• Title/Summary/Keyword: experimental group

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THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF MINOCYCLINE-LOADED POLYCAPROLACTONE STRIP ON PERIODONTAL DISEASE (치주질환치료에서 국소약물 송달제재의 임상 및 세균학적 효과)

  • Choi, Sung-Jae;Lee, Man-Sup;Kwon, Young-Huk
    • Journal of Periodontal and Implant Science
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    • v.23 no.1
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    • pp.170-182
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    • 1993
  • The purpose of this study was to evaluate the clinical and microbiological effects of minocycline-loaded polycaprolactone strip on periodontal disease. Ten patients with probing depth (deeper than 5mm) were tested. Of the two periodontal pockets selected from each patient, one randomly selected pocket was treated by the insertion of 30% minocycline-loaded polycaprolactone sttip as the experimental group and the other with a minocycline-free polycaprolactone strip as the control group. All groups were examined by clinical and microbiological methods. 1. Plaque index scores, gingival index scores and sulcular bleeding index scores in both group were significantly reduced from the baseline to 2 weeks. Plaque index scores of experimental group and sulcular bleeding index scores of control group tended to be progressively reduced in all experimental periods. 2. Probing depth amounts in both group were significantly reduced from 4 weeks to 8 weeks. 3. Attachment loss amounts in both group shows no singnificant differences in time. Attachment loss amounts in experimental group tended to be less than those in control group. 4. The number of cocci in both groups were significantly increased in all experimental periods, but that of the non-motile rods were significantly reduced from 2 weeks in experimental group, and from 4 weeks in control group, that of the motile rods were reduced from 4 weeks in experimental group and from 1 week in control group. The number of spirochetes were reduced from I week during all experimental period in experimental group, but there was no changes in control group.

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Effects of Kwakhyangjungkisangamibang Extract on the Adipose Tissues Induced by a High Fat Diet in Rats (곽향정기산가미방(藿香正氣散加味方)이 고지방식이(高脂肪食餌)로 유식(誘導)된 흰쥐의 체지방에 미치는 영향(影響))

  • Lee, Jin-Yong;Lee, Hoon
    • The Journal of Pediatrics of Korean Medicine
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    • v.21 no.2
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    • pp.153-167
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    • 2007
  • Objetives This experimental study is designed to investigate the effects of kwakhyangjungkisangamibang extract on the changes of adipose tissues, serum insulin and leptin levels in rats induced by a high fat diet. The leptin has been proposed to be involved in the role of food intake and energy expenditure. Methods During the 8 weeks of experimental period, male Sprague-Dawley rats were fed on the 2 different diets: the normal diet AIN-76A and high fat(beef tallow) diet ad libitum, of which 40% of the calories intake was fat. 9 rats in the control and high fat diet group were killed for the baseline experiment at 4 weeks of age. The high fat diet group was divided into three groups: control group, experimental group I(high fat diet plus kwakhyangjungkisangamibang extract), and experimental group II(high fat diet plus mahuang). The body weight, hypodermal fat tissue, serum lipid profile, insulin and leptin levels were measured after the administration of the high fat diet and extract. Results 1. The body weight was decreased in experimental group II, but there was not a significance difference compared to the control group. 2. The peritoneal, visceral, and hypodermal adipose tissue was decreased in experimental group I, but there was not a significance difference compared to the control group. 3. The lipid profile was decreased in experimental group I, but not in group II. 4. The insulin concentration was increased in experimental group I and II, but there was not a significance difference compared to the control group. 5. The leptin level was increased significantly in experimental group I(p<0.05) and II(p<0.01) compared to the control group. Conclusion The results of this study indicate that kwakhyangjungkisangamibang has an effect on the regulation of obesity.

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Experimental Study for Construction of Mouth Care in Chemotherapy Patients (화학요법을 받는 암환자의 구강간호전략을 위한 연구)

  • 변영순;김애경
    • Journal of Korean Academy of Nursing
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    • v.26 no.2
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    • pp.428-442
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    • 1996
  • Stomatitis is a common toxicity associated with the administration of certain cancer chemotherapeutic agents used in the treatment of malignant tumors. It represents one of the most distressing side effects of cancer chemotherapy and can interfere with the patient's ability to eat, be the cause of much pain and discomfort, and require the use of potent analgesics. The situation also creates favorable conditions for local infection which may lead to septicemia. Several authors have identified the need to establish protocols for the control and treatment of the oral discomfort associated with oral mucositis as a result of chemotherapy. Thus this study attempted to development of oral care protocol for chemotherapy patients. The effects of the mouth care using sterile normal saline, nystatine solution on oral stomatitis were investigated in 30 patients on chemotherapy. The subsect were divided into three groups : control group : not gargling experimental group A : normal saline gargling (4 times a day) experimental group B : nystatine solution gargling(4 times a day) The Oral Assessment Guide (OAG) was used to assess oral status three times(once in the prechemotherapy period, on 5th, 10th day of post chemotherapy) Oral culture was used to assess oral infection on 5th day of postchemotherapy. Data was analyzed on SAS program which used repeated ANOVA, t-test, X/sup²test. The results are as follows : 1. The incidence of stomatitis was higher in the control group and experimental group A than in experimental group B.(X/sup²=0.002 P=0.001). The grade of stomatitis(mean of total score) for patients in the experimental group B were significantly lower than in the experimental group A F=1.96 P=0.0024). In incidence of tongue change, control group, experimental group B were significantly higher than experimental group B(F=6.84 P=0.0039). In control group and experimental group A. oral infection due to pathogenic bacteria were identified. In conclusion, mouth care with nystatine solution four times a day could reduce the incidence of stomatitis and secondary oral infection due to stomatitis. Thus active mouth care protocol which used to nystatine solution gargling need to prevention of stomatitis in chemotherapy patients.

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A study on simplified Textile testing apparatus for teaching high school students (중고등학교 피복재료 학습효과를 높이기 위한 시험장치 개발에 관한 연구)

  • 장경연
    • Journal of the Korean Home Economics Association
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    • v.26 no.2
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    • pp.69-79
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    • 1988
  • This study was to increase the experimental learning effect of textile materials in middle and high school. To this study, three kinds of simply devised apparatus were used for warmth retaining test, air permeability test and static electricity test. Two classes were chosen in a girls' high school comparing learning effect and classified the theoretical learning group and the experimental learning group. In the experimental group, a teaching plan to teach the properties of textile materials was made to use these apparatuses. The results were. 1. In the interest on the unit either the theoretical learning group or the experimental learning group were not different significantly. 2. In the items facilitation of motivation, unsatisfied desires and prevention of failure, effect of transfer and development of inquiry power, both groups were significant. 3. For the purpose of comparing the learning effect, two groups were examined for determining the level of understanding after teaching properties of textile materials. The mean value of the experimental learning group was higher than that of the theoretical learning group. The experimental learning group had more higher markers(over the point of 90) than the theoretical learning group.

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An Effect of Aerobic Exercise on Blood Pressure, Pulse Rate Body Fat, Body Weight, Symptoms of Stress Response -With special reference to the adult woman- (에어로빅 훈련이 체지방, 체중, 혈압, 심박수 및 스트레스 반응에 미치는 영향)

  • Kim, Young-Hee
    • Research in Community and Public Health Nursing
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    • v.6 no.1
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    • pp.98-113
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    • 1995
  • The purpose of this study were two fold : first, to determine the effect of aerobic exercise on BP, pulse rate, body fat, body weight, symptoms of sterss response: and secondly, to apply the aerobic exercise on nursing practice in the healthy or ill subjects. In an attempt to investigate the physiological and psychological effect of exercise, a quasi -experiment, non-equivalent control group pre-test & post-test design was planned. Experiments were carried out from July 4, through August 30, 1994 with 37 subjects conveniently sampled from K & Y sports center located in Taejon. The 37 research subjects were assigned to experimental(16 subjects) and control(21 subjects) groups. Aerobic exercise was carried out for experimental group from three times to five times a week for 6 weeks in aerobic center. Data were analyzed with t-test, mean, per centage of change using SAS program. Results were obtained as follows: 1) Systolic blood pressure (M=123.75mmHg, % of change=1.12%) and diastolic blood pressure (M=74.38mmHg, % of change=5.79%) was increased on that of experimental group after 6 weeks experiment. But there was no significant difference between experimental group and control group. 2) Body weight was decreased on that of experimental group(M=56.54Kg, % of change=-1.60%) and that of control group(M=52.05, % of change=-0.99%) after 6 weeks. But there was no significant difference between experimental group and control group. 3) Body fat was decreased on that of experimental group(M=30.53%, % of change=-3.60%) and that of control group (M=28.75%, % of change=-3.52%) after 6 weeks. There was no significant difference between experimental group and control group. 4) Pulse rate was decreased on that of experimental group(M=69.19회/min, % of change -8.43%) and that of control group(M=76.0회/min, % change -0.07%) after 6weeks. There was significant difference(t=-2.621, P<0.05) between experimental group and control group. 5) Symptoms of stress response were decreased on that of experimental group(M=0.97) and that of control group(M=1.15) after 6 weeks. There was no significant difference between experimental group and control group. Therefore, adherence to aerobic exercise for 6 week seem to be affected mainly pulse rate of subjects. A futher study is necessary to determine the difference in the effect of variety exercise, programs, to study over 6 weeks, to produce professional educational program for exercise speciality nurses.

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A STUDY ON DEVELOPMENT AND PHYSICAL PROPERTIES OF STAINLESS STEEL ORTHODONTIC WIRES MADE IN KOREA (국산(國産)스테인레스강선계(鋼線系) 교정용선재(矯正用線材)의 개발(開發)과 물리적(物理的) 성질(性質)에 관(關)한 연구(硏究))

  • Sung, Jae-Hyun;Kwon, Oh-Won;Kyung, Hee-Moon;Lee, Kee-Dae
    • The korean journal of orthodontics
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    • v.19 no.2
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    • pp.7-24
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    • 1989
  • The physical properties of seven sizes of control groups and experimental group in stainless steel orthodontic wires were studied in tension, hardness, bending, torsion and observation of microstructure. The wires (0.40-0.90mm dia.) of round type were tested in the as-received condition. The wires of control groups were TRU-CHROME and REMANIUM, and experimental group was SK wire which was developed by ourselves and made in Korea. The results were as follows; 1. The chemical compositions of control groups and experimental group were austenite stainless steel wires of SOS 304. 2. Higher values of tensile and yield strength in tension were control group I, experimental group, control group II. Maximum tensile and yield strength of experimental group were $203.63{\pm}1.41kg/mm^2$ in 0.70mm diameter and $148.96{\pm}4.88kg/mm^2$ in 0.60mm diameter, and maximum elongation was $5.20{\pm}0.57%$ in 0.45mm diameter. 3. Hardness values of experimental group were similar to control groups. Maximum hardness values were $596.2{\pm}13.66Hv$ in 0.45mm diameter wire of control group I, $590.5{\pm}20.08Hv$ in 0.50mm diameter wire of control group II, and $563.6{\pm}5.35Hv$ in 0.70mm diameter wire of experimental group. 4. Torsion properties of experimental group were similar to control group I and more than control group II. Maximum torsion cycles were $31.8{\pm}2.48$ in 0.45mm diameter of control group I, $17.4{\pm}4.84$ in 0.60mm diameter of control group II, and $24.6{\pm}3.04$ in 0.45mm diameter of experimental group. 5. Maximum bending cycles of experimental group were smaller than control groups. Maximum bending cycles were $9.00{\pm}0.00$ in 0.50mm diameter wire of control group I, $10.0{\pm}0.82$ in 0.40mm diameter wire of control group II, and $8.0{\pm}1.26$ in 0.50mm diameter wire of experimental group. 6. Microstructures of experimental and control groups co-existed with martensited austenite structure and elongated austenite structure. 7. The direction of wire fracture was propagated parallel to torsion direction typically and there was no probability showing wire fracture at inclusions and surface scratches. 8. The type of wire fracture was brittle fracture at initiation site and ductile fracture at core.

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Effect of lumbar extensor strength according to lumbosacral angle change on chronic lumbar back pain patients (만성요통환자의 요천추 각도가 요부신전 근력에 미치는 영향)

  • Kim Kyoung-Tae;Park Rae-Joon
    • The Journal of Korean Physical Therapy
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    • v.16 no.1
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    • pp.14-31
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    • 2004
  • The Purpose of this study was to investigate the change of lumbar extensor strength according to lumbosacral angle on chronic lumbar back pain patients. For this investigation lumbar extensor strength was administered to 60 patients who were diagnosed chronic lumbar back pain The subjects was to investigate lumbosacral angle in standing position and it were calculated lumbar extensor strength by using Medex. The result of this study summarized are as follows ; 1. Total experimental group exhibited significantly higher difference than control group in lumbar extensor strength among all degree lumbosacral angle. 2. In the relationship between experimental group and control group in lumbar extensor strength among lumbosacral angle, all degree difference was revealed II, I, III order. 3. In the relationship between experimental group and control group in lumbar extensor strength among lumbosacral angle, I group difference was did not. 4. In the relationship between experimental group and control group in lumbar extensor strength among lumbosacral angle, all degree among II group was noted significantly difference except 24, 72 angle. 5. In the relationship between experimental group and control group in lumbar extensor strength among lumbosacral angle, control group was revealed higher muscle strength 48, 60, 72 angle, however no significantly difference was noted 0, 12, 24 angle. The study was objected difference of other group in both of experimental and control group. Because lumbar extensor weakness with bad position was gradually increased back pain, to Maintain normal lumbosacral angle befor exercising lumbar extensor strength was most important.

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An Experimental Study on the Effects of Structured Preoperative Teaching on Postoperative Recovery (계획된 수술전 교육이 수술후 회복에 미치는 영향에 관한 임상실험적 연구)

  • 김명숙
    • Journal of Korean Academy of Nursing
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    • v.14 no.2
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    • pp.38-46
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    • 1984
  • The purpose of this study was to test the effect of the structured preoperative teaching on post-operative recovery and to observe the effects of an structured preoperative teaching on the adult surgical patient's ventilatory function ability, the length of hospital stay, the number of analgesics within a 72 hour postoperative period, the length of early ambulation. The research question investigated in this study was: What would be the effects of a structured preoperative teaching upon the adult surgical patients postoperative recovery? This study was based on a sample of 40 patients who were scheduled for abdominal surgery. They were asssigned alternately to experimental and control group. Among 40 subjects, 20 were placed in the experimental group and 20 in the control group. Preoperative ventilation function testing of control and experimental subjects was done the evening before surgery and before the patient received the structured preoperative teaching. A structured preoperative teaching was given to the subjects in the exporimental group only by writer. Postoperative testing was done the 5th postoperative day. The data were collected over a period of two months, from Aug. 8 to Oct. 31, 1983. For the analysis of the data and test for the hypotheses, the t-test with mean difference was used. The results of this study regarding the four-hypotheses were as follows: 1. Experimental group which received structured preoperative eaching will have more increase to-cough and deep breathe as measured byhis forced vital capacity(FVC), forced expiratory volume 1 (FEV1), maximal voluntary volume 15 (MVV 15) than control group without structured preoperative teaching. The ventilation function ability was more increase in experimental group than in control group, the mean difference was statistically significant at 0.01 level. Hypotheses 1 was supported. 2. Experimental group with structured preoperative teaching will have more reduced the length of hospital stay than control group without structured preoperative teaching. The length of hospital stay of the experimental group and control group were 11.90 days and 16.05 days respectively. However, the difference was. not statistically significant at .05 level. Therefore the hypothese 2 was not supported. 3. Experimental group with structured preoperative teaching will have more reduce the number of analgesics within a 72 hour postoperative period than control group. The number of analgesics within a 72 hour' postoperative period of experimental group and control group were 1.65 times and 2.4 times. The difference was not statically significant at .05 level. Therefore, the hypotheses 3 was not supported. 4. Experimental group with structured preoperative. teaching will have more reduce the length of early ambulation than control group without structured preoperative teaching. The length of early ambulation of experimental group and control group were 2.2 days and 3.5 days respectively The difference was statistically signficant at 0.05 level. Thus the hypothess 4 was supported.

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The Wound Healing Effects of Opuntia Ficus-indica in Dogs (개에서 손바닥 선인장의 피부 결손창 치료 효과)

  • Lee Hyun sung;Cheong Jongtae;Park Hyun jung;Shin Tae-kyun;Kim Jae hoon;Lee Joo myoung
    • Journal of Veterinary Clinics
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    • v.22 no.1
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    • pp.43-49
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    • 2005
  • The aim of this study is to investigate the wound healing effects of the Opuntia ficus-indica. Four full-thickness skin wounds(2.5 cm × 2.5 cm) were made in different areas on the back in each of five dogs. Two wounds were used for wound size measurement and two for skin biopsy. The ten full-thickness wounds were treated with the extract of Opuntia ficus-indica, and the ten full-thickness wounds were treated with normal saline. The wound areas were measured every other day for three weeks after wounding. Statistical analysis was performed with the paired t-test. The wound healing rates were 32.9±4.0%, 28.2±7.1%, 42.2±4.1%, 55.0±4.3%, 76.6±2.8%, 86.8±2.3%, 94.0±1.l%, 97.3±0.8%, 99.3±0.3%, 99.8±0.2%, 100.0±0.0% in the experimental group, and 18.0± 8.2%, 13.S± 11.6%, 15.2±6.1 %, 36.9±8.8%, 62.4±4.1%, 80.0±2.3%, 86.0±1.4%, 94.0±0.9%, 96.9±0.8%, 97.8±0.3%, 99.7±0.1% in the control group on the 1/sup st/, 3/sup rd/, 5/sup th/, 7/sup th/, 9/sup th/, 11/sup th/, 13/sup th/, 15/sup th/, 17/sup th/, 19/sup th/, 21/sup st/ day. On the 17/sup th/ day, the wound closed above 99.9% in 1 dog of the experimental group. On the 19/sup th/ day, the wound closed above 99.9% in 3 dogs of the experimental group. On the 21/sup st/ day, the wound closed above 99.9% in 5 dogs of the experimental group, and 1 dog of the control group. The wound healing period was shortened by 2 to 4 days in the experimental group as compared with the control group. The tensile strength was 4,508±513 g/㎠ in the experimental group and 2,772±400 g/㎠ in the control group on the 21/sup st/ day after wounding. The tensile strength was significantly higher in the experimental group than in the control group(p< 0.05). Inflammation rapidly spread and disappeared in the experimental group but not in the control group. Fibroblast and vascularization were found on the 5/sup th/ day in both group and increased only in the experimental group on the 9/sup th/ day. The firs finding of epithelialization was on the 13/sup th/ day in the experimental group and the 21/sup st/ day in the control group. A significantly higher wound healing rate(p< 0.05), tensile strength(p< 0.05) and better histopathological findings were observed in the experimental group than in the control group throughout the experimental period. These results suggest that topical application of Opuntia ficus-indica extract can promote wound healing in dogs.

Effects of corrective exercises on selective functional movement assessment and health risk appraisal in middle-aged women

  • Kim, Jae Eun;Kim, Cheong;Kim, Sinseop
    • Physical Therapy Rehabilitation Science
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    • v.5 no.4
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    • pp.185-192
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    • 2016
  • Objective: The purpose of this study was to find the limited patterns of middle-aged women in selective functional movement evaluation and analyze the effects of pattern improvement exercises and general control groups on the Health Risk Appraisal (HRA). Design: Randomized controlled trial. Methods: The 31 subjects were physically healthy middle-aged women aged 40-59 living in Seoul, The subjects were randomly divided into an experimental group and a control group. Forty-three physically healthy women were originally recruited and randomly assigned to either the experimental group (n=22) or the control group (n=21). However, due to lack of participation, a total of seventeen subjects in the exercise group and fourteen subjects in the control group participated in the study. All subjects were tested using Selective Functional Movement Assessment (SFMA) and HRA for the baseline measurement and joined an exercise program of their group for one hour per session, twice a week for four weeks. The experimental group was provided with the corrective exercises and the control group was given the general fitness program. A follow-up test was conducted after eight weeks from the baseline measurement. Results: Both experimental and control group showed significant changes in SFMA and HRA scores (p<0.05). In the experimental group and control groups, the SFMA and HRA showed significant improvement from baseline to 4 weeks (p<0.05). Also, in the experimental group, the SFMA was significantly improved from baseline to 8 weeks (p<0.05). For the experimental group, there was a significant improvement in SFMA after 4 weeks compared to the control group (p<0.05). Conclusions: The corrective exercise in the experimental group had a positive effect on the SFMA score as well as the general squat exercise in the control group. The corrective exercise and general control group had the same positive effect on the HRA score.