• (The)Study of the Eastern Classic
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• no.33
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• pp.131-158
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• 2008

While there were separation, confrontation and conflicts in Yungnam confucian group in seventeenth century, Nampa Jang Hak(1614~1669), was one of the representative figure among Yeoheon's pupils in doing the project of Yeoheon's enshrinement and strengthening the solidarity of Yeoheon's students. His family had close relationship with Yeoheon, and he started to receive instructions from Yeoheon in his early ages. Owing to the close relationship with Yeoheon, Nam pa did the leading role in the memorial projects, such as publishing the collection of works, and enshrining Yeoheon's tablet in Seowon, a private academy. Especially, he defined Yeoheon's scholarstic mantle as 'assertion that does not come from the teacher whom specifies(不由師承論)' and tried to link Yeoheon's work with other confucian saints' works. This linkage functioned as a stepstone for the projects of enshrining Yeoheon in the memorial hall of their private school, Seowon. Accordingly, in this paper, Nampa's life and academic activities are investigated, considering he was in the middle of the turmoil of separation and conflict of Yeongnam confucian group. Specifically, Nampa was most actively involved in the project of enshrining Yeoheon, and he defined Yeoheon's scholaristic mantle as 'assertion that does not come from the teacher whom specifies(不由師承論)'. Basing on this understanding, he pushed ahead the controversial project of enshrining Yeoheon's tablet in Imgo Seowon(臨皐書院). Although Nampa's scholaric key concepts cannot be found clearly, he tried to diffuse Yeoheon's academic thought over other regions, and by this activity, he tried to solidify Yeoheon's scholarstic achievement and status. His activity confirms that he was most distinctive student of Yeoheon. Ultimately, He was the central figure of late times of Yeoheon school, comparing to the most prestigious fifteen scholars(樑頌十五賢) and ten scholars(旅門十哲) who represented the early times of Yeoheon school.

• Journal of Biomedical and Translational Research
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• v.19 no.4
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• pp.116-124
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• 2018

Korean Native Pig (KNP) has a uniform black coat color, excellent meat quality, white colored fat, solid fat structure and good marbling. However, its growth performance is low, while the western origin Yorkshire pig has high growth performance. To take advantage of the unique performance of the two pig breeds, we raised crossbreeds (KNP ${\times}$ Yorkshire to make use of the heterotic effect. We then analyzed the liver transcriptome as it plays an important role in fat metabolism. We sampled at two stages: 10 weeks and at 26 weeks. The stages were chosen to correspond to the change in feeding system. A total of 16 pigs (8 from each stage) were sampled and RNA sequencing was performed. The reads were mapped to the reference genome and differential expression analysis was performed with edgeR package. A total of 324 genes were found to be significantly differentially expressed (${\left|log2FC\right|}$ > 1 & q < 0.01), out of which 180 genes were up-regulated and 144 genes were down-regulated. Principal Component Analysis (PCA) showed that the samples clustered according to stages. Functional annotation of significant DEGs (differentially expressed genes) showed that GO terms such as DNA replication, cell division, protein phosphorylation, regulation of signal transduction by p53 class mediator, ribosome, focal adhesion, DNA helicase activity, protein kinase activity etc. were enriched. KEGG pathway analysis showed that the DEGs functioned in cell cycle, Ras signaling pathway, p53 signaling pathway, MAPK signaling pathway etc. Twenty-nine transcripts were also part of the DEGs, these were predominantly Cys2His2-like fold group (C2H2) family of zinc fingers. A protein-protein interaction (PPI) network analysis showed that there were three highly interconnected clusters, suggesting an enrichment of genes with similar biological function. This study presents the first report of liver tissue specific gene regulation in a cross-bred Korean pig.

• Cross-Cultural Studies
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• v.25
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• pp.107-129
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• 2011

This article aims to observe the role of Arabic and analyze the future of Arabic in France under the base of the Al-Sabhan Rabina Baldhawe's article, published in mettre l'importance sur University Paris 8 in 2007. In the first part, we have focus into the historical analysis: in France, with a few Arabic and French policy has been settled for what were examined. Also enable the use of Arabic in France with regard to trends of Maghreb countries and other Arab countries, is being led by noted. In the second part, we put on the importance about the situation of Arabic in the France's educational institution. And we have analysed the reasons why Arabic became the most important reason for learning the target language: - in order to faciliate the children of immigrants living in Maghreb able to speak French - Due to differences in culture and language experience to relieve the psychological insecurity above sea - By using the Arabic language at home among family members, strengthen solidarity and resolve heterogeneity In the third part, we have recognized that the French education system was looked at in the Journal of Arabic teaching elementary, middle and high school courses, separated by a learning Arabic as the target language. Finally, we have tried to find a way to revitalize Arabic in France in connection with Sabhan Rabina Al-Baldhawe concrete example of the paper were based on a survey. France and the Arab countries' relationship has been long enough to prove the historic aspects and economic cooperation have maintained a relationship even tighter. Arabic, many of the French people also need education and children to learn Arabic in the French educational institution that has shown a positive stance. French students learning Arabic as a future career in choosing the width of the wider benefits it helps to have. Learning Arabic in the course need to be addressed is also true that a lot of points. But the Arabic and various aspects of internal organization is considered a minority in the popular Arabic language training in France has become more competitive in research and analysis to be active stance is required externally, such as the increase of trade agreements and economic systems side at the level of cultural exchange and international co-operation system, strengthening its position as the Arabic language in France.

• Korean Journal of Social Welfare Studies
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• v.49 no.4
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• pp.101-129
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• 2018

This study examined the overall effect size of the batterer intervention programs aimed at reducing violent behavior. This study calculated the 18 results and the 115 effect sizes of 11 theses published from 2000 to 2017 in Korea. It was demonstrated that the effect of an offender's program on the change in violent behavior was significant at both the practical and treatment level. The effect size was high in the order of control behavior, emotional violence, and physical violence. The effects of dependent variables other than violence were also researched. The batterer program positively changed the participant's attitudes in terms of sex-role and partner violence. Furthermore, it decreased the level of anger and depression, and enhanced self-esteem and communication skills thus increasing satisfaction in marital relationships. In addition, this study examined the factors that influence the effect of the offender's program in terms of the decrease of violent behavior. Upon analysis, it was examined that the moderating effect was great in the approach model and counsel form. More specifically, it was revealed that the feminist-cognitive behavioral models had a greater effect than the compromise model or single model. In terms of counsel forms, group counseling formed only of male offenders had greater effect than couples treatment group. Based on these findings, this study discussed the practical means for increasing the effect of batterer intervention programs.

• Korea journal of population studies
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• v.9 no.2
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• pp.67-78
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• 1986

With Economic Development Plan, the Korean National Family Plan Program was introduced in early 1960's. The program, which has been a way for constraining population increase, has obtained excellent results. In other word, it has had an important role in controlling the increase in population. The purpose of this study is to analyze the change of fertility rates since 1970 and the lever of completed fertility of Korean women since 1960. There are Age-specific Fertility Rate(ASFR), Total Fertility Rate(TFR), Gross Reproduction Rate(GRR) and Net Reproduction Rate(NRR) etc. in indices of period fertility. It is also possible to be seen the completed fertility rates by using Parity Progression Ratio. The data necessary for this study were obtained from Population & Housing Census Report from the year of 1960 to 1980 and Vital Statistics from 1980 to 1984, which conducted by Economic Planning Board, Republic of Korea. The summarized results of this study were as follows : 1. Age-specific Fertility Fertility Rate(ASFR) has been continuously decreasing till now. The ASFR for the women aged 25 to 29 was higher than those of any other groups and the ASFR for the women aged 20 to 24 was higher than that of the women aged 30 to 34 since the mid 1970's. 2. There are Total Fertility Rate(TFR), Gross Reproduction Rate(GRR) and Ney Reproduction Rate(NRR) etc. in reproduction rates. First of all, TFR and GRR have been declining except late of 1970's and TFR showed 2.23 per ever-married women, GRR was 1.05 in 1982. Next, the change of NRR could not be found without life table by year and only NRR for the time of census was to be found. In 1980, NRR showed 1.27 per ever-married women and the level was still out of reach at replacement level of population. 3. Specific Fertility Rate by Birth Order(SFRBO) showed to be declined continually since 1972. Especially the SFRBO of the third live birth was decreased from about 22 per 1,000 ever-married women in 1972 to 12 or so in 1982. 4. To know the level of completed fertility, the mean number of completed live births per ever-married women was calculated from 1960 to 1980. The number of completed live births was more than 5 per ever-married women by the year of 1975 but have been declining and resulted in 4.69 in 1980.

• Journal of Conservation Science
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• v.37 no.5
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• pp.516-524
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• 2021

The 'artist's intention' plays an important role in the conservation process of contemporary art. Accordingly, the information on artworks owned by the artist, their bereaved family members, and foundations that have decision-making power is important. The artist's interview is the kind of data that can clear 'artist's intentions' to ensure reliable conservation treatment can be carried out even after the artist's death. Therefore, this study attempted to use information from the artist's interview on the type of wood in the manufacture of the filler required for lifted and separated bark conditions in the conservation process of wooden artwork in the National Museum of Modern and Contemporary Art. While the conservation treatment resulted in the stable preservation of the bark of artwork, an analysis of the wood confirmed that the information in the artist's interview was not true. Consequently, we suggest that attention must be paid toward the information provided by artist, their bereaved families, etc. Based on the result of this study, this is also expected to help preserve upcoming artworks with similar bark conditions.

• Journal of Life Science
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• v.31 no.9
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• pp.856-861
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• 2021

CD82/KAI1, identified as a metastasis suppressor, was initially known only as a molecular facilitator, but its various functions have recently been revealed. CD82 plays an important role in the stem-progenitor cell, angiogenesis, and muscle. We would like to introduce the recently reported functions and roles of CD82 in this review. CD82 is a member of the tetraspanin family, which consists of four transmembrane domains. The interaction between CD82 and cell adhesion molecules suppresses the metastasis of cancer. CD82 regulates the cell cycle of stem-progenitor cells in the stem cell niche. In the bone marrow, CD82 is expressed on long-term repopulating hematopoietic stem cells (LT-HSCs), which show multipotent differentiation potential. The interaction between CD82 and Duffy antigen receptor for chemokines (DARC) induces quiescence in LT-HSCs. CD82 also regulates Rac1 activity, resulting in the homing and engraftment of HSCs into the bone marrow niche. Besides, CD82 maintains the differentiation potential of muscle stem cells and prevents angiogenesis by inhibiting the expression of cytokines, such as IL-6 and VEGF and adhesion molecules in endothelial cells. CD82 is a key membrane protein that distinguishes the hierarchy of stem-progenitor cells, and is also important for amplification and verification of cellular resources. Further studies on the function of CD82 in various organs and cells are expected to advance cell biology and cell therapy.

• 한국사회정책
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• v.25 no.3
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• pp.279-303
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• 2018

Since the introduction of the Riester Pension Scheme, the controversy has continued in the policy studies and the political debates. This study evaluates the achievements and limitations of the German Riester pension scheme and tries to derive policy implications for South Korea. As a result of the analysis, the most worthwhile achievement of the Riester Pension is to strengthen the role of the private pension schemes. Unlike other private pension schemes, it included a large part of lower income households. It also opened a new perspective of utilizing private pension schemes to accomplish the goals of the family policy. Despite these attainments, it does not reach the promised coverage rate. It also was revealed that the higher income households have concluded more Riester Pension Contracts than the targeted lower-income households. Due to high administration fee and incomplete information problems, benefit levels are supposed to be much lower than expected. It concludes, above all, despite some achievements, the Riester Pension Scheme will not fill completely the gap of old age income security caused by the reduction of the public pension system. The German case provides fruitful lessons for Korea. The introduction of a subsidized personal pension scheme in South Korea can be realized only when some prerequisites would be satisfied such as the consolidation and maturing of public pension schemes and the strengthening of the transparency in the private pension market.

• Journal of vocational education research
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• v.37 no.4
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• pp.67-89
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• 2018

The purpose of this study is to analyze the role of career flexibility on employment status, career growth, and job satisfaction longitudinally. Demographic information(gender, age, parent's income level, and students' perceived financial states of family), vocational identity, employment status, career growth, and job satisfaction at 1, 2, and 3 years after the first data collection with a sample of 259(time 1), 229(time 2), 182(time 3) were collected respectively. Multivariate regression and logistic regression analysis were performed. Results showed that in-breadth career exploration positively predicted to employment status at time 1, 2, 3 consistently and career flexibility also positively predicted to employment status at time 2, 3. The longitudinal effect of career flexibility was found that the expectancy of career flexibility had shown to have stronger effect. In addition, career growth was influenced by in-depth career exploration at time 2, 3. On the other hand, no variables were related to job satisfaction in this study. Results of the current study provided the new insights for career education and limitation and future suggestions were discussed.

• Nutrition Research and Practice
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• v.12 no.6
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• pp.494-502
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• 2018

BACKGROUND/OBJECTIVES: Reducing the number of adipocytes by inducing apoptosis of mature adipocytes as well as suppressing differentiation of preadipocytes plays an important role in preventing obesity. This study examines the anti-adipogenic and pro-apoptotic effect of red pepper seed water extract (RPS) prepared at $4^{\circ}C$ (RPS4) in 3T3-L1 cells. MATERIALS/METHODS: Effect of RPS4 or its fractions on lipid accumulation was determined in 3T3-L1 cells using oil red O (ORO) staining. The expressions of AMP-activated protein kinase (AMPK) and adipogenic associated proteins [peroxisome proliferator-activated receptor-${\gamma}$ ($PPAR-{\gamma}$), CCAAT/enhancer-binding proteins ${\alpha}$ (C/EBP ${\alpha}$), sterol regulatory element binding protein-1c (SREBP-1c), fatty acid synthase (FAS), and acetyl-CoA carboxylase (ACC)] were measured in 3T3-L1 cells treated with RPS4. Apoptosis and the expression of Akt and Bcl-2 family proteins [B-cell lymphoma 2 (Bcl-2), Bcl-2-associated death promoter (Bad), Bcl-2 like protein 4 (Bax), Bal-2 homologous antagonist/killer (Bak)] were measured in mature 3T3-L1 cells treated with RPS4. RESULTS: Treatment of RPS4 ($0-75{\mu}g/mL$) or its fractions ($0-50{\mu}g/mL$) for 24 h did not have an apparent cytotoxicity on pre and mature 3T3-L1 cells. RPS4 significantly suppressed differentiation and cellular lipid accumulation by increasing the phosphorylation of AMPK and reducing the expression of $PPAR-{\gamma}$, C/EBP ${\alpha}$, SREBP-1c, FAS, and ACC. In addition, all fractions except ethyl acetate fraction significantly suppressed cellular lipid accumulation. RPS4 induced the apoptosis of mature adipocytes by hypophosphorylating Akt, increasing the expression of the pro-apoptotic proteins, Bak, Bax, and Bad, and reducing the expression of the anti-apoptotic proteins, Bcl-2 and p-Bad. CONCLUSIONS: These finding suggest that RPS4 can reduce the numbers as well as the size of adipocytes and might useful for preventing and treating obesity.