• Title/Summary/Keyword: follow up

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Factors Influencing the Background Parenchymal Enhancement in Follow-Up Breast MRI after Adjuvant Endocrine Therapy

  • Youk, Ji Hyun;Son, Eun Ju;Kim, Jeong-Ah
    • Investigative Magnetic Resonance Imaging
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    • v.19 no.2
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    • pp.99-106
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    • 2015
  • Purpose: To investigate factors influencing the evaluation of background parenchymal enhancement (BPE) at follow-up breast magnetic resonance imaging (MRI) after adjuvant endocrine therapy. Materials and Methods: One hundred twelve women with breast cancer and MRI of the contralateral unaffected breast before and after endocrine therapy were identified. Two readers in consensus performed blinded side-by-side comparison of BPE (minimal, mild, moderate, and marked) before and after therapy with categorical scales. Age, body mass index, menopausal status, treatment regimen (selective estrogen receptor modulator or aromatase inhibitor), chemotherapy, follow-up duration, BPE at baseline MRI, MRI field strength before and after therapy, and recurrence were analyzed for their influences on decreased BPE. Results: Younger age, premenopausal status, treatment with selective estrogen receptor modulator, MRI field strength, and moderate or marked baseline BPE were significantly associated with decreased BPE. In multivariate analysis, MRI field strength and baseline BPE showed a significant association. Conclusion: MRI field strength and baseline BPE before and after therapy .were associated with decreased BPE at post-therapy, follow-up MRI.

Perceived Working Conditions and Sickness Absence - A Four-year Follow-up in the Food Industry

  • Siukola, Anna E.;Virtanen, Pekka J.;Luukkaala, Tiina H.;Nygard, Clas-Hakan
    • Safety and Health at Work
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    • v.2 no.4
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    • pp.313-320
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    • 2011
  • Objectives: To analyze the association between changes in perceived physical and psychosocial working conditions and change of sickness absence days in younger and older (< 50 and ${\geq}50$ years) food industry employees. Methods: This was a follow up study of 679 employees, who completed working conditions survey questionnaires in 2005 and 2009 and for whom the requisite sickness absence data were available for the years 2004 and 2008. Results: Sickness absence increased and working conditions improved during follow-up. However, the change of increased sickness absence days were associated with the change of increased poor working postures and the change of deteriorated team spirit and reactivity (especially among < 50 years). No other changes in working conditions were associated with the changes in sickness absence. Conclusion: Sickness absence is affected by many factors other than working conditions. Nevertheless, according to this study improving team spirit and reactivity and preventing poor working postures are important in decreasing sickness absence.

Quantification of Immunoglobulin G against Trypanosoma cruzi in Individuals with Chronic Chagas Disease Treated with Nifurtimox and Evaluated in Prolonged Follow-Up

  • Munoz, Gabriela;Vergara, Camilo;Martinez, Gabriela;Apt, Werner;Zulantay, Ines
    • Parasites, Hosts and Diseases
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    • v.57 no.1
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    • pp.39-41
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    • 2019
  • In the indeterminate chronic period of Chagas disease (ChD) the treatment has not been conclusive, because the serological negativization requires many years. This study aims to evaluate the efficacy of nifurtimox (NF) in the treatment of chronic ChD in prolonged follow-up by serological techniques of indirect immunofluorescence assay (IFA) and enzyme-linked immunosorbent assay (ELISA) IgG comparing 2 groups of patients, treated and non treated. Mann-Whitney test was performed for ELISA and IFA, with significant difference between the groups (P<0.05). IgG levels were lower in individuals treated compared with untreated patients, indicating chemotherapeutic efficacy in prolonged follow-up.

The Influence of Public Welfare and Audit Findings on Audit Opinion: Empirical Evidence from Provincial Data in Indonesia

  • YAYA, Rizal;IRFANA, Siti Syifa;RIYADH, Hosam Alden;SOFYANI, Hafiez
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.4
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    • pp.181-191
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    • 2021
  • The aim of the study is to empirically investigate and analyze the influence of public welfare, audit findings, and follow-up of audit recommendations on audit opinion with the disclosure level of financial reports as an intervening variable using agency theory and signaling theory. To achieve this purpose, a quantitative research method was employed. Population of this study is Provincial Government Financial Reports in Indonesia for fiscal years 2016 to 2018. There were 84 financial reports that met the criteria of purposive sampling. The data were gathered from the websites of the Audit Board of the Republic of Indonesia and the Indonesian Central Bureau of Statistics. In this study, the hypothesis-testing tool is path analysis using the Statistical Package for Social Sciences version 15. Based on the multiple regression analysis, the results show that audit findings, public income, and the disclosure level of financial reports significantly influenced audit opinion. Besides, the follow-up of audit recommendations and public health significantly influenced audit opinion through the disclosure level of financial reports. This study suggests that, in order to have better audit opinion, local governments need to improve public welfare, follow-up audit finding, and disclose more details in financial report.

A Study on Sequential Design of Experiments Using Non-Central Composite Designs (비중심합성계획을 이용한 순차적 실험방법에 관한 연구)

  • Shin, Byung-Cheol;Byun, Jai-Hyun;Yun, Tae Hong
    • Journal of Korean Society for Quality Management
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    • v.49 no.1
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    • pp.31-45
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    • 2021
  • Purpose: A noncentral composite design method is to be developed to explore farther region for the first factorial design. A general guideline for sequential experimentation is provided. Methods: (1) A non-overlapping noncentral composite design (NNCD) is developed, in which the second factorial design shares one design point that indicates the best response value in the first factorial design. (2) Four composite designs are compared in terms of the four design evaluation criteria, which are D-, A, G, and I-optimality. (3) A follow-up design strategy is suggested based on the interaction effect, direction of improvement, number of factors. Results: (1) NNCD and model building method are presented, which is useful for exploring farther region from first factorial design block. (2) The performances of the four composite designs are compared. (3) A follow-up design strategy is suggested. Conclusion: (1) NNCD will be useful to explore farther region for the first factorial design. (2) A follow-up design strategy can be beneficial to the experimental practitioners for product and process design and improvement.

Long-Term Outcomes of Placement of a Single Transverse Stent through the Anterior Communicating Artery via the Nondominant A1 in Coil Embolization of Wide-Necked Anterior Communicating Artery Aneurysms

  • Ban, Seung Pil;Kwon, O-Ki;Kim, Young Deok
    • Journal of Korean Neurosurgical Society
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    • v.65 no.1
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    • pp.40-48
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    • 2022
  • Objective : Placement of a single transverse stent via the nondominant A1 across the anterior communicating artery (AComA) into the contralateral A2 can provide sufficient neck coverage for wide-necked bifurcation AComA aneurysms. The authors described the feasibility, safety and long-term outcomes of this technique. Methods : Between January 2015 and February 2018, placement of a single transverse stent via the nondominant A1 was attempted in 17 wide-necked bifurcation AComA aneurysms. The authors reviewed the medical records and radiological studies. Results : The technical success rate was 94.1% (16/17). Periprocedural thromboembolic complications occurred in one patient (6.3%) without permanent neurological deficits. The mean clinical follow-up duration was 39.9±9.8 months. No deaths or delayed thromboembolic complications occurred. The mean angiographic follow-up duration was 38.9±9.8 months. The immediate and final follow-up complete occlusion rates were 87.4 and 93.7%, respectively. There was no recanalization during the follow-up period. Conclusion : Placement of a single transverse stent via the nondominant A1 across the AComA into the contralateral A2 is a feasible and relatively safe endovascular technique for the treatment of wide-necked bifurcation AComA aneurysms, with good long-term occlusion rates and a reasonable complication rate, if only the nondominant A1 is applicable.

The clinical success of ART restorations and Hall technique in primary molars: a randomized 18-month follow-up study

  • Esra Oz;Zuhal Kirzioglu;Canan Kale
    • Restorative Dentistry and Endodontics
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    • v.48 no.2
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    • pp.19.1-19.12
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    • 2023
  • Objectives: The aim of the study was to evaluate the clinical and radiographic success of the Hall technique (HT) and atraumatic restorative treatment (ART) restorations using high-viscosity glass-ionomer cement for the management of occlusal carious lesions in primary molars. Materials and Methods: This randomized clinical study observed 40 children (aged 5-6 years). For each child, one tooth was treated with HT and one with ART. The primary outcome measures for HT restorations were successful, minor, and major failure rates. Clinical evaluations of ART restorations were performed according to the modified United States Public Health Service criteria during 18-month follow-up. McNemar test was used for statistical analysis. Results: Thirty of 40 (75%) participants returned for 18 months of follow-up. In the clinical evaluations of teeth that were treated with HT, the patients did not have complaints of pain or other symptoms, all crowns remained in the oral cavity, the gums were healthy, and the teeth were functional in all evaluations. At the end of the 18-month follow-up, the surface texture and marginal integrity criteria of ART restorations were recorded as 26.7% and 33.3%, respectively. In the radiographic evaluation of 30 patients treated with ART and HT, all restorations were considered successful. Conclusions: The 18-month clinical and radiographic results after treatments applied to single-surface cavities in anxious children showed that both treatment methods were successful.

Hormonal Changes in Women Undergoing Bariatric Surgery: A Comparative Study with a Control Group

  • Taha Anbara
    • Development and Reproduction
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    • v.27 no.3
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    • pp.117-126
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    • 2023
  • Bariatric surgery is an effective treatment option for obesity, but its effects on reproductive hormones are not well understood. This study aimed to investigate the impact of bariatric surgery on estrogen and progesterone levels in women with obesity. This was a prospective study that included 87 women with obesity who underwent bariatric surgery and 87 control women with obesity who did not. Blood samples were collected at baseline and at 3-month and 6-month follow-up periods to measure reproductive hormones and Adiponectin as well as medical history and physical examination for endometriosis and polycystic ovary syndrome (PCOS). The study found that sleeve gastrectomy significantly increased follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels in the bariatric surgery group compared to the control group at 3 and 6-month follow-up. There was no significant difference in the mean levels of estrogen and progesterone between the two groups at the 3-month follow-up period. Bariatric surgery leads to significant weight loss in women with obesity, but it does not seem to have a significant impact on estrogen and progesterone levels in the short-term. Future studies with longer follow-up periods are needed to investigate the long-term effects of bariatric surgery on reproductive hormones.

Correlation Analysis between Kinematic Variables and Ground Slope Perception Ability during Golf Putting (골프 퍼팅 시 운동학적 변인과 경사도 인지능력 간 상관성 분석)

  • Lee, Jae-Woo;Im, Young-Tae;Kwon, Moon-Seok;Park, Jun-Sung
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.3
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    • pp.727-734
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    • 2021
  • The purpose of this study was to analyze correlation between kinematic variables and ground slope perception ability during golf putting. 16 collegiate golfers were participated. To collect and analyze the kinematic data of putter head, SAMPutt lab was used(70 Hz). It was performed Pearson's correlation analysis using SPSS. The level of significance was at .05. As a results, right was correlated with backswing in flat. Toe-up was correlated with follow-through and left was correlated with aim, backswing, impact, follow-through, and loft in slice 1°. Toe-down was correlated with aim, backswing, impact in slice 2°. Toe-up was correlated with follow-through in hook 2°. In conclusion, it is important to improve the putting stroke through repetitive ground slope perception training.

The Treatment for Hallux Valgus with Scarf Osteotomy in Elderly Patients with Osteoporosis (골다공증이 있는 고령의 환자에서 Scarf 중족골 절골술을 이용한 무지 외반증의 치료)

  • Hwang, Seung Hyun;Lee, Su Chan;Nam, Chang Hyun;Baek, Ji-Hoon;Ahn, Hye Sun
    • Journal of Korean Foot and Ankle Society
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    • v.21 no.3
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    • pp.93-97
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    • 2017
  • Purpose: The aim of this study was to evaluate the radiological and clinical outcomes of scarf osteotomy for hallux valgus (HV) deformity in elderly patient with osteoporosis. Materials and Methods: A total of 58 elderly patients (mean age, 72.6 years) underwent scarf osteotomy for HV deformity between 2008 and 2015. The mean follow-up period was 24.4 months. Of the 58 patients, 42 were diagnosed with osteoporosis and 16 were diagnosed as normal. The radiological and clinical outcomes were assessed preoperatively, postoperatively, and at final follow-up, including HV angle, intermetatarsal (IM) angle, American Orthopaedic Foot and Ankle Society (AOFAS) score, patient satisfaction, visual analogue scale (VAS), and complication. Results: There was no significant difference in HV angle and IM angle between the osteoporosis group and normal bone mineral densitometry group at all time points, preoperative, postoperative, and final follow-up. Moreover, there was no statistically significant difference between the two groups with respect to the AOFAS score and VAS evaluations. In the osteoporosis group, the mean HV angle improved from $36.7^{\circ}$ preoperatively to $11.3^{\circ}$ at the time of final follow-up, and the mean IM angle improved from $13.2^{\circ}$ to $5.7^{\circ}$. The mean AOFAS score improved from 52.6 preoperatively to 89.1 at the time of final follow-up. With respect to satisfaction, 83.4% of patients were very satisfied or satisfied. There were no serious complications, and all cases showed complete union at the osteotomy site. Conclusion: We believed that scarf osteotomy is a safe, effective procedure for the correction of elderly patients with osteoporosis.