• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.25 no.10
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• pp.685-691
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• 2015

In this work, to identify effective parameter for performance of piezoelectric jetting dispenser, experimental investigation is carried out based on design of experiment. After preparing jetting dispenser using two stack-type piezoelectric actuators, basic working principle of the jetting dispenser is described. Eight operating conditions are chose as main factors and it is assumed that each factor has two levels. To reduce number of experiments for performance evaluation, the experimental sets are designed based on factional factorial design method. Experimental setup is established and the weight of single dot is measured by using precision scale. The main and interaction effects of factors are analyzed using commercial statistical program and optimal operating condition for small amount and small variation of weight of dispensed single dot are determined.

• Analytical Science and Technology
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• v.20 no.5
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• pp.370-382
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• 2007

In this study, solid-phase microextraction (SPME) technique using GC/FID was studied as a possible alternative to liquid-liquid extraction for the analysis of EGBE, DGBE, DBM and TGME in water, and an optimization condition of trace analysis of EGBE, DGBE, DBM and TGME using the factorial design was described. Experiments used a fractional factorial design method followed by central composite design allowing optimization of a number of factors as well as statical analysis of results. The response surface analysis showed that the extraction efficiency can be described by a second-order polynomial equation in which the salts concentration, extraction temperature, extraction time and sonication time are the major influences. Using DOE, a new data-dependent method was developed that improved the quantity of confidently analyzed EGBE, DGBE, DBM and TGME in water samples.

• KSBB Journal
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• v.24 no.1
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• pp.30-40
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• 2009

Statistical optimization of the production medium was carried out in order to find an optimal medium composition in itaconic acid fermentation process. Itaconic acid utilized in the manufacture of various synthetic resins is a dicarboxylic acid biosynthesized by fungal cells of Aspergillus terreus in a branch of the TCA cycle via decarboxylation of cis-aconitate. Through OFAT (one factor at a time) experiments, six components (glucose, fructose, sucrose, soluble starch, soybean meal and cottonseed flour) were found to have significant effects on itaconic production among various carbon- and nitrogen-sources. Hence, using these six factors, interactive effects were investigated via fractional factorial design, showing that the initial concentrations of sucrose and cottonseed flour should be high for enhanced production of itaconic acid. Furthermore, through full factorial design (FFD) experiments, negative effects of $KH_2PO_4$ and $MgSO_4$ on itaconic acid biosynthesis were demonstrated, when excess amounts of the each component were initially added. Based on the FFD analysis, further statistical experiments were conducted along the steepest ascent path, followed by response surface method (RSM) in order to obtain optimal concentrations of the constituent nutrients. As a result, optimized concentrations of sucrose and cottonseed flour were found to be 90.4g/L and 53.8g/L respectively, with the corresponding production level of itaconic acid to be 4.36 g/L (about 7 fold higher productivity as compared to the previous production medium). From these experimental results, it was assumed that optimum ratio of the constituent carbon (sucrose) and nitrogen (cottonseed flour) sources was one of the most important factors for the enhanced production of itaconic acid.

• Proceedings of the KSME Conference
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• 2007.05b
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• pp.2666-2671
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• 2007

This work presents microchannel heat sink shape optimization procedure using Kriging method. Design variables relating to microchannel width, depth and fin width are selected, and thermal resistance has been taken as objective function. Design points are selected through a three-level fractional factorial design of sampling method. Navier-Stokes and energy equations for laminar flow and conjugate heat transfer are solved at these design points using a finite volume solver. Solutions are carefully validated with experimental results. Using the numerically evaluated objective function, a surrogate model (Kriging) is constructed and optimum point is searched by sequential quadratic programming. The process of shape optimization greatly improves the thermal performance of microchannel heat sink under constant pumping power.

• 한국생물공학회:학술대회논문집
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• 2003.04a
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• pp.153-156
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• 2003

The MRS medium is widely used as an optimized medium for the growth of Lactobacillus spp. and also used for the growth of Leuconostoc spp. Leuconostoc mesenteroides shows quite different physicochemical properties compared to Lactobacilli spp. and it is one of the major strain of kimchi fermenting microorganisms with its usefulness in our traditional foods and availability in biotechnology in the future, specifically tailor-made medium is necessary for the growth of Leuconostoc mesenteroides. Sequential experimental designs (Plackett-Burman, fractional factorial, steepest ascent, central composite design and response surface methodology) were introduced to optimize and improve the Leuconostoc medium. Fifteen medium ingredients were investigated and fructose, sodium acetate and ammonium citrate were determined to give a critical and positive effect for cell-growth. The yield of biomass using the optimal medium was improved more than that of the MRS medium and the result of fed-batch culture showed the capability of the improvement in cell mass similar to the E.coli system.

• Journal of Agricultural Extension & Community Development
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• v.16 no.3
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• pp.615-641
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• 2009

This study aims to develop Semangum tourism package that can be most suitable for the tourist. The data were obtained by a survey carried out between August, 17 and August, 24, 2009 with a sample of latent tourist of Semangum. Conjoint analysis has been used to estimate the relative importance of attributes. Four main attributes and two or three attributes levels for each determinant were chosen for conjoint analysis. Eleven model package were made using fractional factorial design, and presented to the latent tourist, who were asked to reply in order of their like. Results show that the most important attributes for tourist were in order of cost, connected tourism, accommodation and report activity.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.10
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• pp.2509-2517
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• 1993

Lapping is a very complicated and random process resulting from the variation of abrasive grains in its sizes and shapes and from the numerous factors having an effect on the process quality. Thus it needs to be analyzed by experimental method rather than by theoretical method to obtain the relative effects of factors quantitatively. In this study, cylindrical lapping experiment designed by Taguchi's L8 orthogonal array was performed and analyzed by Yates' ANOVA table. As a result, effective factors and interaction effects were identified and discussed. Also the optimal factor combination to obtain the largest improvement of surface roughness was selected and confirmatory experiments were peformed.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.31 no.9
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• pp.733-740
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• 2007

Microchannel heat sink shape optimization is performed using Kriging method. Design variables relating to microchannel width, depth and fin width are selected, and thermal resistance has been taken as objective function. Design points are selected through a three-level fractional factorial design of sampling method. Navier-Stokes and energy equations for laminar flow and conjugate heat transfer are solved at these design points using a finite volume solver. Solutions are carefully validated with experimental results. Using the numerically evaluated objective function, a surrogate model (Kriging) is constructed and optimum point is searched by sequential quadratic programming. The process of shape optimization greatly improves the thermal performance of microchannel heat sink under constant pumping power.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.20 no.6
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• pp.521-527
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• 2010

This article presents a method to calculate the sound radiation of transmission gearbox housing by using Helmholtz integral. Rayleigh integral is used to verify the method. Half-space radiation is considered because the actual gearbox housing is on hard place like concrete. For optimization, orthogonal array is used as a fractional factorial design method. Sound Radiation is calculated with simple source like plate and sphere shape, then actual gearbox BEM model is applied to the method.

• Journal of Magnetics
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• v.15 no.3
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• pp.132-137
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• 2010

Plasma etching of $SiO_2$ contact holes was statistically analyzed by a fractional factorial experimental design. The analysis revealed the dependence of the etch rate and DC self-bias voltage on the input factors of the magnetically enhanced reactive ion etching reactor, including gas pressure, magnetic field, and the gas flow rates of $CHF_3$, $CF_4$, and Ar. Empirical models of the DC self-bias voltage and etch rate were obtained. The DC self-bias voltage was found to be determined mainly by the operating pressure and the magnetic field, and the etch rate was related mainly to the pressure and the flow rates of Ar and $CHF_3$.