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Inflammatory Cytokines and Dietary Factors in Korean Elderly with Chronic Disease (만성 질환 노인에서의 면역 성분 양상과 식이예방인자)

  • Park Hee-Jung;Hwang Yu-Jin;Kim Wha-Young
    • Journal of Nutrition and Health
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    • v.39 no.4
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    • pp.372-380
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    • 2006
  • The purpose of this study was to investigate the association between inflammatory cytokines and chronic disease status in Korean elderly. The subjects were 248 elderly people aged over 65 years recruited from Health Center in Seoul. The subjects were classified into 3 groups based on their disease (diabetes, hypertension, and hyperlipidemia) status: subjects with one diagnosed disease of diabetes, hypertension, and hyperlipidemia fall into singular group (n=89), subjects with more than 2 disease into multiple group (n=39), and those with free of the diseases into normal (n=122). Anthropometric and biochemical characteristics, and dietary intakes were assessed. Dietary intakes were surveyed by 24-recall method. The means of IL-2, IL-6, MCP-1 and C3 were not differ among 3 groups. However, when subjects classified into tertiles of IL-6, MCP-1, TNF-$\alpha$ and C3 and frequencies of each fertile were compared, the multiple group showed significantly lower frequencies in lowest fertile than normal group (p<0.05), suggesting higher tendency of inflammatory responses. For hematological values, blood pressure, triglycerides, fasting blood glucose levels were highest in multiple group (p<0.05) compared to other 2 groups. BMI, body fat(kg), and triceps skinfold thickness were also significantly higher in multiple group than in 2 other groups(p<0.05). Moreover, the concentrations of IL-2, IL-6 and C3 were significantly correlated with hematologic values of fasting blood glucose, total cholesterol, LDL-cholesterol, and triglycerides or obesity factors such as triceps skinfold thickness, BMI, and body fat(%). Among singular and multiple group, the subjects with higher intakes for vitamins A, C, and E showed the higher level of IL-2 and the lower level of MCP-1, and C3. In conclusion, blood concentrations of triglycerides and proinflammatory cytokines, blood pressure, obesity parameters (BMI, body fat, triceps skinfold thickness) were higher in multiple group than in normal, but this result strongly suggest that the increasement of the vitamin A, C, and E intakes would modify the cytokine levels to reduce the inflammatory response in the elderly people with chronic diseases.

Naval Warfare and the Development of the Weapon System in History (역사속 해전과 무기체계 발달양상)

  • Kim, Jeong-hyun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.05a
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    • pp.144-150
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    • 2013
  • From ancient times to the present day, naval warfare in history is deeply connected with the rise and fall of countries. This study examines which countries won wars by tracing naval warfare that they had carried out. Seven Cases are traced for the analysis including the battle of Salamis and the Poeni War in the ancient period, the battle of Calais in the medieval and modern periods, the Russo-Japanese War in the modern period, and the Falklands War in the present age. The results show three fundamental characteristics. First, countries that won naval warfare were armed with the state-of-the-art weapon systems and conducted joint operations effectively. Second, countries that fought in the usual ways were defeated by challengers. Third, countries such as Athens, Rome, Britain and the United States ascended to the hegemony by winning major naval warfare and then commanding or controlling the sea at their own free will. Countries defeated in these naval warfare, however, descended to the weak powers. In general, countries that won warfare have a tendency to make light of defeated countries, not to introduce new weapon systems from abroad, and to stick to their traditional ways of fighting. These lessons indicate that the ROK military needs to continue the development of new weapon systems at peacetime. In addition, they show that it needs to focus more on the articulation of military doctrines and training systems so that warriors on the battlefield can fight better.

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A study on the uniqueness of 's hyper-realistic animation style (영화 <아바타>가 보여주는 극사실적 애니메이션 스타일의 특이성 연구)

  • Lee, Youn-H.
    • Cartoon and Animation Studies
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    • s.20
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    • pp.47-61
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    • 2010
  • The Uncanny Valley is a hypothesis introduced by a roboticist, Masahiro Mori. The theory holds that as robots and other facsimiles of humans look and act more human-like, the emotional response from a human spectator to them will become increasingly empathic, until they approach realistic similarity to humans but not quite exactly like them, when those images stop being likable and instead become repulsive and "uncanny." Although the scientific validity of this hypothesis is still debatable, it is true that many spectators has tendency to reject hyper-realistic animation. For that reason, the great success of the recent movie Avatar is remarkable. Computer animations that try to represent humans in hyper-realistic way fall into a paradox: successful result images would look too mundane and unsuccessful ones look "wrong". On top of that, audience would expect from hyper-realistic animation to see same level of acting of live-action films, which is usually not the case. The subtle differences between digital characters and real actors irritate spectators and hinder them in absorbtion. The biggest difference between Avatar and other hyper-realistic animation is the referent of their representation. While Avatar pursues a similar hyper-realistic visual style, the referents of the representation shown in this movie are totally alien to us thus impossible to compare with the real counterparts. Unlike characters in other hyper-realistic animations who had to fight an uphill battle with great actors in real life, those in Avatar have criteria of their own. That is why this movie can be free from the dreadful valley and let the audience absorb into the spectacle.

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Epidemiological surveys of an outbreak of false positive classical swine fever in Gyeongbuk province (의사 돼지콜레라 발생농장 역학조사)

  • Park, No-Chan;Cho, Kwang-Hyun;Kim, Young-Hoan;Kim, Soon-Tae;Kim, Sung-Kuk;Park, In-Hwa;Cho, Min-Hee;Oh, Gang-Hee;Son, Jae-Kweon;Jyeong, Jong-Sik
    • Korean Journal of Veterinary Service
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    • v.26 no.2
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    • pp.163-184
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    • 2003
  • This study was conducted to survey the farm which suffered from disease similar to classical swine fever(CSF) in Gyeongbuk province. Clinical signs appeared first in a few number of growing pigs which showed specific signs of diarrhea, depression, sleepiness, and reluctance to get up or to eat. Younger piglets may have appeared chilled, shiver and huddle together. As the disease progresses the affected pig's skin went red and purple. In histopathological signs, there were many haemorrhages throughout the body and larger haemorrhages in some organs such as lymph nodes. And there is a precipitous fall in the number of circulating leukocytes in the blood. In spite of insisting of farmer which did not vaccinate to classical swine fever, significant antibody production was detected in these affected pigs at enzyme-linked immuonsorbent assay. According to the above results at first glance, these affected pig suspected with CSF in clinical signs and histopathological lesions only. Because the symptoms and post-mortem picture were very similar to CSF, these false positive results would have been dangerous to diagnostician. But by reverse transcriptase polymerase chain reaction(RT-PCR) and comparative nucleotide sequence analysis, the disease was correctly diagnosed with post-weaning multisystemic wasting syndrome(PMWS) and porcine reproductive and respiratory syndrome(PRRS) compoundly. And the antigen which were detected the lesion similar to CSF virus, was confirmed with LOM vaccine strain of CSF. In most national CSF eradication program and in countries which are free of the CSF virus, vaccination against CSF is not practiced and generally is not allowed. But now in Korea, routine vaccination is practiced because of outbreaking the CSF repeatedly. When CSF is diagnosed the whole herd and other in contact animal are slaughtered continuously.

A Study on Chloride Binding Capacity of Various Blended Concretes at Early Age (초기재령에서 각종 혼합콘크리트의 염소이온 고정화능력에 관한 연구)

  • Song, Ha-Won;Lee, Chang-Hong;Lee, Kewn-Chu
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.12 no.5
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    • pp.133-142
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    • 2008
  • This paper studies the early-aged chloride binding capacity of various blended concretes including OPC(ordinary Portland cement), PFA(pulversied fly ash), GGBFS(ground granulated blast furnace slag) and SF(silica fume) cement paste. Cement pastes with 0.4 of a free water/binder ratio were cast with chloride admixed in mixing water, which ranged from 0.1 to 3.0% by weight of cement and different replacement ratios for the PFA, GGBFS and SF were used. The content of chloride in each paste was measured using water extraction method after 7 days curing. It was found that the chloride binding capacity strongly depends on binder type, replacement ratio and total chloride content. An increase in total chloride results in a decrease in the chloride binding, because of the restriction of the binding capacity of cement matrix. For the pastes containing maximum level of PFA(30%) and GGBFS(60%) replacement in this study, the chloride binding capacity was lower than those of OPC paste, and an increase in SF resulted in decreased chloride binding, which are ascribed to a latent hydration of pozzolanic materials and a fall in the pH of the pore solution, respectively. The chloride binding capacity at 7 days shows that the order of the resistance to chloride-induced corrosion is 30%PFA > 10%SF > 60%GGBFS > OPC, when chlorides are internally intruded in concrete. In addition, it is found that the binding behaviour of all binders are well described by both the Langmuir and Freundlich isotherms.

Shoulder Arthrodesis in Brachial Plexus Injury Patient (상완신경총 손상 환자에서 시행한 견관절고정술)

  • Han, Chung-Soo;Chung, Duke-Whan;Lee, Jae-Hoon;Jeong, Bi-O;Park, Hyun-Chul;Kim, Jin-Young;Song, Jong-Hoon;Seo, Jae-Wan
    • Archives of Reconstructive Microsurgery
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    • v.18 no.2
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    • pp.55-61
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    • 2009
  • Purpose: To analyze the clinical and radiologic results of the shoulder arthrodesis in brachial plexus injury patients with flail upper extremity. Material and Method: From Aug 1978 to April 2008, 29 shoulders in 29 patients with brachial plexus injury with shoulder fusion, we evaluated 20 shoulders in 20 patients, more than 1 year follow up. The average follow-up period was 6.45years (range: 1year~24years). There were 13 men and 7 women, and the mean age at the time of trauma was 32.0years(2~65 years). The type of injury was a motorcycle accident in 11 patients, in car accident in 5, pedestrian accident in 3, and fall from a height in 1. The lesion of injury was root and trunk in 1 patient, trunk and cord in 1, trunk in 18. Surgery was performed on the whole arm type paralysis in 12 patients, lower arm type paralysis in 8 patients. The preoperative visual analog scale score was 8.7(7~10). When the trapezius and serratus anterior muscle were in function, operation was performed. 18 patients were processed to the additional operation. Gracilis free flap in 6 patients, neurotization in 3, Steindler flexor plasty in 6, and tendon transfer in 3 were performed. Fixation was conducted with cancellous screws in 13 patients, Knoles pins in 5, and cancellous screws and Knoles pins in 2. The position of the arthrodesis at operation was $28.5^{\circ}$($20~45^{\circ}$) in abduction, $30.3^{\circ}$($20~45^{\circ}$) in flexion, and $30.8^{\circ}$($20~40^{\circ}$) in internal rotation. Result: The follow up visual analog scale score was 3.4(0~7). Postoperatively, shoulder spica cast was applied for 15.3weeks(8-20weeks). The median time to bony union was 17.7weeks(9~28weeks). Average range of motion was $32.0^{\circ}$($15~40^{\circ}$) of abduction, $24.0^{\circ}$($10~40^{\circ}$) of flexion, and $18.5^{\circ}$($10~30^{\circ}$)of internal rotation. Conclusion: The shoulder fusion in brachial plexus injury patients is one of the good methods to relieve pain, improve the function and stabilize the flail shoulder joint.

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Effects of GA3 and Alternating Temperature on Breaking Bud Dormancy of Panax ginseng C. A. Meyer Seedling (인삼 묘삼 휴면 조기타파에 미치는 GA3 및 변온 처리 효과)

  • Kim, Dong Hwi;Kim, Young Chang;Bang, Kyong Hwan;Kim, Jang Uk;Lee, Jung Woo;Cho, Ick Hyun;Kim, Young Bae;Son, Seung Woo;Park, Jong Bae;Kim, Kee Hong
    • Korean Journal of Medicinal Crop Science
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    • v.23 no.5
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    • pp.379-384
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    • 2015
  • Background : Considerable time and effort is required to develop new Panax ginseng varieties. Ginseng breeders have been developing techniques to shorten the breeding cycle to resolve this problem. In this study, we investigated the effects of adding $GA_3$ and alternating temperature (AT, $2^{\circ}C{\rightarrow}-2^{\circ}C{\rightarrow}2^{\circ}C$) on breaking bud dormancy in the varieties (Chungsun and Sunun) of ginseng root. Methods and Results : The $GA_3$ soaking treatment and AT were applied to one year old roots, which greatly accelerated the emergence of new buds. In one year old roots, new buds emerged from the 4th day post transplanting and after breaking dormancy with $GA_3$ and AT treatments. The emergence of new buds was completed within two weeks. The rate of bud emergence for Chungsun was 60% - 98% over 15 - 60 days after the AT and $GA_3$ treatments. The emergence rate of Sunun was 46% - 92%. Normal growth of the ginseng seedling was observed in spite of the early breaking of bud dormancy by combined $GA_3$ and AT treatments. Conclusions : $GA_3$ and AT treatments shortened the dormancy period and facilitated the stable emergence of ginseng seedlings. However, some plants suffered deformities and early sprouting owing to the combined $GA_3$ and AT treatments. Early sprouting was free from dormancy after leaf fall from the of aerial part of the plant.

Preparation of PES Hollow Fiber Membranes and Their $O_2/N_2$ Permeation Properties (폴리이서설폰 중공사막의 제조 및 $O_2/N_2$ 투과특성)

  • Park, Sung-Ryul;Chang, Bong-Jun;Ahn, Hyo-Seong;Kim, Dong-Kwon;Kim, Jeong-Hoon
    • Membrane Journal
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    • v.21 no.1
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    • pp.62-71
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    • 2011
  • Highly enriched oxygen is used in energy-efficient combustion due to decreased non-flammable nitrogen, while high purity nitrogen is used for explosion proof in the LNG ships and keeping the freshness of green stuffs. Membrane technology can be used in these $O_2$ and $N_2$ generation with low energy consumption. In this study, PES was used as a membrane material and 1-methyl-2-pyrollidone (NMP) and acetone were employed as a good solvent and nonsolvent addictive (swelling agent to PES), respectively. Dope solutions were prepared by changing the content of acetone (0, 6.5, 15, 25, 31.5 wt%) in 37 wt% PES solutions. Hollow fiber spinning was performed at 0~10 cm of air-gap distances for each dope solution. $O_2/N_2$ selectivity and permeability were investigated by comparing of hollow fibers coated or not by silicons. $O_2/N_2$ selectivity increased and permeance of $O_2$ and $N_2$ decreased with increasing air-gap height independently of acetone addictions. Optimized PES hollow fibers were obtained with 37/6.5/56.5 wt% PES/acetone/NMP dope solution and 10 cm air-gap, which showed 7.3 of $O_2/N_2$ selectivity and 4.3 GPU of $O_2$ permeability after silicon coating.

An Empirical Study on M&A (M&A에 관한 실증연구)

  • 김동환
    • Proceedings of the KAIS Fall Conference
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    • 2001.05a
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    • pp.62-65
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    • 2001
  • 1997년과 1998년 4월 1일자의 M&A제한규정이었던 증권거래법 제200조의 철폐와 적대적 M&A의 전면허용 그리고 외국자본의 투자제한의 간소화 등 규제완화조치와, 향후 외국인에 대해서 100%까지 주식을 매입할 수 있는 적대적 M&A가 허용될 것으로 보여 우리나라에서도 M&A활동이 보다 본격화 될 것으로 전망되고 있다. 우리나라에서는 1980년대부터 M&A에 대한 관심과 연구가 시작되면서 지금까지 기업합병ㆍ인수의 동기와 효과에 대해서 많은 연구가 이루어져 왔다. 지금까지의 연구내용은 대부분 기업의 M&A동기는 시너지효과를 얻기 위함이며, 또한 공시정보가 합병공시일 전후동안에 주가수익율에 반영되어 합병 당사기업의 주주의 부에 영향을 미치는지의 주가변화 유무에 국한된 것이었다. 또한 1985년부터 1991년 초 사이에 이루어졌던 연구는 당시 국내 M&A 환경이 매우 열악하고 극히 제한된 비정상적인 자본시장 상황 하에서 이루어진 사례에 의한 연구이었기 때문에 연구결과의 문제점과 한계성이 있었고, 실효성 측면에서도 다소 미흡하였다고 할 수 있다. 우리나라 M&A의 성장발전과정을 크게 2단계로 분류한다면, 제1단계는 1975년부터 시작하여 1990년까지로써 이 기간동안의 M&A환경은 그 여건조성과 성숙준비단계였으며, 제2단계인 1990년 초부터 비로소 선진국형 시장경제원리에 근거한 보다 경쟁적이고 자율적인 M&A 시장구조가 형성되면서 활성화 단계로 진입하였다고 볼 수 있을 것이다. 본 연구의 주된 목적은 1990년부터 1996년 사이에 이루어진 상장기업의 M&A 사례를 표본으로 하여 한국에서의 기업합병과 기업인수(주식취득)가 기업가치에 미치는 영향을 구명하는데 있다. 이를 위하여 먼저, M&A 당사기업의 합병성과 발생과 차이 유무를 주가수익율을 측정하여 실증분석하고 다음으로 M&A에 따른 시너지의 잠재적 원천이 어디에 있는지 재무성과분석을 통해서 이를 실증하는데 목적이 있다.PA-designated retailers ("sellers") must accept end-of-life items returned to them by the consumers. At the local level, Taipei City implements a pay-as-you-throw program, whereby citizens pay waste collection and treatment fees through the purchase of special trash bags approved by the Taipei City Government. However. recyclables that are separated by citizens are collected free-of-charge by the City. Taichung City and Kaohsiung City, on the other hand, enforce mandatory sorting schemes, whereby citizens face penalties if they don't separate recyclables from the trash before pick-up. These programs have resulted in a significant reduction in municipal waste. Per capita waste collected per day has dropped from 1.143 kg in 1997 to 0.978 kg in 2000. Targeting a 10% recycling rate for municipal waste in 2001. EPA plans to research and develop new recycling techniques, expand the scope of producer responsibilities, and strengthen existing mu

The Effects of Pilates Exercise on Static and Dynamic Balance in the Elderly

  • Park, Ji-Hye;Lee, Joong-Sook;Yang, Jeong-Ok;Lee, Bom-Jin;Bae, Kang-Ho;Shin, Jin-Hyung
    • Korean Journal of Applied Biomechanics
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    • v.26 no.4
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    • pp.397-405
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    • 2016
  • Objective: Pilates is a low/mid-intensity exercise that can be easily performed by elderly individuals as it is an individual body-oriented exercise. It is also a cardio workout that can be performed anywhere to develop strength and flexibility. Therefore, we investigated the effects of 8 week Pilates program on the balancing ability of elderly individuals. Method: The research participants were selected from elderly residents in B city. Ten individuals voluntarily signed an agreement to undergo free measurements as well as to participate in the workout program. (Height: $157.1{\pm}11.9cm$, Weight: $61.7{\pm}8.0kg$). The Pilates exercise was performed 60 minutes a day, three times a week for a total of eight weeks. The measurement variables used to test balance were the vestibular test, 5 m habitual and maximum walk test and 3 m tandem walk test. A series of paired t-test were conducted using IBM SPSS Statistics 23.0 to analyze all the research data collected in order to determine the balance ability of the participants before and after the Pilates program. Additionally, the statistically significant level for all analysis was set to ${\alpha}=.05$. Results: In the vestibular test, some meaningful changes were observed in the length envelope area (ENV) while standing on one foot, but there were no significant differences in the ENV, rectangle(REC), root mean square, and total length. Results also revealed that statistically significant differences existed in the 5 m habitual and maximum walk test, as well as the 3 m tandem walk test. Conclusion: To summarize the findings, the 8 week Pilates program employed in this study significantly improved the dynamic balance of the elderly participants. Thus, elderly individuals that frequent perform Pilates are expected to enjoy positive benefits such as increased balance and fewer falling accidents.