• Asian Journal of Atmospheric Environment
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• v.4 no.3
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• pp.157-165
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• 2010

The purpose of this study is to investigate allergic diseases related to allergy caused by the exposure to indoor and outdoor sources of air pollution in primary schools. The symptoms questionnaire of allergic diseases based on the International Study of Asthma and Allergies in Childhood (ISAAC) was completed by the participants. The past and present status of asthma, allergic rhinitis, eczema, and allergic conjunctivitis were investigated by providing a questionnaire to all the participating children. Questionnaires were sent to a total of 61,350 children from 438 primary schools. A total of 40,522 children responded to the questionnaire, which represents a 66.1% return rate. Volatile Organic Compounds (VOCs), $\underline{A}$ldehydes, and Particulate Matter ($PM_{10}$) were measured and analyzed from October to December of 2006, in 82 primary schools. The final study population comprised 35,168 children with complete data which excluded incomplete questionnaire responded by 5,354 children. Based on the survey, the level of indoor air contamination did not appear to be high, but 27.2% of the schools evaluated had exceeded the $PM_{10}$ level specified by the school health guidelines ($100\;{\mu}g/m^3$). The overall mean concentration of formaldehyde was $22.07\;{\mu}g/m^3$ and 1.0% of schools (1 school) exceeded the $100\;{\mu}g/m^3$. Statistically significant relationships have been observed between indoor air quality and prevalence rate of allergic rhinitis and conjunctivitis of primary schools in Korea.

• Journal of the Korean Graphic Arts Communication Society
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• v.27 no.1
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• pp.1-14
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• 2009

The color reproduction of digital still camera does not, in general, match those of the final output device. Because color gamut of these devices is different, it is therefore necessary to take account of a way to match. The way uses the optimized profile to output device an image. This paper proposed a way to create the input profile of digital still camera for standardization soft proofing process. The results of proposed way showed that for input profiles equivalent, good results relatively. In this paper, an experiment was done where the illumination sources used as the standard illumination 5200K and illuminated at a $45^{\circ}$ angle in the best illumination efficiently. The white balance was in mode 'custom' : aperture F11, exposure time 1/60s, ISO50, focal length 80mm. The images were exported and saved as 16bit RGB TIFF(AdobeRGB, sRGB, ProphotoRGB) images. To do the test, the RGB values of the RGB TIFF images are processed through the ICC input profile to arrive at processed $CIEL^*a^*b^*$ values. A profiling tool such as ProfileMaker 5.0 and Monacoprofile 4.8 are used to do this. The processed $CIEL^*a^*b^*$ values are compared to the reference $CIEL^*a^*b^*$ values and these two values are used to calculate a ${\Delta}E{^*}_{ab}$.

• Safety and Health at Work
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• v.6 no.3
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• pp.159-173
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• 2015

The hand coordinate systems for measuring vibration exposures and biodynamic responses have been standardized, but they are not actually used in many studies. This contradicts the purpose of the standardization. The objectives of this study were to identify the major sources of this problem, and to help define or identify better coordinate systems for the standardization. This study systematically reviewed the principles and definition methods, and evaluated typical hand coordinate systems. This study confirms that, as accelerometers remain the major technology for vibration measurement, it is reasonable to standardize two types of coordinate systems: a tool-based basicentric (BC) system and an anatomically based biodynamic (BD) system. However, these coordinate systems are not well defined in the current standard. Definition of the standard BC system is confusing, and it can be interpreted differently; as a result, it has been inconsistently applied in various standards and studies. The standard hand BD system is defined using the orientation of the third metacarpal bone. It is neither convenient nor defined based on important biological or biodynamic features. This explains why it is rarely used in practice. To resolve these inconsistencies and deficiencies, we proposed a revised method for defining the realistic handle BC system and an alternative method for defining the hand BD system. A fingertip-based BD system for measuring the principal grip force is also proposed based on an important feature of the grip force confirmed in this study.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2939-2946
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• 2015

Many of the anti-cancer agents currently used have an origin in natural sources including plants. Aloe vera is one such plant being studied extensively for its diverse health benefits, including cancer prevention. In this study, the cytotoxic potential of Aloe vera crude extract (ACE) alone or in combination with cisplatin in human breast (MCF-7) and cervical (HeLa) cancer cells was studied by cell viability assay, nuclear morphological examination and cell cycle analysis. Effects were correlated with modulation of expression of genes involved in cell cycle regulation, apoptosis and drug metabolism by RT-PCR. Exposure of cells to ACE resulted in considerable loss of cell viability in a dose- and time-dependent fashion, which was found to be mediated by through the apoptotic pathway as evidenced by changes in the nuclear morphology and the distribution of cells in the different phases of the cell cycle. Interestingly, ACE did not have any significant cytotoxicity towards normal cells, thus placing it in the category of safe chemopreventive agent. Further, the effects were correlated with the downregulation of cyclin D1, CYP 1A1, CYP 1A2 and increased expression of bax and p21 in MCF-7 and HeLa cells. In addition, low dose combination of ACE and cisplatin showed a combination index less than 1, indicating synergistic growth inhibition compared to the agents applied individually. In conclusion, these results signify that Aloe vera may be an effective anti-neoplastic agent to inhibit cancer cell growth and increase the therapeutic efficacy of conventional drugs like cispolatin. Thus promoting the development of plant-derived therapeutic agents appears warranted for novel cancer treatment strategies.

• Survey Research
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• v.11 no.2
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• pp.29-44
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• 2010

The aim of this study was to determine principal non-acoustical factors for noise annoyance in the vicinity of Kimpo Airport in Seoul, Korea. Noise annoyance was estimated using self-reported annoyance scale. We have conducted a social survey aiming to identify the main sound sources, evaluate the annoyance and analyse the main effects of noise on people. Acoustical and non-acoustical variables are expected to greatly affect annoyance responses. This study divided acoustical variables into aircraft, road traffic and neighboring noises, and non-acoustical variables into demographic, situational and attitudinal variables. The study performed multiple regression analysis to determine the influences each variable has on annoyance responses. Acoustical variables affect noise annoyance to aircraft and neighboring noise except road traffic noise. For road traffic and neighboring noise annoyance was affected by non-acoustical variable, insulation by housing type. For aircraft noise, main noise source of this area, annoyance was affected by acoustical variable and some non-acoustical variables, mainly exposure time.

• Journal of Environmental Health Sciences
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• v.33 no.6
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• pp.479-487
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• 2007

[ $PM_{2.5}$ ], particulate matter less than 2.5 um in a diameter, can penetrate deeply into the lungs. Exposure to $PM_{2.5}$ has been associated with increased hospital visits for respiratory aliments as well as increase mortality. $PM_{2.5}$ is a byproduct of combustion processes and as such has a complex composition including a variety of metallic elements, inorganic and organic compounds as well as biogenic materials (microorganisms, proteins, etc). In this study, the average concentrations of fine particulates $PM_{2.5}$ have been measured simultaneously in Asan and Seoul, Korea, by using particulate matter portable sampler from September 2001 to August 2002. Sample collection filters were analyzed by ICP-OES to determine the concentrations of metallic elements (As, Ni, Fe, Cr, Cd, Cu, Pb, Zn, Si). Annual mean $PM_{2.5}$ concentrations in Asan and Seoul were 37.70 and $45.83\;{\mu}g/m^3$, respectively. The highest concentrations of $PM_{2.5}$ were found in spring season in both cities and the concentrations of measured metallic elements except As in Asan were higher than those in Seoul, suggesting that yellow dust in spring could affect $PM_{2.5}$ concentrations in Asan rather than Seoul. The correlation coefficients of Pb and Zn were 0.343 for Asan and 0.813 for Seoul during non-yellow dust condition, suggesting that Pb and Zn were influenced with the same sources. The correlation coefficients between Si and Fe in the fine particulate mode were 0.999 (Asan) and 0.998 (Seoul) during yellow dust condition. It was suggested that these two elements were impacted by soil-related transport from China during the yellow dust storm condition.

• BMB Reports
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• v.53 no.10
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• pp.539-544
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• 2020

Skin aging appears to be the result of overlapping intrinsic (including genetic and hormonal factors) and extrinsic (external environment including chronic light exposure, chemicals, and toxins) processes. These factors cause decreases in the synthesis of collagen type I and elastin in fibroblasts and increases in the melanin in melanocytes. Collagen Type I is the most abundant type of collagen and is a major structural protein in human body tissues. In previous studies, many products containing collagen derived from land and marine animals as well as other sources have been used for a wide range of purposes in cosmetics and food. However, to our knowledge, the effects of human collagen-derived peptides on improvements in skin condition have not been investigated. Here we isolate and identify the domain of a human COL1A2-derived protein which promotes fibroblast cell proliferation and collagen type I synthesis. This human COL 1A2-derived peptide enhances wound healing and elastin production. Finally, the human collagen alpha-2 type I-derived peptide (SMM) ameliorates collagen type I synthesis, cell proliferation, cell migration, and elastin synthesis, supporting a significant anti-wrinkle effect. Collectively, these results demonstrate that human collagen alpha-2 type I-derived peptides is practically accessible in both cosmetics and food, with the goal of improving skin condition.

• The Korean Journal of Community Living Science
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• v.15 no.1
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• pp.17-26
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• 2004

Not much is known about Korean clothes from past centuries. Fortunately, we are able to make some inferences based on various sources of data other than the actual clothes themselves. Historical records such as Kim Hong-do's Pungsokhwa Pieces, well known to us, vividly depict features of the costume and the lifestyle of his time along with contemporary Korean humor and atmosphere. Kim Hong-do is the artist who, having accomplished pictorial refinement, recognized social change and took this into his artistic world late in the 18th century. The ruling classes, in contrast, tended to adhere to anachronistic medieval philosophies in a gradually changing society. In this study, Kim Hong-do's Pungsokhwachop, Treasure No. 527, preserved in the National Museum of Korea, was viewed from a new perspective, and it was discovered to have assorted the costume and culture of ordinary people according to their life styles. Fourteen of the pieces depicted how common citizens made their living, three described love affairs, five depicted people at play, md the rest showed elements of education, wedding ceremonies, and shamanism, respectively. Various types of clothing were observed reflecting the life styles of ordinary people, and a somewhat bold exposure of body was noticed in women's fashion in the late Chosun Dynasty. They chose clothing as they pleased to fit their jobs and functions, which produced elegant self-regulation and creativity based on practical beauty. A hat - yet to be found as a relic - appeared in Blacksmith's Workshop, and revealed the changing social customs of the late Chosun Dynasty in the 18th century. It is hoped that the results of this study will serve as a valuable reference point for the globalization of Korean clothes.

• Journal of the Korean Society for Library and Information Science
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• v.44 no.4
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• pp.33-59
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• 2010

Library 2.0 advocates a socially rich, multimedia enabled, user originated and communally innovative environment that poses significant opportunities for the libraries to evolve and make themselves even more relevant and significant for her users. This paper presents a case study of the National Library Board of Singapore, in playing a vital role to facilitate the realisation of a long-term key national program, The Singapore Memory (SM) Project. SM embraces the attributes of the Library 2.0 environment to enable the nation's memory to be collected, organised, preserved, discovered, researched, augmented and created. The output of is an evolving collection of knowledge assets on Singapore along a Singapore Memory Content Continuum of existing content that is steadily augmented with new content. The content will be collected across all formats, in any language, from Singaporeans and non-Singaporeans, from any institution and agency, from Singapore and abroad, and from official and unofficial sources. The utopian scenario of SM Project is that any person, community, group or institution who has ever experienced Singapore in any way or has any material on Singapore will engage actively in the contribution, discovery and creation of content for the project, and thus become advocates to further encourage and catalyse more contribution, discovery and creation. The paper outlines the key approaches, concepts and ideas for the project. An important element is the proliferation, exposure and accessibility of the rich contents envisaged in the project. The SM proliferation plan along with examples of how two existing resources, namely, the Singapore Infopedia, a database of articles on Singapore's history, culture, people and events 4 and NewspaperSG, an online resource of current and historic Singapore and Malayan newspapers, have been designed are presented to demonstrate how content can be exposed, searched and discovered.

• Journal of The Korean Society of Clinical Toxicology
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• v.8 no.1
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• pp.30-36
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• 2010

Purpose: The purpose of this study is to analyze the clinical characteristics of anaphylaxis and anaphylactic shock caused by bee venom. Methods: We retrospectively collected the data of the patients who experienced anaphylaxis caused by natural bee sting or acupuncture using bee venom from January 1999 to December 2008. Seventy subjects were divided into the shock and non-shock groups. The clinical characteristics, sources of bee venom, treatments and outcomes were compared between the two groups. Results: The mean age of the subjects was $45.5{\pm}16.3$ years old and the number of males was 44 (62.9%). There were 25 patients in the shock group and 45 in the non-shock group. The age was older (p=0.001) and females (p=0.003) were more frequent in the shock group. Transportation to the hospital via ambulance was more frequent in the shock group (p<0.001). No difference was found in species of bee between the two groups. The cephalic area, including the face, was the most common area of bee venom in both groups. Anaphylaxis caused by bee sting commonly occurred between July and October. Cutaneous and respiratory symptoms were the most frequent symptoms related to anaphylaxis. Cardiovascular and neurologic symptoms were more frequent in the shock group. The amount of intravenously administered fluid and subcutaneous injection of epinephrine were much more in the shock group than that in the non-shock group. Conclusion: Older age was the factors related to anaphylactic shock caused by bee venom. Further validation is needed to evaluate the gender factor associated with shock.