• Journal of the Korean Society for Nondestructive Testing
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• v.28 no.6
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• pp.531-537
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• 2008

One of the fundamental features of time reversal acoustic (TRA) techniques is the ability to focus the propagating ultrasonic beam to a specific point within the test material. Therefore, it is important to understand the focusing properties of a TR device in many applications including nondestructive testing. In this paper, we employ an analytical scheme for the analysis of TR beam focusing in a homogeneous medium. More specifically, a nonparaxial multi-Gaussian beam (NMGB) model is used to simulate the focusing behavior of array transducers composed of multiple rectangular elements. The NMGB model is found to generate accurate beam fields beyond the nonparaxial region. Two different simulation cases are considered here for the focal points specified on and off from the central axis of the array transducer. The simulation results show that the focal spot size increases with increasing focal length and focal angle. Furthermore, the maximum velocity amplitude does not always coincide with the specified focal point. Simulation results for the off-axis focusing cases do demonstrate the accurate steering capability of the TR focusing.

• Korean Journal of Optics and Photonics
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• v.4 no.4
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• pp.428-433
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• 1993

The second harmonic of Q-switched Nd:YAG laser beam with gaussian mode is cut off by pinhole of a certain radius and its central portion passed through pinhole is focused by converging lens. It is confirmed that the shape of this beam in focal region is central symmetric but non-gaussian. Change of transmittance due to self-focusing is investigated by scanning (z-scan) $CS_2$ of 1 mm thickness in the focal region. It is found that the observed results can be consistently explained by Fresnel theory within 1.5% accuracy and efficiency of self-focusing depends on spatial shape of incident beam.

• Korean Journal of Veterinary Research
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• v.54 no.1
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• pp.59-62
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• 2014

A 12-year-old, castrated male Yorkshire terrier dog presented with frequent regurgitations that had begun 45 days earlier and become more progressive. Radiographs revealed an air-trap region behind the cranial esophageal sphincter muscle in the esophagus and esophagographies with barium contrast showed mild esophageal dilation with decreased motility. Esophageal motility increased within 5 min of neostigmine methylsulfate administration and acetylcholine receptor antibodies titer increased to beyond the normal range. Based on these findings, acquired myasthenia gravis with focal form was diagnosed, making this the first such case diagnosed by an acetylcholine receptor antibody test in Korea.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• fall
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• pp.144-145
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• 2021

Variable range of focal length of Moiré lens is designed to change the phase pattern, which is varifocal lens system using two thin layers with Moiré pattern and suitable to applied to AR/VR system because of the relatively simple structure, large aperture size, and wide variable range. We analyze the change of focal length region according to the phase pattern and verify the design to make the prototype patterns using DOE.

• The Journal of Korean Medicine
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• v.26 no.3 s.63
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• pp.146-161
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• 2005

Objectives : This study investigated neuroprotective effects of Polygoni Multiflori Radix on cerebral ischemia of hyperlipidemic rats. Methods : Effects of Polygoni Multiflori Radix were evaluated with changes of infarct size after He focal cerebral ischemia induced by the middle cerebral artery occlusion, changes of pyramidal neurons and expressions of Bax and Bcl-2 apoptosis regulating factors after global cerebral ischemia, and changes of serum lipid revels after cerebral ischemia. Results & Conclusions : Results obtained were as follows; 1. Polygoni Multiflori Radix did net reduce the focal cerebral infarct size induced by the middle cerebral artery occlusion under both hyperlipidemic and normal-lipid conditions. 2. Polygoni Multiflori Radix significantly reduced the increase of neuronal cell death in CAl region of hippocampus induced by the global cerebral ischemia under both hyperlipidemic and normal-lipid conditions. 3. Polygoni Multiflori Radix significantly reduced the increase of Bax expression in the CAl region of the hippocampus induced by global cerebral ischemia under both hyperlipidemic and normal-lipid conditions. 4. Polygoni Multiflori Radix significantly increased Bc1-2 expression in the CA1 region of the hippocampus after global cerebral ischemia under normal-lipid condition, but was not effective on that under hyperlipidemic condition. 5. Polygoni Multiflori Radix was not effective on serum total-cholesterol, HDL-cholesterol, LDL-cholesterol and triglyceride levels under normal-lipid conditions, irrespective of focal cerebral infarct or global cerebral ischemia. 6. Polygoni Multiflori Radix significantly reduced the increase of serum total-cholesterol and triglyceride levels, and increased serum LDL-cholesterol level under hyperlipidemic conditions, irrespective of foc31 cerebral infarct or global cerebral ischemia.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.66.2-66.2
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• 2016

KASI and NAOJ are making collaborating efforts to implement faster mapping capability into the new 275-500 GHz Atacama Submillimeter Telescope Experiment focal plane array (FPA). Feed horn antenna is one of critical parts of the FPA. Required fractional bandwidth is almost 60 % while that of traditional conical horn is less than 50 %. Therefore, to achieve this wideband performance, we adopted a horn of which the corrugation depths have a longitudinal profile. A profiled horn has features not only of wide bandwidth but also of shorter length compared to a linear-tapered corrugated horn, and lower cost fabrication with less error can be feasible. In our design process the flare region is represented by a cubic splined curve with several parameters. Parameters of the flare region and each dimension of the throat region are optimized by a differential evolution algorithm to keep >20 dB return loss and >30 dB maximum cross-polarization level over the operation bandwidth. To evaluate RF performance of the horn generated by the optimizer, we used a commercial mode matching software, WASP-NET. Also, Gaussian beam (GB) masks to far fields were applied to give better GB behavior over frequencies. The optimized design shows >23 dB return loss and >33 dB maximum cross-polarization level over the whole band. Gaussicity of the horn is over 96.6 %. The length of the horn is 12.5 mm which is just 57 % of the ALMA band 8 feed horn (21.96 mm).

• Geophysics and Geophysical Exploration
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• v.13 no.3
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• pp.198-202
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• 2010

In and around the Korean Peninsula, 18 intraplate earthquake focal mechanisms since 1936 were analyzed to understand the characteristic of focal mechanism and regional stress orientation and tectonics. These earthquakes are largest ones from the last century and may represent the characteristics of earthquake in this region. Focal mechanism of these earthquakes show predominant strike-slip faulting with small amount of thrust components. The average P-axis is almost horizontal ENE-WSW direction. This mechanism pattern and the direction of maximum stress axis is very similar with northeastern part of China and southwestern part of Japan. However they are quite different with the eastern part of East Sea. This indicate that not only the subducting Pacific Plate from east but also the indenting Indian Plate controls focal mechanism in the far east of the Eurasian Plate.

• Journal of Acupuncture Research
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• v.25 no.1
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• pp.1-14
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• 2008

Objectives : Delayed neuronal death(DND) of pyramidal neuronsin the CA1 regions of the hippocampus has been extensively studied following global brain ischemia, whereas little is known about DND in this highly vulnerable brain region after focal brain ischemia. The aim of the present study was to investigate the effect of Gastrodiae Elata(GA) pharmacopuncture on hippocampal neuronal apoptosis in rats with focal brain ischemic injury. Materials and methods : The neuroprotective effects of water extracts of GA were investigated in middle cerebral artery occlusion(MCAo) of Sprague-Dawley(SD) rats. Seventy-five healthy SD ratswere randomly divided into five groups following MCAo : control group with focal ischemia, saline injection group, pharmacopuncture group GA-1($0.0007mg/m{\ell}/g$), pharmacopuncture group GA-2($0.00035mg/m{\ell}/g$), pharmacopuncture group GA-3($0.00014mg/m{\ell}/g$). Results : The intensity of mGluR5 increased in the GA-1 group. The intensity of Bax and the Bax/Bcl-2 ratio decreased in the GA-1 group. The intensity of Bcl-2 increased in all the GA groups. The density of neurons stained by Cresyl violet and ChAT increased in the GA-1 group. Conclusions : Our study suggests that GA pharmacopuncture at $GB_{20}$ showed anti-apoptotic and neuroprotective effects on cholinergic neuronsin focal cerebral ischemia caused by stroke in SD rats.

• The Journal of Korean Medicine
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• v.30 no.2
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• pp.1-16
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• 2009

Objectives: This study investigated the effect of Yukmijihwangtang on cerebral ischemia-induced learning and memory impairment by middle cerebral artery (MCA) occlusion in rats. Methods: The ability of learning and memory of rats was measured using the eight-arm radial maze and the passive avoidance test, and profile of cholinergic neuron was assessed in the medial septum and hippocampus region by immuno-histochemistry. Results: 1. No differences were found between groups in the number of correct choices in acquisition performance during the eight-arm radial maze task. 2. No differences were found between groups on day 1 in the error rate in acquisition performance, which is defined as the number of enters into the same arm more than once within five minutes. After 5 to 6 days of test, the number of errors was significantly reduced in the Yukmijihwangtang group (forebrain ischemia group with Yukmijihwangtang treatment), compared with the ischemia group. 3. The memory processes significantly improved in the Yukmijihwangtang group according to results of the passive avoidance test. 4. The appearance of AchE (acetylcholinesterase) in the CA1 region of hippocampus significantly decreased in the ischemia group, compared with the sham group (untreated group). The appearance of AchE in the same region significantly increased in the Yukmijihwangtang group, compared with the ischemia group. 5. The appearance of ChAT (choline acetyltransferase) in the CA1 region of the hippocampus and medial septum decreased in the ischemia group, compared with the sham group. The appearance of ChAT in the same region significantly increased in the Yukmijihwangtang group, compared with the ischemia group Conclusions: This study provides evidence that Yukmijihwangtang is effective for reviving the ability of learning and memory and damaged neurons in rats with experimental cerebral ischemia.

• Journal of Urban Science
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• v.6 no.2
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• pp.1-13
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• 2017

The air quality management in regional viewpoint was investigated for the improvement of national air pollution with various standard air pollutants. The focal region in this research is north-eastern region in asia where the many developing industries are located in neighboring countries. The major concerns were the trends of air quality in recent years and the state of environmental technologies and policies of air quality in each countries. The regional air quality management for the improvement of air pollution and the effective programs were suggested for the effective air quality management.