• The Korean Journal of Zoology
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• v.33 no.4
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• pp.428-434
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• 1990

Uptake and accumulation of vitellogenin into ovary were traced by radiolabeled vitellogenin produced in the fat body. Vitellogenin reached the oocytes through the follicle cells and the intercellular space and penetrated the oocyte membrane via the endocytotic vesicles and then accumulated to the growing yolk granules.

• Reproductive and Developmental Biology
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• v.28 no.3
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• pp.147-153
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• 2004

The oocyte and its surrounding granulosa cells co-exist in a closed compartment called a follicle, although they receive many signals from other parts of the body. It is well established that the intercellular communications between the oocyte and granulosa cells are required for normal oocyte development and ovulation during folliculogenesis. Gap junctions are intercellular channels allowing the direct transmission of ions and small molecules between coupled cells. Several lines of studies have shown that multiple connexins (Cx, subunits of gap junction) are expressed in mammalian ovarian follicles. Among them, two major connexins Cx37 and Cx43 are expressed in different manner. While the gap junction channels formed by Cx37 are localized between the oocyte and encompassing granulosa cells, the intercellular channels by Cx43 are located between granulosa cells. In this review, I will summarize the general properties of gap junction channels and discuss their possible formation (or compatibility) of intercellular channels formed by the oocyte and granulosa cells.

• The Journal of Korea Robotics Society
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• v.4 no.1
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• pp.34-42
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• 2009

Rodents, specially rats, can recognize distance and shape of an object and also pattern of the textures by using their whiskers. Mechanoreceptors surrounding the root of whisker in their follicle measure deflection of the whisker. Rats can move their whisker back and forth freely. This ability, called active whisking or active sensing, is one of characteristics of rat behaviours. Many researches based on the mechanism have been progressed. In this paper, we test a simple and accurate method based on deflection of the whisker: we designed biomimetic whiskers modeling after a structure of follicle using the microphone. The microphone sensor measures a mechanical vibration. Attaching an artificial whisker beam to the microphone membrane, we can detect a vibration of whisker and this can show the deflection amount of whisker indirectly.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.4
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• pp.132-137
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• 2012

Empty follicle syndrome (EFS) is a condition in which no oocytes are retrieved after an apparently adequate ovarian response to stimulation and meticulous follicular aspiration. EFS can be classified into 'genuine' and 'false' types according to hCG levels. It is a rare condition of obscure etiology. The existence of genuine EFS has been questioned and is still controversial. The limitation around EFS is that the definition of EFS is obscure. Management of patients with EFS is a challenge to physicians. No single treatment is known to be universally effective. However, patients should be adequately informed regarding the importance of correct hCG administration because improper hCG administration is a common and preventable cause of EFS. EFS is a syndrome that deserves additional study because such investigation could lead to a further understanding of ovarian biology and infertility.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.1
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• pp.10-14
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• 2012

The ovarian follicles develop initially from primordial follicles. The majority of ovarian primordial follicles are maintained quiescently as a reserve for the reproductive life span. Only a few of them are activated and develop to an advanced follicular stage. The maintenance of dormancy and activation of primordial follicles are controlled by coordinated actions of a suppressor/activator with close communications with somatic cells and intra-oocyte signaling pathways. Many growth factors and signaling pathways have been identified and the transforming growth factor-beta superfamily plays important roles in early folliculogenesis. However, the mechanism of maintaining the dormancy and survival of primordial follicles has remained unknown for decades. Recently, since the first finding that all primordial follicles are activated prematurely in mice deficient forkhead box O3a, phosphatidylinositol 3 kinase/phosphatase and tensin homolog (PTEN) signaling pathway was reported to be important in the regulation of dormancy and initial follicular activation. With these informations on early folliculogenesis, clinical application can be expected such as in vitro maturation of immature oocytes or in vitro activation of follicles by PTEN inhibitor in cryopreserved ovarian cortical tissues for fertility preservation.

• IMMUNE NETWORK
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• v.14 no.5
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• pp.227-236
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• 2014

Understanding germinal center reactions is crucial not only for the design of effective vaccines against infectious agents and malignant cells but also for the development of therapeutic intervention for the treatment of antibody-mediated immune disorders. Recent advances in this field have revealed specialized subsets of T cells necessary for the control of B cell responses in the follicle. These cells include follicular regulatory T cells and Qa-1-restricted cluster of differentiation $(CD)8^+$ regulatory T cells. In this review, we discuss the current knowledge related to the role of regulatory T cells in the B cell follicle.

• Journal of Embryo Transfer
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• v.2 no.1
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• pp.33-35
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• 1987

This study was carried out to investigate the seasonal effect on the recovery rate of embryos in donors and on the conception rate in recipients following embryo transfer. The results obtained from this experiment were summarized as follows: 1. The ovulation point in winter and summer was 28.6 and 28.6, respectively. There was no difference in ovulation point between two seasons. More embryos recovered in the winter (27,0) than the summer (20.9). 2. The number of CL, unruptured follicle, hemorrhagic follicle, young born and pregnancy rate in the winter were 6.0,4.8,1.5,1.8 and 75%, and those in the summer were 2.9,5.7, 3.8, 2.2 and 46.7%, respectively. The rate of synchronization of recipients in the winter showed better results than that in the summer.

• Imaging Science in Dentistry
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• v.43 no.4
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• pp.303-308
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• 2013

This report describes a 31-year-old female patient with six impacted teeth. The crowns of the impacted teeth were surrounded with cyst-like lesions with a mixed internal structure and well-defined cortical borders. Microscopic examination of the specimen obtained from the follicle of the left mandibular third molar tooth revealed loose to moderately dense collagenous connective tissue with abundant calcified material and sparse epithelial islands. A diagnosis of multiple calcifying hyperplastic dental follicles was made.

• Journal of Ginseng Research
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• v.20 no.2
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• pp.149-153
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• 1996

Studies were Performed to determine whether the water fraction of Panax ginseng Protected radiation damage to hair medullar cells of N:GP(s) mice after in vivo irradiation with $^{60}Co{\;}{\gamma}-rays$. The hair follicles in the middle of the growth cycle were analysed 3 days after 3 Gy irradiation for the changes in the number of cells in the forming medulla of the hair in the region just above the germinal matrix of the growing (anagen) hair follicle. The radioprotective effect of ginseng was compared with the irradiation control. The medullar cell count per unit length ($100{\;}\mu\textrm{m}$) of hair follicle was higher in the pretreated-groups of ginseng, both oral (2 mg/ml of drinking water, p<0.05) and intraperitoneal (0.3 mg/head, p<0.001) treatments, than the irradiation control. These data suggested that the water fraction of Panax ginseng may reduce cell damages on the body surface caused by ${\gamma}-rays$.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.1
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• pp.116-126
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• 2016

Objectives: The purpose of these cases is to report the effects of oriental medicine on two patients with premature ovarian failure. Methods: Two patients who had amenorrhea and hot flashes caused by premature ovarian failure were treated by oriental medicine such as herb medication. We estimated the effects of treatments by follow-up measurements of serum hormone level, menstrual cycle and symptoms. Besides, follicle and endometrium were checked by ultrasonography for academic research.Results After treatments, their symptoms of premature ovarian failure were improved and the menstrual cycle resumed. And the level of serum Follicle Stimulating Hormone decreased and the level of serum E₂ increased.Conclusions Two cases shows that oriental medicine has effects on patients with premature ovarian failure by follow-up measurements of serum hormone level, menstrual cycle and symptoms.