• The Journal of Internal Korean Medicine
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• v.37 no.2
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• pp.345-351
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• 2016

Objective: This clinical study reports on the effectiveness of traditional Korean medicine on a patient with diplopia and eye-movement impairment caused by brain-stem infarction.Method: A patient with diplopia and eye-movement impairment caused by brain-stem infarction was treated with herbal medicine (Bogan-san), acupuncture, and moxibustion. We used the visual analogue scale (VAS) of diplopia and measured the patient's eye-movement range to evaluate the effectiveness of the treatment.Results: The diplopia VAS decreased and eye-movement range improved after treatment with traditional Korean medicine.Conclusion: This clinical study suggests that traditional Korean medicine could greatly contribute to the treatment of diplopia and eye-movement impairment caused by brain-stem infarction.

• The Journal of Internal Korean Medicine
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• v.33 no.4
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• pp.599-608
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• 2012

Objectives : To report three cases of eye movement impairment: internuclear ophthalmoplegia (INO) due to pontine infarction, traumatic abducens nerve palsy, and abducens nerve involvement in Miller-Fisher syndrome. Cases Summary : There were three cases. First, a 64-year-old woman, who was given a diagnosis of INO due to pontine infarction, had left gaze palsy of her right eye while the convergence was intact. Second, a 34-year-old man had abduction impairment of his right eye after a traffic accident. Third, a 66-year-old man, who was diagnosed with Miller-Fisher syndrome, had left gaze palsy of his left eye. Their symptoms improved substantially and their anxieties were relieved after treatment with herbal medicine and acupuncture. Conclusions : There has been no certain cure for eye movement impairment yet. In this report, we present three successful cases of patients with eye movement impairment and show that Korean medical treatment could be a solution for this incurable disease.

• The Journal of the Society of Stroke on Korean Medicine
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• v.19 no.1
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• pp.41-48
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• 2018

■ Objectives The purpose of this case report is to show the effect of Traditional Korean Medicine (TKM) on a patient with horizontal eye movement disorder due to Foville syndrome. ■ Methods A patient with horizontal eye movement disorder as Foville syndrome was treated with herbal medication, acupuncture, electro-acupuncture and transcutaneous electrical nerve stimulation. Then we evaluated the improvement with mobility impairment, length of movement and House-Brackmann scale before and after treatment ■ Results Improvements of mobility impairment, distance at left gaze and House-Brackmann scale were observed after the TKM treatment. ■ Conclusion This case report shows the effect of TKM treatment on horizontal eye movement disorder due to Foville syndrome.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.3
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• pp.138-152
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• 2020

Objectives : The aim of this study is to report a case of idiopathic oculomotor nerve palsy improved by Korean Medicine therapy including needle-embedding therapy. Methods : We treated a 69-year old male patient who has Rt. ptosis, Rt. eye movement impairment, and dizziness with various Korean medical therapy including acupuncture, Bojungikgitanggami, and Hominis Placenta pharmacopuncture. To promote recovery, we additionally performed needle-embedding therapy to periocular acupoints. Results : Ptosis started to remarkably improve after performing needle-embedding therapy. After 54 days of treatment, ptosis and eye movement impairment of Rt. eye were significantly improved similar to the normal eye. Dizziness was cured in a few days after administration. Conclusions : This case suggests Korean medicine including needle-embedding therapy is effective against oculomotor nerve palsy symptoms especially for ptosis.

• The Journal of the Society of Stroke on Korean Medicine
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• v.18 no.1
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• pp.67-75
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• 2017

■ Objective This is a case report about monocular abducens nerve palsy in a patient with pontine infarction. ■ Method At the time of onset, the patient had eye movement impairment in right eye and diplopia. Brain MRI image showed that there was an infarction in the right pons where the nucleus of abducens nerve is located. There was no obvious improvement in the eye movement before he received Korean medicine treatment. He recieved Korean medicine including acupuncture, electroacupuncture, pharmacoacupuncture and herb medicines for fifty three days. ■ Result After treatment, the movement of right eye was improved to a normal range. The difference in distance from 'center of the pupil' to 'external canthus of the eye' at maximum abducent in both eye changed 0.9cm to 0.1cm at the discharge. In addition, Diplopia was improved at the discharge. ■ Conclusion This case report demonstrated that the Korean medicine treatment is effective to diplopia and eye movement impairment from abducens nerve palsy caused by pontine infarction.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.1045-1053
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• 2021

Objectives: This study investigated the effectiveness of acupuncture and herbal medicine (Gami-banhabakchulchunma-tang) for post-stroke visual impairment. Methods: A 79-year-old male with headache, dizziness, visual field defects, and blurred vision caused by a posterior cerebral infarction was treated with acupuncture and Gami-banhabakchulchunma-tang for three months. We used the Numerical Rating Scale (NRS) for each symptom and measured the patient's eye-movement range. Results: Following treatment, the NRS score for headache decreased from 5 to 0, and for dizziness and blurred vision, it decreased from 5 to 1. The NRS score for visual field defects decreased from 5 to 2. The range of the patient's left and right eye movements both improved, and no adverse side effects were observed during the admission period. Conclusions: Korean medical treatment with acupuncture and herbal medicine (Gami-banhabakchulchunma-tang) could effectively treat post-stoke visual impairment.

• The Journal of Korean Physical Therapy
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• v.14 no.4
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• pp.1-19
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• 2002

The purpose of this study is to identify influence that eye movement have an effect on postural control and balance performance by plegia side of the impaired patients of central nervous system. Subjects are patients with the impairment of central nervous system and experimental and control groups are forty people and thirty people seperatively, Total subjects were selected to seventy persons, but twelve persons of experimental group quit during the experimental periods and eight persons of control group did not measure after exercise. Therefore, twenty eight persons of experimental group and twenty two persons of control group were selected in this study and experimental group peformed eye movement for eight weeks according to the exercise program of this study. The measurement of dependent variable is right static balance, left static balance, bilateral static balance, and bilateral dynamic balance before exercise and after eighth week of exercise, examiner again measured and analyzed the results. The results were as follows: 1. As the result of comparing balance performance ability after test of the experimental and control group with right hemiplegia and control group, all of static balance performance ability of right side (p < 0.01), static balance performance ability of left side (p < 0.01), static balance performance ability of bilateral side(p < 0.01), dynamic balance performance ability of bilateral side(p < 0.05) of experimental group were statistically greater improved than those of the control group. 2. As the result of comparing balance performance ability after test of the experimental and control group with left hemiplegia and control group, all of static balance performance ability of right side (p < 0.01), static balance performance ability of left side (p < 0.01), static balance performance ability of bilateral side(p < 0.05), dynamic balance performance ability of bilateral side(p < 0.05) of experimental group were statistically greater improved than those of the control group.

• Biomolecules & Therapeutics
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• v.26 no.4
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• pp.368-373
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• 2018

Rapid eye movement (REM) sleep has an essential role in the process of learning and memory in the hippocampus. It has been reported that linalool, a major component of Lavandula angustifolia, has antioxidant, anti-inflammatory, and neuroprotective effects, along with other effects. However, the effect of linalool on the cognitive impairment and behavioral alterations that are induced by REM-sleep deprivation has not yet been elucidated. Several studies have reported that REM-sleep deprivation-induced memory deficits provide a well-known model of behavioral alterations. In the present study, we examined whether linalool elicited an anti-stress effect, reversing the behavioral alterations observed following REM-sleep deprivation in mice. Furthermore, we investigated the underlying mechanism of the effect of linalool. Spatial memory and learning memory were assessed through Y maze and passive avoidance tests, respectively, and the forced swimming test was used to evaluate anti-stress activity. The mechanisms through which linalool improves memory loss and behavioral alterations in sleep-deprived mice appeared to be through an increase in the serotonin levels. Linalool significantly ameliorated the spatial and learning memory deficits, and stress activity observed in sleep-deprived animals. Moreover, linalool led to serotonin release, and cortisol level reduction. Our findings suggest that linalool has beneficial effects on the memory loss and behavioral alterations induced by REM-sleep deprivation through the regulation of serotonin levels.

• Journal of Korean Neurosurgical Society
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• v.30 no.1
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• pp.105-109
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• 2001

Lymphangioma is a rare benign developmental vascular tumor that may be found in orbit, skull and elsewhere in head and neck. Few cases of extension of this benign but insidious tumor posteriorly out of the bony orbital cavity have been reported. The patient was 40-year-old man complaining of proptosis of right eye for one month. Physical examination revealed severe right exophthalmus, impairment of eyeball movement in all directions. Visual acuity was much impaired and he could percept only light with right eye. CT and MRI scans showed intraconal and extraconal involvement of ill-defined, heterogenous mass with extension of the tumor posteriorly beyond the orbital cavity involving right frontal and temporal lobe, skull and subcutaneous tissue. The tumor was subtotally removed via orbito-frontal approach without damaging vital neural and orbital component. Then, orbital roof reconstruction and cranioplasty were done with resin. Successful surgical removal of lymphangioma is very difficult due to its severe infiltration to surrounding tissue and tendency to bleed during debulking. We report a rare case of orbital cavernous lymphangioma with intracranial extension treated with surgical decompression, with review of literatures.

• PNF and Movement
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• v.14 no.3
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• pp.237-244
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• 2016

Purpose: This case report examines the influence of proprioceptive neuromuscular facilitation (PNF) combined with a dynamic neuromuscular stabilization approach on balance in patients with cerebellar atrophy. Methods: The target subject of this case report was a 34-year-old woman who was informed of the purpose of this research and voluntarily agreed to participate in it. The case report conformed to research ethics based on the Helsinki Declaration. The target subject was confirmed to have cerebellar atrophy from an unknown cause in 2009 and was diagnosed with slight ataxia. At that time, she could carry out daily activities without physical therapy. On May 19, 2015, she suffered both a subdural hemorrhage (SDH) and subarachnoid hemorrhage (SAH) in a traffic accident. She was urgently moved to the emergency room and managed by nonsurgical treatment, and then, the cerebellar atrophy and ataxia gradually deteriorated. To evaluate the patient's balance capacity before and after intervention, the trunk impairment scale (TIS), trunk impairment scale (OLST) during eye-closing/opening, timed up and go test (TUG), and visual analogue scale (VAS) were conducted. The PNF intervention program was executed for 30 min, four times a week, for three weeks. Results: The TIS and OLST during eye-closing/opening were improved by as much as a point, by 8.15 s and 6.21 s, respectively, after applying the PNF program. TUG and VAS decreased by 1.33 s and 3 points, respectively, after intervention. According to the result, the OLST during eye-closing/opening and VAS improved remarkably in comparison with those before intervention. Conclusion: As the final result of the case report, PNF intervention combined with DNSA more effectively improved the static balance capacity, such as the OLST during eye-closing/opening and VAS, compared to the dynamic balance capacity. In addition, the intervention duration and period of the exercise program are recommended to be more than 1 h a day for four weeks considering the learning ability of a patient with cerebellar atrophy.