• Title/Summary/Keyword: fight or flight

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Nutrition and Gastrointestinal Physiology (토끼의 영양과 소화생리)

  • 박천식
    • Journal of the korean veterinary medical association
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    • v.37 no.8
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    • pp.706-713
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    • 2001
  • 자연적인 서식지에서 토끼는 번번히 육식 동물의 먹이가 된다. 이들의 일차적이고 우선적인 생존 반응은 발견을 피하기 위한 노력으로 조용히 있는 것이다. 토끼는 폭발적인 속도를 빠르게 낼 수 있고 짧은 거리에서 즉시 방향을 바꿀 수 있도록 가벼운 뼈, 작은 앞다리, 강력하고 잘 발달된 뒷다리를 가졌을 뿐만 아니라, 예민한 청각과 즉각적인 후각을 발달시킴으로써 'fight or flight(적자생존)'로 적응해왔다. 이런 생존 반응은 욕구가 없어진 것으로 나타나는 대부분의 집토끼에도 여전히 존재하지만, 이런 토끼들은 장애에 대해 반응이 불완전하고 변화에 쉽게 스트레스를 받는다. 스트레스를 받은 동물은 일차적으로 anorexia와 용변의 빈도와 일관성에 변화를 유발하는 건강, 생식, 행동적인 문제에 더욱 민감하다.

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3D-QSAR Studies of 8-Substituted-2-aryl-5-alkylaminoquinolines as Corticotropin-releasing Factor-1 Receptor Antagonists

  • Nagarajan, Santhosh Kumar;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.8 no.3
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    • pp.176-183
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    • 2015
  • Corticotropin-releasing actor receptors (CRFRs) activates the hypothalamic pituitary adrenal axis, one of the 2 parts of the fight or flight response to stress. Increased CRH production has is associated with Alzheimer's disease and major depression and hypoglycemia. In this study, we report the important structural and chemical parameters for CRFR inhibitors using the derivatives of 8-substituted-2-aryl-5-alkylaminoquinolines. A 3D QSAR study, Comparative molecular field analysis (CoMFA) was performed. The best predictions were obtained for the best CoMFA model with a $q^2$ of 0.607 with 6 components and $r^2$ of 0.991. The statistical parameters from the generated CoMFA models indicated that the data are well fitted and have high predictive ability. The contour map resulted from the CoMFA models might be helpful in the future designing of novel and more potent CRFR derivatives.

Comparative Molecular Similarity Indices Analysis (CoMSIA) of 8-substituted-2-aryl-5-alkylaminoquinolines as Corticotropin-releasing factor-1 Receptor Antagonists

  • Nagarajan, Santhosh Kumar;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.9 no.4
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    • pp.241-248
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    • 2016
  • Corticotropin-releasing factor receptors (CRFRs) activate the hypothalamic-pituitary-adrenal axis, which is an integral part of the fight or flight response to stress. Increase in CRH level is observed in Alzheimer's disease and major depression and hypoglycemia. Here, we report on the relevant physicochemical parameters required for the CRFR inhibitors. Comparative molecular similarity indices analysis (CoMSIA) was performed with the derivatives of 8-substituted-2-aryl-5-alkylaminoquinolinesas CRFR inhibitors. The best predictions were obtained for the best CoMSIA model with a $q^2$ of 0.576 with 6 components and $r^2$ of 0.977. The statistical parameters from the generated CoMSIA models indicated that the data are well fitted and have high predictive ability. CoMSIA contour maps could be useful in the designing of more potent and novel CRFR derivatives.

Forms of Expression of Angry Voters and Sad Voters: The Effects of Discrete Emotions and Emotional Expression on the Voting Participation through Approach-Avoidance Action Tendencies

  • Shin, Hye-kyung;Baek, Young Min
    • Asian Journal for Public Opinion Research
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    • v.2 no.4
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    • pp.248-278
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    • 2015
  • Despite the proliferation of studies on emotion, little attention has been paid to the effects of discrete emotion on political participation. Using a representative survey conducted on a sample of South Korean citizens in the aftermath of the Sewol ferry accident, the current survey explored how anger and sadness, as well as the ways people express those emotions, influence the orientation of their response in social environments and, ultimately, their voting intention. The results partially supported the discrete effects of sadness and anger in eliciting reactions of approach or avoidance. Anger was found to provoke an approach action tendency in independent voters and supporters of the opposition, while also eliciting an avoidance action tendency with a varying effect size across all three groups of respondents. Sadness also prompted an approach action tendency in independents and supporters of the incumbent party, while it manifested a negative association with the avoidance action tendency in supporters of the opponent party. An interpretation of the findings and proposed directions for future research are presented.

The Diversity of Reproductive and Foraging Behaviors on Breeding Season of Eurasian Oystercatcher (Haematopus ostralegus) (검은머리물떼새의 번식행동 및 번식기 섭식행동의 다양성)

  • Yoon, Moo-Boo
    • The Korean Journal of Ecology
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    • v.27 no.6 s.122
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    • pp.383-390
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    • 2004
  • This study was conducted in three sites, Si-Hwa Lake, Dongman and Seoman island and Janguyeop island, from march, 1999 to september, 2002. The behaviors of pre-breeding season, territorial behaviors, reproductive ecology, foraging sites and behaviors, and the competition of reproduction and foods between intraspecific or interspecific of Eurasian Oystercatcher (Haematopus ostralegus) were observed in each studying sites. The breeding of Eurasian Oystercatcher started on the middle of April in Si-Hwa Lake and on the middle of May in Dongman and Seoman island and Janguyeop island. For intension of pair bond on pre-breeding season, Eurasian Oystercatcher foraged with pair and behaved male-female chasing flight behavior. The pair foraged with male and female before copulation. If other pairs and individuals approached in feeding site of pair, this pair attacked them with piping calling and intruder chasing flight. If continuos serial behaviors were not observed, the discrimination of male-female chasing flight and intruder chasing flight was difficult. Territorial behaviors classified four types; butterfly flight, calling behavior, chasing behavior, fight behavior. The important foraging sites in Si-Hwa Lake are the land place in Daeboo island, tidal flat of Bangameori, tidal flat a front of a stationary net for catching fishes and tidal flat a front of a view station for bird watching. Eurasian Oystercatcher foraged at tidal flat on low water of the tide and foraged at feeding sites near island on flood tide in Dongman and Seoman island. Eurasian Oystercater in Janguyeop island usually foraged feeding sites near island, because water level was not different between low water of the tide and flood tide. Eurasian Oystercatcher competed on foods of intraspecific and interspecific. They chased for taking foods by force in feeding sites and drove out intruders in feeding sites. The foods interspecific competition happened with Black-tailed Gull (Larus crassirostris). Eurasian Oystercatcher was robbed of foods and attacked by Black-tailed Gull. The individual of food competition with Black-tailed Gull was low foods intake rate comparison with other feeding sites and this individual flied out other feeding sites.

Adaptive Expertise in Pilot Situation Awareness: Comparison of Expert and Novice Instrument Flight Performance (조종사 상황인식의 적응적 전문성: 전문가와 초보자의 계기비행 수행 비교)

  • Sohn, Young-Woo;Lee, Kyung-Soo
    • Science of Emotion and Sensibility
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    • v.12 no.1
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    • pp.55-64
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    • 2009
  • Previous research has mainly investigated the characteristics of expertise by using typical and routine tasks. This research to overcome these limitations included non-routine task situations and observed expert and novice pilots' situation awareness (SA) performance in routine and non-routine situations. Additionally, whether the ability to aware or perceive the environmental information in limited time varies with the level of expertise was tested. To this end, $2^*2^*2$ mixed factorial design was employed, including expertise (novice/expert) as a between-subjects variable and normality of fight situation (routine/non-routine) and stimulus display time (long/short) as within-subjects variables. As results, there was no performance difference in routine situations between experts and novices, while experts significantly outperformed novices in non-routine situations. When the display time became shorter, overall SA accuracy was decreased for both experts and novices, whereas experts' performance remained significantly higher than novices in short and long conditions. When we examined the interaction between the normality of fight situation and stimulus display time, there was no difference between experts and novices in routine situations for both short and long conditions. In non-routine situations, however, experts' SA accuracy was significantly higher than novices both in short and long conditions. Overall, non-routineness of flight situation does not have any impact on SA performance of experts, while it has a critical impact on SA performance of novices.

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Research on Actual Usage and Satisfaction of ROKAF Fighter Pilot's Flight Duty Uniform (공군 전투조종사 비행복 착용특성 및 만족도 조사)

  • Lee, Ah Lam;Nam, Yun Ja;Hong, Yu Hwa;Im, Sojung;Lim, Chae Keun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.40 no.4
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    • pp.669-684
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    • 2016
  • This study investigates Korean fighter pilot's usage and satisfaction of a flight duty uniform (FDU). The survey was conducted from October 2014 to March 2015 using Focus Group Interview (FGI) and questionnaires. FGI collected qualitative data about duty and requirements; subsequently, surveys were performed to collect quantitative data about wearing conditions and satisfaction with FDU. The results of the FGI and the questionnaire were as follows. Type of pilot duty was divided into two parts, flight duty and ground duty. It is important to consider duties as well as factors related to survival when developing FDU. According to anthropometric data and wearing size, the basic size for apparel grading should be changed from actual size, 'M95XL' to 'M100L'. It is also necessary to improve the whole sizing system. Further studies about body form changes in pilot's movement are needed to improve mobility because the respondents perceived some restrictions at several body parts in movement with the coverall uniform. Summer FDU had a low satisfaction level in vent hole function and appearance. Furthermore, protection problems in the vent hole were also an issue. Making a seasonal classification of FDU fabric will be more effective than a vent hole to increase a pilot's thermal satisfaction. Respondents had a passive stance towards FDU reform (including pocket change); therefore, a new FDU design strategy should concentrate on improving current FDU functions like mobility (or comfort) rather than dramatic changes. Pilots complained about the quality stability of FDU; therefore, quality control by military administration as well as concrete and clear design instructions by the developer should be attained together. The results obtained in this study are expected to be used as an important basis for the further development of FDU.