• 제목/요약/키워드: exposure characteristics

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심장 전기생리학 검사 시 조건 변화에 따른 환자 피폭 선량 평가 (Evaluation of Patient Exposure Dose during Cardiac Electrophysiology Study under Various Conditions)

  • 고성빈;안성민
    • 대한방사선기술학회지:방사선기술과학
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    • 제46권6호
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    • pp.501-508
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    • 2023
  • This study used a adult absorption dose phantom (CIRS model 701-G, USA) made of human equivalent material and the vascular imaging equipment Allura Xper FD 20 (Philips, Netherlands). Optically stimulated luminescent dosimeters (OSLD) were inserted into the anatomical positions corresponding to each organ, and the exposure dose was measured. Dose area product (DAP) and air kerma (AK) measured by the dose meter in the equipment were compared. Continuous imaging was performed at two angles for a total of 20 minutes, with a frame per seconds of 3.75 and 7.5 fps and an FOV of 42 cm, 37 cm, and 31 cm, respectively, under the conditions of fluoflavor I, II, and III, each selected for 5 repetitions. This study was found that selecting a lower fps was the most effective way to reduce patient exposure dose, and adjusting the fluoflavor was a good alternative method for reducing patient exposure dose at high fps. Therefore the method of condition change with the greatest dose reduction effect is to set the minimum FPS and can reduce patient exposure dose according to geometric conditions and fluoflavor characteristics.

화학물질 관리 연구-1. 산업안전보건법상 관리 화학물질의 특성과 노출기준 비교 (Study on the Chemical Management - 1. Chemical Characteristics and Occupational Exposure Limits under Occupational Safety and Health Act of Korea)

  • 박지훈;함승헌;김선주;이권섭;하권철;박동욱;윤충식
    • 한국산업보건학회지
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    • 제25권1호
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    • pp.45-57
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    • 2015
  • Objectives: This study aims to compare the physicochemical characteristics, toxicological data with Occupational Exposure Limits (OELs) of chemicals under the Occupational Safety and Health Act(OSHA) regulated by the Ministry of Employment and Labor of Korea. Methods: Information on chemicals which have OELs on physicochemical characteristics and toxicological data was collected using Material Safety Data Sheet(MSDS) from Korea Occupational Safety and Health Agency(KOSHA) and the Korea Information System for Chemical Safety Management(KISChem) in 2014. Statistical analyses including correlation and simple regression were performed to compare the OELs with chemical characteristics including molecular weight, boiling point, odor threshold, vapor pressure, vapor density, solubility and octanol-water partition coefficient(OWPC) and toxicological data such as median lethal dose($LD_{50}$) and median lethal concentration($LC_{50}$). Results: A total of 656 chemicals have OELs under OSHA in Korea. The numbers of chemicals which have eight-hour time weighted average(TWA) and short term exposure limits(STEL) are 618 and 190, respectively. TWA was significantly correlated with boiling point and STEL was only correlated with vapor pressure among physicochemical characteristics. Solubility and OWPC between "skin" and "no skin" substances which indicate skin penetration were not significantly different. Both $LD_{50}$ and $LC_{50}$ were correlated with TWA, while the $LC_{50}$ was not with STEL. As health indicators, health rating and Emergency Response Planning Guidelines(ERPG) rating as recommended by the National Fire Protection Association(NFPA) and American Industrial Hygiene Association(AIHA) were associated with OELs and reflect the chemical hazards. Conclusions: We found relationships between OEL and chemical information including physicochemical characteristics and toxicological data. The study has an important meaning for understanding present regulatory OELs.

지게차 운전원의 블랙카본(black carbon, BC) 노출에 영향을 미치는 직업적 요인 (Occupational Factors Influencing the Forklift Operators' Exposure to Black Carbon)

  • 이혜민;이승희;류승훈;박지훈;박동욱
    • 한국산업보건학회지
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    • 제27권4호
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    • pp.313-323
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    • 2017
  • Objectives: This study aimed to assess exposure to black carbon(BC) among forklift operators and to identify environmental and occupational factors influencing their BC exposure. Methods: We studied a total of 23 forklift operators from six workplaces manufacturing paper boxes. A daily BC exposure assessment was conducted during working hours from January to April 2017. A micro-aethalometer was used to monitor daily BC exposure, and information on work activities was also obtained through a time-activity diary(TAD) and interviews. BC exposure records were classified into four categories influencing BC exposure level: working environment, workplace, forklift operation, and job characteristics. Analysis of variance(ANOVA) was used to compare average BC exposure levels among the four categories and the relationships between potential factors and BC exposure were analyzed using a multiple linear regression model. Results: The operators' daily exposure was $12.9{\mu}g/m^3$(N=9,148, $GM=7.5{\mu}g/m^3$) with a range: $0.001-811.4{\mu}g/m^3$. The operators were exposed to significantly higher levels when they operate a forklift in a room ${\leq}20,000m^3$($AM=12.3{\mu}g/m^3$), in indoor workplaces($AM=16.3{\mu}g/m^3$), when they operate a forklift manufactured before 2006 ($AM=13.2{\mu}g/m^3$), a forklift with a loading limit of four-tons($AM=27.1{\mu}g/m^3$), with a roll and bale type clamp($AM=17.1{\mu}g/m^3$), and with no particulate filter($AM=15.7{\mu}g/m^3$). Conclusions: Occupational factors including temperature, smoking, season, daytime, room volume($m^3$), location of operating, and manufacturing era and model of forklift influenced the BC exposure of forklift operators. The results of this study can be used to minimize the BC exposure of forklift operators.

음용수의 섭취량 및 다경로 노출평가를 위한 노출변수 조사연구 (Daily Water Intake and Exposure Parameters Related to the Multi-route Exposure in Drinking Water)

  • 정용;신동천;박성은;최시내;박선미
    • Environmental Analysis Health and Toxicology
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    • 제11권1_2호
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    • pp.19-29
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    • 1996
  • Human exposure to volatile compounds in tap water can occur from inhalation and dermal absorption as well as direct ingestion. The relative contribution to total human exposure from these pathways has been considered to be important especially for VOC's (volatile organic compounds). In an attempt to reduce the uncertainty of the risk assessment, it has been suggested that the exposure assessment process could be significantly improved by adopting Monte-Carlo simulation. However, there is no actual data in Korea for each exposure parameter to determine the level of exposure, and the distributional pattern. Therefore, we surveyed water use patterns and behavior related to multi-route exposure to VOC's in household tap water in Korea, and compared these values to the those in western countries. In the first survey, we calculated daily water intake using data from a sample of 1322 persons of several cities in Korea. In the second survey, we obtained questionnaire data on exposure time for showering, bathing and household activities, and tap water intake from 851households in Korea. In the last survey, we measured the exposure parameters (exposure time, water use rate etc.) related to showers, baths, toilets, dish washing, washing and cooking, and tap water intake was surveyed. Also, the subjects were measured their body weight, height and tidal volume, etc. A diary, a flow meter and a measuring cup were used to measure these values as precisely as possible. Average daily water intake was ranged 0.79-1.71 L/day for adults in three surveys. Tap water intake measured by log-sheet during one week in third survey was 1.26 (average), 1.98 L/day (90 percentlie), respectively. These results were comparable with results from EPA (1.4, 2L/day). The average amount of water used by housewives in the third survey was 515.0 $\pm$ 564.6L/day. In usual activity, the amount of water used in the bathroom, the laundry and the kitchen was 140.0 $\pm$ 538.9, 148.0 $\pm$ 174.5, 229.3 $\pm$ 205.4 L/day, respectively. Exposure parameters such as water intake rate, exposure duration, body weight, inhalation rates in surveyed data of Korean people differed from those published from western countries. This could be attributed to variations in lifestyle, dietary habits and physiological characteristics.

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모의 실험주택 모니터링 결과를 활용한 실내공기 및 바닥먼지 중 Di(2-ethyl-hexyl) phthalate (DEHP)의 이론적 총량 비율 산출 (Calculation of the Theoretical Total Amount Ratio of Di(2-ethyl-hexyl) Phthalate in Indoor Air and Floor Dust in a Test House)

  • 천사호;이가원;김승중;정승표;강다영;김기태
    • 한국환경보건학회지
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    • 제49권6호
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    • pp.324-333
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    • 2023
  • Background: Human exposure to phthalates in indoor environments occurs via dermal absorption, oral ingestion of indoor dust, and inhalation of indoor air. However, systematic studies to investigate the exposure rate to phthalates among the three exposure routes in indoor environments are currently limited. Objectives: A theoretical exposure ratio between inhalation and oral exposure was calculated based on the total amount of di(2-ethyl-hexyl) phthalate (DEHP) emitted into indoor air and deposited into floor dust in a test house. Methods: Flooring and wallpaper containing DEHP were installed in a test house and the concentration of DEHP in both indoor air and floor dust were monitored for five months. Based on the measured DEHP concentrations, the theoretical total amount ratio of DEHP that could be exposed through inhalation and oral ingestion was calculated. Results: Considering the period of operation in the test house, the theoretical total amount of DEHP through inhalation and oral ingestion exposures in the entire test house space was calculated to be 0.014 mg and 5.5 mg, respectively. The exposure ratio of the two routes between inhalation and oral exposure corresponding to the total DEHP amount in flooring and wallpaper was 6.0×10-7% and 2.3×10-4%, indicating that theoretical oral exposure to DEHP is approximately 380 times higher than inhalation. Conclusions: Monitoring results from a test house has shown that oral exposure is the main exposure route for DEHP in indoor environments. The experimental design employed in this study and theoretical exposure ratio obtained can be applied to investigate actual exposure to DEHP and to determine the exposure characteristics of various types of semi-volatile organic compounds.

교통소음의 노출시간에 따른 주관반응 평가시 음원 및 전달 특성의 효과 분석 (Effect of the Properties of Sound Source and Transmission for the Evaluation of Subjective Response by the Exposure Time of Transportation Noise)

  • 김선우;김원식;송국곤;강종구;박현구
    • 한국소음진동공학회논문집
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    • 제22권3호
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    • pp.264-274
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    • 2012
  • Evaluation on the environmental noise is carried out by surveying subjective response of residents with physical measurement of noise during long period in field. Particularly field survey is used to make regulations from the analysis on how many people are annoyed for specific noise level, and laboratory test used to analyze the relationship between physical parameters of noise and subjective responses. In the laboratory controlling the variables is easy but the results could be biased because the condition in room would be different with field. Most of all noise exposure time is considered to be different with real situation, and this study aimed to evaluate the subjective response by exposure time of transportation noise, by applying three kinds of variable how much they give effects on the annoyance as the exposure time is operating condition, windows type and sound level. As a result there was somewhat difference between operating type and annoyance, which is caused by the sound characteristics operated in different condition. However the window type didn't give much effect to the annoyance as much as sound type. This means that the subjective response could give similar result by exposure time even for different window types. Most of all, the main factor affecting subjective response is considered to be the sound level and the exposure time.

여대생의 미디어 노출과 관여도가 객체화된 신체의식 및 외모관리행동에 미치는 영향 (The Effects of Media Exposure and Involvement of Female University Students on Objectified Body Consciousness and Appearance Management Behaviors)

  • 이미숙
    • 한국의상디자인학회지
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    • 제19권4호
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    • pp.59-73
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    • 2017
  • This study examined the effects of media exposure and involvement on objectified body consciousness and appearance management behaviors. The subjects were 325 female university students in Daejeon and Chungnam Province. The research method was a survey, and the questionnaire was composed of media exposure and involvement, objectified body consciousness, appearance management behaviors, and subjects' demographic characteristics. The data were analyzed by descriptive statistics, Cronbach's ${\alpha}$, factor analysis, and regression analysis using SPSS program. The results were as follows. First, female university students used mass media for about 3.76 hours a day and showed a high level of media involvement. Second, three factors (body surveillance, body shame, and appearance control belief) emerged regarding objectified body consciousness with female university students showing a high level of objectified body consciousness. Third, six factors (make-up, plastic surgery, weight control, fashion, hair, and skin care) emerged regarding appearance management behaviors with female university students showing high intention to perform various appearance management behaviors. Fourth, media exposure and involvement had important effects on objectified body consciousness and appearance management behaviors, and media involvement was a more important variable than media exposure. Fifth, objectified body consciousness had important effects on appearance management behaviors. Body shame had more important effects on skin care, weight control, and plastic surgery behaviors, while body surveillance had more important effects on fashion, make-up, and hair management behaviors than other objectified consciousness factors. The implication of this study was that media involvement is a more important variable affecting objectified body consciousness and appearance management behaviors than media exposure, and among objectified body consciousness dimensions, body shame has important effects on more active appearance management behaviors like weight control and plastic surgery behaviors.

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VOCs의 위해성 평가를 위한 노출분석 방법 연구 (The Development of Exposure Assessment Tools for Risk Assessment of Volatile Organic Compounds)

  • 조성준;신동천;정용;이덕희
    • Environmental Analysis Health and Toxicology
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    • 제17권2호
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    • pp.147-160
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    • 2002
  • Volatile organic compounds (VOCs) are an important public health issue in Korea and many important questions remain to be addressed with respect to assessing exposure to these compounds. Because they are ubiquitous and highly volatile, special techniques must be applied in their analytic determination Valid Personal exposure assessment methods are needed to evaluate exposure frequency, duration and intensity, as well as their relationship to personal exposure characteristics. Biological monitoring is also important since it may contribute significantly in risk assessment by allowing the estimation of effective absorbed doses. This study was on ducted to establish the environmental measurement, personal dosimetry and biological monitoring methods for VOCs. These methods are needed to compare blood, urinary and exhalation breath VOC levels and to provide tools for risk assessment of VOC exposure. Passive monitors (badge type) and a active samplers (trap) for the VOCs collection were used for air sampling. Methods development included determining the minimum detectable amounts of VOCs in each media, as well as evaluating collection methods and developing analytical procedures. Method reliability was assessed by determining breakthrough volumes and comparing results between laboratories and with other methods. A total capacity of trap used in this study was 60ι. Although variable by compound, the average breakthrough was 20%. Also, there was no loss of compounds in trap even if keep for 45 day in -7$0^{\circ}C$. The recovery of active and passive methods was 69% ~ 126% and method detection limit was 0.24 $\mu\textrm{g}$/trap and 0.07 $\mu\textrm{g}$/badge. There was no statistical difference (P > 0.05) between active and passive methods.

임부의 약물 노출 관련 등록지침 개발 연구 (Development of Drug Exposure Registries on Pregnant Women)

  • 김수희;노혜진;지은희;윤정현;김경임;신완균;오정미
    • 한국임상약학회지
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    • 제20권2호
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    • pp.114-119
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    • 2010
  • Objectives: We developed a registry guidance to provide a standard for data collection, analysis and methodical management of information on the influence of drug exposure on pregnant women and fetus. Methods: We surveyed guidances and regulations of clinical trials and the pharmaceutical affairs law, compared them with Pregnancy Exposure Registry of other countries and in addition, investigated related references. We found the flaws of the present registry and supplemented it based on better results from other countries. Results: We developed a concrete and detailed report that included pregnancy drug exposure cases necessary for close monitoring, types and characteristics of data on pregnancy drug exposure, the requirements of registry data, and essential items needed to be researched. Conclusions: Information on pregnancy drug exposure in Korea can be effectively collected by using this report which provides a comprehensive assess to drug's influence on pregnant women and fetus, and in addition, accurate information about safety and effectiveness of drug use in pregnant women and fetus can be obtained by sharing data globally and managing it synthetically and systematically.