• Korean journal of aerospace and environmental medicine
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• v.30 no.2
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• pp.51-53
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• 2020

In commemoration of Vol. 30, Issue 2, our journal prepared three review articles, two original papers, and a case report. The first review analyzed aircraft accidents caused by pilots' fatigue and presented a protocol to measure their fatigue, such as primary background survey, subjective drowsiness/arousal evaluation, sleep and activity log, sleep data, and performance measurement. The second review analyzed shift work patterns and work characteristics that may affect the fatigue of aviation mechanics. Also, desirable work principles for aviation mechanics (restrictions on working hours, appropriate rest hours, and night shift restrictions) were presented. The third review discussed the effects that allergic rhinitis can have on pilots (drowsiness and decreased arousal) and introduced a safe treatment method that can prevent these adverse effects. In the first original article, the ratio of 'incompatible (non-fit)' result in aerospace medical examination among Korean aircraft pilots for the past five years was investigated by age group and the common causes of nonconformity were analyzed. In the second original article, the prevalence, mortality, prevalence according to age groups, and regional characteristics of severe febrile thrombocytopenia syndrome were compared and analyzed in Korea and Japan for the past five years. Finally, in the case report, the cases of a patient diagnosed as gastrointestinal stromal tumors who received surgical treatment and chemotherapy were discussed, and the results of the judgment were presented.

• Korean Journal of Family Social Work
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• no.59
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• pp.27-53
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• 2018

The objective of this study was to investigate the influence of family-related factors and age-friendly environment on intergenerational interaction in middle-aged group and the older adult group. Based on the results, this study is to suggest countermeasures for decreasing intergenerational interaction with the population aging. This study analyzed 260 sample participants aged from 45 to 64 and 399 sample participants aged 64 and more, categorizing them into middle-aged group and the older adult group respectively. The sample participants were taken from '2014 Survey on the Aged Society' and had at least one adult child aged over 18 at the time of participation. In order to identify the relationship between five sub-dimensions related to family, age-friendly environment and intergenerational interaction within the family in two age groups, t-test and multiple regression analysis were used. As a result, both two family-related factors had positive correlation with intergenerational interaction within the family. However, affective solidarity showed a higher significance in the middle-aged group and familism showed a higher significance in the older adult group. Among the sub-dimensions related to age-friendly environment, only personal opinion on age integration showed significance in the older adult group. This study provides several implications from the results.

• Korean Journal of Veterinary Research
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• v.29 no.4
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• pp.417-424
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• 1989

This study was conducted in order to observe the changes in cellular association of seminiferous tubules from 4 to 22 weeks of age and to obtain the cycle and relative duration of seminiferous epithelia from 24 weeks of age in male ducks. Fifety-five male ducks were used in the experiment and divided into 11 groups, consisting of 5 male ducks each, with 2 weeks intervals from 4 to 24 weeks of age. The results were summarized as follows: 1. The body and testes weight showed most rapid increase during 4 to 6 weeks and 18 to 22 weeks of age, respectively. The seminiferous tubules were obruptly enlarged in diameter of tubules during 18 to 22 weeks of age. 2. Gonocytes were seen from 4 to 6 weeks of age, however they were not observed as from 8 weeks of age. Both type Ap spermatogonia and type Ad spermatogonia occured from 8 to 12 weeks of age, while spermatocytes and spermatids were beginning to appear at 16 weeks and 18 weeks of age, respectively. Spermatozoa were first observed at 20 weeks of age. Full spermatogenic activity was completed at the age of 20 weeks. 3. Average paired weight of the testes in male ducks was 78g at 24 weeks of age and its ratio to the body weight was approximately 2.5 percent. 4. Average diameter of seminiferous epithelium at 22 weeks of age was $232{\mu}m$, and average numbers of Sertoli cell, spermatogonia, spermatocyte, spermatids and spermatozoa in the cross section of seminiferous epithelium were 15.30, 59.08, 41.78, 71.11 and 165.30, respectively. Spermatogonia and spermatids were classified into 2 and 4 types, respectively. 5. The cycle of the seminiferous epithelium could be divided into 5 stages at 24 weeks of age. The relative frequencies of stages from I to V were 13.5%, 25.0%, 22.3%, 20.6% and 18.7% respectively. Thus, establishment of spermatogenesis in male ducks were beginning to appear at 20 weeks of age.

• Research in Community and Public Health Nursing
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• v.12 no.2
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• pp.375-389
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• 2001

The purpose of this study was to evaluate the effect of Self-foot Reflex Massage (SRM) programme on the physical condition and anxiety level of hypertension workers. The research was designed in the pre and post-test. Sample test was done in five workers with essential hypertension. They were divided in two groups:- Group A and Group B. The Self-foot Reflex Massage (SRM) was applied three times a week for Group A and five times a week for Group B. The SRM was given in 40 minutes each time for 4 weeks from the 1st of January to the 30th of April in 2001. In order to evaluate the effect on SRM. blood pressure, total cholesterol, triglyceride, HDL cholesterol and LDL cholesterol were measured as physical parameters and state trait anxiety inventory was used twice each time between before and after the exercise. The collected data was analysed by Mann-Whitney test with SPSS program. The results were as follows: 1. Average age for the subjects were 39.8 (ranged from thirty-two to fifty-three) and average period of hypertension history was 42 months (ranged from twenty to eighty-four). 2. There was no significant difference between two examined groups in blood pressure. But, there was a significant difference in SRM of pre and post-test for two groups. 3. There was no significant difference in blood cholesterol between two groups and between pre and post-test. 4. State trait anxiety showed significant difference between pre and post-test except the results between two groups. This result suggests that SRM is effective on the decrease of systolic and diastolic pressure and the relief of state trait anxiety except for the blood cholesterol. Therefore, blood cholesterol is needed further evaluation in large subjects and longer period. Further research is regarded as necessary to evaluate and to compare the precise effects of SRM on the foot reflex massage (FRM) in anxiety.

• Clinical and Experimental Reproductive Medicine
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• v.24 no.2
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• pp.167-177
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• 1997

Oocyte donation program developed to reach the pregnancy in those patients suffering from premature ovarian failure or surgery induced menopause, particularly in their reproductive age. With technical advances and popularity of ART (assisted reproductive technology), the indication of oocyte donation program extended to low responders, and even to naturally menopaused patients that has led them quite successfully to getting in pregnancy. The purpose of this study was to evaluate which one is involved in the decline of fertility between the oocyte and uterine factor. One hundred five cycles of oocyte donation program were performed in 84 patients from Jan., 1993 to Dec., 1996. Oocytes were donated from healthy, young, fertile anonymous donors or relatives or infertile patients with supernumerary oocytes. The study population was divided into 3 groups according to the age of recipients. Group 1 was less than 35 years old, Group 2 was between 35 to 39 years old, and Group 3 was more than 39 years old. The results were as follows: The mean age of oocyte donor was $31.5{\pm}3.3$ (range; 25-36). The mean concentration of basal serum FSH and peak serum estradiol were not different among groups. The mean number of oocytes retrieved from donors, embryos transferred to recipients, and fertilization rate were not different among groups. The clinical pregnancy rate was 37.3% in Group 1, 31.6% in Group 2, and 31.6% in Group 3, respectively. The spontaneous abortion rate was 16.0% in Group 1, 16.7% in Group 2, and 16.7 in Group 3, respectively. The multiple pregnancy rate was 20.0% in Group 1, 16.7% in Group 2, 16,7% in Group 3, respectively, The implantation rate was 11.3% in Group 1, 10.3% in Group 2 and 10.0% in Group 3, respectively. All of the pregnancy outcomes were not different statistically among groups. In conclusion, endometrial receptivity does not seem to be impaired as age increases with transfer of good quality embryos and adequate endometrial preparation.

• Journal of Nutrition and Health
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• v.33 no.3
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• pp.304-313
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• 2000

This study was performed to assess diet quality in the postmenopausal women. The data of dietary intakes were obtained using food frequency questionnaires which were collected from 151 postmenopausal women in urban area. We evaluated nutrient intake and diet quality. Diet quality was assessed by NAR(nutrient adequacy ratio), FGIP(food group intake pattern), DDS(dietary diversity score), DVS(dietary variety score), FGS(food group score), DQI(diet quality index). Nutrient intakes of the subjects were close to Korean RDA. Nutrient composition of the diet(in percentage of total energy) was 64% carbohydrate, 15% protein, and 19% protein, and 19% total fat, that was close to 65 : 15 : 20. NAR of most nutrients, except vitamin A, E, were higher than 0.75 and MAR was 0.88. NAR and MAR of the subjects in theis study were higher than those of the subjects of rural area in other studies. The subjects who consumed the five food groups were 60.9%. The mean of DDS was 4.5. The subjects who consumed more than 61 dish items during a month were 61.5%. The mean of DVS was 62.4 and it was significantly higher in the elder age group. 67.6% of the subjects were below FGS of 12. The mean of FGS was 10.6 and few subjects consumed serving numbers of each food groups which were recommended for Koreans. 55.0% of the subjects were DQI scores of 0, 1, and 2. The mean of DQI was 2.3 and few subjects followed the five dietary guidelines for Korean.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.4
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• pp.570-575
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• 2002

Effects of active immunization against native 14-mer somatostatin (SRIF, somatotropin releasing inhibiting factor) and its two 14-mer-somatostatin analogues on the milk production in rat mammary cells were studied. Native SRIF, Tyr11-somatostatin (Tyr11-SRIF), and D-Trp8, D-Cys14-somatostatin (Trp8Cys14-SRIF) were conjugated to bovine serum albumin (BSA) for immunogen preparation. Twenty-four female Sprague-Dawley rats were divided into four groups and immunized against saline (Control), SRIF, Tyr11-SRIF, and Trp8Cys14-SRIF at five weeks of age. Booster immunizations were performed at 7, 9, and 11 weeks of age. SRIFimmunized rats were mated at 10 weeks of age. The blood and mammary glands were collected at day 15 post-pregnancy and -lactation. To measure the amount of milk protein synthesis in the mammary gland, mammary cells isolated from the pregnant and the lactating rats, were cultured in the presence of $^3H$-lysine. No significant differences in growth performance, concentration of growth hormone in the circulation, and the amount of milk protein synthesis were observed among the groups. Inductive levels of serum anti-SRIF antibody in the SRIF and Tyr11-SRIF groups but not in the Trp8Cys14-SRIF group, were significantly higher than that of the control group during the pregnancy and lactation periods. The result suggests that active immunization against native 14-mer SRIF and Tyr11-SRIF was able to induce anti-SRIF antibodies, but did not affect the milk protein synthesis.

• Journal of Ginseng Research
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• v.43 no.1
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• pp.58-67
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• 2019

Background: Diabetic neuropathy is one of the most devastating ailments of the peripheral nervous system. Neuropathic pain develops in ~30% of diabetics. Here, we examined the suppressive effect of GS-KG9 on neuropathic pain induced by streptozotocin (STZ). Methods: Hyperglycemia was induced by intraperitoneal injection of STZ. Rats showing blood glucose level > 250 mg/dL were divided into five groups, and treatment groups received oral saline containing GS-KG9 (50 mg/kg, 150 mg/kg, or 300 mg/kg) twice daily for 4 wk. The effects of GS-KG9 on pain behavior, microglia activation in the lumbar spinal cord and ventral posterolateral (VPL) nucleus of the thalamus, and c-Fos expression in the dorsal horn of the lumbar spinal cord were examined. Results: The development of neuropathic pain began at Day 5 and peaked at Week 4 after STZ injection. Mechanical and thermal pains were both significantly attenuated in GS-KG9-treated groups from 10 d after STZ injection as compared to those in the STZ control. GS-KG9 also repressed microglia activation in L4 dorsal horn and VPL region of the thalamus. In addition, increase in c-Fos-positive cells within L4 dorsal horn lamina I and II of the STZ control group was markedly alleviated by GS-KG9. Conclusion: These results suggest that GS-KG9 effectively relieves STZ-induced neuropathic pain by inhibiting microglial activation in the spinal cord dorsal horn and VPL region of the thalamus.

• Journal of the Korean Society of Safety
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• v.24 no.5
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• pp.92-100
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• 2009

This study evaluated the effects of the syllable number(one, two), font type(gothic, myung), color contrast (black on white, white on black), display type(paper, LCD), age(20s, 60s) and character size(2~80pt) on the Korean characters' legibility. Total twenty subjects from two age groups (20s: n=10, 60s: n=10, five male and five female in each group) participated in the legibility test. A target panel was presented in the distance of 50 cm, and subjects conducted a reading tests for, in total, 16 treatment conditions (full combination of syllable number, font type, color contrast and display type). Results showed that two-syllable words revealed better legibility than one-syllable character. The main effects of the age, display type, font type, color contrast, and character size were statistically significant(p<0.01). Paper showed better legibility than LCD, particularly in the 20s and in the character sizes of less than 9pt. Gothic revealed more correct answers than Myung, particularly in the 60s, paper, and white on black conditions. It is expected that these results can provide basic data for the determination of the Korean characters' minimum legible size standards. For example, the minimum legible size for the Gothic and black on white characters presented in the paper should be 5pt for 20s and 1lpt for 60s if the 75% correct reading(3 correct answers in this study) was applied for the legibility criterion.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.17 no.3
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• pp.140-146
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• 2014

Purpose: The etiology of acute gastroenteritis (AGE) has changed since the introduction of the rotavirus vaccination. The aim of this study was to clarify which common pathogens, both bacterial and viral, are currently causing AGE in infants. Methods: Infants with acute diarrhea were enrolled. We tested for 10 bacterial pathogens and five viral pathogens in stool specimens collected from infants with AGE. The clinical symptoms such as vomiting, mucoid or bloody diarrhea, dehydration, irritability, and poor oral intake were recorded, and laboratory data such as white blood cell count and C-reactive protein were collected. The clinical and laboratory data for the cases with bacterial pathogens and the cases with viral pathogens were compared. Results: Of 41 total infants, 21 (51.2%) were positive for at least one pathogen. Seventeen cases (41.5%) were positive for bacterial pathogens and seven cases (17.1%) were positive for viral pathogens. Staphylococcus aureus (13 cases, 31.7%) and Clostridium perfringens (four cases, 9.8%) were common bacterial pathogens. Norovirus (five cases, 12.2%) was the most common viral pathogen. Fever and respiratory symptoms were common in the isolated viral infection group (p=0.023 and 0.044, respectively), whereas other clinical and laboratory data were indistinguishable between the groups. Conclusion: In our study, S. aureus (41.5%) and norovirus (12.2%) were the most common bacterial and viral pathogens, respectively, among infants with AGE.