• Journal of Yeungnam Medical Science
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• v.8 no.2
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• pp.138-149
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• 1991

This study was aimed at investigation of the stimulatory innervations on the rat urinary bladder. Detrusor muscle strips of 15 mm long were suspended in isolated muscle chambers containing 1 ml of PSS maintained at $37^{\circ}C$ and aerated with 95% $O_2/5%CO_2$. Isometric myography was perfomed, and the results were as followings : Muscle strips showed "on-contraction" by electric field stimulation (EFS) frequency-dependently. The EFS-induced contraction was not affected by hexamethonium, a ganglion blocker, but abolished, by tetrodotoxin, a nerve conduction blocker. Physostigmine, a cholinesterase inhibitor enhanced the EFS-induced contraction which was inhibited by hemicholinium, an inhibitor of choline uptake at the cholinergic nerve ending. Such an EFS-induced contraction was antagonized by atropine only partially, and the atropine-resistant portion was completely abolished by the desensitization of purinergic receptors by prolonged incubatin of the strips in the presence of high concentratin of ATP. Bethanechol, a cholinergic agonist, elicited concentration-dependent contraction. Adenosine triphosphate (ATP), a purinergic agonist, induced a weak but concentration-dependent contraction of short duration. Bethanechol-induced contraction was not affected by ATP-desensitization, and ATP-induced contraction was not affected by tetrodotoxin. These results suggest that there are at least two main stimulatory components of innervations in the detrusor muscle, cholinergic muscarinic and purinergic ; and those receptors are independent each other.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.1
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• pp.259-263
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• 2015

Background: In the field of cancer, the ICD-10 coding convention is based on the site of a neoplasm in the body and usually ignores the morphology, thus the same code may be assigned to tumors of different morphologic types in an organ. Nowadays, all general (provincial) and center hospitals in Thailand are equipped with the hospital information system (HIS) database. Objective: This study aimed to find the characteristics and magnitude of agreement represented by the positive predictive value (PPV) of provisional cancer diagnoses in the HIS database in Pattani Hospital in Thailand in comparison with the final cancer diagnosis of the ICD-10 codes generated from a well established cancer registry in Songklanagarind Hospital, the medical school hospital of Prince of Songkla University. Materials and Methods: Data on cancer patients residing in Pattani province who visited Pattani Hospital from January 2007 to May 2011 were obtained from the HIS database. The ICD-10 codes of the HIS computer database of Pattani Hospital were compared against the ICD-10 codes of the same person recorded in the hospital-based cancer registry of Songklanagarind Hospital. The degree of agreement or positive predictive value (PPV) was calculated for each sex and for both sexes combined. Results: A total of 313 cases (15.9%) could be matched in the two databases. Some 222 cases, 109 males and 113 females, fulfilled the criteria of referral from Pattani to Songklanagarind Hospitals. Of 109 male cancer cases, 76 had the same ICD-10 codes in both hospitals, thus, the PPV was 69.7% (95%CI: 60.2-78.2%). Agreement in 76 out of 113 females gave a PPV of 67.3% (95%CI: 57.8-75.8%). The two percentages were found non-significant with Fisher's exact p-value of 0.773. The PPV for combined cases of both sexes was 68.5% (95%CI: 61.9-74.5%). Conclusions: Changes in final diagnosis in the referral system are common, thus the summary statistics of a hospital without full investigation facilities must be used with care, as the statistics are biased towards simple diseases able to be investigated by available facilities. A systematic feedback of patient information from a tertiary to a referring hospital should be considered to increase the accuracy of statistics and to improve the comprehensive care of cancer patients.

• ALGAE
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• v.20 no.3
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• pp.207-216
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• 2005

Myrionecta rubra, a mixotrophic ciliate, is a cosmopolitan red tide species which is commonly found in neritic and estuarine waters. M. rubra had long been listed as an “nculturable protist”until 2 different laboratory strains were finally established in 2 research groups at the beginning of this century, enabling us to perform initiative investigation into various aspect of the live M. rubra strains (Gustafson et al. 2000; Yih et al. 2004b; Johnson and Stoecker 2005). Field sampling was carried out on high tide at 2 fixed stations around Kunsan Inner Harbor (St.1 near the Estuarine Weir and St.2 off Kunsan Ferry Station) every other day for 4 months from mid-February 2004 to understand detailed figure of the recurrent spring blooms of M. rubra following the onset of the water gates operation of the Keum River Estuarine Weir on August 1994. With its maximum abundance of 272 cells mL$^{-1}$ in St.1, fluctuation pattern of the M. rubra population at the 2 stations was strikingly similar. Notable growth of M. rubra population started on late April, to cause M. rubra red tides during one month from mid-May in which “xceptionally low salinity days”without its red tide were intermittently inserted. High abundance of M. rubra over 50 cells mL$^{-1}$ was recorded at samples with their water temperature and salinity higher than 15${^{\circ}C}$ and 4.0 psu, respectively. During pre-bloom period when salinity fluctuation is moderate and the water temperature is cooler than 15°C, Skeletonema costatum, a chain-forming centric diatom, was most dominant. Cyanobacterial species such as Aphanizomenon flos-aquae and Phormidium sp. replaced other dominant phytoplankters on the days with “xceptionally low salinity”even during the main blooming period of M. rubra. To summarize, M. rubra could form spring blooms in Keum River Estuary when the level of salinity fluctuation was more severe than that for the dominant diatom Skeletonema costatum and milder than that for the predominance by freshwater cyanobacteria. Therefore, optimal control of the scale and frequency of freshwater discharges might lead us to partially modify the fluctuation pattern of M. rubra populations as well as the period of spring blooms by M. rubra in Keum River Estuary. Sampling time interval of 2 days for the present study or daily sampling was concluded to be minimally required for the detailed exploration into the spring blooms by M. rubra populations in estuaries with weirs like Keum River Estuary.

• Journal of Korean Tunnelling and Underground Space Association
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• v.9 no.1
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• pp.37-47
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• 2007

The shield tunneling method has been increasingly employed to minimize environmental damages and civil complaints in the populated and developed area. A lining segment, which is a main structure of the shield tunnel, consists of joints. Conventional foreign and domestic design data have been commonly used for design practices without a specific verification of structural analysis models, design load, and the effect of soil characteristics on the performance of lining segment. In this study, the suitability of existing analytic models used for the design of shield tunnel lining segment has been evaluated through a comparison between analytical and numerical solutions. Based on the evaluation of their suitability performed in the study, a full-circumferential beam jointed spring model (1R-S0) is proposed for design practices by considering user's convenience, the applicability of field conditions and the accuracy of analysis result. By using the proposed model, the parameter analysis was performed to investigate the effects of joint stiffness, ground rigidity, joint distribution and the number of joints on the behavior of lining segment. Parameters considered in the investigation have been appeared to affect the behavior of lining segment. Among those parameters, joint stiffness has been appeared to have the most significant effect on the bending moment and displacement of lining segment.

• Journal of the Korea Organic Resources Recycling Association
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• v.7 no.2
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• pp.35-45
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• 1999

The effect of compost to force the cultivation using various soil and vegetation was investigated 5 times in the field for 4 years. Sewage sludge compost was validated to be useful fertilizer for the growth of a plant. and the optimal amendment amounts of compost to soil depended on the kinds of soil and vegetation, and the organic contents of compost. In the case of compost with high organic content. the optimal amended compost weight was 0.12t/are in fertile-dark brown(eutrophic) soil, 0.2t/are in sandy soil(trophic) and 0.4t/are in infertile-dark brown(oligotrophic) soil, respectively. In the case of compost with low organic content. on the other hand, the amentments of compost up to 0.6t/are was allowable without negative effect on the applied vegetation. Consequently, it can be believed that the sewage sludge compost is useful fertilizer, if keep the optimal amendment amounts(0.4t/are. year) to improve soil on cultivation of vegetation.

• Journal of the Korea Organic Resources Recycling Association
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• v.12 no.2
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• pp.72-81
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• 2004

For disposal food wastes which is about 30% portion of tatal organic wastes, vermicomposting is more environmental-friendly treatment than lanfill, incineration, etc. Recently, the interest has been increasing but there are many problems on management of vermicopmposting in field especially. This study was conducted to investigate an optimal factors, which are limit NaCl conc., the mixing rate of food wastes and casting for growth of an earthworm related to efficient vermicomposting. The limit conc. of NaCl was 0.5% and in case of feeding food wastes to earthworms as a prey only, most earthworms were dead in a few hours due to excessive degradation of organic materials and high NaCl conc. However as feeding with the casting of proper mixing rate(3:7), most earthworms were survived until finishing composting. It was investigated the increaser degree of matureness of food wastes, the higher conc. of NaCl, therefore for efficient vermicomposting, it seemed proper mixing rate of food wastes and the casting is better than matureness of food wastes. and the most suitable mixing rate was 3:7 food wastes and the casting.

• Journal of Korean Society for Atmospheric Environment
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• v.23 no.5
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• pp.547-556
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• 2007

The release, sampling and analytical methods have been developed and tested for perfluorocarbons (PFCs) atmospheric tracers in order to gain insight into the atmospheric transport and dispersion over the urban conditions of Seoul, Korea. Although PFCs tracer experiments provide unique opportunities to test local and urban scale of transport and dispersion, no previous experiment with PFCs has been conducted in Korea. PMCH and PDCH were chosen as targeted tracers in our study due to their extreme low ambient concentrations and great sensitivities among various PFCs. For PFCs release system, a set of micro-metering pump, electronic balance, vaporizing furnace and high speed blower was constructed for precise and accurate release of tracers. The precision of released rate by this system was estimated to be 1%. Samplings of PFCs were carried out by fabricated portable air samplers with micro pumps and rotameters into glass tubes packed with 150 mg of Carboxen-569. The uncertainty of these sampling system was maintained below 14%. PMCH and PDCH were quantified in GC/ECD with preconditioned injection system to eliminate the interference compounds using traps and subsequent catalytic conversion system prior to column separation. Three intensive field test were undertaken during the springtime of 2002 to 2004 in eastern part of Seoul. Daily background samples were collected to characterize the background levels of PMCH and PDCH prior to their release. The observed background concentrations of PMCH ranged from 3.5 to 10.1 fL/L and varied randomly in location and time in this study. Its mean and standard variation of background concentration ($6.8{\pm}1.9\;fL/L$) are higher than those ($3.2{\sim}5.8\;fL/L$) of other historic tracer studies. Identified uncertainty for background PMCH was $1.7{\sim}2.0\;fL/L$ using this analytical system. Combined relative uncertainty in determining the tracer's concentrations was estimated as 17%. However, its background concentrations and uncertainty in concentration determination were found to be low and stable enough for tracer study.

• The Journal of the Acoustical Society of Korea
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• v.37 no.5
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• pp.263-270
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• 2018

In most industry fields concerning external flow noise problems, the hybrid computational aeroacoustic techniques based on the FW-H (Ffowcs Williams and Hawkings) equation are widely used for its numerical efficiency. However, when the surface integral form of FW-H equation is used without volume quadrupole sources, it is known to generate significant non-physical noise in a certain case. Especially, in the case of a flow in which the tip vortex cavitation is formed in the distant downstream direction such as flow driven by an underwater propeller, the accuracy in noise prediction becomes poor unless it is not properly modelled. Therefore, in this study, the nonphysical acoustic waves caused by the surface integral form of FW-H equation is reduced by adding the quadrupole correction term. First, to verify the accuracy of the in-house code of FW-H equation, the noise by an axial fan used in the outdoor unit of air conditioner was calculated and compared with the results of ANSYS Fluent. In order to verify the effects of the quadrupole correction term, the noise prediction for isentropic vortex convection is performed and it is confirmed that the error is reduced by the quadrupole correction term. Finally, the noise prediction is performed for the flow field generated by the Clark-Y hydrofoil in underwater. It is confirmed that the error caused by the cavitation passing through the integral surface can be reduced by the quadrupole correction term.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2002.11a
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• pp.147-153
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• 2002

Due to the growth of population and industrial development at the coastal cities, there has been much increase in necessity to effective control of the wastes into the coastal water and river. The amount of disposal at those waters has been increased rapidly and it is necessary for us to track of it in order to keep the water clean. The investigation and research related to the water quality in this region have been conducted continuously but the systematic survey of the disposed wastes at the bottom was neglected and/or minor. In this study we surveyed the status of disposed waste distribution at the bottom coastal water and river from the scanned images. The intensity of sound received by the side scan sonar tow vehicle from the sea floor provides information as to the general distribution and characteristics of the superficial wastes. The port and starboard side scanned images produced from a transducer borne on a tow fish connected by tow cable to a tug boat have the area with width of 22m∼112m, and band of 44m∼224m. All data are displayed in real-time on a high-resolution color display (1280 ${\times}$ 1024 pixels) together with position information by DGPS. From the field measurement and analysis of the recorded images, we could draw the location and distribution of bottom disposals. Furthermore, we made a database system which might be fundamental for planning the waste reception and process control system.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.363-363
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• 2014

Ruthenium (Ru) has attractive material properties due to its promising characteristics such as a low resistivity ($7.1{\mu}{\Omega}{\cdot}cm$ in the bulk), a high work function of 4.7 eV, and feasibility for the dry etch process. These properties make Ru films appropriate for various applications in the state-of-art semiconductor device technologies. Thus, it has been widely investigated as an electrode for capacitor in the dynamic random access memory (DRAM), a metal gate for metal-oxide semiconductor field effect transistor (MOSFET), and a seed layer for Cu metallization. Due to the continuous shrinkage of microelectronic devices, better deposition processes for Ru thin films are critically required with excellent step coverages in high aspect ratio (AR) structures. In these respects, atomic layer deposition (ALD) is a viable solution for preparing Ru thin films because it enables atomic-scale control of the film thickness with excellent conformality. A recent investigation reported that the nucleation of ALD-Ru film was enhanced considerably by using a zero-valent metallorganic precursor, compared to the utilization of precursors with higher metal valences. In this study, we will present our research results on the synthesis and characterization of novel ruthenium complexes. The ruthenium compounds were easy synthesized by the reaction of ruthenium halide with appropriate organic ligands in protic solvent, and characterized by NMR, elemental analysis and thermogravimetric analysis. The molecular structures of the complexes were studied by single crystal diffraction. ALD of Ru film was demonstrated using the new Ru metallorganic precursor and O2 as the Ru source and reactant, respectively, at the deposition temperatures of $300-350^{\circ}C$. Self-limited reaction behavior was observed as increasing Ru precursor and O2 pulse time, suggesting that newly developed Ru precursor is applicable for ALD process. Detailed discussions on the chemical and structural properties of Ru thin films as well as its growth behavior using new Ru precursor will be also presented.