• The Journal of the Korea Contents Association
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• v.12 no.6
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• pp.265-279
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• 2012

In this study, I tried to find out the ecosystem factors which influence suicide thoughts of elderly that care for a chronic invalid. Ecosystem factors are consist of personal system, familial system and social system, tried to analysis ecosystem factors with characteristics of social population that influence suicide thoughts. For the study, I collected 274 samples from people of 55 year-old care a chronic invalid adults who reside of in Gyeonggi-do. I used factor analysis, reliability analysis, multi-regression, t-test, ANOVA with SPSS 18.0. The results are as follows. First, suicide thoughts had affected by personal characteristics and the duty of supporting selected independent variable. Second, familial system as familial characteristics and familial support had a strong influence on suicide thoughts by long-term care and deficient familial support. Third, the result of study, social support and participation of social activities apply as independent variable then every factors of social support are negative influence but participation of social activities are not influence.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.10 no.2
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• pp.195-200
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• 1999

Objective：This study was to investigate the effects of familial risk factors on the behavior problems of ADHD group and normal group. Method：The familial risk factors and behavioral problems of the children were administered to 160 mothers, comprised of 29 ADHD children and 131 normal children. Results：The results showed that the ADHD group and normal group were significantly different in the degree of marital satisfaction, state-trait anxiety, and depression. Familial risk factors and the behavior problems of children were significantly correlated. Conclusion：Marital unsatisfaction and parental affective problems were closely related to behavior problems of ADHD patients.

• Journal of Nutrition and Health
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• v.27 no.5
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• pp.460-472
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• 1994

Prevalences of hypertension and obesity of primary school children in Kangnung were investigated, and the correlations between blood perssure and measured anthropometry were also studied to identify the factors that influence on blood pressure. 1,164 children (602 boys and 562 girls) from five elementary schools were chosen for this study. Anthropometric measurements were taken for blood pressure, body weight, height, triceps skinfold, and circumferences of chest and arm. Data of family history of hypertension were obtained by means of prepared questionnaires. Prevalences of hypertension were 3.3% in boys and 3.1% in girls. The group with elevated blood pressure had relatively a greater frequency of familial hypertension and significantly higher mean body weight and obesity index. The prevalence of obesity was defined as percentage of children whose rates of current weight to standard weight for height and sex in Korean children were more than 120%. Prevalence of obesity were 16.3% in boys, 10.3% in girls. There findings clearly revealed the influences of above-average weight and familial hypertension on blood pressure. These results suggest that children with familial hypertension should be avoid excess adiposity and be measured blood pressure regularly.

• Clinical and Experimental Pediatrics
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• v.52 no.6
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• pp.643-648
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• 2009

Blood eosinophilia can be classified as either familial or acquired. Familial eosinophilia is a rare autosomal dominant disorder characterized by a stable eosinophil count. Acquired eosinophilia is classified further into a primary or secondary phenomenon depending on whether eosinophils are considered integral to the underlying disease. Primary eosinophilia is considered clonal in the presence of either a cytogenetic abnormality or bone marrow histological evidence of classified hematologic malignancies. Causes of secondary eosinophilia include infections, allergic or immunologic disorders, and drugs. Idiopathic eosinophilia belongs to a category of primary eosinophilia, and this is a diagnosis of exclusion. Cases with eosinophilia that lack evidence of clonality may be diagnosed as idiopathic hypereosinophilic syndrome after all causes of reactive eosinophilia have been eliminated. Genetic mutations involving the platelet-derived growth receptor genes (PDGFRA and PDGFRB) have been pathogenetically linked to clonal eosinophilia, and their presence predicts the treatment response to imatinib. In this review, I will present a clinical summary of both familial and acquired eosinophilia with emphasis on recent developments in molecular pathogenesis and treatment.

• Journal of Chest Surgery
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• v.13 no.2
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• pp.105-109
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• 1980

Tetralogy of Fallot has shown its familial aggregation in several familial studies. This reported case is another example which occurred in a family in two brothers. They revealed no cytogenetic abnormalities, but the anatomical cardiac malformation of them showed much similarity, total conal defect in ventricular septum and .one had patent foramen ovale, the other atrial septal defect. The familial recurrence tendency of Tetralogy of Fallot as well as other congenital heart diseases could be explained on multifactorial inheritance as shown in many reports. In spite that we couldn`t find out any environmental trigger or teratogens, our case may be accepted on the base of multifactorial mechanism.

• Clinical and Experimental Pediatrics
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• v.57 no.1
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• pp.1-18
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• 2014

Channelopathies are a heterogeneous group of disorders resulting from the dysfunction of ion channels located in the membranes of all cells and many cellular organelles. These include diseases of the nervous system (e.g., generalized epilepsy with febrile seizures plus, familial hemiplegic migraine, episodic ataxia, and hyperkalemic and hypokalemic periodic paralysis), the cardiovascular system (e.g., long QT syndrome, short QT syndrome, Brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia), the respiratory system (e.g., cystic fibrosis), the endocrine system (e.g., neonatal diabetes mellitus, familial hyperinsulinemic hypoglycemia, thyrotoxic hypokalemic periodic paralysis, and familial hyperaldosteronism), the urinary system (e.g., Bartter syndrome, nephrogenic diabetes insipidus, autosomal-dominant polycystic kidney disease, and hypomagnesemia with secondary hypocalcemia), and the immune system (e.g., myasthenia gravis, neuromyelitis optica, Isaac syndrome, and anti-NMDA [N-methyl-D-aspartate] receptor encephalitis). The field of channelopathies is expanding rapidly, as is the utility of molecular-genetic and electrophysiological studies. This review provides a brief overview and update of channelopathies, with a focus on recent advances in the pathophysiological mechanisms that may help clinicians better understand, diagnose, and develop treatments for these diseases.

• Korean Journal of Veterinary Research
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• v.47 no.2
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• pp.255-257
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• 2007

Familial renal amyloidosis was found in a four-year-old male Shar Pei dog. The dog had intermittent fever with signs of renal failure. Another sibling of this dog also showed subclinical signs of renal amyloidosis. Despite aggressive therapy with peritoneal dialysis, the dog died after 10 days of the first presentation. With special staining for amyloid, the renal amylodosis was confirmed.

• International Journal of Human Ecology
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• v.5 no.1
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• pp.1-8
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• 2004

The current study uses longitudinal data, which show secondary school students' responses in a biennial data of surveys from England (n=4,326/boys=2,313;girls=2,413) and Scotland (n=3,528/boys=1,744;girls=1,784), to describe the association between availability of cigarette sales to minor, prosmoking attitudes of family members and drinking/drug use and smoking behaviours amongst adolescents. The findings provided strong evidence suggesting that availability of cigarette sales to minor, lack of familial interest on the child's smoking and other substance use were positively associated with the increased level of smoking behaviour in youth. Girls and boys also differed the likelihood of smoking and being a regular smoker. Boys were found to be more likely than girls to be smoking and to be a regular smoker. The implications of promising prevention programmes for preadolescents and areas for future research are presented

• Imaging Science in Dentistry
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• v.36 no.3
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• pp.157-162
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• 2006

Familial gigantiform cementoma is a rare fibre-cemento-osseous disease of the jaws which appears to be transmitted as an autosomal dominant trait with variable expressivity of the phenotype. A 7-year-old girl visited DKUDH complaining of the painless facial deformity. Clinically, significant facio-lingual expansion was observed at the left maxilla, left mandibular body and symphysis portion. Malposition of lower anterior teeth was found. Panoramic radiograph and CT scan showed the extensive expansile mixed lesion at maxilla and mandible. Bone scan revealed hot spot at the maxilla and left side of mandible. Histologic examination revealed moderately dense fibrous connective tissue with scattered masses resembling cementum. The patient's mother had a history of the mandibular resection due to benign tumor. Her younger brother had buccal expansion of right mandible. We report our finding of a family that has exhibited clinical, radiographic and histologic findings consistent with the familial gigantiform cementoma.

• Journal of Audiology & Otology
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• v.25 no.4
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• pp.230-234
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• 2021

Otosclerosis, a hereditary disorder characterized by disordered resorption and deposition of bone, results in progressive hearing loss. Osteogenesis imperfecta (OI) is a genetic disorder characterized by recurrent fractures, blue sclera, and varying degrees of hearing impairment; and is a known risk factor for otosclerosis. After adolescence, the risk of fracture decreases, reducing the need for follow-up in OI. However, otosclerosis is a progressive disorder. In this report, we discuss two cases of familial otosclerosis with different clinical features. We hypothesize that the difference in hearing level correlates with the difference in computed tomography findings. The mother, whose case was considered severe, was prescribed hearing aids, while the daughter, who had normal hearing level, was regularly followed up.