• Journal of Sasang Constitutional Medicine
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• v.25 no.3
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• pp.145-157
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• 2013

Objectives This study was aimed to reveal the characteristics of the body shape, face, voice and temperament in Taeyangin. Methods The subjects were recruited from November 2005 to August 2012. Sasang constitutional specialist in each clinics confirmed the Sasang Constitution. Taeyangin (TY) became a standard guidance to be compared with each other Sasang type. Anova test was used in analyzing continuous variables and factor analysis was conducted in temperament questionnaire in advance. Generalized propensity score with age and body mass index (BMI) was used in adjusted model. Significant level was .05 Results 1. The TY body shape were generally smaller than Taeeumin (TE) (p<0.001) and Soyangin (SY) (p<0.05) in crude. The TY body shape were still smaller than TE (p<0.05) and there was no significant difference between TY and SY except rib circumference in males and forehead circumference (p<0.05) in females in adjusted model. 2. The size of face and nose in TY was smaller than in TE and there was different between males and females' TY and others in the characteristics of eye, nose and forehead variables in crude (p<0.05). Most of differences between TY and TE were disappeared in adjusted model. 3. The vocal height and speed of TY was different other types and there was different between males and females' TY in some of frequency change rate in crude (p<0.05). Most of differences between TY and other types were similar before and after adjusted model. 4. The temperament of TY was different with SE before and after adjusted mode 1 (p<0.05). TY males showed difference in expression factor and TY females showed difference in behavior factor compared with TE respectively (p<0.05). Conclusions This study reveals characteristics of body shape, face, voice and character in the TY males females compared with each other type respectively.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.28 no.6
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• pp.499-510
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• 2006

Malignant tumors of the human salivary glands may arise from major or minor salivary glands. Adenoid cystic carcinoma (ACC) is the second most common malignant neoplasm in the salivary glands. ACC is occasionally highly aggressive tumor that readily invades adjacent tissues and metastasize to distant organs at early stages of the disease. Although ACC tends to grow slowly, treatment outcome may be poor due to wide local infiltration, perineural or intraneural spread and a propensity for hematogenous metastasis. Therefore, knowledge of cellular and molecular characteristics that influence the growth, survival and metastasis of tumor cells, is important for new treatment strategies of salivary ACC. I determined expressions of epiderma growth factor (EGF)-signaling molecules using surgical specimens of human ACCs. Protein expressions of EGF, transforming growth $factor(TGF)-{\alpha}$, EGF receptor (EGFR), phosphorylated EGFR (pEGFR), and human EGF receptor (HER)-2 were assessed in 18 cases of salivary ACC by immunohistochemical staining. Adjacent normal salivary tissues and mucosal tissues, uninvolved by the malignant tumor, served as internal controls. Most of the tumors, especially ACC with a tubulocribriform pattern, were positive for EGF signaling molecules. The overall percentages of the 18 specimens expressing EGF, $TGF-{\alpha}$, EGFR, pEGFR, and HER2 were 50, 89, 61, 61 and 83% respectively. Moreover, tumor-associated endothelial cells and infiltrating immune-related cells in the stroma of ACC, also expressed these biomarkers. Taken together, EGF-signaling molecules are actively expressed in salivary ACC. Therefore, we suggest that these biomarkers can be molecular targets for new treatment strategies of salivary tumors.