• The Korean Journal of Cytopathology
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• v.9 no.1
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• pp.15-20
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• 1998

Mutant form of the p53 gene product is abnormally accumulated in the nuclei of the tumor cells due to prolonged half life, and readily detected by immunohistochemical methods. To determine the positivity rate of p53 in body cavity fluid according the primary site and histological types of tumors and the utility of p53 immunostaining as an adjunct in the diagnosis of malignancy, we reviewed 69 effusions, including pleural effusion, ascitic fluid, and pericardial fluid, that were diagnosed as overt malignancy and 21 effusions of suspicious malignancy, immunohistochemistry was performed on paraffin-embedded cell blocks using a monoclonal antibody to p53 supressor gene product(Clone DO7) and a standard avidin-biotin complex technique with a citrate buffer antigen retrieval solution. The results were as follows; of the 46 pleural effusions with overt malignancy, 22 were immunopositive for p53 protein; of the 21 ascitic fluids with overt malignancy, 5 were positive for p53. Positivity rates according to the primary sites of tumors were 18 of 34(52.9%), 8 of 21(38.1%), 1 of 9(11.1%) cases of the tumors of the lung, GI tract, and ovary, respectively. According to the histologic types of lung cancer, 11 cases(61.6%) were positive out of 18 adenocarcinomas, 2 of 5 large cell undifferentiated carcinomas, and 1 of 2 small cell undifferentiated carcinomas. Of 21 cases of suspicious malignancy, 6 were positive for p53 and all of them(6/6) were confirmed as adenocarcinoma of the lung or GI tract. These findings indicate that p53 immunostaining using paraffin embedded cell block is useful diagnostic and prognostic marker in body fluid cytology although negative immunostaining does not exclude malignancy.

• Korean Institute of Interior Design Journal
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• v.24 no.1
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• pp.160-168
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• 2015

The subject of this research is to analyze the design characteristics of outdoor spaces in Good Design awarded apartment complexes in the past decade. The results are as follows. First, the overall outdoor space design theme, one of the conceptual elements, is focused on both 'nature' and 'story of various subject' that are similar to each other. Second, the case study object with the visual openness, which is secured between apartment blocks, is shown frequently in case box-shaped apartment blocks are arranged in a row. However, in case of Y-shaped block arrangement, the visual openness secured within an apartment complex is considered more important. Third, according to the result of circulation/ inner path element, the most frequently appeared inner path form is a grid pattern with straight path emphasis. While apartment complexes with the parking lot on the ground are only 3 out of 18 cases, it with circulation path for vehicle on the ground level are over 61%. Fourthly, the design characteristic of social space of physical outdoor design appears to be 'central link facility type'. In this case, the central community facilities are more likely to be combined with various functions, such as green, water, and social connection. Fifthly, in case of natural space, most of the apartment cases are shown over 45% green area ratio with wide green and water space provision. Especially, the differentiation is to provide the space where can stimulate a resident's participation.

• Journal of Crop Science and Biotechnology
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• v.11 no.1
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• pp.69-74
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• 2008

This work aimed to evaluate 11 potato families for insect resistance horticultural traits. The families were derived from crosses between introduced insect resistant and adapted genotypes. A randomized complete block design, with three replications was used. The plot consisted of 25 genotypes of a family, summing up to 75 genotypes tested per family. Two susceptible cultivars were included in the experiment as checks. The genotypes were evaluated for insect resistance, tuber yield traits, tuber appearance and tuber skin smoothness. The genetic value for the intensity of insect attack in the leaves and in the tubers was lower(higher resistance) in the 11 families than in the checks. For yield traits, there was no predominant effect among the families regarding the origin of the resistant donor species(Solanum berthaultii and/or S. chacoense). However, there was a large contribution of the C-1485-16-87 recurrent parent in crosses with resistant genotypes for tuber yield and tuber number. In relation to tuber appearance, only the family derived form the C-1485-16-87/ ND140(S. berthaultii) cross did not differ from the checks. had genetic value tuber skin smoothness, it was identified that families derived from S. berthaultii resistant parents showed higher genetic values than the check cultivars. For tuber skin smoothness, the genetic values of the families neither differed significantly from each other nor from the checks.

• Journal of the Korean Institute of Gas
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• v.12 no.4
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• pp.14-20
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• 2008

In this numerical study, the leakage safety of the LNG tank in which is constructed by membrane inner tank-plywood-polyurethane form-plywood-prestressed concrete structures has been presented for four leakage analysis models. The LNG leak criterion of the tank wall with a storage capacity of $200,000\;m^3$ is analyzed based on the thermal resistance technique. This means that if the cryogenic temperature of a leaked LNG is detected at the outer side of the PC wall, it may be leaked through the wall thickness of the tank. The calculated results based on the thermal resistance method between two walls show that the plywood, PUF, and another plywood walls may block the leakage of the leaked LNG even though the strength of these walls is already collapsed by a leaked LNG pressure. But, the leaked LNG may pass the thickness of the prestressed concrete wall for a period of elapsed time even though the PC outer tank supports the leaked LNG pressure. Thus, the PC outer tank may extend the leakage time of a leaked LNG.

• International Journal of Aeronautical and Space Sciences
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• v.18 no.4
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• pp.807-815
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• 2017

For liquid rocket engine(LRE)-based space launch vehicles, longitudinal instability, often referred to as the pogo phenomenon in the literature is predicted. In the building block of system-level task, accurate dynamic modeling of a fluid-filled tank is an essential. This paper attempts to apply the virtual mass method that accounts for the interaction of the vehicle structure and the enclosed liquid oxygen to LOX-filled tanks. The virtual mass method is applied in a modal analysis considering the hydroelastic effect of the launch vehicle tank. This method involves an analysis of the fluid in the tank in the form of mass matrix. To verify the accuracy of this method, the experimental modal data of a small hemispherical tank is used. Finally, the virtual mass method is applied to a 1/8-scale space shuttle external tank. In addition, the LOX tank bottom pressure in the external tank model is estimated. The LOX tank bottom pressure is the factor required for the coupling of the LOX tank with the propulsion system. The small hemispherical tank analysis provides relatively accurate results, and the 1/8-scale space shuttle external tank provides reasonable results. The LOX tank bottom pressure is also similar to that in the numerical results of a previous analysis.

• The Journal of the Korea Contents Association
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• v.20 no.5
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• pp.11-22
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• 2020

The academic credit banking system is an educational system to implement a lifelong learning society. Students who meet the requirements of this system can achieve academic degrees equivalent to those of junior colleges or four-year universities. Credits and degree information of these students are recorded and managed by the central institution. However, this system can cause security problem such as hacking due to centralized management. In this paper, we propose an academic credit banking system which can manage credits and degree information based on blockchain technology. In the proposed system, credits and degree information are stored in block and managed in the public ledger in a permanent manner. Blocks are connected in the form of blockchain on a distributed network to improve security problems such as hacking and manipulation. Also, the efficiency of credit bank management can be increased because the functions of the central institution are distributed to the network participants. The prototype of the proposed system was implemented on the Go-Ethereum platform and experimentally verified the blockchain information among participating organizations using smart contracts.

• Korean Journal of Psychosomatic Medicine
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• v.12 no.2
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• pp.103-121
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• 2004

Conversion disorder and factitious disorder should be ruled out before making diagnosis of malingering. For this work, inspection of patient's behavior along with complete neurological examinations, psychological tests, and meticulous psychiatric interview are necessary. Facial expression test, thermography, dynamometry were failed differentiating conversion disorders to the malingered pain and motor symptoms, however, controlled diagnostic block showed positive result partly in patients with regional or cervical pain syndrome. Chronic pain patients who are related to the process of litigation encounter stressful life situations which lead them into various neurobehavioral and psychosocial complications. Most of suspected malingered patients would not revealed pure form rather mixed with factitious and/or conversion features. At the time of increasing number of chronic patients associated with traffic accidents or industrial injuries who are involved in litigation, psychiatrist are needed sharp eyes and tenacity for evaluating malingering or medically unexplained symptoms.

• Journal of the Korean Institute of Rural Architecture
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• v.20 no.2
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• pp.49-56
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• 2018

The vernacular houses with 田-shaped floor plan at Gangreung have been played important roles in tracing the vernacular living cultures including housing life. But due to the adoption of convenient facilities in vernacular housing lives caused by modernization and urbanization, many changes and transformations have happened at residential space of vernacular houses. This thesis targets to extract basic data to prepare and prevent various problems in process of renovation, extension and function change as installing housing life facilities, and to identify the changes and transformations of them to prepare the proper balances between their original form preservation and residents' convenience living. The results are as follows. The inner wall removal of rooms, the fuel change of cooking and heating, the leveling change of kitchen floor made possible the sedentary lifestyles. And its residential rooms were transformed from two row to one row by inner wall removal, the fuel heating change, the heating method change and the heat insulating materials. The residential extension materials were changed from the traditional materials such as soil, wood, etc to the modern materials such as cement block or brick, sandwich panel, etc. And the modern materials were used and attached to widen residential spaces to the vernacular house because of the easiness of execution. So, it is necessary for 田-shaped floor plan vernacular house owners to distribute printed execution guide book to prevent and minimize the various problems to be shown by extension, renovation and function change.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.1405-1408
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• 2005

An embedded system has been applied to many fields including households and industrial sites. In the past, user interface products with simple functions were commercialized .but now user demands are increasing and the system has more various applicable fields due to a high penetration rate of the Internet. Therefore, the demand for embedded system is tend to rise In this paper, we Implementation of an embedded system for image tracking. This system is used a fixed IP for the reliable server operation on TCP/IP networks. A real time broadcasting of video image on the internet was developed by using an USB camera on the embedded Linux system. The digital camera is connected at the USB host port of the embedded board. all input images from the video camera is continuously stored as a compressed JPEG file in a directory at the Linux web-server. And each frame image data from web camera is compared for measurement of displacement Vector. That used Block matching algorithm and edge detection algorithm for past speed. And the displacement vector is used at pan/tilt motor control through RS232 serial cable. The embedded board utilized the S3C2410 MPU Which used the ARM 920T core form Samsung. The operating system was ported to embedded Linux kernel and mounted of root file system. And the stored images are sent to the client PC through the web browser. It used the network function of Linux and it developed a program with protocol of the TCP/IP.

• Journal of Acupuncture Research
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• v.24 no.6
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• pp.137-148
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• 2007

Objectives : Following central nervous system (CNS) injury, inhibitory influences at the site of axonal damage occur. Glial cells become reactive and form a glial scar, know as gliosis. As well,myelin debris such as MAG inhibits axonal regeneration. Astrocyte-rich gliosis relates to up-regulation of GFAP and CD81, and eventually becomes a physical and mechanical barrier to axonal regeneration. It is postulated that when the astrocytic reaction is absent, regeneration of axons can occur. It was reported that treatment with anti CD81 antibodies enhanced functional recovery in rats with spinal cord injury. Methods : MAG is one of several endogenous axon regeneration inhibitors that limit recovery from central nervous system injury and disease. It was reported that molecules which block such inhibitors enhanced axon regeneration and functional recovery. Results : In this current study, the author investigated the effect of the water extract of Ginseng Radix on the regulation of CD81, GFAP and MAG which increases when gliosis occurs. MTT analysis was performed to examine cell viability, and cell based ELISA, Western Blot and PCR were used to detect the expression of CD81, GFAP and MAG. Immunohistochemistry was also performed to confirm in vivo. Conclusions : We observed that Ginseng Radix significantly down-regulates the expression of CD81, GFAP and MAG by means of cell based ELISA, Western Blot and PCR. In immunohistochemistry, expression of CD81, GFAP and MAG also decreased. Taken together, these results suggest that Ginseng Radix can be a candidate for regenerating CNS injury.