• 대한가정학회지
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• 제40권1호
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• pp.23-35
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• 2002

The purpose of this study was to examine the personal, familial, school and peer characteristics related to adolescents' runaway drive. The 259 subjects were selected from high school student in the city of Daegu. The major findings of study were as follows: 1. In respect of personal characteristics, the more runaway drive was, the lower self-esteem was and the higher anxiety, depression, and impulsive mind was. 2. In respect of familial characteristics, the more runway drive was, the lower family cohesion and family adaptation was and the higher the degree of parents' rejection was. And the higher runway drive was, the higher degree of child abuse and interparental conflict. 3. In respect of school characteristics, the more runway drive was, the lower school adaptation was. 4. In respect of peer characteristics, the more runway drive was, the higher degree of delinquency of peer.

• Journal of Korean Neurosurgical Society
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• 제53권1호
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• pp.1-5
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• 2013

Objective : The purpose of this study was to evaluate the characteristics and surgical outcomes of familial hemifacial spasm (HFS) and to discuss the role of genetic susceptibility. Methods : Between 2001 and 2011, 20 familial HFS patients with ten different pedigrees visited our hospital. The data from comprehensive evaluation of these patients, including clinical, radiological and electrophysiological data and surgical outcomes were reviewed to characterize familial HFS and to compare the characteristics between familial HFS and sporadic HFS. Results : According to the family tree, the inheritance pattern was difficult to define clearly using these data. Radiologic findings suggested that the vertebral artery (VA) was a more frequent offender in familial HFS than in sporadic cases (35.0% vs. 10.0%, p<0.001). Chi-square test showed that there were no correlation between VA tortuosity and underlying morbidity such as diabetes or hypertension (p=0.391). Eighteen out of 19 patients who underwent microvascular decompression showed no residual spasm. Other features of familial HFS overlap with sporadic cases. These findings suggest that certain genetic susceptibilities rather than hypertension or diabetes may influence vascular tortuosity and HFS development. Conclusion : In this study, familial HFS seems not so different from sporadic cases. Authors thought familial HFS could have heterogeneous etiology. Further study of familial HFS including clinical, anatomic, genetic, and molecular information may help identify a gene or trait that can provide insight into the mechanisms of sporadic and familial HFS.

• International Journal of Human Ecology
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• 제6권1호
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• pp.103-115
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• 2005

This study utilized data (a sample of 18,553 people born in 1958 in England, Scotland, and Wales) from the National Child Development Study of 1968 and 1991 to explore the influence of familial difficulties on the internalizing behavioral patterns during the early adolescent period and late life outcomes periods. In this paper, internalizing behavioral problems include 'depression', 'anxiety', 'hostility to adults', 'hostility to children', and 'withdrawal'. Late outcomes were analyzed in two different variables and one marital management domain: 'unemployment', 'seen doctors about emotional problems', 'divorce or separation; never lived as a couple; arguments end in violent behavior' The results indicate that young adolescents who had experienced familial difficulties also have internalizing behavioral problems giving them emotional and behavioral instability. The findings also show that familial difficulties during childhood positively contribute to late life outcomes such as unemployment, emotional problems, and marital management. This study suggests that in order to effectively respond to the needs of children and adolescents who have experienced various familial difficulties, counselors and educators must guide parents.

• 한국콘텐츠학회논문지
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• 제12권6호
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• pp.265-279
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• 2012

본 연구에서는 노인의 자살 생각에 영향을 미치는 생태체계요인에 관해서 알아보고 특히 중증 만성 질환자를 돌보는 노인의 자살생각에 영향을 미치는 생태체계요인에 대해서 분석하였다. 생태체계요인은 개인적 체계, 가족적 체계, 사회적 체계를 선정하여 인구사회학적특성과 함께 투입하여 자살생각에 미치는 영향을 살펴보았다. 연구대상은 경기도에 거주하고 있는 55세 이상의 중증 만성질환자를 돌보는 노인 274명을 대상으로 하였다. 자료 분석은 SPSS 18.0 프로그램을 이용하여 빈도분석, 요인분석, 신뢰도분석, t-test 및 분산분석, seheffe test와 위계적회기 분석을 하였고 연구결과는 다음과 같다. 첫째, 개인적 체계가 자살생각에 미치는 영향을 측정하기 위해서 개인적 특성 및 부양부담감 을 독립변수로 선정하여 자살생각에 미치는 영향을 분석한 결과 두 변수 모두 유의하였으며, 둘째, 가족적 체계는 가족적 특성과 가족적 지지로서 간병기간이 길수록, 가족의 지지가 적을수록 자살생각에 미치는 영향이 컸다. 셋째, 사회적 체계 면에서는 사회적 지지와 사회활동참여도를 독립변수로 적용한 결과 사회적 지지의 모든 요인이 자살생각에 부(-)적 영향을 주었으나 사회활동 참여도의 영향력은 없는 것으로 분석되었다.

• 가정과삶의질연구
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• 제20권3호
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• pp.1-12
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• 2002

This study was conducted to examine the relationship between socio-familial characteristics and health status in early stage of elderly life. In this study, a total of 252 Korean males and females aged 55 to 74 were interviewed to obtain information on various socio-familial characteristics such as age, gender, residence, marital status, education, religion, distance with children, household size, and living arrangements. They were also examined for self-perceived depression and diagnosed health problems. The analysis of the results show that marital status, gender, and living arrangement were major characteristics differentiating health status; widowed women living apart from their children are at lower level for most items of hea1th status such as emotional, circulatory, respiratory, digestive, and muscle and skeletal function. Based on this analysis, suggestions are made for efficient health management. First, widowed females living without children are encouraged to participate in regular health promotion programs in self-organized groups. Second, usual welfare service programs need to be segregated for each age group, so that relatively young elderly are not frustrated from being treated together with extremely frail older elderly. Third, low education group living in rural area are offered preventive medical services for muscular and skeletal related health problems.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제28권3호
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• pp.168-173
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• 2017

Objectives: Adolescent depression is a complex disorder influenced by a variety of personal and familial factors. In this study, we compared the familial, cognitive, and behavioral characteristics of adolescents with and without diagnosed depression. Methods: Forty adolescents with depressive disorder were recruited from two psychiatric clinics, along with 46 healthy adolescents from a middle school and a high school. We then compared the participants' cognitive and behavioral characteristics and the child-rearing attitudes of their parents. Results: Compared to the healthy adolescents, the adolescents with depression exhibited lower self-esteem, higher emotional reappraisal, greater disruptive behavior, and lower attention. Furthermore, compared to the mothers of the healthy adolescents, the mothers of those with depression reported less affective, less autonomic, and more rejecting parenting attitudes towards their children. Conclusion: We found that attentional problems, negative parenting attitudes, negative self-cognition, and expressive suppression are all associated with adolescent depression. Parenting education and interventions appear to be needed to correct the negative cognitions of adolescents with depression.

• 여성건강간호학회지
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• 제26권1호
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• pp.84-92
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• 2020

Purpose: The objective of this study was to identify the factors influencing maternal identity in pregnant women. Methods: Using a descriptive research design, a cross-sectional survey was conducted. In total, 127 pregnant women were recruited from a tertiary hospital in Korea from January to April 2019. Measurements included maternal identity, stress, depression, spousal and familial support, and demographic and obstetric characteristics. Data were analyzed by descriptive statistics, the independent t-test, one-way ANOVA, Pearson correlation coefficients, and stepwise multiple regression using SPSS version 25.0. Results: The mean score for maternal identity was 131.15 out of 160, and the mean scores for stress, depression, and spousal and familial support were 14.59 (out of 40), 6.82 (out of 30), and 109.04 (out of 132), respectively. Stress (r=-.38, p<.001), depression (r=-.37, p<.001), and spousal and familial support (r=.37, p<.001) were significantly correlated with maternal identity. In multiple regression analysis, stress (β=-0.27, p=.005) and spousal and familial support (β=0.23, p=.014) were found to be significant factors influencing maternal identity in pregnant women (F=14.19, p<.001). Conclusion: It is necessary to develop effective strategies to mitigate stress and to encourage spousal and familial support in pregnant women. Such strategies could further enable pregnant women to enhance their maternal identity.

• Journal of Korean Neurosurgical Society
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• 제44권3호
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• pp.136-140
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• 2008

Objective : Numerous studies have compared the characteristics of familial intracranial aneurysms with those of non-familial aneurysms. To better understand familial subarachnoid hemorrhage (SAH), we studied a series of patients with SAH who had at least one first-degree relative with SAH, and compared our results with those of previous studies. Methods : We identified patients treated for SAH at our hospital between January 1993 and October 2006 and analyzed those patients with one or more first-degree relatives with SAH. We retrospectively collected data from patients with a family history and searched for patients who had relatives with aneurysms or who had been treated at other hospitals for SAH. Results : We identified 12 patients from six families with at least two first-degree relatives with SAH. All patients had affected first-degree relatives; in five families, they were siblings. The mean age at the time of rupture was 49.75 years; in four families, the age difference was within 5 years. In five patients (42%), the aneurysm was located in the middle cerebral artery. Only one patient had an aneurysm in the anterior communicating artery. Conclusion : In agreement with previous studies, our results showed that familial aneurysms, in comparison with non-familiar aneurysms, ruptured at a younger age and smaller size, had a high incidence in the middle cerebral artery, and were underrepresented in the anterior communicating artery. Interestingly, the age at the time of rupture was similar between relatives. Screening should be considered in the fifth or sixth decade for those who have a sibling with SAH.

• 디지털융복합연구
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• 제13권4호
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• pp.405-416
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• 2015

본 연구는 전국의 장애여성 374명을 조사대상자로 하여 융복합 사회에서의 장애여성의 안전에 대한 설명요인을 탐색하는데 목적이 있다. 본 연구에서는 안전을 '사고로부터 안전'과 '범죄로부터 안전'으로 구분한 후, 개인, 가족, 지역사회 요인들이 장애여성이 경험하고 있는 안전을 어떻게 설명하는지 분석하였다. 주요 결과는 다음과 같다. 1) 장애여성이 경험하는 '사고로부터 안전'에 대한 설명력이 가장 큰 요인은 지역사회 영역으로 지역 유형과 사회적 자본 수준, 물질적 곤궁, 장애정도가 유의하게 영향을 미치는 요소로 나타났다. 다음으로는 가족 영역의 물질적 곤궁과 개인 영역의 장애수준이 장애여성의 사고로부터 안전을 설명하는 요인으로 분석되었다. 2) 장애여성의 '범죄로부터 안전'에 대한 설명력이 가장 큰 요인은 가족 영역의 물질적 곤궁이었고, 지역사회 영역에서는 지역사회 유형, 사회적 지지가, 개인 영역에서는 교육 수준이 장애여성의 범죄로부터 안전을 설명하는 유의한 요인으로 나타났다. 이러한 결과를 근거로 장애여성의 안전을 확보하기 위한 융복합적으로 실천적이고 정책적인 접근방안을 제언하였다.

• BMB Reports
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• 제43권4호
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• pp.233-244
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• 2010

Parkinson's disease (PD) is the second most common neurodegenerative disease, and 5-10% of the PD cases are genetically inherited as familial PD (FPD). LRRK2 (leucine-rich repeat kinase 2) was first reported in 2004 as a gene corresponding to PARK8, an autosomal gene whose dominant mutations cause familial PD. LRRK2 contains both active kinase and GTPase domains as well as protein-protein interaction motifs such as LRR (leucine-rich repeat) and WD40. Most pathogenic LRRK2 mutations are located in either the GTPase or kinase domain, implying important roles for the enzymatic activities in PD pathogenic mechanisms. In comparison to other PD causative genes such as parkin and PINK1, LRRK2 exhibits two important features. One is that LRRK2's mutations (especially the G2019S mutation) were observed in sporadic as well as familial PD patients. Another is that, among the various PD-causing genes, pathological characteristics observed in patients carrying LRRK2 mutations are the most similar to patients with sporadic PD. Because of these two observations, LRRK2 has been intensively investigated for its pathogenic mechanism (s) and as a target gene for PD therapeutics. In this review, the general biochemical and molecular features of LRRK2, the recent results of LRRK2 studies and LRRK2's therapeutic potential as a PD target gene will be discussed.