• 가정간호학회지
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• 제31권1호
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• pp.16-29
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• 2024

Purpose: This scoping review aimed to synthesize the characteristics and effects of interventions designed to prevent unintentional home injuries in older adults in Korea. Methods: The review was conducted following the Joanna Briggs Institute protocol. A literature search was performed for studies published between 2001 and 2022 in the DBPia, RISS, KMBase, and NDSL databases. A total of 1,620 studies were identified, and 27 studies were included in the final analysis. Data were analyzed for characteristics of the literature, intervention-related unintentional injury mechanisms, and safety areas. Results: Most selected studies utilized a quasi-experimental design and targeted elderly women. In terms of injury mechanisms, 21 of 27 studies focused on falls, 2 on fire/disaster, 3 on drugs, and 1 on food. The most common preventive intervention for falls was exercise, and its effectiveness was verified using physical safety variables. Interventions in the fire/disaster, drug, and food domains were all educational, and changes in knowledge, behavior, and attitude were verified. Conclusion: This study confirmed the effectiveness of interventions for preventing unintentional injuries in the homes of community-dwelling older adults. These findings can serve as a foundation for developing and implementing unintentional injury prevention interventions at home for community-dwelling older adults. Multidisciplinary research is needed to address multifaceted safety issues by considering the home environment and injury risk factors.

• 한국환경보건학회지
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• 제34권1호
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• pp.62-69
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• 2008

The life cycle assessment method for environmental impact assessment was used, in this study, to assess the production process of wheat flour which is the most important material in the food industry. Environmental impact assessments were compared between that of the Ministry of Environment, Republic of Korea (method I) with that of the Ministry of Commerce, Industry and Energy (method II). Life cycle inventories (LCI) was performed using internal and external databases and the production statistics database of company S. The procedure of life cycle impact assessment (LCIA) was followed in terms of classification, characterization, normalization and weighting to identify the key issues. The impact categories of method I were divided into 8 categories with consideration of : abiotic resources depletion, global warming, ozone depletion, photochemical oxidant creation, acidification and eutrophication. The impact categories of method II were divided into 10 categories with consideration of: abiotic resources depletion, global warming, ozone depletion, photochemical oxidant creation, acidification, eutrophication, human toxicity, freshwater aquatic ecotoxicity, marine aquatic ecotoxicity and terrestrial ecotoxicity.

• Biomolecules & Therapeutics
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• 제25권5호
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• pp.482-489
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• 2017

Individual differences in drug responses are associated with genetic and epigenetic variability of pharmacogene expression. We aimed to identify the relevant miRNAs which regulate pharmacogenes associated with drug responses. The miRNA and mRNA expression profiles derived from data for normal and solid tumor tissues in The Cancer Genome Atlas (TCGA) Research Network. Predicted miRNAs targeted to pharmacogenes were identified using publicly available databases. A total of 95 pharmacogenes were selected from cholangiocarcinoma and colon adenocarcinoma, as well as kidney renal clear cell, liver hepatocellular, and lung squamous cell carcinomas. Through the integration analyses of miRNA and mRNA, 35 miRNAs were found to negatively correlate with mRNA expression levels of 16 pharmacogenes in normal bile duct, liver, colon, and lung tissues (p<0.05). Additionally, 36 miRNAs were related to differential expression of 32 pharmacogene mRNAs in those normal and tumorigenic tissues (p<0.05). These results indicate that changes in expression levels of miRNAs targeted to pharmacogenes in normal and tumor tissues may play a role in determining individual variations in drug response.

• Agribusiness and Information Management
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• 제11권1호
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• pp.1-9
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• 2019

This research intends to propose the methodology for analyzing the current trends of agriculture, which directly connects to the survival of the nation, and through this methodology, identify the agricultural trend of Korea. Based on the relationship between three types of data - policy reports, academic articles, and news articles - the research deducts the major issues stored by each data through LDA, the representative topic modeling method. By comparing and analyzing the LDA results deducted from each data source, this study intends to identify the implications regarding the current agricultural trends of Korea. This methodology can be utilized in analyzing industrial trends other than agricultural ones. To go on further, it can also be used as a basic resource for contemplation on potential areas in the future through insight on the current situation. database of the profitability of a total of 180 crop types by analyzing Rural Development Administration's survey of agricultural products income of 115 crop types, small land profitability index survey of 53 crop types, and Statistics Korea's survey of production costs of 12 crop types. Furthermore, this research presents the result and developmental process of a web-based crop introduction decision support system that provides overseas cases of new crop introduction support programs, as well as databases of outstanding business success cases of each crop type researched by agricultural institutions.

• Journal of Menopausal Medicine
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• 제23권3호
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• pp.146-155
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• 2017

Postmenopausal women aged 50s generally experience gradual changes in body such as decline in antioxidant and estrogen levels as the body ages. To overcome these aging-associated changes, the needs for health functional foods are increasing. Dendropanax morbifera (DM) have antioxidant effects, anti-inflammatory against cancer cells, antidiabetic, and antiatherogenic effect which are associated with postmenopausal symptoms. We analyzed clinical effects of DM on aging-related symptoms by reporting their antioxidant, anticancer and inflammatory activity, etc. and their bioactivity. Data sources EMBASE, SCOPUS, PubMed, Web of Science, and Google Scholar databases were searched up to August 2016 for studies investigating medicinal plants in prevention and treatment of diabetes. The search terms were "Dendropanax morbifera". The reference lists of articles were also reviewed for additional relevant studies. Extracts of DM have various efficacy such as antioxidant, anti-cancer, anti-inflammatory activity and anti-thrombotic effect.

• 대한약침학회지
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• 제22권3호
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• pp.122-130
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• 2019

Objectives: The medicinal plants are believed to enhance the natural resistance of the body to infections. Some of the main constituents of the plant and derived materials such as, proteins, lectins and polysaccharides have anti-inflammatory effects. Portulaca oleracea (P. oleracea) were used traditionally for dietary, food additive, spice and various medicinal purposes. This review article is focus on the anti-asthmatic effects of P. oleracea and its constituents. Methods: Various databases, such as the PubMed, Scopus, and Google Scholar, were searched the keywords including "Portulaca oleracea", "Quercetin", "Anti-inflammatory", "Antioxidant", "Cytokines", "Smooth muscle ", and " Relaxant effects " until the end of Jul 2018. Results: P. oleracea extracts and its constituents increased $IFN-{\gamma}$, IL-2, $IFN{\gamma}/IL-4$ and IL- 10/IL-4 ratio, but decreased secretion of $TNF-{\alpha}$, IL-4 and chemokines in both in vitro and in vivo studies. P. oleracea extracts and quercetin also signifcantly decreased production of NO, stimulated ${\beta}$-adrenoceptor and/or blocking muscarinic receptors in tracheal smooth muscles. Conclusion: P. oleracea extracts and quercetin showed relatively potent anti-asthmatic effects due to decreased production of NO, inflammatory cytokines and chemokines, reduced oxidant while enhanced antioxidant markers, and also showed potent relaxant effects on tracheal smooth muscles via stimulatory on ${\beta}$-adrenoceptor or/and blocking muscarinic receptors.

• 동아시아경상학회지
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• 제11권1호
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• pp.41-51
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• 2023

Purpose - The prior literature has shown that there is a lack of a complete assessment of the key decisions in cold chain logistics. Such a study is required to offer recommendations for research in this expanding but under-researched topic with potentially significant management ramifications. Research design, Data, and methodology - The current researcher accumulated peer-reviewed sources from databases to augment each chosen study's validity. Selection varied between seminal works and much of the existing literature. The selection process was consistent with using a content checklist that established the inclusion and exclusion criteria. Result - The research findings indicate total five solutions regarding better decision in Cold Chain Logistics (CCL), such as (1) Pricing Decision in Cold Chain Logistics, (2) Decision on Temperature Control Decision in Cold Chain Logistics, (3) Supply Chain Network Design in Cold Chain Logistics, (4) Decision on Minimizing Inventory in Cold Chain Logistics, (5) Decision on Logistics Distribution. Conclusion - Stability of a cold chain should be maintained from manufacture or via logistical components and cold logistics products are susceptible to several variables, such as temperature, and degradation can easily harm food supply, product prices, and human health. Product safety infractions substantially impact human health, among other losses linked with a functioning CCL.

• The Journal of Asian Finance, Economics and Business
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• 제9권8호
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• pp.1-6
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• 2022

This paper uses the gravity model estimated by the random effect method to analyze the factors affecting Vietnam's coffee export turnover for the period 2007-2020 major markets according to statistics from the General Statistics Office and the General Department of Customs. Coffee export turnover was collected from the General Statistics Office, General Department of Customs, and Vietnam Cacao Coffee Association. The authors calculated the price of coffee based on output and export value from data on coffee export turnover; the authors calculated the economic gap based on population and Gross Domestic Product data (reference: geographic distance metrics on the website: http://www.distancefromto.net/countries.php) and other data was collected based on the databases of the Food and Agriculture Organization of the United Nations, the International Monetary Fund, and World Bank organizations. The results of the study show that from 2007 to 2020, the factors of Vietnam's export price of coffee, geographical distance, Gross Domestic Product of the importing country and Gross Domestic Product of Vietnam, the population of Vietnam, the economic gap between Vietnam and the importing country, the openness of the economy, all have an impact on Vietnam's coffee export turnover. Finally, some conclusions about the policy's impact are made based on the empirical results of the paper.

• Journal of Ecology and Environment
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• 제46권2호
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• pp.126-135
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• 2022

Background: Pollinators are important ecological elements due to their role in the maintenance of ecosystem health, wild plant reproduction, crop production and food security. The pollinator-plant interaction supports the preservation of plant and animal populations and it also improves the yield in pollination dependent crops. Having knowledge about the plant-pollinator interaction is necessary for development of pesticide risk assessment of pollinators and conservation of endangering species. Results: Traditional methods to discover the relatedness of insects and plants are based on tracing the visiting pollinators by field observations as well as palynology. These methods are time-consuming and needs expert taxonomists to identify different groups of pollinators such as insects or identify flowering plants through palynology. With pace of technology, using molecular methods become popular in identification and classification of organisms. DNA metabarcoding, which is the combination of DNA barcoding and high throughput sequencing, can be applied as an alternative method in identification of mixed origin environmental samples such as pollen loads attached to the body of insects and has been used in DNA-based discovery of plant-pollinator relationship. Conclusions: DNA metabarcoding is practical for plant-pollinator studies, however, lack of reference sequence in online databases, taxonomic resolution, universality of primers are the most crucial limitations. Using multiple molecular markers is preferable due to the limitations of developed universal primers, which improves taxa richness and taxonomic resolution of the studied community.

• Journal of Nutrition and Health
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• 제55권4호
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• pp.430-440
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• 2022

셀레늄은 산화스트레스 방어 기능으로 인체의 면역기능 유지에 필수적 역할을 하고, 세포의 항산화기능, 면역기능, 갑상선호르몬 조절, 약물이나 중금속 위해에 대한 방어, 만성질환의 위험 감소에 필수 역할을 하는 미량무기질이다. 셀레늄 섭취의 부족은 암, 심혈관질환, 당뇨병, 신경질환, 골관절 및 근육괴사와 약화, 갑상선질환, 염증성 질환 등 다양한 만성적 질환의 위험을 높인다. 본 논문은 2020 한국인 영양소 섭취기준에서 셀레늄의 제정과 개정 근거 기준에 대해 설명하고, 셀레늄 데이터베이스의 현황과 향후 2025 한국인 영양소 섭취기준 설정을 위한 필요 연구에 대해 논의하였다. 셀레늄의 2020 한국인 영양소 섭취기준은 2015년에 이어 혈장 셀레노프로테인 P 수준이 최대가 되는 셀레늄의 평균필요량을 지표로 사용하였고, 중국인 대상의 보고치에 한국인의 기준체중과 변이계수를 적용하는 방법이 적용되었으며, 2015년에 비해 참고체중치의 변경에 따라 성별, 연령별 셀레늄 섭취기준에서 약간의 개정이 있었다. 향후 셀레늄 섭취기준 설정의 발전을 위해서는 1) 한국인 대상의 혈장 셀레노프로테인 P의 최대수준을 나타내는 셀레늄 섭취량을 파악하기 위한 셀레늄 중재연구가 필요하고, 2) 셀레늄 섭취량 판정의 정확성을 높이기 위한 영양평가 프로그램내 식품 셀레늄 데이터베이스의 검토와 식품의 셀레늄 함량 분석을 확대해야 하며, 3) 국민의 셀레늄 섭취와 체내 생물학적 지표와의 관계를 건강한 일반인뿐만 아니라 질환자 및 운동선수와 같은 특수 환경의 대상자들로 확대하는 연구가 요구된다.