• Title/Summary/Keyword: favor

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Comparison of Qualified Diagnosis of "Atypical Squamous Cells of Undetermined Significance" with Subsequent Biopsy ("Atypical Squamous Cells of Undetermined Significance"의 질적 분류와 조직 소견과의 비교)

  • Koh, Jae-Soo;Chung, Jin-Haeng;Lee, Seung-Sook;Cho, Kyung-Ja
    • The Korean Journal of Cytopathology
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    • v.10 no.1
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    • pp.1-5
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    • 1999
  • To evaluate whether different qualifications of a cytologic diagnosis of "atypical squamous cells of undetermined significance(ASCUS)" predict a greater or lesser likelihood of tissue diagnosis of uterine cervix, we compared different cytologic qualifications of ASCUS with the tissue diagnosis. One hundred twenty-two consecutive Papanicolaou smears showing ASCUS in women who had undergone cervical biopsy within nearest 30 days were collected. The 122 smears were qualified as "favor reactive"(25%), "favor low grade squamous intraepithelial lesion (LSIL)"(24%), "favor squamous intraepithelial lesion(SIL)"(16%), "favor high grade squamous intraepithelial lesion(HSIL)"(16%), and "not otherwise specified"(19%). Squamous intraepithelial or invasive lesion was pathologically confirmed by cervical biopsy in 13%, of the "favor reactive", 27% in "favor LSIL", 70% in "favor SIL", 75%, in "favor HSIL", and 35% in "not otherwise specified" smears. There were significant associations between the favor reactive smear and the benign biopsy finding and between the favor SIL smear and the biopsy shewing a squamous intraepithelial or more severe lesion. Nevertheless, most of favor LSIL smears exhibit reactive process in tissue biopsy. Conclusively, qualified ASCUS stratifies women Into different risk groups for SIL. The cytopathologist should make the cytologic diagnosis of "ASCUS, favor LSIL" circumspectly.

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Detecting Differential Item Functioning based on Gender: Field of Mathematics in the TIMSS 2007 (초등학생의 성별에 따른 차별기능문항 분석: 수학 과학 성취도 국제비교연구(TIMSS) 2007 수학영역을 중심으로)

  • LEE, Seungbae;KIM, Sukwoo
    • Journal of Fisheries and Marine Sciences Education
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    • v.29 no.3
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    • pp.757-766
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    • 2017
  • This study investigated not only the existence of differently functioned item due to gender but also domain. In this study, the randomly selected data of TIMSS 2007, which consist of 681 male and 646 women, were analyzed. To detect differently functioned items, this study employed Raju method. For Raju method, three-parameter logistic model was selected. Signed and unsigned area between two item characteristic curve were measured within the real ability range. An item which was detected commonly SA and UA area in Raju method was defined as a differently functioned item. As a result of this study, six items among twenty seven items of mathematics in the TIMSS 2007 were differently functioned item. Five items among those six items, were in favor of boys and one item was in favor of girls. Number, Geometric Shapes and Measures, and Applying were in favor of boys. but Data Display, Reasoning were in favor of girls. The conclusion of this study was summarized as existing differently functioned items in TIMSS 2007 and difference between favorable domain based gender. Finally, it is desirable to consider the differently functioned items by relating those item content for improving the test reliability of TIMSS 2007.

Predictive model for wave-induced currents and 3D beach evolution based on FAVOR Method

  • Kuroiwa, Masamitsu;Abualtayef, Mazen;Takada, Tetsushi;Sief, Ahmed Khaled;Matsubara, Yuehi
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.2 no.2
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    • pp.68-74
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    • 2010
  • The development of a numerical model using the fractional area/volume obstacle representation (FAVOR) method for predicting a nearshore current field bounded by complicated geometric shapes, and a three-dimensional (3D) beach evolution was described in this article. The 3D model was first tested against three cases to simulate the nearshore current fields around coastal structures, a river mouth, and a large scale cusp bathymetry. Then, the morphodynamic model tests, which are adopting the nearshore current model, were applied for the computations of beach evolution around a detached breakwater and two groins. It was confirmed that the presented model associated with the FAVOR method was useful to predict the nearshore current field in the vicinity of the complicated geometric shapes. Finally, the model was applied to a tombolo formation in a field site of Kunnui fishery port, which is located in Hokkaido, Japan.

3D-QSARs of Herbicidal 2-N-Phenylisoindolin-1-one Analogues as a New Class of Potent Inhibitors of Protox

  • Soung, Min-Gyu;Lee, Yoon-Jung;Sung, Nack-Do
    • Bulletin of the Korean Chemical Society
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    • v.30 no.3
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    • pp.613-617
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    • 2009
  • 3D-QSARs for the inhibition activities against protox by herbicidal 2-N-phenylisoindolin-1-one derivatives were studied quantitatively using CoMFA and CoMSIA methods. The result of the statistical quality of optimized CoMSIA model 2 ($FF:\;{r^2}_{cv.};\;0.973\;&\;{r^2}_{ncv.};\;0.612$) was higher than that of CoMFA model 1 ($AF:\;{r^2}_{cv.};\;0.414\;&\;{r^2}_{ncv.};\;0.909$). Also, the relative contribution of the optimized CoMSIA model 2 showed the steric (24.6%), electrostatic (31.0%), hydrophobic (ClogP, 23.4%) and H-bond acceptor field (21.0%), respectively. From the results of the contour maps, the protox inhibition activities are expected to increase when steric favor and H-bond acceptor favor groups are substituted on $R_2$ position and positive favor group are substituted on $C_2,\;C_3,\;and\;C_5$ atom in phenyl ring of $R_2$ position. And the inhibition activities are expected to increase when hydrophobic favor group is substituted on $C_1,\;C_3$ atom in phenyl ring of $R_2$ position and $C_1$ atom of $R_2$ position and hydrophilic favor groups are substituted on $C_4$ atom in phenyl ring of $R_1$ position and the terminal group of $R_1$ position.

Men's Cosmetics Purchasing Behavior Based on the Level of Interest in Appearance, the Country of Origin, and the Sales Promotion (외모관심도, 화장품 브랜드원산지 및 판촉유형에 따른 남성화장품 구매행동)

  • Jang, Jin-Young;Hwang, Sun-Jin;Jeon, Ho-Kyung
    • Journal of the Korean Society of Costume
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    • v.57 no.6 s.115
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    • pp.160-171
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    • 2007
  • This research studied men's cosmetics purchasing behavior based on the level of interest one has in one's appearance, the country of origin, and the sales promotion of the cosmetics. The study was conducted by experimental $2{\times}[2{\times}2]$ design by combining the 3 variables mentioned above. The Independent variables in this research were levels of appearance interest(high vs. low), the country of origin(Korean vs. foreign), and types of sales promotion(discount vs. coupon). The dependent variables were the purchase behaviors including favor to cosmetics and purchase intent. Two hundred male consumers participated for the study. Data analysis conducted were factor analysis, cluster analysis and ANOVA. The results were as follows. 1. Male consumers' cosmetics favorness: 3-way significant interaction, in appearance interest, the country of origin, and types of sales promotion, was found for favor to male cosmetics. When male subjects were provided with price discounts and skin care coupons for the Korean cosmetics, they didn't reveal significant differences in favor, regardless of the level of appearance interest. However, for the imported cosmetics, male subjects with high appearance interest showed more favor to the cosmetics than the ones with low appearance interest. 2. Male consumers' purchase intent: 3-way significant interaction, in appearance interest, the country of origin, and types of sales promotion was found for the purchase intent. When male subjects were provided with price discounts and skin care coupons for the Korean cosmetics, they didn't show significant difference in purchase intent, regardless of their appearance interest. However, for the imported cosmetics, male consumers with high appearance interest reported more purchase intent than the ones with low appearance interest.

PhotoToc: an Implementation of a Ranking System by using User Favor-Based Metrics (포토톡 : 사용자 선호 기반 멀티미디어 콘텐츠 랭킹 시스템의 구현)

  • Lee, Jin-Soo;Park, Al-Eum;Choi, Song-Ah;Ahn, Hoo-Young;Park, Young-Ho
    • Journal of Digital Contents Society
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    • v.8 no.2
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    • pp.113-119
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    • 2007
  • Recently, multimedia applications using internet are increasing by emergency of UCC. The retrieval of photo, video, audio is a main issue to increase utility of access and efficiency of access time. But the exist multimedia applications do not provide the practical ranking system. They provide only simple ranking system using metric. This paper provides "PhotoToc", the user favor-based multimedia ranking system, that can provide differenced view to users. The proposed system has a to retrieve the user centered results.

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CoMFA and CoMSIA on the Inhibition of Calcineurin-NFAT Signaling by Blocking Protein-Protein Interaction with N-(4-Oxo-1(4H)-naphthalenylidene)benzenesulfonamide Derivatives

  • Myung, Pyung-Keun;Park, Kyung-Yong;Sung, Nack-Do
    • Bulletin of the Korean Chemical Society
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    • v.26 no.12
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    • pp.1941-1945
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    • 2005
  • To raises the possibility of designing effective inhibitors, 3D-QSAR for the inhibition of calcineurin-NFAT signaling by new N-(4-oxo-1(4H)-naphthalenylidene benzenesulfonamide derivatives as inhibitors of intracellular protein-protein interactions were studied using CoMFA and CoMSIA methodology. The three templates, N-(4-oxo-1(4H)-naphthalenylidene)benzenesulfonamide (A), benzenesulfonamide (B) and 4-oxo-1(4H)-naphthalenylidene (C) were selected to improve the statistic of the present 3D-QSAR models. The best models with combination of standard field in CoMFA, and steric field and electrostatic field in CoMSIA derived from the template, B and C, because most of the compounds tend not to be aligned in template A. From the based on the CoMFA and CoMSIA contour maps, the $R_1$ and $R_2$ groups on 4-oxo-1(4H) naphthalenylidene ring are steric favor. The ortho position on the benzenesulfonyl ring is steric disfavor and the meta position is steric favor. In addition, the oxygene atom of carbonyl group will have better inhibition activities as it has a negative charge favor. From these findings, we can conclude that the analyses of the contour maps provided insight into possible modification of molecules for effective inhibitiors.

The Effects of Conspicuous Consumption, Sales Promotions and Images of the Country of Manufacture on Chinese Women Consumers' Purchasing Attitudes to Fashion Luxury Brands (과시소비성향, 판매촉진과 제조국 이미지가 중국여성소비자의 패션 명품 구매태도에 미치는 영향)

  • Yin, Shu;Hwang, Sun-Jin;Byun, Yoo-Sun
    • Journal of the Korean Society of Costume
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    • v.62 no.1
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    • pp.49-61
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    • 2012
  • The purposes of this study were study intended to investigate effects of conspicuous consumption, sales promotions and images of the country of manufacture on Chinese consumers' purchasing attitudes to fashion luxury brands. The study was conducted by experimental conspicuous consumption(2)X[types of sales promotions(2) X images of the country of manufacture(2)] design by combining the 3 variables mentioned above. 312 women living in Chengdu were collected for this study. For data analysis, factor analysis, T-test, frequency analysis and ANOVA were used. The results were as follows: First, Chinese consumers' favor to fashion luxury brands: 2-way interactions, in sales promotions and images of the country of manufacture, was found for favor to fashion luxury brands. Second, Chinese consumers' purchase intent to fashion luxury brands: only the main-effects of conspicuous consumption and images of the country of manufacture was meaningfully positive. It demonstrates that only conspicuous consumption and images of the country of manufacture effected Chinese consumers' purchase intent to fashion luxury brands.

Structural Characteristics that Influence on the Insecticidal Activity of 2-(n-Octyl)pseudothiourea Analogues against the Diamondback Moth (Plutella xylostella, L.)

  • Soung, Min-Gyu;Kil, Mun-Jae;Sung, Nack-Do
    • Bulletin of the Korean Chemical Society
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    • v.30 no.11
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    • pp.2749-2753
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    • 2009
  • Structural characteristics that influence on the insecticidal activity ($pI_{50}$) of 2-(n-octyl)isothiourea analogues (1-45) against the diamondback moth (Plutella xylostella, L.) based on three dimensional quantitative structure activity relationships (3D-QSARs) were discussed quantitatively using a comparative molecular field analysis (CoMFA) and a comparative molecular similarity indeces analysis (CoMSIA) methods. The statistical values of the CoMFA 2 model were better than those of the CoMSIA 1 model. The CoMFA 2 model was the optimized model with the correlativity (the training set: Ave. = 0.104 & PRESS = 0.613) and the predictability (the test set: Ave. = 0.086 & PRESS = 0.096). Insecticidal activities with the optimized CoMFA 2 model were dependent upon steric factors (79.4%) of $R_1-R_3$ substituents. From the analytical results of CoMFA contour maps, it is predicted that the R1 substituent of 1-45 which has a steric favor in a broad space, $R_2\;and\;R_3$ groups with a steric favor in a narrow space and a H-bond donor favor would have better the insecticidal activity.