• Journal of Korean Neurosurgical Society
• /
• 제44권3호
• /
• pp.136-140
• /
• 2008

Objective : Numerous studies have compared the characteristics of familial intracranial aneurysms with those of non-familial aneurysms. To better understand familial subarachnoid hemorrhage (SAH), we studied a series of patients with SAH who had at least one first-degree relative with SAH, and compared our results with those of previous studies. Methods : We identified patients treated for SAH at our hospital between January 1993 and October 2006 and analyzed those patients with one or more first-degree relatives with SAH. We retrospectively collected data from patients with a family history and searched for patients who had relatives with aneurysms or who had been treated at other hospitals for SAH. Results : We identified 12 patients from six families with at least two first-degree relatives with SAH. All patients had affected first-degree relatives; in five families, they were siblings. The mean age at the time of rupture was 49.75 years; in four families, the age difference was within 5 years. In five patients (42%), the aneurysm was located in the middle cerebral artery. Only one patient had an aneurysm in the anterior communicating artery. Conclusion : In agreement with previous studies, our results showed that familial aneurysms, in comparison with non-familiar aneurysms, ruptured at a younger age and smaller size, had a high incidence in the middle cerebral artery, and were underrepresented in the anterior communicating artery. Interestingly, the age at the time of rupture was similar between relatives. Screening should be considered in the fifth or sixth decade for those who have a sibling with SAH.

• 한국산학기술학회논문지
• /
• 제11권7호
• /
• pp.2436-2443
• /
• 2010

본 연구는 현 우리나라에서 가족관광시 발생되는 갈등유발요인을 규명함으로써, 가족간의 갈등유발요인의 예측은 물론 이를 통해 변화된 가족관광시 상이한 갈등유발요인확인은 관광행동을 연구하는 기초자료를 제공하고자 하였다. 이에 본 연구를 통하여 첫째, 관광학 측면 즉, 관광객행동론 이해측면에서 가족관광시 가족생애주기별 의사결정자와 각 구성원들간 상이한 갈등유발요인을 규명하였다. 이를 통하여 첫째, 가족관광의사결정시 각 이해관계자들 간의 의사소통이 원활해 질 것으로 기대할 수 있다. 둘째, 각 이해관계자들의 의견수렴으로 상호간의 신뢰를 얻을 수 있을 것으로 기대 할 수 있다. 셋째, 가족간의 갈등유발요인의 예측으로 가족간의 의사결정시 시행착오를 예방할 수 있을 것으로 기대할 수 있을 것으로 사료된다.

• 대한족부족관절학회지
• /
• 제16권2호
• /
• pp.108-115
• /
• 2012

Purpose: To evaluate several risk factors related to re-ulceration of diabetic foot including psychosocial aspects such as familial support and degree of independence of patients' activity. Materials and Methods: We reviewed medical records and performed telephone interview with eighty-five patients who had a history of hospitalization in our hospital due to diabetic foot ulceration from year 2002 to 2010. Based on the collected data, we analyzed several factors such as age, gender, prevalence duration, accompanying diseases, HbA1c level, degree of independence and familial support. Results: The mean age was 61.4 years and most common in the 4th decade. There were 57 cases (67%) of recurrence, predominance of male. Eleven patients with recurrent diabetic foot ulceration had undergone major amputations. Psychosocial problems such as depression, insufficient familial support and mortality were more frequently observed in recurrent group. Conclusion: This study shows that psychosocial factor such as familial support for patient with diabetic foot could be important to reduce the recurrence rate of diabetic foot ulceration. Therefore, we should pay attention to strategic plans for prevention, screening, treatment, and aftercare through the prospective studies including psychosocial risk factor in diabetic foot ulceration.

• Journal of Preventive Medicine and Public Health
• /
• 제23권4호
• /
• pp.428-435
• /
• 1990

This study was designed to investigate whether recruitment of physicians and dentists has been restricted to a social network, such as familial or kinship groups. The data was collected through a self-administered questionnaire survey distributed to a sampling of general physicians, specialists (internists, surgeons, other specialists), and dentists in August 1990. The major findings are as follows : 1) Total number of respondents was 405 ; of these, general physicians made up 48.9%, internists 10.4%, surgeons 15.8%, other specialists 4.9%, and dentists 20.0%. 2) 38.5% of the respondents had physicians or dentists in their immediate family or were related in some way to one. Those from urban areas, whose parents were highly educated, and whose father was a professional had more physicians or dentists in their family or kinship. 3) Parents of 7.1% of the respondents, brothers or sisters of 10.1%, grand parents of 1.7%, uncles or aunts of 7.9%, and cousins of 22.0% were physicians or dentists. 4) The majority of physicians or dentists in familial or kinship network specialized n surge, 32.3%, followed by internal medicine ; current worksites were noted as clinics by 30.8%, followed by general hospital, university hospital, and so on. The respondent's ma discipline tended to follow familial or kinship example. Consequently, it was concluded that physicians and dentists have been recruited within restricted familial or kinship network.

• 대한치과의사협회지
• /
• 제51권8호
• /
• pp.459-467
• /
• 2013

The use of autogenous tooth bone graft material has been commercialized since 2008. Autogenous tooth bone grafts always require that the tooth of the patient be extracted, and thus, the use of graft material are limited in many cases. For solution of limitation in quantity and concurrent use of autogenous tooth bone graft material, the grafting of familial teeth has been suggested. It has the following advantages: the teeth of family members are used as bone graft materials, the genetic composition is identical, and potential genetic and infectious risks can be minimized. Because the teeth of family members are used, a good tissue affinity is obtained, and thus, superior bone generation rates compared to those observed for allogenic or xenogenic bones can be anticipated. We used familial tooth bone-graft materials for alveolar ridge augmentation, socket preservation, and maxillary sinus graft in some cases. In most cases, the impacted third molars of their children were prepared as bone graft material and were used for surgery. In one case, the impacted third molar from the patient's brother was used as bone graft material. We obtained satisfactory result and these cases are reported herein.

• Childhood Kidney Diseases
• /
• 제1권2호
• /
• pp.183-188
• /
• 1997

Familial juvenile hyperuricemic nephropathy is an autosomal dominant disease characterized by progressive renal disease and hyperuricemia or gout, affecting young people of either sex equally. There are two biochemical markers of this disorder. The first is hyperuricemia disproportionate to the degree of renal dysfunction; the second is a grossly reduced clearance of uric acid relative to creatinine, dispropotionate to age, sex and degree of renal failure. We experienced 2 family members with hyperuricemia. One family member, a 13-year-old girl who had suffered from tophaceous gout and chronic renal failure. Her younger brother also had hyperuricemia and moderately reduced renal function. Their urinary excretion fractions of uric acid($FE_{uric\;acid}$) were reduced and renal biopsy specimens showed interstitial fibrosis with tubular atrophy and interstitial urate crystal deposition. We have treated these two patients with allopurinol but we have done renal transplantation because she progressed to end stage renal disease at 16 year old age.

• Child Health Nursing Research
• /
• 제10권3호
• /
• pp.300-310
• /
• 2004

Purpose: To compare normal weight children with obese children in terms of family factors, eating habits, and sociocognitive factors. Method: This study compared 217 obese children with 231 normal standard weight children of 4th-6th graders from 7 elementary schools in Kangwon province. The study also surveyed 817 their parents using questionnaires in which familial factors, eating habits, and sociocognitive factors such as dietary self-efficacy, locus of control and self-esteem were included. Result: Obese children had more obese family members, more family members with chronic metabolic disease, and lower breast-feeding rate than normal weight group. Dietary self-efficacy was positively correlated with eating habits and locus of control while no correlation was found with obesity index.. Self-esteem was negatively correlate with obesity index. Both the parents and the childrens eating habits showed significant positive correlation to the obesity index. Conclusion: These results implied familial factors, eating habits, and sociocognitive factors influenced childhood obesity. Thus, further research targeting to positive attitude toward familial dietary practices combined with significant sociocognitive factors, may lead to prevention and effective management of childhood obesity.

• 대한한방내과학회지
• /
• 제39권4호
• /
• pp.772-783
• /
• 2018

The aims of this study were to use the Rydoraku test, electrogastrography, and enterotachography to examine the presence of familial gastric dysmotility among monozygotic twins and their mothers; to determine the relationship between the symptoms and the indexes of the Rydoraku test, electrogastrography, and enterotachography; and to observe the therapeutic reaction for each differential treatment between twins with familial gastric dysmotility. The same herbal medication (Banhasasim-tang extract three times/day and Sojuckkunbi-tang extract three times/day) was given to each twin, but the younger twin also underwent manual acupuncture on the CV 10, 12, and 13 points of the abdominal wall and electrical stimulation of both ST 36 points of the lower leg 2-3 times per week. Evaluation of the therapeutic effect was followed after six weeks. The presence of familial gastric dysmotility was shown in the autonomic nerve system and gastric muscle and was thought to be a common pathophysiology induced by genetic co-ownership. Only the younger twin showed any marked relief of the dyspeptic symptoms associated with improvement of pyloric sphincter function, which was induced by acupuncture treatment. The Rydoraku test, electrogastrography, and enterotachography results showed the presence of familial gastric dysmotility. Although Korean traditional medicine had no effect on the familiar gastric dysmotility associated with genetic influences, the acupuncture treatment had a beneficial effect on the secondary disorder of pyloric sphincter function, which is associated with the relief of dyspeptic symptoms.

• Clinical and Experimental Pediatrics
• /
• 제59권6호
• /
• pp.280-284
• /
• 2016

Cerebral cavernous malformation (CCM) is a vascular malformation characterized by abnormally enlarged capillary cavities without any intervening neural tissue. We report 2 cases of familial CCMs diagnosed with the CCM1 mutation by using a genetic assay. A 5-year-old boy presented with headache, vomiting, and seizure-like movements. Brain magnetic resonance imaging (MRI) revealed multiple CCM lesions in the cerebral hemispheres. Subsequent mutation analysis of his father and other family members revealed c.940_943 del (p.Val314 Asn315delinsThrfsX3) mutations of the CCM1 gene. A 10-month-old boy who presented with seizure-like movements was reported to have had no perinatal event. His aunt was diagnosed with cerebral angioma. Brain and spine MRI revealed multiple angiomas in the cerebral hemisphere and thoracic spinal cord. Mutation analysis of his father was normal, although that of the patient and his mother revealed c.535C>T (p.Arg179X) mutations of the CCM1 gene. Based on these studies, we suggest that when a child with a familial history of CCMs exhibits neurological symptoms, the physician should suspect familial CCMs and consider brain imaging or a genetic assay.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제8권1호
• /
• pp.91-95
• /
• 2005

HCV의 가족 내 집단 감염은 드물게 발생하며 배우자에서 감염의 위험이 가장 높고 수직 감염의 빈도는 매우 낮게 보고되고 있다. 저자들은 환자와 환자의 어머니, 외할머니, 이모, 이종 사촌 언니에서 HCV 감염이 확인되어 가족 구성원의 50%가 HCV에 감염된 극히 드문 가족 내 집단 감염을 경험하였기에 문헌 고찰과 함께 보고한다.