• Biomolecules & Therapeutics
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• 제31권5호
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• pp.573-582
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• 2023

Muscle atrophy is characterized by the loss of muscle function. Many efforts are being made to prevent muscle atrophy, and exercise is an important alternative. Methylglyoxal is a well-known causative agent of metabolic diseases and diabetic complications. This study aimed to evaluate whether methylglyoxal induces muscle atrophy and to evaluate the ameliorative effect of moderate-intensity aerobic exercise in a methylglyoxal-induced muscle atrophy animal model. Each mouse was randomly divided into three groups: control, methylglyoxal-treated, and methylglyoxal-treated within aerobic exercise. In the exercise group, each mouse was trained on a treadmill for 2 weeks. On the last day, all groups were evaluated for several atrophic behaviors and skeletal muscles, including the soleus, plantaris, gastrocnemius, and extensor digitorum longus were analyzed. In the exercise group, muscle mass was restored, causing in attenuation of muscle atrophy. The gastrocnemius and extensor digitorum longus muscles showed improved fiber cross-sectional area and reduced myofibrils. Further, they produced regulated atrophy-related proteins (i.e., muscle atrophy F-box, muscle RING-finger protein-1, and myosin heavy chain), indicating that aerobic exercise stimulated their muscle sensitivity to reverse skeletal muscle atrophy. In conclusion, shortness of the gastrocnemius caused by methylglyoxal may induce the dynamic imbalance of skeletal muscle atrophy, thus methylglyoxal may be a key target for treating skeletal muscle atrophy. To this end, aerobic exercise may be a powerful tool for regulating methylglyoxal-induced skeletal muscle atrophy.

• 한국전문물리치료학회지
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• 제9권3호
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• pp.67-76
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• 2002

We report the reorganization of motor network resulted from intensive unilateral coordination training and the effect of cross education on the untrained side in patient with traumatic brain injury using functional magnetic resonance imaging (fMRI). A 22 year-old male patient who had suffered from diffuse axonal injury for 58 months showed coordination deficit in the left hand at initial examination. Intensive motor training including complex finger movements and coordination activities using a metronome was introduced to the patient 4 hours per day for a week. FMRI was performed on a 3T ISOL Forte scanner. All functional images were analyzed using SPM-99 software. Hand function was improved after training not only in the trained left hand, but also in the untrained right hand. There was no activation in the right primary motor area (M1) during left hand movement before training whereas robust activation of left M1 was demonstrated by the right hand movement. Profuse activation of bilateral prefrontal lobes was seen during both hand movements before training. After training of left hand, right M1 became prominently activated during the left hand motion. The activation of bilateral prefrontal lobes disappeared after training not only for the left hand movement but also for the right, which clearly demonstrated the effect of cross education. This case report demonstrated the learning-dependent reorganization of the M1 and the effect of cross education.

• 재활간호학회지
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• 제13권1호
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• pp.44-52
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• 2010

Purpose: The purposes of this study were to explore changes in pain, mood and the level of posttrauma risk for 2 weeks after acute hand microsurgery and determine predictors of pain 2-week after microsurgery. Method: Using a sample of 84 patients with hand microsurgery, pain, mood, and posttrauma risk were measured by the Brief Pain Inventory-Korea, the modified Profile of mood states, and the Posttrauma risk checklist at 1-day, 1-week and 2-week post-microsurgery. Repeated measures ANOVA and Multiple regression analysis were conducted to evaluate changes in pain, mood, and posttrauma risk over time after the surgery and determine predictors of pain 2-week after the surgery. Results: Pain significantly decreased (F=63.22, p<.001), mood significantly improved (F=41.04, p<.001) 2 weeks after microsurgery and interestingly, posttrauma risk significantly decreased from baseline to 1-week microsurgery but increased at 2-week after microsurgery (F=24.66, p<.001). Approximately 57% of the variance of pain 2-week post-microsurgery was explained by pain at 1-week post-microsurgery, mood and the numbers of injured fingers. Conclusion: The findings suggest the pain control for 1week after acute surgery being critical and posttrauma rehabilitation of injured finger being necessary. Developing nursing interventions is urgently needed to help individuals with impending hand microsurgery.

• 한국전문물리치료학회지
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• 제8권2호
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• pp.55-63
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• 2001

For spinal flexibility measurements to be meaningful to clinicians or researchers, they must have a normative information and an understanding of how different variables affect spinal range of motion (ROM). Normal spinal ROM measurements are influenced to differing degrees by many factors. These factors include age, gender, time of day, leisure activities, previous history of low back pain, warming up, and the techniques with which normative data are collected. The additional variables of standing height, ratio of standing height to sitting height, and obesity had not been previously studied extensively and were shown to have a significant effect on flexibility in the sagittal plane. These relationship cannot be explained easily. Thus, the purpose of this study was to determine the relationship between spinal flexibility and individual factors (weight, standing height, and ratio of standing height to sitting height) that influence it. Fifteen healthy subjects between the ages of 20 and 27 years were studied. Two physical therapists measured independently the spinal forward bending ROM in the sagittal plane by Remodified Schober test and Finger-to-floor test. In order to determine the statistical significance of the result the Pearson's correlation was applied at the .05 level of significance. The results of this study were as follows: 1) Significant relationship was not identified between spinal flexibility and weight. 2) Significant relationship was not identified between spinal flexibility and standing height. 3) Significant relationship was not identified between spinal flexibility and ratio of standing height to sitting height.

• Journal of Korean Neurosurgical Society
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• 제58권5호
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• pp.491-493
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• 2015

The upper trunk of the brachial plexus is the most common area affected by neuralgic amyotrophy (NA), and paresis of the shoulder girdle muscle is the most prevalent manifestation. Posterior interosseous nerve palsy is a rare presentation in patients with NA. It results in dropped finger on the affected side and may be misdiagnosed as entrapment syndrome or compressive neuropathy. We report an unusual case of NA manifested as PIN palsy and suggest that knowledge of clinical NA phenotypes is crucial for early diagnosis of peripheral nerve palsies.

• The Journal of Korean Physical Therapy
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• 제15권4호
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• pp.140-150
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• 2003

The purpose of study was to compare change of blood volume on upper limb of stimulus site on interferential current therapy. Twenty university student(twelve females. eight males :mean aged 23.08) with health condition participated this study MP150 system(biopac system) was used to measured blood volume. PPG senser was located thrum finger end The obtain result are as follows. 1. The result of this study were following that stimulate time blood volume were significantly increased sympathetic stimulation group compared with muscle stimulation group(p<.05). 2. The result of this study were following that stimulate time blood volume were significantly increased sympathetic stimulation group compared with muscle stimulation group(p<.05). 3. The result of this study were following that sympathetic stimulation group were significantly increased stimulate time blood volume compared with stimulate time blood volume(p<.05). 4. The result of this study were following that muscle stimulation group were significantly increased stimulate time blood volume compared with stimulate time blood volume(p<.05).

• 대한한방소아과학회지
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• 제22권1호
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• pp.59-67
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• 2008

Objectives This study is to investigate the effects of oriental medical treatment for traumatic cerebral infarction. Methods We treated the patients with herbal medicine, acupuncture, aroma therapy, rehabilitation, and we evaluated these cases with Activity Index. Results There are some improvements in each patients, such as manual muscle power, finger apraxia after oriental medical treatments. Conclusions We report a change for the better effect of oriental medical treatment on this case. The more clinical studies of oriental medical treatment for traumatic cerebral infarction are needed.

• The Journal of Korean Physical Therapy
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• 제14권3호
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• pp.345-354
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• 2002

A Study of Clinical Application of the Connective Tissue Massage General massage is termed kneading and rubbing. It will bring the effect of blood volume and cardiovascular reaction. Connective tissue massage is a diagnostic and treatment method. But the general massage has not diagnostic aspect. Connective tissue massage techniques are stimulating and stretching the LCT, mast cell, collagenous fiber, fascia, skin, muscle and nerve tissue. Diagnostic aspects of connective tissue massage are visible investigation, manual investigation, and stroking on the reflex zone. CTM do stroking with 3, 4th finger tips on the whole body for the treatment.

• 근관절건강학회지
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• 제8권2호
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• pp.302-322
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• 2001

This study was carried out in order to examine the health status of arthritis patients living in K city of southern part of Korea. The data were collected with AIMS2 instrument from 56 subjects who were asked to complete the questionnaire by the trained surveyor. The AIMS2 has been approved useful instrument for assessing the outcome of various treatments and programs in rheumatic diseases. The component variables of the AIMS2 are Mobility, Walking and Bending, Hand and finger function, Arm function, Self-care tasks, Household tasks, Social activity, Support from family and friends, Arthritis pain, Work, Mood, Level of tension, The total number of items of AIMS 2 are 78. The results are as follows: The average age of the subjects was 58 years old and no gender difference. The mean scores of the 12 sub-concepts of AIMS2 are 15.0 of mobility, 12.16 of walking and of bending, 9.32 of hand and finger function, 9.03 of arm function, 13.53 of self-care tasks, 10.19 of household tasks, 15.09 of social activity, 19.58 support from family and friends, 13.82 of arthritis pain, work, 14.85 of level of tension, 15.12 of mood. The Cronbach Cronbach $\alpha$. is 0.72-91 for RA patients and 0.74-96 for OA patients. This results showed that the health status of Arthritis patients at home in K-city was almost not so serious, but the level of tension and mood were quite higher than the average score. Considering the results of this particular subjects, an appropriate rehabilitation program should be developed and implemented.

• 대한정형도수물리치료학회지
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• 제15권1호
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• pp.58-63
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• 2009

Purpose: The purpose of this study is to figure out that the scapular stability exercise on unstable position can effect on the pain relief of the patient with lateral epicondylitis. Methods: The subject was 35 year old male, diagnosed as lateral epicondylitis. This patient was controled to do scapular stability exercise with crawling position on unstable surface, changing elbow movement from flexion to extension for 4 weeks, 5 times a week, 20 times in total. We used VAS to find the degree of pain and Cozen's test, Mill's test and Resisted middle finger test were determined for the measurement of epicondylitis changed. Results: The following is the result of this study. 1. Pain on lateral epicondylitis was relived from VAS 7 to VAS 0. 2. There were improvements that the results of tests for epicondylitis, Cozen's test, Mill's test and Resisted middle finger test, changed positive into negative signs. Conclusion: The result of this study indicates that the application scapular stability exercise on the unstable surface to the patient with lateral epicondylitis can relief the pain degree on the lateral epicondylitis and be used as one of lateral epicondylitis treatments.