compositions of various lipid classes in the chicken embryo brain tissues. Thirty two ISA Brown layers, 52 weeks-old, were divided into four groups. Birds of each group were given corn-soybean meal based diets added with 1) safflower oil 8%, 2) safflower oil 6% + perilla oil 2%, 3) safflower oil 2% + perilla oil 6%, or 4) perilla oil 8%. Mter 15 days fed the diets. the layers were artificially inseminated to obtain fertile eggs. During the incubation. embryonic brains were sampled at 15th and 21st days. Fatty acid contents were quantitated by using heptadecanoic acid (17:0) as an internal standard. No significant differences in brain weight and in contents of various lipids such as phospholipid. triglyceride, cholesterol. cholesterol ester and free fatty acid in the tissues were found among the dietary groups (P<0.05). The ratios of AA/LA in the brain lipid classes were lowered as the dietary levels of perilla oil were increased. Higher LA was found in phosphatidylcholine(PC) than arachidonic acid (20:4\omega6. AA), meanwhile the level of LA was less than AA in phosphatidylethanolamine(PE). Docosahexaenoic acid(22:6\omega3, DHA) was the* major fatty acid in the tissue and its content in PE was 2.5~3 times higher than in PC. DHA level in the phospholipid reached at a peak (1.7~1.8 mg/brain) in dietary groups added with 6% or 8% perilla oil. suggesting that no more increase in that fatty acid level in the brain tissue could be obtained by consuming more \alpha-LNA, the major precursor of DHA.

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결명자 분획물이 당뇨 유발 흰쥐의 혈당에 미치는 영향 (Hypoglycemic Effect of Fractions of Cassia tora Extract in Streptozotocin-Induced Diabetic Rats)

  • 임숙자;한혜경
    • 한국식품조리과학회지
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    • 제13권1호
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    • pp.23-29
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    • 1997
  • The hypoglycemic effect of fractions of methanol extract of Cassia tora was investigated in diabetic rats. Sprague-Dawley male rats weighing 180∼230 g were divided into 6 groups. Diabetes was induced in the male rats by intravenous injection of streptozotocin at a dose of 45 mg/kg dissolved in citrate buffer (pH 4.5). The diabetic animals then had plasma glucose concentration of above 300 mg/㎗. Fractions of methanol extract of Cassia tora were administered orally into the diabetic rats for 14 days after streptozotocin injection. The food intake and body weight gain were monitored and plasma levels of glucose, triglyceride, free fatty acid, HDL-cholesterol, cholesterol and ALT activity were determined. Levels of glycogen, cholesterol and triglyceride in liver were analysed. Weights of liver and kidney were lighter in all the fraction-administered groups than streptozotocin-control group. Plasma glucose level was significantly decreased by the administration of butanol fraction at 14 days. Plasma triglyceride levels were lower in chloroform, butanol and H$_2$O fraction-administered groups compared to streptozotocin-control group. Plasma cholesterol and HDL-cholesterol levels were not significantly different in all groups. Administrations of each of the four fractions have decreased plasma free fatty acid level, ALT activity and liver triglyceride levels in the diabetic rats. Liver glycogen levels in chloroform, butanol and H$_2$O fraction-administered groups were higher than streptozotocin-control group. It is suggested from the results that butanol fraction of methanol extract of Cassia tora may contain the antihyperglycemic compounds.

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2-Acetylaminofluorene의 투여와 나이에 따른 쥐의 세포막 지방산 조성 및 지질과산화물 생성의 변화 (Age Related Changes of Microsomal Fatty Acid Composition and Lipid Peroxidation in 2-acetylaminofluorene Treated rats.)

  • 윤은영;최혜미;김현아;김숙희
    • 한국환경성돌연변이발암원학회지
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    • 제15권2호
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    • pp.140-147
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    • 1995
  • For studying the effect of different dietary fats on carcinogenesis, fatty acid composition of membrane and lipid peroxidation were measured. Male Sprague-Dawley rats were fed on diet containing 15%(w/w) beef tallow or soybean oil. A single dose of 50 mg 2-AAF/kg B.W. was injected i.p. in each diet group 10 times. Rats were sacrifled after 1, 5, 10, and 15 weeks from the first injection. By 2-AAF injection, !ipid peroxidation increased slightly compared to control group. The rats fed on different fats had similar MDA production and those fed on soybean oil had slightly higher free radical concentration measured by ESR. In young rats, iipid peroxidation level was high and hydroxy radical production was higher in soybean oil group than in beef tallow group. With age, the lipid peroxidation values were decreased initially then increased. The fatty acid composition in microsomal membrane was reflected by dietary fatty acid composition. In soybean oil group, monoenoic acid was lower and polyunsaturated fatty acid was higher than beef tallow group. Linoleic acid contents showed the most discrepancy among groups. By 2-AAF treatment, iinoleic acid content and unsaturation index increased in soybean oil group. But in beef tallow group, there was no difference in fatty acid contents.

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부유망식과 수하식 양성방법에 따른 참굴(Crassostrea gigas)의 영양상태 (Evaluation of Nutrients during Rack and Bag Culture or Suspended Culture of Pacific Oyster Crassostrea gigas)

  • 최용준;;이정미;강석중;최병대
    • 한국수산과학회지
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    • 제50권3호
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    • pp.263-269
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    • 2017
  • The mineral contents, and free amino acid, and fatty acid composition of rack and bag or suspended cultured oysters Crassostrea gigas were compared. The moisture content did not change much from 82.8% to 86.3% in the different culture methods. The glycogen level was low 4.7% during rack and bag culture but high 7.2% during suspended culture. The sodium level was the highest during suspended culture, while copper and zinc level were highest during rack and bag culture. The taurine level was 1,385-1,375 mg/100 g in oyster cultured using the rack and bag method, but that in the market sample was lowest at 1,015.8 mg/100 g. Hydroxyproline, glutamic acid, proline, glycine, and alanine were detected at high levels in the experimental oysters. The polyunsaturated fatty acid content was similar among samples. The docosahexaenoic acid level was 14% with rack and bag culture and 12% with suspended culture, whereas the eicosapentaenoic acid level was 15% with rack and bag culture and 20% with suspended culture. The atherogenic index (AI), thrombogenicity index (TI), and hypocholesterolemic/ hypercholesterolemic (h/H) ratio were important factors in the nutritional evaluation. The AI and TI values were 0.5-0.2, and the h/H ratio were 2.0 and 2.4 with the rack and bag and suspended culture, respectively.

표고버섯을 첨가한 전통된장의 이화학적 특성 (Physicochemical Characteristics of Traditional Doenjang with added Lentinus edodes)

  • 최선영;성낙주;김행자
    • 한국식품조리과학회지
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    • 제22권1호
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    • pp.69-79
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    • 2006
  • Traditional doenjang with Lentinus edodes added at a concentration of 0, 3, 5 and 10% (w/w) was prepared and its physicochemical characteristics were analyzed during fermentation for 6 months. The moisture content, salt level and pH for doenjang were decreased with increasing addition of Lentinus edodes powder, but crude protein content was increased. Among the free sugars, glucose, galactose, arabinose, sucrose and maltose were identified and quantified, with the first two being the major free sugar. Minerals were detected in the order of Na> K> P> Ca> Mg> Fe while the content of Cu, Mn and Zn exhibited little change. The contents of each amino acid of traditional doenjang with added Lentinus edodes, glutamic, leucine and aspartic acids, had a much higher level. In fatty acid compositions, palmitic, stearic, oleic and linoleic acids were analyzed, with oleic acid being the most abundant fatty acid at $56.4{\pm}0.8\sim57.5{\pm}0.5%$ in all the tested samples. GMP and IMP contents of nucleotides and their related compounds were extremely high. It was thought that these substances contributed to the sweet taste of traditional doenjang with added Lentinus edodes. These results showed the applicability and high quality of traditional doenjang with added Lentinus edodes.

생강다대기의 저장 중 품질특성 (Quality Characteristics of Minced Ginger During Storage)

  • 이명희;이영경;김경탁
    • 한국식품저장유통학회지
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    • 제17권1호
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    • pp.23-29
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    • 2010
  • 본 연구에서는 식초, 주정 및 비타민 C 등의 첨가물을 넣어 제조한 생강다대기를 튜브용 용기에 담아 $10^{\circ}C,\;20^{\circ}C,\;30^{\circ}C$에서 각각 보관하면서 저장기간별로 미생물 수, 색도, 향기성분변화, 유리당, 유리아미노산 및 지방산의 특성변화를 살펴보았다. 생강다대기의 일반세균수는 저장기간 동안 미생물 수의 변화가 거의 없었고, 곰팡이의 경우 생강다대기에서 존재하지 않는 것을 확인하였다. 효모의 경우 저장초기 $5{\times}10^1$ CFU/g의 효모가 존재하였으나, 저장 2주경과 후부터 존재하지 않는 것을 확인하였다. 생강다대기의 저장 중 색도를 측정한 결과, 저장기간이 경과할수록 그리고 저장온도가 높을수록 색깔의 변화가 증가하는 것을 볼 수 있었다. 생강다대기의 저장온도에 따른 향기성분은 저장초기와 비교하여 17주 경과 후 생강다대기의 향기성분의 총 함량이 다소 감소하는 경향을 나타내었다. 생강다대기 중의 유리당은 저장기간이 경과함에 따라서 sucrose 함량은 감소하고, fructose 및 glucose 함량은 증가하였다가 감소하는 경향을 나타내었다. 유리아미노산의 경우 저장온도가 높을수록 약간 감소하는 경향을 나타내었으며, 주요 아미노산 성분으로 glutamine, valine, alanine, asparagine, tyrosine 및 leucine이 검출되었다. 생강다대기의 지방산의 변화를 살펴본 결과 초기치 지방산 함량에 비하여 조금 증가한 결과를 나타내었고, 지방산의 조성으로 불포화 지방산보다 포화지방산의 비율이 높게 나타났다.

부잠폐수의 성상과 유출 유지의 성분 (Features of Waste Water form By-Product Silk Treatment and Composition of Extracted Lipid)

  • 남영락;설대석
    • 한국잠사곤충학회지
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    • 제33권2호
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    • pp.100-102
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    • 1991
  • 제사공정의 부잠사 처리폐수에 대하여 그 성상과 추출 유지성분을 분석한 결과 1. 부잠폐수의 COD 605mgO/$\ell$ 총 용존 고형물량 2,335mg/$\ell$ 총 부유 고형물량 2,234mg/$\ell$이었다. 2. 부잠폐수의 지질에는 triglyceride가 76.8%로 가장 많이 함유되었으며 유리 지방산 12.5%와 diglyceride 5.7% free sterol 5.0% 순이었다. 3. 부잠폐수지질의 지방산 조성은 oleic acid, linolenic acid와 linoleic acid의 함유율이 64.93%로 가장 많이 함유되어 있고 palmitic acid 29.39% stearic acid 4.93%의 순이었다.

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비타민E와 셀렌이 흰쥐의 혈청(血淸) 및 간장(肝臟)중의 지질성분(脂質成分)에 미치는 영향(影禦) (Effect of Vitamin E and Selenium on the Lipid Composition in Serum and Liver of Rats)

  • 김선영;조수열
    • 한국식품영양과학회지
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    • 제14권1호
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    • pp.33-38
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    • 1985
  • 지질(脂質)의 항산화제(抗酸化制)인 vitamin E와 selenium이 백서(白鼠)의 혈청(血淸) 및 간(肝)의 지질성분(脂質成分)에 미치는 영향(影響)을 조사(調査)하고 이를 서로 비교(比較)하기 위하여 본(本) 실험(實驗)에서는 vitamin E와 selenium이 결핍(缺乏)한 기본식이(基本食餌)에 dl-${\alpha}$-tocopheryl acetate 200 mg 과 sodium selenite 0.5 ppm 을 rkr(各) 군(群)에 따라 급여(給與)하고 6주간(週間) 사육(飼育)한 후(後) 백서(白鼠)의 체중증가량(體重增加量), 사료효율(飼料效率), 각종(各種) 장기(臟器) 중량(重量), 혈청(血淸) 및 간(肝)의 지질성분(脂質成分)을 측정(測定), 고안(考案)한 결과(結果) 다음과 같았다. 1. 체중증가량(體重增加量)과 사료효율(飼料效率)은 vitamin E나 selenium을 공급(供給)한 군(群)이 결핍(缺乏)한 군(群)보다 높았고 함께 공급(供給)한 군(群)이 가장 높았다. 2. 각종(各種) 장기(臟器)의 중량(重量)에서 신장(腎臟), 심장(心臟), 폐장(肺臟)은 실험군간(實驗群間)에 별다른 차이(差異)가 없었고 간장(肝臟)의 중량(重量)은 vitamin E나 selenium을 공급(供給)함에 따라 감소(減少)하였고 간장(肝臟)의 중량(重量)은 vitamin E의 공급(供給)에 의해 유의(有意)하게 감소(減少)하였다. 3. 혈청(血淸)중의 total lipid량(量)은 유의성(有意性)이 없으며 vitamin E의 공급(供給)에 의해 cholesterol량(量)은 감소(減少)하였고 triglyceride와 free fatty acid의 함량(含量)은 증가(增加)하였으나 selenium의 공급(供給)은 아무런 변화(變化)가 없었다. 4. 간장(肝臟)중의 crude lipid, cholesterol, triglyceride 및 free fatty acide의 함량(含量)은 vitamin E나 selenium의 공급(供給)에 으ㅢ해 유의(有意)하게 감소(減少)하였다. 5. 간장(肝臟)중의 지방산(脂肪酸) 조성(組成)은 포화지방산(飽和脂肪酸)과 oleic acid의 경우 유의성(有意性)이 없었고 oleic acid은 대체로 높은 비율(比率)이었으며 linoleic acid은 selenium공급(供給)에 의해, arachidonic acid은 vitamin E나 selenium의 공급(供給)에 의해 유의(有意)하게 감소(減少)하였다.

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식용 돼지췌장 리파제가 저급지방산 생성과 체다치즈 풍미향상에 미치는 영향 (Effects of Food Grade Porcine Pancreatic Lipase on the Production of Short-Chain Fatty Acids and its Contribution)

  • 곽해수;전익준;박정남
    • 한국식품과학회지
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    • 제22권3호
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    • pp.248-254
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    • 1990
  • 식용 돼지췌장 리파제를 두 가지 함량으로 치즈제조시 혼합하여 $7^{\circ},\;13^{\circ},\;21^{\circ}C$에서 숙성시켰다. GC 분석결과 효소처리한 치즈에서는 Control에서 보다 훨씬 많은 양의 저급지방산이 생성되었다. 돼지췌장 리파제를 많이 넣어 $21^{\circ}C$에서 숙성시킨 치즈의 경우 1주 후에 medium flavor 치즈, 3주 후에 거의 sharp flavor 치즈가 특별한 결함없이 생산되었다. 또한 이 효소를 조금 넣은 치즈에서는 양호한 질의 치즈가 많았는데, $7^{\circ},\;13^{\circ},\;21^{\circ}C$에서 3주부터 15주의 숙성기간 중 medium과 sharp flavor 치즈가 생산되었다. 통계분석에 의하면 체다풍미와 caproic acid의 함량에서, 또 체다풍미와 butyric acid, caproic acid 혼합함량 상호관계에서 유의성이 있었다. 적합한 조건을 사용한다면 돼지췌장 리파제는 체다치즈의 숙성을 촉진시키는데 사용 가능한 것으로 사료된다.

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