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Effects of Electroacupuncture on the Modulation of Formalin-induced Pain in the Rat (흰쥐 족저에 Formalin 주입으로 유발된 통증반응에 대한 전침 효과)

  • 김재효;최동옥;김민선;박병림;손인철
    • The Journal of Korean Medicine
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    • v.23 no.2
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    • pp.97-107
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    • 2002
  • Objective : Acupuncture is a method used to treat many kinds of pain in oriental cultural medicine. Especially when hetero-segmental area acu-points are stimulated, the therapeutic effects of pain control have more critical properties than other methods of acupuncture. However, the mechanism of pain control by acupuncture is contradictory so far. The present study examined the effects of electroacupuncture (EA) applied to the acu-point of the hetero-segmental area on modulation of formalin-induced pain in Sprague-Dawley rats. Methods : In order to apply EA to acu-points in the plantar area of right forepaws, a pair of Teflon-coated stainless steel wires were implanted in HT 7 (Shin-Moon) and PC 7 (Dae-Reung) 7 days before the behavioral test. A behavioral test was performed by means of video camera after injection of 5% formalin ($50{\;}\mu\textrm{l}$) into the lateral plantar region of the left hind paw. EA was delivered by a constant DC current stimulator at 4~5 mA, 2 ms, and 10 Hz for 30 min. c-Fos protein expression was measured in the lumbar spinal cord at 2 hr and 4 hr after formalin injection. Results : Behavioral responses including favoring, flinching and biting occurred in the biphasic pattern, such as the 1st phase (0~5 min) and the 2nd phase (20~45 min) after formalin injection. However, EA (4~5 mA, 2 ms, 10 Hz) significantly inhibited the behavioral responses. Injection of formalin expressed c-Fos protein on the ipsilateral dorsal horn neurons in L3 - L5 and the expression was sustained more than 4 hrs after formalin injection. However, EA decreased c-Fos protein expression at dorsal horn neurons in the lumbar spinal cord till 4hrs after formalin injection. Conclusions : These results suggest that EA modulates formalin-induced pain and this inhibitory action may be elicited by the descending inhibitory system.

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A Study on the Consequences of Dissolution Intention (관계해지의도의 결과변수에 관한 연구)

  • Kang, Bo-Hyeon;Oh, Se-Jo
    • Proceedings of the Korean DIstribution Association Conference
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    • 2005.05a
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    • pp.87-110
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    • 2005
  • So far, the studies on the dissolution of relationship have regarded dissolution intention as the final consequence, therefore have not investigated phenomena after the formation of dissolution intention. This study is a seminal work which shows the mechanisms of deterioration of dissolution intention toward complete dissolution. So, this study has the scope from the formation of dissolution intention and to the right before of the complete dissolution. This study has investigated the consequences of dissolution intention(increasing opportunism, decreasing transaction specific investment, and decreasing cooperation) and the relationships of them empirically. As the result of hypotheses test using data collected from 179 newspaper branch office samples, all hypotheses are supported. Dissolution intention has the positive effect on opportunism and negative effect on transaction specific investment. Opportunism decrease transaction specific investment and cooperation. And, transaction specific investment has the positive effect on cooperation. Finally, the authors discussed the theoretical contributions, managerial implications, and limitations of this study and presented the future research directions.

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Various Issues on International Guarantee (국제적(國際的) 보증(保證)의 제문제(諸問題))

  • Suk, Kwang-Hyun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.17
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    • pp.7-35
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    • 2002
  • In many international financing transactions Korean companies are required to issue a guarantee. Thus far, however, legal issues on international guarantees have not been fully discussed in Korea. This is partly because most of the international guarantees are governed by a foreign law such as English law or the laws of the State of New York. In this articles the author examines major concepts or terms and conditions of a typical international guarantee, e.g., language on consideration, primary obligor, joint and several guarantee, unconditional and irrevocable guarantee, continuing guarantee, right of subrogation, representations and warranties, covenant or undertaking, currency indemnity, assignment, participation, governing law and jurisdiction clause, etc. For reference, standard forms of a guarantee and a standby letter of credit are attached to the article. In examining the terms and conditions, the author compares them with similar or equivalent concepts under Korean law. The author further discusses some Korean law issues that may arise under international guarantees governed by a foreign law. These issues include the application of the ultra vires doctrine under Article 34 of the Civil Code of Korea, the validity of an international guarantee which a Korean company has issued in violation of the guarantee ceiling set under Article 10 of the Law on Monopoly Regulation and Fair Trade of Korea and the validity of an international guarantee which a Korean party has issued in violation of the Foreign Exchange Transaction Law. In addition, the author discusses some issues under a so-called independent guarantee and a standby letter of credit. In this regard, reference is made to the Uniform Rules for Demand Guarantee (URDG), International Standby Practices (ISP98) and the Convention on Independent Guarantees and Stand-by Letters of Credit adopted by the United Nations in 1995. Finally, the author examines major terms and conditions of typical comfort letters and discusses some legal issues, such as the binding force of the comfort letter. In dealing with the issues the author underscores that to the extent the issues are not properly dealt with by an international norm such as Uniform Customs and Practice for Documentary Credits or ISP 98, the issues must be analyzed by reference to the governing law of the relevant instrument.

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A Study on Bulgarian Folk Costume - Focusing on Woman's Costume - (불가리아 민족복식의 고찰 - 여성복을 중심으로 -)

  • Rha, Soo-Im
    • Journal of the Korea Fashion and Costume Design Association
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    • v.11 no.1
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    • pp.53-62
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    • 2009
  • Through the result of the investigation on costumes in Bulgarian regions, the main factors for the formation of Bulgarian folk costume and its kinds and history have been found out so far as follows. Alhtough varying according to the district and climate, Bulgarian folk costumes have some general features determined by the material, the pattern, the application. For women, Bulgarian costume consists of a white shirt, a single or double apron unique depending on each region(Bruchnick), a basic dress called a tunic (Soukman), and an open-tunic typed coat (saya). The main factors for the formation of Bulgarian folk costume have been under the influence of natural and environmental features and historical streams resulting from its geographical location. Bulgaria is agriculture-oriented society based on a continental climate. Accordingly, as for the classification of costumes, body-fit clothes, such as shirts and jackets which developed in Europe and fit the body shape, have featured in Bulgaria. Besides, Bulgaria was under the rule of Turk for a long time at the end of the Middle Age. Having been influenced a lot those days, its folk costume shows Turkish elements now. With geographical features, it was found that the southern area was influenced most by Turkey and Greece, and the types of folk costumes in Europe developed mainly from the northern area. The adaptation of traditional costume forms to the new cultural and progressive principles of appeal nowadays needs knowledge, as well as feeling. Finding the right measure and proportions of using old ethnic elemints in contemporary clothing is the prerequisite of successful design.

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Postural Control During Virtual Moving Surround Stimulation in Patients with Brain Injury (뇌기능 장애 환자의 가상 환경 움직임(Virtual Moving Surround) 자극에 따른 자세 균형 제어)

  • 김연희;최종덕;이성범;김종윤;이석준;박찬희;김남균
    • Science of Emotion and Sensibility
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    • v.5 no.4
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    • pp.67-75
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    • 2002
  • The purpose of this study is to assess the ability of balance control in virtual moving surround stimulation using head mount display (HMD) device and force platform in patients with brain injury. Fifteen patients with stroke (mean age 54.47 yrs) and fifteen healthy normal persons participated. COP parameters were obtained total path distance, frequency of anterior-posterior and medial-lateral component by FFT analysis, weight-spectrum analysis in the two different conditions; (1) during comfortable standing with opened or closed eyes, (2) during virtual moving surround stimulation delivered using HMD with four different moving pattern. Moving patterns consisted of close-far, superior-inferior lilting (pitch) , right-left tilting (roll) and horizontal rotation (yaw) movement. In all parameters, the test-retest reliability was high. Also, the construct validity of virtual moving surround stimulation was excellent (p<0.05). A posturographic balance assessment system equiped with virtual moving surround stimulation using HMD is considered clinically useful in evaluation of balance control in patients with brain injury.

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A Study on the changes the electronic game by the times (전자게임의 시대별 변천과정에 관한 연구)

  • 은광하;이동연
    • Archives of design research
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    • v.15 no.1
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    • pp.327-338
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    • 2002
  • Nowadays, in accordance with our information-oriented society, industries based on digital Technology have been quickly developing all over the world. This industryhas been playing an important role in improving the quality of peoples'lives so far and will continue to do so, both culturally and socially through industrial and economic aspects. Particularly, the electronic game, on e of the representatives, is providing an intensive value-added segment to the entertainment industry. Games are deeply rooted in people's lives and have a big influence on the industry, society and culture, even our life styles. Consequently, this study is investigating change the electronic game by the times and analyzing the game entity. It is based on the research and analysis of the transition of electronic games in each era. From now on, we will look forward, using previous material in an attempt to forecast the right direction of electronic game design in the future.

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Factors Affecting Spatial Distance to Outpatient Health Services (공간분석을 이용한 외래의료서비스 접근성 요인분석)

  • Shin, Ho-Sung;Lee, Sue-Hyung
    • Health Policy and Management
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    • v.21 no.1
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    • pp.23-43
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    • 2011
  • Access to health care is complicated to define. It is a multidimensional process. In addition to the matters of quality of care, geographical accessibility and availability of the right type of care, finance, and acceptability are all involved. The purposes of this paper are to measure the geographic distances between patient residency locations and health service organizations in which the patients hadvisited, and to investigate the association between geographical distance measures and variables involved in health service utilization. The study used the first and the second wave of the 2008 Korea Health Panel Survey. The samples of analyses were patients who had visited outpatient or used ambulatory health services, and the total observations (visit numbers) analyzed were 229,128. We divided the samples into a frequent-visit illness group (Group 1) and a non-frequent visit illness group (Group 2) based on over 5,000 total visit numbers. We exploited three level analyses using xtmixed of STATA${\Box}$ 11.1 command with/without interaction terms among age, sex, and occupation. Geographical distances were measured using the Haversine method. Group 1 was tended to older and lower equivalent income than those of Group 2, but the geographic difference were not observed in terms of area deprivation index and standard mortality ratios. Amongst group 1, diabetes mellitus patients travelled far to visit health care organizations, and arthritis patients were more deprived in terms of the personal and areal characteristics. The study revealed that residents in rural areas traveled about 10 times more long distances than those whom lived in larger cities after adjusting for various variables, which we used for analyses. This study contributed to the practical understanding of health service utilizations using empirical analyses, and found that the types of diseases and socioeconomic characteristics of patients tended to define the amount of travel distance to healthcare organizations.

The studies on the Chang-Pu and physiological theories of "NanJing hoeju jeonjung" ("난경회주전정(難經滙注箋正)"중(中) 장부생리(臟腑生理)에 대한 연구(硏究))

  • Je, Kang-Woo;Yoon, Chang-Yeu
    • Journal of Haehwa Medicine
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    • v.15 no.2
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    • pp.75-93
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    • 2006
  • Chang San-roe re-explained the contents from the 30th question to the 47th question of "Nan Jing" which refered to the Chang-Pu and physiological theories as follows through the western theory which wss different from the tranditioonal chinese theory 1. "Nan Jing" refered to the circulation and the coming into being of Yeong-Wi. He denied that it was classified Yeong from Wi or Eum from Yang. 2. He denied that Sam-Cho was separated to three parts and the theory of "Sam-Cho is name only, not shape", using western medical theory. 3. He denied the view about "Left side is kidney, right side is Myung-Mun" because it was incorrect that kidney was separated to two parts which were Su and Hwa or Eum and Yang 4. Re-explaining the contents of "Nan Jing"- the portions of heart and lungs, the rising and falling of liver and lungs, the relationships of five viscera and sound color smell taste fluid, the relationships of five viscera and nine hole, the relationships of five viscera and O-Chu, the physiological difference of the old and the young owing to the deflection of Yeong-Wi Chi-Heol- he thought that viewing the human body using theory of Eum and Yang, Five elements(五行) was a far-fetched interpretation, so he denied the tranditional chinese theory which understood human body's organs, physiology, pathology. 5. He explained the contents of "Nan Jing"- the portions of the colon and the small intestines, the funtion of the six bowls, the corespondence of Chang-Pu, physical peculiarity of liver, the anatomical aspects which were the sizes, weights, volumes and shapes of the Chang-Pu and the alimentary canal, Chil-Chung-Mun, Pal-Hoe-Hyeolthrough western anatomy and physiology in detail.

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An Experimental Study on the Analysis of the Interventricular Pressure Waveform in the Moving-Actuator type Total Artificial Heart (이동작동기식 완전 이식형 인공 심장의 심실간 공간 압력 파형 해석에 관한 실험적 연구)

  • 조영호;최원우
    • Journal of Biomedical Engineering Research
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    • v.18 no.1
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    • pp.25-36
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    • 1997
  • To regulate cardiac output of the Total Artificial Heart(TAH) physiologically, the hemodynamic information must be toed back to the controller. So far, our group has developed an automatic cardiac output control algorithm using the motor current waveform, It is, however difficult to detect the preload level such as a filling status of ventricular inflow and the variation of atrial pressures within normal physiologic range(0-15 mmHg) by analyzing the motor current which simultaneously reflects the afterload effect. On the other hin4 the interventricular volume pressure(IVP) which is not influenced by arterload but by preload is a good information source for the estimation of preload states. In order to find the relationship between preload and IVP waveform, we set up the artificial heart system on the Donovan type mock circulatory system and measured the IVP waveform, right and left atrial pressures, inflow and outflow waveforms and the signals represented the information of moving actuator's position. We shows the feasibility of estimating the hemodynamic changes of inflow by using IVP waveform. fife found that the negative peak value of IVP waveform is linearly related to atrial pressures. And we also found that we could use the time to reach the negative peak in IVP waveform, the time to open outflow valve, the area enclosed IVP waveform as unfu parameters to estimate blood filling volume of diastole ventricle. The suggested method has advantages of avoiding thrombogenesis, bacterial niche formation and increasing longterm reliability of sensor by avoiding direct contact to blood.

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The Analysis of Understanding of the Uevelopment of Fishing Villages and Fishing Ports in Busan (부산시 어촌·어항개발에 대한 의식 분석)

  • KIM, Dae-Sik;LEE, Chun-Woo
    • Journal of Fisheries and Marine Sciences Education
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    • v.17 no.2
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    • pp.218-227
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    • 2005
  • Ocean resources have a very important role to meet the requirements of the people's leisure activities in a limited country, so fishing villages and fishing ports are getting more and more important as a source of supply to satisfy the demands as time goes on. There are various and far-reaching approaches to the fishing villages and fishing ports. However, studies to present the over-all direction of development policy for fishing villages and fishing ports have been short; especially the studies which have been dealing with Busan were verified to be very short relatively. As a result of survey, both officials in charge and residents in fishing villages have an enough understanding of what problems the development of fishing villages have and it's direction of development and spreading effects. In the part of the policy of developing fishing ports, officials answered that insufficient synthetic estimation was main problem in developing the fishing ports, while residents had a high recognition that local fishing ports and small scale fishing ports have had poor progress relatively. In the analysis of difference between two group about the spreading effects of developing fishing villages and fishing ports, they had affirmative opinions rather than negative ones without exemption. As mentioned above, it is a right direction to develop the existing fishing ports as well as new fishing ones to the multi-functional synthetic fishing ports. The specialized development should be made so that the special quality of coastal resources, which fishing villages have, will be made the best use of.