• Journal of Preventive Medicine and Public Health
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• v.30 no.3 s.58
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• pp.577-584
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• 1997

Validation and Standardization of neurobehavioral instrument in Korean occupational setting has not been studied ever. This study tried to validate the newly developed computerized psychomotor tests, Neurobehavioral Tests for Occupational Screening (NTOS). Male patients with Parkinson's disease(n=12) and male workers who never exposed to occupational neurotoxic materials and didn't have neurologic disease(n=21), performed some tests from NTOS; simple reaction time, choice reaction time(2 choice), and finger tapping(both hands). In simple analysis, difference between patient group and worker group was significantly great. Adjusted for age and education years, simple reaction time and finger tapping(both hand) were statistically significantly different between two groups(p<.05). Choice reaction time was also different(p<.1) but error frequency of choice reaction time test was not. Generally, this results showed NTOS could detect impairment of psychomotor function. But insensitive results of choice reaction time was partly due to small sample size and confounding variables and so required future study and refinement at improvement of NTOS.

• Environmental Analysis Health and Toxicology
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• v.28
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• pp.15.1-15.8
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• 2013

Objectives The aim of this study was to determine the association between low-level mercury exposure and neurobehavioral functions in adults living in coastal regions of Korea. Methods We selected 172 adults aged 20-65 years living in a city in the coastal region of Korea. A sociodemographic survey was conducted, mercury levels in the blood, urine, and hair were measured, and the associations according to computerized neurobehavioral tests were determined using univariate analysis. After adjustment for associated variables, a multivariate linear regression analysis was performed. Results The geometric mean mercury levels in the blood, urine, and hair were $5.41{\mu}g/L$ (range, $0.00-15.84{\mu}g/L$), $1.17{\mu}g/g$-creatinine (range, $0.00-32.86{\mu}g/g$-creatinine), and 1.37 mg/kg (range, 0.42-6.56 mg/kg), respectively. Variables that were associated with simple reaction time according to the neurobehavioral test results were age and urine mercury level. Variables associated with choice reaction time were the recent use of Korean traditional medicine and urine mercury level. Variables associated with the right-hand finger tapping speed test were age, gender, smoking behavior, education level, monthly household income, and urine mercury level. Variables associated with the left-hand finger tapping speed test were age, gender, education level, and urine mercury level. After adjustment for associated variables, there was no significant association between urine mercury level and simple reaction time (${\beta}=25.96$; p =0.47), choice reaction time (${\beta}=50.37$; p =0.32), or the number of left-hand finger taps (${\beta}=-1.54$; p =0.21). However, urine mercury level was significantly associated with the number of right-hand finger taps (${\beta}=-3.86$; p =0.01). Conclusions We found no evidence that low-level mercury exposure in adults is associated with deficits in neurobehavioral functions. A longer follow-up study is required to confirm this conclusion.

• Archives of Plastic Surgery
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• v.36 no.3
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• pp.318-321
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• 2009

Purpose: The bony mallet finger injury is generally managed by conservative treatments, but operative treatments are needed especially when the fractures involve above 30% of articular surface or distal phalanx is accompanied by subluxation in the volar side. This is the reason they often result in chronic instability, articular subluxation and unsatisfactory cosmetic. In this report, We describe new method using the hook plate as an operative treatment of Mallet finger deformity. Methods: Among 13 patients with Mallet finger deformity who came from February 2006 to February 2008, six patient were included in surgical indication. Under local anesthesia, H or Y type incision was made at the DIP joint area. After the DIP joint extension, the hook plate was put on the fracture line, and one self tapping screw was used for fixation. 2 hole plate which was one of the holes in 1.5 mm diameter was cut in almost half and bended through approximately $100^{\circ}$. Results: In all six cases which applied the hook plate, complications such as loss of reduction or nail deformity were not seen. In only one patient, hook pate was removed due to inflammatory reaction after surgery. At 2 weeks after operation, active motion of DIP joint was performed. The result was satisfactory not only cosmetically but also functionally. At 6 weeks after operation, the range of motion of DIP joint was average $64^{\circ}$. Conclusion: The purpose of the operative treatment for mallet finger deformity using the hook plate is to provide anatomical reduction with rigid fixation and to prevent contracture at the DIP joint. While other operations take 6 weeks, the operation using the hook plate begins an active motion at 2 weeks after operation. Complication rate was low and the method is rather simple. Thus, the operation using the hook plate is recommended as a good alternative method of the mallet finger deformity treatment.

• Journal of the Ergonomics Society of Korea
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• v.6 no.1
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• pp.3-8
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• 1987

This paper develops a statistical mode which estimates mental and physical loads of light work from sinus arrhythmia (SA) scores. During experiments, various levels of mental and physical loads (respectively scored by information processing and finger tapping rates) were imposed on subjects and SA scores were measured from the subjects. Two methods were used in developing workload estimation model. One is an algebraic inverse function of a multivariate regression equation, where mental and physical loads are independent variables and SA scores are dependent variables. The other is a statistical multivariate inverse regression. Of the two methods, inverse function resulted in larger mean squqre error in predicting mental and physical loads. Hence, inverse regression model is recommended for precise workload estimation.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.31-31
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• 2003

목적： 통증에 대한 fMRI 연구에 있어서 differential-regression-analysis (DRA) 기법을 사용하여 대뇌 피질에서 통증 처리에 관련된 영역의 순시적인 변화를 관찰하였다. 대상 및 방법： 우선 통증과 일반적인 감각자극과의 생리학적 차이를 밝히기 위해 운동 (finger tapping) 및 시각 (flickering light) 자극 실험이 선행되었다. 통증 유발을 위해서는 50C에서 52C의 뜨거운 물을 이용한 온도자극이 왼손의 검지와 중지에 30초 동안 가해졌다. fMRI 실험은 Marconi (Philips) 1.5 T scanner를 이용하여 gradient echo EPI sequence(TR / TE / FA = 3 sec / 35 msec / 90)로 수행되었다. 감각자극과 통증자극에 대한 반응의 동적인 변화를 관찰하기 위하여 fMRI 결과 분석에 기존의 box-car function과 DRA 기법이 사용되었다.

• Proceedings of the KAIS Fall Conference
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• 2011.12a
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• pp.251-254
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• 2011

본 논문에서는 가속도 센서를 이용한 손가락의 움직임을 인식하는 손가락 동작 인식 장치와 블루투스 통신을 통하여 전송된 손가락의 동작정보를 이용하여 스마트폰에서 문자 입력이 가능한 문자입력 인터페이스를 구현하였다. 중환자실에는 의식은 있으나 말을 못하고, 손을 자유롭게 움직일 수 없는 상태의 환자들에게 의사나 가족과의 보다 나은 의사소통을 통해 스마트폰을 활용한 인터페이스를 개발하여 오진 및 사고를 방지하고 환자의 상태를 이해하는데 도움을 줄 수 있는 환경을 구축하였다.

• Journal of Yeungnam Medical Science
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• v.14 no.1
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• pp.183-196
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• 1997

An experimental study was performed to investigate. The subjects drank (0.5g/kg ethanol and performed 7 items of SPES(simple reaction time, color word stress, digit classification, finger tapping speed, numerical ability, symbol digit coding, memory digit span). 20 students of medical college participated in the study during August, 1996. After ethanol intake, performance of 4 items(simple reaction time, digit classification, finger tapping speed, symbol digit coding) significantly showed to be decreased. The function of perception-response speed and steady movement were found to be more sensitive to ethanol than that of short-term memory, numerical ability and specification of color. No significant association were found between smoking, alcohol drinking, BMI(body mass index) and the effects of ethanol on neurobehavioral performance.

• Sleep Medicine and Psychophysiology
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• v.1 no.1
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• pp.76-86
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• 1994

Objectives: This research was performed in order to observe the neuropsychological implication and functional anatomical source of event related potentials(ERP) by studying of correlations between event related potentials and neuropsychological tests. Methods: The latency and voltage of P100 of visual evoked potential (VEP), and N120 and P300 of event related potentials were studied in 56 patients and their correlations with neuropsychological tests were computed. Results: The tests showing significant correlation with latency P100 were visual continous performance test(VCPT) and contingent continous performance test(CCPT) without any significant correlation with voltage of P100. In latency of N120 category test and verbal IQ of KWIS showed significant correlation, and in voltage of N120, finger tapping test, VCPT, CCPT and digit symbol test displayed significant correlations. The latency of P300 had significant correlation with trail making A test and Stroop test. In the voltage of P300 significant correlations were shown with trail making B test, digit symbol test and Wechsler memory scale, finger tapping test, stroop test, VCPT and CCPT. Conclusion : N120 may be considered to reflect the function of medial frontal lobe and P300 may be considered to be developed from the subcortical connection of medial temporal lobe, hippocampus, thalamus, basal ganglia and medial frontal lobe.

• The Journal of Internal Korean Medicine
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• v.39 no.2
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• pp.147-153
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• 2018

Objective: The purpose of this case report is to evaluate the effect of electroacupuncture on Pal-sa (EX-UE9) for unilateral motor disturbance of the hand after cerebral infarction. Methods: One patient with unilateral motor disturbance of the hand following cerebral infarction (right basal ganglion and corona radiata) was treated with acupuncture, herbal medication, and electroacupuncture on Pal-sa (EX-UE9) once daily from June 30, 2016 to July 4, 2016. We evaluated improvement using the Box and Block Test (BTT) and 10-seconds Test, including the Finger Individual Movement Test (FIMT), the Hand Pronation and Supination Test (HPST), and the Finger Tapping Test (FTT). Results: After five days of treatment, increase of FIMT and FTT scores was observed after electroacupuncture on Pal-sa (EX-UE9). However, no increase was observed in BBT or HPST scores. Conclusions: This study suggests that electroacupuncture on Pal-sa (EX-UE9) can help treat motor disturbance of the hand after cerebral infarction.

• Investigative Magnetic Resonance Imaging
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• v.21 no.2
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• pp.91-96
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• 2017

Purpose: To describe technical methods for functional magnetic resonance imaging (fMRI) study with arterial spin labeling (ASL) compared to blood oxygenation level-dependent (BOLD) technique and discuss the potential of ASL for research and clinical practice. Materials and Methods: Task-based (n = 1) and resting-state fMRI (rs-fMRI) (n = 20) were performed using ASL and BOLD techniques. Results of both techniques were compared. Results: For task-based fMRI with finger-tapping, the primary motor cortex of the contralateral frontal lobe and the ipsilateral cerebellum were activated by both BOLD and ASL fMRI. For rs-fMRI of sensorimotor network, functional connectivity showed similar results between BOLD and ASL. Conclusion: ASL technique has potential application in clinical and research fields because all brain perfusion imaging, CBF measurement, and rs-fMRI study can be performed in a single acquisition.