• Journal of Applied Biological Chemistry
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• v.64 no.2
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• pp.113-119
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• 2021

Olive (Olea europaea L.) leaves, a raw material for health functional foods and cosmetics have abundant polyphenols including oleuropein (major bioactive compound) with various biological activities: antioxidant, antibacterial, antiviral, anticancer activity, and inhibit platelet activation. Oleuropein has been reported as skin protectant, antioxidant, anti-ageing, anti-cancer, anti-inflammation, anti-atherogenic, anti-viral, and anti-microbial activity. Despite oleuropein is the important compound in olive leaves, there is still no quantitative approach to reveal oleuropein content in commercial products. Therefore, a validated method of analysis has to develop for oleuropein. In this study, the components and oleuropein content in 10 types of products were analyzed using a developed method with ultra-performance liquid chromatography to quadrupole time-of-flight mass spectrometry, charge of aerosol detector, and photodiode array. The total of 18 compounds including iridoids (1, 3, 4, 14, and 16-18), coumarin (2), phenylethanoids (5, 9, and 11), flavonoids (6-8, 10, 12, and 13), lignan (15), were tentatively identified in the leaves extract based high resolution mass spectrometry data, and the content of oleuropein in each product was almost identical between two detection methods. The oleuropein in three commercial product (A, G, H) was contained more over the suggested content, and it of five products (B, E, H, I, J) were analyzed within 5-10% error range. However, the two products (C, D) were found far lower than suggested contents. This study provides that analytical results of oleuropein could be a potential information for the quality control of leaf extract for a manufactured functional food.

• Annals of Clinical Neurophysiology
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• v.10 no.2
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• pp.104-108
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• 2008

Background: The compression of 7th cranial nerve by arteries is one of the various causes of hemifacial spasm (HFS). A few previous studies were revealed the relation between the compression of 7th cranial nerve and common trunk anomaly. We evaluated the common trunk anomalies in patients with HFS using MRI and MRA. Methods: From January 2001 to December 2005, 41 consecutive patients (9 men, mean age $54.5{\pm}12.6$) with HFS underwent MRI and MRA. T2 axial images and time-of-flight angiographies were reviewed for identification of the compression at root exit zone by two neuroradiologists and one neurologist. Results: Thirty-seven patients showed neurovascular compression on the lesion side. Twenty patients of them were shown the compression of 7th cranial nerve by anterior inferior cerebellar artery (AICA), and seventeen patients of them were shown the compression by posterior inferior cerebellar artery (PICA). Twenty-four patients of the thirty-seven patients had common trunk anomaly. In control, twelve of twenty-one subjects had common trunk anomaly, that the frequencies of common trunk anomaly of two groups were 58.8% in HFS and 57.1% in controls. In the twenty-four patients with common trunk anomaly, eighteen patients had dominant-AICA, and six patients had dominant-PICA. The rate of nerve compression by common trunk anomaly in the HFS with unilateral common trunk, dominant-AICA was 76.5% and dominant-PICA was 100%. Conclusions: This study also revealed that AICA was most common compressive artery. There was no difference between the HFS groups and control groups in frequency of common trunk anomaly. Thus, we could not demonstrate the relationship between common trunk anomaly and HFS.

• Journal of Astronomy and Space Sciences
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• v.26 no.3
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• pp.403-416
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• 2009

COMS (Communication, Ocean and Meteorological Satellite) is a geostationary satellite and developed by KARl for communication, ocean and meteorological observations. It will be tested under vacuum and very low temperature conditions in order to verify thermal design of COMS. The test will be performed by using KARI large thermal vacuum chamber, which was developed by KARI, and the COMS will be the first flight satellite tested in this chamber. The purposes of thermal balance test are to correlate analytical model used for design evaluation and predicting temperatures, and to verify and adjust thermal control concept. KARI has plan to use heating plates to simulate space hot condition especially for radiator panels of satellite such as north and south panels. They will be controlled from 90 K to 273 K by circulating GN2 and LN2 alternatively according to the test phases, while the main shroud of the vacuum chamber will be under constant temperature, 90 K, during all thermal balance test. This paper presents thermal modelling including test chamber, heating plates and the satellite without solar array wing and Ka-band reflectors and discusses temperature prediction during thermal balance test.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.3
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• pp.232-242
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• 2015

For stealth performance consideration, many UAV designs are adopting tailless lambda-shaped configurations which are likely to have unsteady dynamic characteristics. In order to control such UAVs through automatic flight control system, more accurate estimation of dynamic stability derivatives becomes essential. In this paper, dynamic stability derivatives of a tailless lambda-shaped UAV are estimated through numerically simulated forced oscillation method incorporating dynamic mesh technique. First, the methodology is validated by benchmarking the CFD results against previously published experimental results of the Standard Dynamics Model(SDM). The dependency of initial angle of attack, oscillation frequency and oscillation magnitude on the dynamic stability derivatives of a tailless UAV configuration is then studied. The results show reasonable agreements with experimental reference data and prove the validity and efficiency of the concept of using CFD to estimate the dynamic derivatives.

• KEPCO Journal on Electric Power and Energy
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• v.5 no.3
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• pp.149-156
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• 2019

In the field of maintenance of power transmission lines, drones have been used for their patrol and inspection by KEPCO since 2017. This drone technology was originally developed by KEPCO Research Institute, and now workers from four regional offices of KEPCO have directly applied this technology to the drone patrol and inspection tasks. In the drone inspection system, a drone with an optical zooming camera and a thermal camera can fly automatically along the transmission lines by the ground control system developed by KEPCO Research Institute, but its camera gimbal has been remotely controlled by a field worker. Especially the drone patrol and inspection has been mainly applied for the transmission lines in the inaccessible areas such as regions with river-crossings, sea-crossings and mountains. There are often communication disruptions between the drone and its remote controller in such extreme fields of mountain areas with many barriers. This problem may cause the camera gimbal be out of control, even though the inspection drone flies along the flight path well. In addition, interference with the reception of real-time transmitted videos makes the field worker unable to operate it. To solve these problems, we have developed the auto-tracking camera gimbal system with deep learning method. The camera gimbal can track the transmission line automatically, even when the transmitted video on a remote controller is intermittently unavailable. To show the effectiveness of our camera gimbal system, its field test results will be presented in this paper.

• Journal of Aerospace System Engineering
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• v.16 no.3
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• pp.84-92
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• 2022

The electro-hydrostatic actuator (EHA) recently has been used in flight control fields for aircraft because of its benefits of minimizing oil leakage and weight, improving safety, and etc. while independently operating the hydraulic power source and eliminating complex hydraulic piping. The aircraft of which EHA is installed inside, has the thermal management issue of EHA, because of its limited cooling source as compared with the aircraft which installs the traditional central hydraulic system. So, the thermal analysis model which predicts the thermal characteristics of EHA, is required to resolve this thermal management issue. In this study, an oil circulation circuit inside the hydraulic power module comprised of hydraulic pump and electrical motor for EHA was applied. This is for the purpose of developing the internal rotary group of hydraulic power module, which operates under the conditions of high rotation speed and hydraulic pressure. After formulating an appropriate thermal analysis model, the thermal analysis results with oil cooled or no oil cooled hydraulic control module were compared and reviewed, for the purpose of predicting the thermal characteristics of EHA.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.697-702
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• 2023

Recently, with the introduction of drones, a core technology of the 4th industrial revolution, various convergence education using drones is being conducted in school education sites. In particular, drone theory and practice education is being conducted in connection with free semester classes and career exploration. The drone convergence education program has higher learner satisfaction than simple demonstration and practice education, and the learning effect is high due to direct practical experience. However, since practical education is being conducted for a large number of learners, it is impossible to restrict and control the flight of a large number of drones in a limited place. In this paper, we propose a monitoring system that allows the instructor to monitor multiple drones in real time and learners to recognize collisions between drones in advance when multiple drones are operated, focusing on education operated in schools. The communication module used in the experiment was equipped with GPS in Murata LoRa, and the server and client were configured to enable monitoring based on the location data received in real time. The performance of the proposed system was evaluated in an open space, and it was confirmed that the communication signal was good up to a distance of about 120m. In other words, it was confirmed that 25 educational drones can be controlled within a range of 240m and the instructor can monitor them.

• The Korean Journal of Air & Space Law and Policy
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• v.32 no.1
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• pp.225-285
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• 2017

In regard to the regulations related to the RPA(Remotely Piloted Aircraft), which is sometimes called in other countries as UA(Unmanned Aircraft), ICAO stipulates the regulations in the 'RPAS manual (2015)' in detail based on the 'Chicago Convention' in 1944, and enacts provisions for the Rules of UAS or RPAS. Other contries stipulates them such as the Federal Airline Rules (14 CFR), Public Law (112-95) in the United States, the Air Transport Act, Air Transport Order, Air Transport Authorization Order (through revision in "Regulations to operating Rules on unmanned aerial System") based on EASA Regulation (EC) No.216/2008 in the case of unmanned aircaft under 150kg in Germany, and Civil Aviation Act (CAA 1998), Civil Aviation Act 101 (CASR Part 101) in Australia. Commonly, these laws exclude the model aircraft for leisure purpose and require pilots on the ground, not onboard aricraft, capable of controlling RPA. The laws also require that all managements necessary to operate RPA and pilots safely and efficiently under the structure of the unmanned aircraft system within the scope of the regulations. Each country classifies the RPA as an aircraft less than 25kg. Australia and Germany further break down the RPA at a lower weight. ICAO stipulates all general aviation operations, including commercial operation, in accordance with Annex 6 of the Chicago Convention, and it also applies to RPAs operations. However, passenger transportation using RPAs is excluded. If the operational scope of the RPAs includes the airspace of another country, the special permission of the relevant country shall be required 7 days before the flight date with detail flight plan submitted. In accordance with Federal Aviation Regulation 107 in the United States, a small non-leisure RPA may be operated within line-of-sight of a responsible navigator or observer during the day in the speed range up to 161 km/hr (87 knots) and to the height up to 122 m (400 ft) from surface or water. RPA must yield flight path to other aircraft, and is prohibited to load dangerous materials or to operate more than two RPAs at the same time. In Germany, the regulations on UAS except for leisure and sports provide duty to avoidance of airborne collisions and other provisions related to ground safety and individual privacy. Although commercial UAS of 5 kg or less can be freely operated without approval by relaxing the existing regulatory requirements, all the UAS regardless of the weight must be operated below an altitude of 100 meters with continuous monitoring and pilot control. Australia was the first country to regulate unmanned aircraft in 2001, and its regulations have impacts on the unmanned aircraft laws of ICAO, FAA, and EASA. In order to improve the utiliity of unmanned aircraft which is considered to be low risk, the regulation conditions were relaxed through the revision in 2016 by adding the concept "Excluded RPA". In the case of excluded RPA, it can be operated without special permission even for commercial purpose. Furthermore, disscussions on a new standard manual is being conducted for further flexibility of the current regulations.

• Tunnel and Underground Space
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• v.25 no.5
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• pp.462-469
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• 2015

This study carried out a topographic survey at a small-scale open-pit limestone mine in Korea (the Daesung MDI Seoggyo office) using a popular rotary-wing unmanned aerial vehicle (UAV, Drone, DJI Phantom2 Vision+). 89 sheets of aerial photos could be obtained as a result of performing an automatic flight for 30 minutes under conditions of 100m altitude and 3m/s speed. A total of 34 million cloud points with X, Y, Z-coordinates was extracted from the aerial photos after data processing for correction and matching, then an orthomosaic image and digital surface model with 5m grid spacing could be generated. A comparison of the X, Y, Z-coordinates of 5 ground control points measured by differential global positioning system and those determined by UAV photogrammetry revealed that the root mean squared errors of X, Y, Z-coordinates were around 10cm. Therefore, it is expected that the popular rotary-wing UAV photogrammetry can be effectively utilized in small-scale open-pit mines as a technology that is able to replace or supplement existing topographic surveying equipments.

• Journal of Microbiology and Biotechnology
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• v.25 no.11
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• pp.1944-1953
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• 2015

A novel alkaline protease from Streptomyces sp. M30, SapHM, was purified by ammonium sulfate precipitation, hydrophobic interaction chromatography, and DEAE-Sepharose chromatography, with a yield of 15.5% and a specific activity of 29,070 U/mg. Tryptic fragments of the purified SapHM were obtained by electrospray ionization quadrupole time-of-flight mass spectrometry. Nucleotide sequence analysis revealed that the gene sapHM contained 1,179 bp, corresponding to 392 amino acids with conserved Asp156, His187, and Ser339 residues of alkaline protease. The first 24 amino acid residues were predicted to be a signal peptide, and the molecular mass of the mature peptide was 37.1 kDa based on amino acid sequences and mass spectrometry. Pure SapHM was optimally active at 80℃ in 50 mM glycine-NaOH buffer (pH 9.0), and was broadly stable at 0-50℃ and pH 4.0-9.0. The protease relative activity was increased in the presence of Ni²⁺, Mn²⁺, and Cu²⁺ to 112%, 113%, and 147% of control, respectively. Pure SapHM was also activated by dimethylformamide, dimethyl sulfoxide, Tween 80, and urea. The activity of the purified enzyme was completely inhibited by phenylmethylsulfonyl fluoride, indicating that it is a serine-type protease. The K_m and V_max values were estimated to be 35.7 mg/ml, and 5 × 10⁴ U/mg for casein. Substrate specificity analysis showed that SapH was active on casein, bovine serum albumin, and bovine serum fibrin.