• Biomedical Science Letters
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• v.10 no.4
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• pp.515-521
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• 2004

To measure regional cerebral blood volume (rCBV) with perfusion MR imaging of cerebral fat embolism by neutral fat and free fatty acids in cats. Triolein (group 1, n=15), oleic acid (group 2, n=9) and linoleic acid (group 3, n=11) were infused into unilateral internal carotid artery using microcatheter through the transfemoral approach. PVA particle was used as a non-fat embolic material in a control group (group 4, n=9). Perfusion-weighted MR image was obtained at 30 minutes and 2 hours postembolization, based on T2-and diffusion-weighted images. The data of lesion and contralateral normal area were transferred to personal computer, time-to-signal intensity curve was drawn and trans for used to △R2/sup */ curve in regular order. The process in the personal computer was done by using the author's developmental image processing program and interactive data language (IDL) softwares. Statistical significance was approved by paired t-test and ANOVA. rCBV of the lesion was decreased comparing to the normal area in all groups. The ratios of rCBV were as follows (group No, at 30 minutes, at 2 hours); group 1,32％, 51％; group 2, 30％, 44％; group 3, 39％, 61％; group 4, 21％, 36％. rCBVs of 2 hours was significantly increased compared to those of 30 minutes in all groups (P<0.005). rCBV was decreased at 30 minutes in cerebral fat embolism and recovered a little, but significantly at 2 hours. Perfusion-weighted images was useful method in offering hemodynamic information in cerebral fat embolism.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3881-3885
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• 2015

Obesity markedly increases the risk of colorectal cancer. Recently, the preventive effects of edible mushrooms on triglyceride elevation and visceral fat accumulation have been reported. Here, the effects of Pleurotus eryngii (Eringi) and Hypsizygus marmoreus (Bunashimeji) on azoxymethane (AOM)-induced aberrant crypt foci (ACF; precancerous lesions) in the colorectums of mice fed a high-fat diet were examined. Eringi (ER) and Bunashimeji (BU) mushroom powder samples were used. Six-week-old male C57BL/6J mice received an intraperitoneal injection of AOM (10 mg/kg) once a week for two weeks, and were sacrificed and dissected at 6 weeks after the start of the experiment. After the initiation of the experiment, they received a normal diet (ND), high-fat diet (HFD), HFD + ER (1 or 5% of diet), or HFD + BU (1 or 5% of diet). As a result, body and fat weights were significantly lower in the 5% ER and BU groups than in the HFD group. Liver triglyceride levels were also significantly lower in the 5% ER and BU groups. Total liver cholesterol levels were significantly lower in the 5% ER group. The numbers of ACF (especially large ACF) showed strong inhibitory effects in both ER and BU groups. Measurement of the cell proliferation marker Ki-67 labeling index in the colonic mucosa demonstrated more significant suppression in both ER and BU groups than in the HFD group. These results suggest that the simultaneous intake of ER and BU may inhibit colorectal tumorigenesis in HFD-fed mice.

• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.6
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• pp.348-355
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• 2017

Aster yomena (AY) have been used as a traditional medicine to treat cough, bronchial asthma, and insect bites in Korea. In this study, we evaluated the inhibition of adipogenesis in 3T3-L1 cells and in high-fat diet (HFD)-induced obese mice by AY ethanol extract. Lipid accumulation measurement indicates that AY markedly inhibited adipogenesis in a dose-dependent manner. qRT-PCR results demonstrated that the mRNA expression of adipogenic transcription factors such as peroxisome proliferator-activated receptor-${\gamma}$ ($PPAR-{\gamma}$) in 3T3-L1 cells were significantly down-regulated by AY treatment. And inhibited the expression of FAS, a protein responsible for lipid synthesis, transport and storage. Oral administration of AY (100, 250, and 500 mg/kg, P.O/daily for 4 weeks) was conducted in high-fat diet induced obese mice and C57BL/6 mice. AY was orally administered for 4 weeks to extract liver and epididymal fat, and hematoxylin and eosin staining(H&E staining) was observed. Observation showed that the fat concentration of liver tissue tended to decrease dose-dependently and decreased significantly at 500 mg/kg concentration. The AY-administered group of HFD-induced mice had a lower body weight gain, along with decreased triglycerides and total cholesterol compared with the control mice, however, the HDL-cholesterol/total cholesterol ratio was increased. These results indicate that AY exhibits anti-obesity effects in obese mice by decreasing in serum lipid levels and lipogenesis related gene.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.3
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• pp.418-424
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• 2006

This experiment was conducted to explore the efficacy of lacquer (Rhus verniciflua) supplementation on growth performance, nutrient digestibility, carcass traits and serum biochemical values in commercial broilers. Eight hundred and forty Hubbard broiler chicks (1d old) were randomly distributed and allotted to four dietary treatments for five weeks. Each treatment had 5 replicates with 42 birds each. The dietary treatments were (1) control (2) 1% lacquer, (3) 2% lacquer and 4) 4% lacquer supplied as meal in the diet. Supplementation with lacquer improved weight gain (p = 0.0960) showing a linear trend during the starter phase (0-3 wk), but weight gain, feed intake and feed conversion ratio remained unaffected at the finisher phase (4-5 wk) and overall (0-5 wk). The nutrient digestibility studies conducted after 18 and 35 days of experimental feeding showed a linear (p<0.05) increase in digestibility of CP and ether extract at both measurement timess. The carcass studies were conducted on two birds per replicate (10 per treatment) at the end of both 3 and 5 wk. The dressing percentage, liver weight, heart weight, abdominal fat and the breast meat expressed as a percentage of live weight, did not differ significantly due to treatments at both phases. The serum cholesterol and high-density lipoprotein (HDL) showed a linear decrease (p = 0.0683 and p = 0.0322, respectively) as the level of supplementation increased at 3 wk; at 5 wk serum cholesterol, HDL and triglyceride levels decreased significantly showing a positive linear effect of lacquer on fat metabolism. The meat color values such as lightness, redness and yellowness did not reveal any significant trend. Overall, it could be concluded that lacquer supplementation at higher levels did not affect growth performance, but had a positive impact on fat metabolism by influencing fat digestibility and reducing serum cholesterol and triglyceride.

• Journal of the Korean Data and Information Science Society
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• v.22 no.2
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• pp.287-296
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• 2011

Thirty six female students participated in the experiment of the fat mass weight loss. they kept diary for foods they ate every day, took a picture of the foods, transmitted the picture to the experimenter by the camera phone, and consulted him about fat mass loss once a week for 8 weeks period. Fat mass weight and its related factors of the students had been measured repeatedly every week during 8 weeks, The repeated measurement data were used for applying various random coefficient models. And hence optimal random coefficient model was selected. From the optimal model, the baseline, body mass index, diastolic blood pressure, total cholesterol and time of the fixed factors were very significant. The fixed quadratic time effect existed. The variance components corresponding to the subject effect, linear time effect of the random coefficients were all positive. Thus random coefficients up to the linear terms were considered as the optimal model. The treatment effect reduced the weight loss to an average of 2.1kg at the end of the period.

• Korean Journal of Community Nutrition
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• v.4 no.1
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• pp.11-19
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• 1999

The purpose of this study was to evaluate the effect of a nutrition education program on 42 obese young adolescent girls. Nutrition education was performed for six months including both group and individual programs, and was focused on improving their eating habits and food composition. The topics discussed once a week included : eating habits, lifestyle management, 5 basic food groups, snack and fast-food, how to eliminate empty calories, fat and hyperlipidemia, food diary, benefits and methods of exercise, vitamin and minerals, evaluation of fad diets, yo-yo effects and so on. The effects of the nutrition education program were evaluated for nutrition education and exercise regimen group (NE＋E), nutrition education only group(NE), and control group(C). NE＋E group had additional exercise programs 3times each week, while NE group was educated about exercise only by a nutrition education program. In both NE＋E and NE groups, there was a significant decrease in bodyfat compared to C group, but NE＋E group had a greater change than NE group(5.5% vs 3.1%). In addition, serum triglycerides decreased about 40mg/dl and total cholesterol 20mg/dl in both NE＋E and NE groups. But HDL-C level was increased only in NE＋E group. The greater changes in body fat and blood lipid levels occurred between the pre- and mid terms fo the education regimen. They kept their changed measurement throughout the 6 months follow-up studies. The results of this study show that this nutrition education program is helpful for obese adolescent girls in decreasing body fat and serum lipid levels. Also, the combination of an exercise regimen with the nutrition education proved to be more effective.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.2
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• pp.125-135
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• 2019

PURPOSE: This study examined the effects of low frequency neuromuscular electrical stimulation (NMES) training on abdominal obesity in middle-aged women through electromyography and ultrasound. METHODS: Twenty-two middle aged women with abdominal obesity participated in the study. A low-frequency NMES device was used on the abdomen and waist of each subject for 20 minutes each (a total of 40 minutes) three times a week for eight weeks. The waist-hip ratio (WHR), weight and BMI (Body Mass Index) were measured. Electromyography (EMG) and ultrasound measurements were performed three times in total (pre-intervention, four weeks into the intervention, and eight weeks post-intervention) to examine the effects of low-frequency NMES on the abdominal muscle activity, muscle thickness, and subcutaneous fat. RESULTS: The results indicated a difference in the WHR and waist circumference before and after intervention (p<.05). The external oblique muscle (EO) showed a significant increase in muscle activity during all measurements taken post-intervention (p<.05). The abdominal subcutaneous fat thickness also showed a significant decrease between each measurement (p<.05). The test results showed that the abdominal subcutaneous fat thickness values taken eight weeks post-intervention were significantly lower than those taken pre-intervention and four weeks into the intervention (p<.05). CONCLUSION: These findings show that low-frequency NMES device training can be applied to middle-aged women with abdominal obesity to improve their body shape and exercise performance.

• Journal of Cardiovascular Imaging
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• v.31 no.4
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• pp.169-177
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• 2023

BACKGROUND: Acute worsening of cardiac function frequently leads to kidney dysfunction. This study aimed to identify clinical and imaging parameters associated with impaired kidney function in patients with acute decompensated heart failure with reduced ejection fraction (HFrEF). METHODS: Data from 131 patients hospitalized with acute decompensated HFrEF (left ventricular ejection fraction, < 40%) were analyzed. Patients were divided into two groups according to the glomerular filtration rate (GFR) at admission (those with preserved kidney function [GFR ≥ 60 mL/min/1.73 m²] and those with reduced kidney function [GFR < 60 mL/min/1.73 m²]). Various echocardiographic parameters and perirenal fat thicknesses were assessed by computed tomography. RESULTS: There were 71 patients with preserved kidney function and 60 patients with reduced kidney function. Increased age (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.04-1.12; p = 0.005), increased log N-terminal pro b-type natriuretic peptide (OR, 1.74; 95% CI, 1.14-2.66; p = 0.010), and increased perirenal fat thickness (OR, 1.19; 95% CI, 1.10-1.29; p < 0.001) were independently associated with reduced kidney function, even after adjusting for variable clinical and echocardiographic parameters. The optimal average perirenal fat thickness cut-off value of > 12 mm had a sensitivity of 55% and specificity of 83% for kidney dysfunction prediction. CONCLUSIONS: Thick perirenal fat was independently associated with impaired kidney function in patients hospitalized for acute decompensated HFrEF. Measurement of perirenal fat thickness may be a promising imaging marker for the detection of HFrEF patients who are more susceptible to kidney dysfunction.

• Journal of the Korean Home Economics Association
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• v.37 no.2
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• pp.113-126
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• 1999

In order to investigate the detergency effect of stained cotton and PET fabric, respectively, these fabrics stained with solid soils such as carbon black, liquid paraffin, and fat and examined the detergency effect in the optimum washing condition. The evaluation of washing efficiency of washed fabrics studied by using the surface reflectance measurement before and after washing treatment. The maximum detergency effect of stained cotton and PET fabric obtained in the mixed washing liquor-bleachig agen(ml)/concentrated washig agent(g/l). To obtain the excellent detergency effect, 2-step washing treatment, pre-washing by bleaching agent only and washing by concentrated detergent, is preferred. In comparing the detergency of polyester and cotton fabric, the detergency of stained polyester fabric superior than that of stained cotton fabric because of the difference of adhesive force between soil material and fabric in preparing soled stained fabric. In this study, we also studied the degree of fabric damage by the measurement of tensile strength change. From the results of the tensile strength measurement, the damage of washed fabric before and after washing treatment was nearly changed.

• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.456-457
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• 2003

The use of relaxing cosmetic products is more and more widespread on the self care market, since stress is considered as a major cause of discomfort in modem life. Cortisol, the stress hormone, helps the human body to regulate itself by acting on carbonhydrate, proteins and fat metabolisms. IgA are immune molecules involved in the stress response of the human body. The less the human body is stressed, the more the salivary IgA rate increases. Salivary cortisol and IgA have the advantage of being easily assessed with non invasive methods. Finally, conductance is the measurement of the modification in the electrical resistance of the skin. By this means, the measurement of the conductance enable the assessment of somebody's stress.(omitted)