• Journal of Science Education
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• v.39 no.1
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• pp.113-131
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• 2015

The purpose of this study was to analyze the interactive patterns between teacher and students in middle school earthh science classroom, identify difference of discourse types between earthh science classes taught by majored and non-majored teacher, find the relationship between the discourse pattern and the type of teachers' questions. For that purpose, the participants in this study included four teachers and their students of three middle schools in Seoul. The data consisted of two parts. First, we categorized interaction between teacher and students into the types of discourses by the use of Mortimer and Scott's analytical framework(2003). Second, we classified teachers' questions into four different types of question based on MNeill & Pimentel's classification scheme(2009) to examine for the relationship between the discourse pattern and the type of teachers' questions. As a result, all teachers used interactive/authoritative discourse most in middle school earth science class. Therefore, there was more authoritative discourse to non-majored teacher in comparison with majored teacher. And study demonstrated that the discourse pattern was more related to feedback about student's response rather than the type of teachers' question. In other words, the dialogic discourse showed up more frequently when the teacher used delayed feedback with positive and accepting attitude.

• Journal of Science Education
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• v.41 no.1
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• pp.16-35
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• 2017

This study attempted to investigate the relationship among engineering students' creativity, engineering education accreditation, gender, and academic year. To be specific, fist, we examined the validity and reliability of the instrument for measuring engineering students' creativity by conducting Rasch analysis. Second, we compared level of creativity in terms of gender, academic year, and engineering education accreditation by using three-way ANOVA. Third, correlations among four constructs of creativity were examined. Fourth, latent classes with respect to creativity within the participants were identified using polytomous latent class analysis (poLCA). Data were collected from 2098 engineering students by using instrument for measuring four different constructs (creative cognition, creative tendency, collaboration, environment). By using Rasch analysis, validity and reliability of instrument for measuring creativity were confirmed. And the results of three-way ANOVA showed that there were significant difference in creativity in terms of gender. Female students showed the low level of creativity compared with male students. Also there were significant difference in creativity except creative cognition factor in terms of academic year. But there were no significant difference in creativity between students who participated engineering education accreditation program and the others. All constructs of creativity were significantly correlated with each others. Lastly, poLCA results showed that there were three distinct subgroups within engineering students in terms of the level of creativity. In the subgroup with low creativity, there were more female and first year students. Based on these findings, we discussed education for engineering students' creativity.

• School Mathematics
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• v.15 no.3
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• pp.619-632
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• 2013

One area where research is especially needed is their elaboration process and how they elaborate their idea as a group in a mathematical board game re-creation project. In this research, this process was named 'Mathematical Elaboration Process'. The purpose of this research is to understand how the gifted children elaborate their idea in a small group, and which idea can be chosen for a new board game when they are exposed to a project for making new mathematical board games using the what-if-not strategy. One of the gifted children's classes was chosen in which there were twenty students, and the class was composed of four groups in an elementary school in Korea. The researcher presented a series of re-creation game projects to them during the course of five weeks. To interpret their process of elaborating, the communication of the gifted students was recorded and transcribed. Students' elaboration processes were constructed through the interaction of both the mathematical route and the non-mathematical route. In the mathematical route, there were three routes; favorable thoughts, unfavorable thoughts and a neutral route. Favorable thoughts was concluded as 'Accepting', unfavorable thoughts resulted in 'Rejecting', and finally, the neutral route lead to a 'non-mathematical route'. Mainly, in a mathematical route, the reason of accepting the rule was mathematical thinking and logical reasons. The gifted children also show four categorized non-mathematical reactions when they re-created a mathematical board game; Inconsistency, Liking, Social Proof and Authority.

• Journal of The Korean Association For Science Education
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• v.35 no.2
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• pp.289-301
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• 2015

This study noted that elementary school students were unable to accurately comprehend the principles of moon phase changes and that teachers themselves lacked a full understanding of it as well. Therefore, this study classifies conception types through 161 5th grade respondents and suggests how to change students' conception types through the use of reconstructed teaching and learning materials (that have been developed in existing studies). It verified the changes in the learning achievement of 129 5th grade respondents and analyzed how to think about reconstructed teaching and learning materials through four teacher respondents and four 5th grade respondents from the same study. The results of this study are as follows: First, the conception types on moon phase changes were classified into C and W types. W types consisted of W1, W2, W3, W4, and W5 types. Students had difficulty in understanding the principles of a waxing crescent moon and first quarter phase changes. Second, the group taking classes, which implemented reconstructed teaching and learning materials, showed greater improvement in learning achievement posttest and long-term tests compared to those who have not. Finally, teachers and students reacted positively to the reconstructed teaching and learning materials as shown in exit survey results. In conclusion, it is suggested that teachers are better off utilizing reconstructed teaching and learning materials so that elementary school students may fully understand the principles of moon phase changes rather than just memorizing the results.

• Bulletin of the Korean Chemical Society
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• v.30 no.5
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• pp.1152-1156
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• 2009

Silent information regulator 2 (Sir2) or sirtuins are NAD(+)-dependent deacetylases, which hydrolyze the acetyllysine residues. In mammals, sirtuins are classified into seven different classes (SIRT1-7). SIRT1 was reported to be involved in age related disorders like obesity, metabolic syndrome, type II diabetes mellitus and Parkinson’s disease. Activation of SIRT1 is one of the promising approaches to treat these age related diseases. In this study, we have used HipHop module of CATALYST to identify a series of pharmacophore models to screen SIRT1 enhancing molecules. Three molecules from Sirtris Pharmaceuticals were selected as training set and 607 sirtuin activator molecules were used as test set. Five different hypotheses were developed and then validated using the training set and the test set. The results showed that the best pharmacophore model has four features, ring aromatic, positive ionization and two hydrogen-bond acceptors. The best hypothesis from our study, Hypo2, screened high number of active molecules from the test set. Thus, we suggest that this four feature pharmacophore model could be helpful to screen novel SIRT1 activator molecules. Hypo2-virtual screening against Maybridge database reveals seven molecules, which contains all the critical features. Moreover, two new scaffolds were identified from this study. These scaffolds may be a potent lead for the SIRT1 activation.

• Archives of Pharmacal Research
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• v.29 no.8
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• pp.633-644
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• 2006

In last couple of decades the use of natural compounds like flavonoids as chemopreventive agents has gained much attention. Our current study focuses on identifying chemopreventive flavonoids and their mechanism of action on human prostate cancer cells. Human prostate cancer cells (PC3), stably transfected with activator protein 1 (AP-1) luciferase reporter gene were treated with four main classes of flavonoids namely flavonols, flavones, flavonones, and isoflavones. The maximum AP-1 luciferase induction of about 3 fold over control was observed with $20\;{\mu}M$ concentrations of quercetin, chrysin and genistein and $50\;{\mu}M$ concentration of kaempferol. At higher concentrations, most of the flavonoids demonstrated inhibition of AP-1 activity. The MTS assay for cell viability at 24 h showed that even at a very high concentration $(500\;{\mu}M)$, cell death was minimal for most of the flavonoids. To determine the role of MAPK pathway in the induction of AP-1 by flavonoids, Western blot of phospho MAPK proteins was performed. Four out of the eight flavonoids namely kaempferol, apigenin, genistein and naringenin were used for the Western Blot analysis. Induction of phospho-JNK and phospho-ERK activity was observed after two hour incubation of PC3-AP1 cells with flavonoids. However no induction of phospho-p38 activity was observed. Furthermore, pretreating the cells with specific inhibitors of JNK reduced the AP-1 luciferase activity that was induced by genistein while pretreatment with MEK inhibitor reduced the AP-1 luciferase activity induced by kaempferol. The pharmacological inhibitors did not affect the AP-1 luciferase activity induced by apigenin and naringenin. These results suggest the possible involvement of JNK pathway in genistein induced AP-1 activity while the ERK pathway seems to play an important role in kaempferol induced AP-1 activity.

• Journal of Digital Convergence
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• v.11 no.10
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• pp.737-746
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• 2013

This research aim is to investigate the rate and pattern of re-using the four-digit personal identification numbers(PINs). 1313 types of PINs were observed by 224 students who took this author's classes from last 2006 to 2011 at A-university. Some students used PINs as few as 3-4 and as many as 12-13. The average is 5.86 per person. The rates of re-using PINs were calculated by each student. 87%(195/224) of students reused PINs and 64% of them reused with just only one type of PINs, 20% reused with 2 types, and about 3% reused with 3-4 types. With respect to PINs, 884 out of the total 1313 PINs were reused, that is around 64.3%. In a broad sense, a pair of slight modification of PINs were also observed, that is, new PINs were partly matched in position or size of numbers of previous PINs. And if the reuse rate falling under the slight modification of PINs, 10.4% is added, about 75% of the PINs were reused in a broad sense. The re-using rate of male students is higher than the one of female students. This paper's results may provide to make plan for hacks of passwords.

• Journal of the Korean Chemical Society
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• v.64 no.5
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• pp.277-290
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• 2020

In this study, four gifted students in the second year of middle school at Gifted Education Center of the National University in Jeollanam-do were surveyed students' perceptions of the effectiveness of science class using science writing heuristic in terms of metacognition and the goals of the 2015 revised science curriculum. Through questionnaires and interviews with gifted science students, science gifted students recognized that the science class using science writing heuristic had a positive effect on the four subdomains (planning, monitoring, control, and evaluation) of metacognition. For this reason, the science gifted students presented self-directed experience in designing experiments, continually checking the collected experimental data, feedback process, and reflecting experience in preparing conclusions. Science gifted students recognized that science class using science writing heuristic had a positive effect on the goals of the 2015 revised science curriculum(attitudes, inquiry, knowledge, Science·Technology·Society(STS), and the enjoyment and usefulness of science learning) that correspond to through inquiry science writing lessons. For this reason, the science gifted students presented self-directed inquiry experiences, continual inquiry experiences on the same subject, thinking process at each stage of inquiry, learning experiences through inquiry, experience of the whole inquiry process, and inquiry of phenomena closely related to real life. Therefore, for the effective science class, it is necessary to apply the characteristics of science class using science writing heuristic which is responded by science gifted students to general science class as well as science gifted class later.

• Journal of Korean Home Economics Education Association
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• v.18 no.2 s.40
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• pp.47-62
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• 2006

This research was conducted to find out price change of education service. Consumer Price Index annual series data in Korea National Statistical office from 1990 to 2004 were used for analysis. First, education price indexes showed an average annual increase of 7.3% during the last 15 years (1990-2004), marking the highest increase among items in the CPI basket. The average annual increase in tuition fees and other fees, expenditure classes of education price. has been 7.5% and 6.0%, respectively. Secondly, an average increase in tuition fees for two-year college was higher, followed by tuition fees for kindergarten, private four-year college, national four-year college and secondary schools. An average increase in primary school textbook costs was higher in the category of 'other fees' followed by junior high school textbook costs, junior high school supplementary book costs and home delivery supplementary book costs Thirdly, there were no differences in price changes of secondary school textbooks, junior high school supplementary books, high school supplementary books among 16 locations. An average increase in after-school education (selective subjects) for college entrance examination was higher in Gwangju but lower in Seoul, compared with other cities. An average of 7% difference was seen annually among regions. When the year 2000 was considered as 100, the most significant gains were seen in Kwangju at 80% and Gangwon at 57%. An increase in after-school education (all subjects) for college entrance examination was higher in South Cholla Province but lower in North Gyeongsang Province. An increase in after-school education (all subjects) for college entrance examination was higher in South Cholla Province but lower in North Gyeongsang Province. An average of 7% difference was seen annually in the annual increase. When the year 2000 was considered 100, most significant increase was seen in Busan and South Gyeongsang Province at 37% and Jeju Island at 34%.

• Journal of Korean Society on Water Environment
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• v.22 no.3
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• pp.431-436
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• 2006

This study was conducted in the summer of 2005 in Shindong-myeon, Chuncheon-si, Gangwon-do to assess the quality of drinking water and to evaluate their potential pollutants. Ninety four water samples were collected from three classes of water supplies such as simple piped water, supplied own water and others (Supplied local water). Most residents used simple piped water (72.63%). 31.25% residents thought the water quality was bad and landfill was the main source of pollution that affected water quality. To correspond this perception, water quality was measured according to Drinking Water Quality Standard. The general bacteria, coliforms, and $NO_3-N$ exceeded the standard but the water qualities in these four areas were suitable for Drinking Water Quality Standard. The simple piped water showed low mean concentration of excess rate compared to supplied own piped water except general bacteria. Hardness, pH, and $NO_3-N$ showed significantly higher effects on drinking water quality. To evaluate the effect of effluent from landfill, water quality was measured according to distance and altitude. However, there was no effect of landfill effluent. To find out the effect of rainfall, we compared water quality of the year 2003 with that of 2005. The result showed significant differences in hardness and $NO_3-N$ concentration. This study confirmed that $NO_3-N$, coliforms, and general bacteria are main pollutant of water supply in rural community. Therefore, it is necessary to regularly maintain simple piped water supply, supplement sewer facilities, and educate residents about public health risk associated with drinking water in rural area.