• 운동영양학회지
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• 제23권1호
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• pp.7-12
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• 2019

[Purpose] The purpose of the study was to determine the combined effects of resveratrol supplementation with high-flow LSS on mitochondrial biogenesis in human vascular endothelial cells. [Methods] Cultured human umbilical vein endothelial cells were treated with 20 μM of RSV. For the shear experiments, cells grown to a >90% confluence were exposed to physiological levels of LSS (5 to 20 dyne/cm2) for 12 to 36 hours using a cone and plate shear apparatus. Gene expressions were analyzed by western blotting. [Results] Depletion of mitochondrial integrity was directly associated with increase in endothelial activation/dysfunction. The expressions of mitochondrial biogenesis regulator genes, such as SIRT1, PGC-1α, and TFAM, and the mitochondrial contents were significantly increased after treatment with both resveratrol and high-flow LSS for 12 hours. However, supplementation of resveratrol to high-flow LSS for a prolonged duration had no synergistic effect on the levels of mitochondrial biogenesis regulator gene expressions and mitochondrial content compared to the LSS treatment alone. [Conclusion] The present study demonstrated that the supplementation of resveratrol to high-flow LSS has no synergistic effects on enhancing mitochondrial integrity in human vascular endothelial cells.

• Structural Engineering and Mechanics
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• 제20권5호
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• pp.495-504
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• 2005

This article explores a constitutive equation that is able to correlate stress, strain and strain rate. In order to show the advantages of the constitutive equation here proposed and how its material parameters are obtained, data extracted from the literature, for materials as different as polymers and metallic alloys, are used. Finite element simulation of the impact behaviour of a beam is presented to highlight the care one needs to exercise when using the more traditional Cowper-Symonds equation. The present constitutive equation has shown to be accurate for a wide range of strains, stresses and strain rates.

• 문화기술의 융합
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• 제6권2호
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• pp.341-348
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• 2020

본 연구의 목적은 4주간 20대 성인에게 앉은자세와 누운자세에 따른 복식호흡운동을 적용하였을 때 호흡기능과 배근육의 근활성도를 비교하여 어떤 자세에서의 운동이 효과적인지 알아보고자 하였다. 기립자세에서는 호흡운동 후 일초량이 가장 큰 수치를 보였고 누운자세에서는 호흡운동 전 일초량과 1초간노력성날숨량이 가장 크게 나타났다. 두자세의 복식호흡운동 전후 일초량과 날숨량 분산분석결과 운동전일초량, 운동후일초량, 운동전1초간날숨량, 운동후1초간날숨량 모두 유의한 차이를 보이며, 두 자세에서 복식호흡 전후 차이를 알 수 있었다. 기립자세, 누운자세에서 운동전에는 왼쪽 복직근, 운동후에는 오른쪽 복직근이 가장 높은 근활성도를 보였다. 두 자세 운동의 반복측정한 분산분석 결과 운동 전과 후의 양쪽 복직근과 외복사근은 근활성도 모두 차이를 보이지 않았다(p>.05). 기립자세에서 운동 전과 후에 왼쪽 외복사근이 유의한 차이를 보였고(p<0.05), 운동전과 후 FEV1/FVC와 노력성 호기량이 유의한 차이를 보였다(p<0.05). 운동 전과 후 왼쪽 외복사근이 누운자세에서 가장 높은 근활성도를 보였고 노력성 호기량은 가장 낮은 근활성도를 보였다. 운동 전과 후 호흡량 및 근활성도의 반복측정된 분산분석 결과에서 오른쪽 복직근에서 유의한 차이를 보였다(p<.05). 이를 통해 앉은 자세와 비스듬히 누운자세 두가지 자세에서 복식호흡 운동을 적용 하였을 때 호흡기능과 배근육의 근활성도 전,후를 비교하기 위해서는 두가지 자세에서의 운동 전,후 호흡과 근활성도 평가가 필요하고 평가에 따라서 어떤 자세에서의 운동이 더 효과적인지 알 수 있었다. 추후 연구에서는 좀 더 세분화되고 정확한 호흡기능과 근활성도를 알아보는 다양한 연령대의 사람들에게 장기간의 중재를 통해 파악하는 연구가 필요할 것으로 사료된다.

• 대한물리치료과학회지
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• 제18권3호
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• pp.9-16
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• 2011

Background : Smoking reduces the ability of the lungs to function. In particular, smoking reduces the vital capacity of the lungs, which is the amount of air the lungs can take in. This reduction in vital capacity has several important health effects. Purpose : The purpose of this study, therefore was to examine the effects of the respiratory muscle exercise on peak expiratory flow and respiratory muscle strength. Methods : For an experimental research design, it was employed 20 young healthy subjects and these subjects were assigned into two groups; a smoking group(n=10) and an non-smoking group(n=10). All groups were participated in respiratory muscle exercises twice a week for 5 weeks in same condition. For comparison between before and after for post treatment, it was analysed as paired t-test and ANCOVA. Results : The result of this study were as follows; In the case of smoking group, there were significant differences, from $427.77{\pm}76.61$ l/min to $526.66{\pm}58.52$ l/min of peak respiratory flow, from $94.33{\pm}22.07$ kg to $102.16{\pm}21.60$ kg of abdominal muscle strength between the before and the after of respiratory muscle strength exercises. In the case of nonsmoking group, there were significant differences, from $449.54{\pm}77.47$ l/min to $553.18{\pm}61.32$ l/min of peak respiratory flow, from $93.41{\pm}19.21$ kg to $101.58{\pm}18.92$ kg of abdominal muscle strength between the before and the after of respiratory muscle strength exercises. Conclusion : These results were suggested that the peak respiratory flow and muscle strength were improved after respiratory muscle strength exercises.

• 한국체육학회지인문사회과학편
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• 제54권1호
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• pp.535-544
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• 2015

이 연구는 노인 여성에 대한 저항성 훈련 시 혈류제한(blood flow restriction)을 적용할 경우 저강도 운동을 통해서도 하지의 근력과 근육량을 효과적으로 향상시킬 수 있는지를 검증하기 위해 수행되었다. 총 16명의 노인 여성(연령 70.9±4.6)을 저강도 운동 집단(30% 1 RM, n=8)과 고강도 운동 집단(75% 1 RM, n=8)으로 구분하였다. 두 그룹 모두 우측 하지는 대퇴 근위부에 혈류제한용 커프(cuff)를 착용한 상태에서, 좌측 하지는 혈류제한 장치 없이 동일한 운동을 수행한 후 트레이닝 전·후의 근육량과 근력 변화를 분석하였다. 저항성 운동 프로그램은 leg press, leg extension, leg curl을 12회 반복으로 3세트씩 총 10주간 주 2회 실시하였다. 자기공명영상분석기(MRI)로 근 횡단면적(CSA)과 근육량을 산출하였으며, 체성분 변화는 이중에너지 방사흡수 계측기(DEXA), 근력 평가는 등속성 운동 장비(HUMAC Norm)를 이용하였다. 연구를 통해 10주간의 저항성 훈련 후 혈류제한을 적용한 상태에서 고강도 운동을 수행한 집단의 대퇴사두근 근횡단면적(15.2%, p<.001)과 근육량(13.8%, p<.001)이 증가하였으며 이러한 긍정적 변화는 혈류제한 상태에서 저강도로 운동한 집단의 횡단면적(9.8%, p<.001)과 근육량(6.9%, p<.001) 변화에서도 확인할 수 있었다. 한편, 근력은 운동 수행만으로도 향상되었으나 혈류를 제한할 경우 향상도가 더 높은 경향을 보였다. 따라서 이 연구는 혈류제한을 적용할 경우 저항성 운동을 저강도로 수행하더라도 노인 여성의 근 비대와 근력 증가에 효과적으로 작용할 가능성을 시사한다.

• 재활치료과학
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• 제11권3호
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• pp.7-22
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• 2022

목적 : 본 연구는 연하장애를 가진 뇌졸중 환자에게 적용된 혀 운동을 체계적으로 분석한 논문이다. 혀 운동에 대한 전반적인 효과를 검증하고, 현재 이루어지고 있는 혀 운동에 대한 경향을 파악하는데 그 목적을 가지고 근거를 제공하고자 한다. 연구방법 : PRISMA(Preferred Reporting Items for Systematic Reviews and Meta-Analysis) 체크리스트 및 흐름도를 이용하여 체계적 고찰을 시행하였다. 데이터베이스는 PubMed, MEDLINE, CINAHL, RISS, e-article 을 통해 문헌 검색을 진행하였다. 본 연구에 사용된 문헌의 수는 총 6편이었고, 문헌의 질을 평가하기 위하여 PEDro scale(Physiotherapy Evidence Database scale)을 사용하였다. 결과 : 분석된 논문 6편에서 3가지의 중재 방법이 포함되었다. 혀 운동의 종류로는 혀 근력훈련 3편, 혀 근력 및 정확도 훈련 2편으로 모두 아이오와 구강 수행 도구를 통한 중재를 시행하였고, 혀 신장훈련을 적용한 논문이 1편이었다. 조사된 문헌에서 시행한 중재 별 치료 효과는 모두 효과가 있는 것으로 확인되었다. 하지만 대부분 표본수가 적어 일반화 시키기는 어려울 것으로 생각되며, 실험군과 대조군 비교 시 몇몇 그룹 간에 유의한 차이가 발견되지 않은 결과들이 있는 만큼 전통적 연하재활치료도 구강기 연하장애를 가지고 있는 환자들에게 적절한 치료 방법으로 판단된다. 결론 : 본 연구는 작업치료사들이 연하장애를 가진 뇌졸중 환자들에게 혀 운동을 적용함에 있어 효율적인 연하재활치료를 제공하는데 도움을 줄 수 있을 것이며, 혀 운동의 효과를 알아보기 위해 더 많은 연구축적이 이루어져야 할 것으로 생각된다.

• 순환기질환의공학회:학술대회논문집
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• 순환기질환의공학회 2002년도 제2회 학술대회 초록집
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• pp.3-18
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• 2002

Hemorheology plays an important role in atherosclerosis. Hemorheologic properties of blood include whole blood viscosity, plasma viscosity, hemaocrit, RBC deformability and aggregation, and fibrinogen concentration in plasma. Blood flow is determine by three parameters (pressure, lumen diameter, and whole blood viscosity), whole blood viscosity is one of the key physiological variables. However, the significance of whole blood viscosity has not yet not been fully appreciated. Whole blood viscosity has a unique property, non-Newtonian shear-thinning characteristics, which is primarily due to the presence of RBCs. Hence, RBC deformability and aggregation directly affect the magnitude of blood viscosity, and any factors or diseases affecting RBC characteristics influence blood viscosity. Therefore, on can see that whole blood viscosity is the causal mechanism by which traditional risk factors such as hypertension, hyperlipidemia, smoking, exercise, obesity, age, and gender are related to atherogenesis. In this regard, we included whole blood viscosity in the three key determinants of injurious pulsatile flow that results in mechanical injury and protective adaptation in the arterial system. Because whole blood viscosity is a potential predictor of cardiovascular diseases, it should be measured in routine cardiovascular profiles. Incorporating whole blood viscosity measurements into a standard clinical protocol could improve our ability to identify patients at risk for cardiovascular disease and its complications.

• 대한수의학회지
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• 제50권1호
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• pp.49-53
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• 2010

A 5-year-old female Cocker spaniel dog (body weight 7.0 kg) was presented with primary complaints of exercise intolerance and loud precordial thrill which was noticed since she was a puppy. Physical examination revealed a grade V/VI continuous murmur over the maximal point of the left basal area, bounding femoral pulse, but no differential cyanosis. Tall R waves were detected in electrocardiogram, suggesting left ventricular enlargement. Diagnostic imaging studies showed enlarged left ventricle, bulged descending aorta (dAo), markedly dilated right pulmonary artery, and continuous shunt flow between the dAo and main pulmonary artery. Based on these findings, the dog was diagnosed as left to right shunted patent ductus arteriosus (PDA). The patent ductus arteriosus was treated by lodging a PDA duct occluder via the transvenous approach. Clinical signs were markedly improved after the ductal occlusion, the shunt flow was mildly persistent. The case presented is the first case of PDA occluded by the PDA duct occluder via the transvenous approach in a small breed of dog. Although the residual shunt flow was mildly persisted, the dog was clinically normal without detectable murmurs.

• 기본간호학회지
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• 제16권2호
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• pp.214-222
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• 2009

Purpose: The purpose of this study was to evaluate the effects of a walking-support program on the pulmonary ventilatory functions of elderly people who had undergone upper-abdominal surgery. Method: The study was a quasi-experimental research design. There were 26 partcipants who were admitted for upper-abdominal surgery to P University Hospital in B city. Walking exercise education was provided individually to the experimental group the day before their operation and 20 minutes a day for five days after the surgery using the 'Walking Exercise Guide Document'. Pulmonary ventilatory function was with FVC (Forced Vital Capacity), PEF (Peak Expiratory Flow), FEVI (Forced Expiratory Volume in 1 Second), FER (Forced Expiratory Ratio), Oxygen Saturation, and VAS (Visual Analog Scale). Results: The objective indexes of pulmonary ventilatory function were not significantly different between the two groups, but the subjective index was significantly different. Conclusion: With the above results, the walking support program could be an effective nursing intervention for improving pulmonary ventilatory function of surgical patients.

• 대한물리치료과학회지
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• 제11권2호
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• pp.46-56
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• 2004

The purpose of this study was to investigate the effect of watsu therapy on muscle tone in adult hemiparesis patient after stroke. The subject was a 66 year old patient with left hemiparesis whose self gait was independent with minimal assist. The subject was ambulatory with some degree of limitation and demonstrated a little tremor and asymmetry in the body. A multiple treatment design(A-B-C-B) for a single-subject research was used for this study. The watsu therapy consisted of basic moves, head cradle, underfar leg, near leg cradle in watsu I (transition flow), for 25 minutes, which lasted 12 sessions for a total 21 sessions. A baseline was conducted for a first time and a general ROM exercise was conducted after the first watsu therapy. Tone assessment scale was tested : 1. posturing at rest 2. response to passive movement 3. associated reaction Comparing to the baseline and general ROM exercise, The results showed that the watsu therapy had some positive effects on improvement of three tests and there was a more positive effects of both response to passive movement and associated reaction.