• Title/Summary/Keyword: exercise flow

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Effects of resveratrol on laminar shear stress-induced mitochondrial biogenesis in human vascular endothelial cells

  • Kim, Ji-Seok;Park, Joon-Young
    • Korean Journal of Exercise Nutrition
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    • v.23 no.1
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    • pp.7-12
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    • 2019
  • [Purpose] The purpose of the study was to determine the combined effects of resveratrol supplementation with high-flow LSS on mitochondrial biogenesis in human vascular endothelial cells. [Methods] Cultured human umbilical vein endothelial cells were treated with 20 μM of RSV. For the shear experiments, cells grown to a >90% confluence were exposed to physiological levels of LSS (5 to 20 dyne/cm2) for 12 to 36 hours using a cone and plate shear apparatus. Gene expressions were analyzed by western blotting. [Results] Depletion of mitochondrial integrity was directly associated with increase in endothelial activation/dysfunction. The expressions of mitochondrial biogenesis regulator genes, such as SIRT1, PGC-1α, and TFAM, and the mitochondrial contents were significantly increased after treatment with both resveratrol and high-flow LSS for 12 hours. However, supplementation of resveratrol to high-flow LSS for a prolonged duration had no synergistic effect on the levels of mitochondrial biogenesis regulator gene expressions and mitochondrial content compared to the LSS treatment alone. [Conclusion] The present study demonstrated that the supplementation of resveratrol to high-flow LSS has no synergistic effects on enhancing mitochondrial integrity in human vascular endothelial cells.

Prediction of the dynamic flow stress

  • Alves, Marcilio
    • Structural Engineering and Mechanics
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    • v.20 no.5
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    • pp.495-504
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    • 2005
  • This article explores a constitutive equation that is able to correlate stress, strain and strain rate. In order to show the advantages of the constitutive equation here proposed and how its material parameters are obtained, data extracted from the literature, for materials as different as polymers and metallic alloys, are used. Finite element simulation of the impact behaviour of a beam is presented to highlight the care one needs to exercise when using the more traditional Cowper-Symonds equation. The present constitutive equation has shown to be accurate for a wide range of strains, stresses and strain rates.

The effect of postural abdominal breathing exercise on posture muscle activity and respiratory function in adults in their 20s (자세에 따른 복식호흡 운동이 20대 성인의 자세근육 활성도 및 호흡 기능에 미치는 영향)

  • Lee, Jun-cheol
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.2
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    • pp.341-348
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    • 2020
  • This research is to find out which position is more effective on exercise. This study compared paricipants in their twenties on sitting position & standing position doing abdominal breathing of their respiration & abdominal muscle activation for 4 weeks. In sitting position, FEV1 was the biggest after breathing exercise. In standing position, the gap was biggest between the FEV1 & forced expiratory flow before and after the exercise. In standing and supine position, Lt. rectus abdominis before exercise and Rt. rectus abdominis after exercise muscle activities were the biggiest. Both posture exercise of repeated measure of analysis result, before and after the exercise of the rectus abdomonis muscle and external oblique muscle were not difference in both muscle activity(p>.05). Left Musculus obliquus externus abdominis before and after physical exercise, it's showed a meaningful difference(p<0.05). Before and after exercise, saw a meaningful difference the efforts of FEV1/FVC(p<0.05). The left external oblique abdominis muscle showed the most muscle activity in the supine position before/after exercising, the efforts expiratory showed the lowest muscle activity.The results from the repeated measures ANOVA regarding to before/after the volume and muscle activity, it showed significant difference between at the right rectus abdominis muscle(p<.05). This study finally gathered data about the muscle activity according to the position. This could be used to find in what position the abdominal breath exercise is the post effective & a new treatment for the patients who has worsened respiration function.

Changes of Respiratory Ability According to Respiratory Muscle Exercises for Smokers and Non-smokers in Their Twenties (20대 흡연자와 비흡연자의 호흡근 강화 운동에 따른 호흡능력의 변화)

  • Lee, Sam-Cheol;Jung, Chul-Hyun;Lee, Eun-Suk;Lee, Hae-Ho;Joung, Young-Hwan;Chae, Hye-Jin;Choi, Jung-A;Lee, Hyun-Chul;Oh, Sang-Boo;Son, Kyung-Hyun
    • Journal of Korean Physical Therapy Science
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    • v.18 no.3
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    • pp.9-16
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    • 2011
  • Background : Smoking reduces the ability of the lungs to function. In particular, smoking reduces the vital capacity of the lungs, which is the amount of air the lungs can take in. This reduction in vital capacity has several important health effects. Purpose : The purpose of this study, therefore was to examine the effects of the respiratory muscle exercise on peak expiratory flow and respiratory muscle strength. Methods : For an experimental research design, it was employed 20 young healthy subjects and these subjects were assigned into two groups; a smoking group(n=10) and an non-smoking group(n=10). All groups were participated in respiratory muscle exercises twice a week for 5 weeks in same condition. For comparison between before and after for post treatment, it was analysed as paired t-test and ANCOVA. Results : The result of this study were as follows; In the case of smoking group, there were significant differences, from $427.77{\pm}76.61$ l/min to $526.66{\pm}58.52$ l/min of peak respiratory flow, from $94.33{\pm}22.07$ kg to $102.16{\pm}21.60$ kg of abdominal muscle strength between the before and the after of respiratory muscle strength exercises. In the case of nonsmoking group, there were significant differences, from $449.54{\pm}77.47$ l/min to $553.18{\pm}61.32$ l/min of peak respiratory flow, from $93.41{\pm}19.21$ kg to $101.58{\pm}18.92$ kg of abdominal muscle strength between the before and the after of respiratory muscle strength exercises. Conclusion : These results were suggested that the peak respiratory flow and muscle strength were improved after respiratory muscle strength exercises.

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Effect of Low-intensity Resistance Training with Blood Flow Restriction on Muscle Volume and Strength in Elderly Women (저강도의 저항성 운동 시 혈류제한 적용이 노인여성의 근 비대와 근력 향상에 미치는 영향)

  • Yeo, Hyo-Seong;Kim, Hyo-Jeong
    • 한국체육학회지인문사회과학편
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    • v.54 no.1
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    • pp.535-544
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    • 2015
  • This study was performed to determine the effect of low-intensity resistance training with blood flow restriction (BFR) on muscle volume and strength in elderly women. Sixteen elderly women (70.9±4.6 years) were divided into low (30% 1RM) and high (75% 1RM) intense resistance training groups. Tourniquet cuff (Zimmer, Germany) for BFR was applied only to the right leg during the training period. All subjects performed unilateral leg press, leg extension and leg curl (3 sets×12 repetitions) for 10 weeks (2d/wk). Blood pressure was increased from 110 to 240 mmHg during the training period at the most proximal region of exercised leg. Muscle volume and cross-sectional area (CSA) were measured by MRI and body composition was monitored by dual-energy X-ray absorptiometry (DEXA) and isokinetic muscular strength were analyzed in both legs. The quadriceps CSA (15.2%, p<.001) and muscle volume (13.8%, p<.001) were increased in high-intense trained leg with BFR and the increased rate was highest among groups. The quadriceps CSA (9.8%, p<.001) and muscle volume (6.9%, p<.001) were increased in low-intensity training group with BFR and their increased rates were higher than control groups. The strength by exercise training was significantly improved in all groups and tended to be higher in BFR groups. These results demonstrate low-intensity resistance training with blood flow restriction could be an effective way to improve muscle volume and strength in elderly women.

Effect of Tongue Exercise on Stroke Patients With Dysphagia : A Systematic Review (혀 운동(tongue exercise)이 연하장애를 가진 뇌졸중 환자에게 미치는 효과 : 체계적 고찰)

  • Son, Yeong Soo;Choi, Yoo Im
    • Therapeutic Science for Rehabilitation
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    • v.11 no.3
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    • pp.7-22
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    • 2022
  • Objectives : This study was a systematic review of tongue movements in stroke patients with dysphagia. This study aimed to provide a basis for verifying the effects of tongue movement and identifying the tendency of tongue movement. Methods : A systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist and flow chart. PubMed, MEDLINE, CINAHL, RISS, and e-articles databases were searched. A total of six documents were investigated, and the PEDro scale was used to evaluate the quality of the papers. Results : Three intervention methods were included in the six papers analyzed. Regarding the type of tongue exercise, three TPRT (Tongue to Palate Resistance Trainings) and two TSAT (Tongue Strength and Accuracy Training) were mediated through the IOPI (Iowa Oral Performance Instrument), and only one study applied TSE (Tongue Stretching Exercise). The treatment effects for each intervention implemented in the literature were confirmed to be effective. However, generalizability of findings is difficult because of the small sample size. Further, no significant difference was found between the experimental and control groups. Conclusions : This study can help occupational therapists provide efficient swallowing rehabilitation treatment by applying tongue exercises to stroke patients with dysphagia. More research should be conducted to determine the effects of tongue exercise.

Hemorheology and Cardiovascular Disease

  • Cho, Young-I.;Kensey, Kenneth R.
    • 순환기질환의공학회:학술대회논문집
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    • 2002.11a
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    • pp.3-18
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    • 2002
  • Hemorheology plays an important role in atherosclerosis. Hemorheologic properties of blood include whole blood viscosity, plasma viscosity, hemaocrit, RBC deformability and aggregation, and fibrinogen concentration in plasma. Blood flow is determine by three parameters (pressure, lumen diameter, and whole blood viscosity), whole blood viscosity is one of the key physiological variables. However, the significance of whole blood viscosity has not yet not been fully appreciated. Whole blood viscosity has a unique property, non-Newtonian shear-thinning characteristics, which is primarily due to the presence of RBCs. Hence, RBC deformability and aggregation directly affect the magnitude of blood viscosity, and any factors or diseases affecting RBC characteristics influence blood viscosity. Therefore, on can see that whole blood viscosity is the causal mechanism by which traditional risk factors such as hypertension, hyperlipidemia, smoking, exercise, obesity, age, and gender are related to atherogenesis. In this regard, we included whole blood viscosity in the three key determinants of injurious pulsatile flow that results in mechanical injury and protective adaptation in the arterial system. Because whole blood viscosity is a potential predictor of cardiovascular diseases, it should be measured in routine cardiovascular profiles. Incorporating whole blood viscosity measurements into a standard clinical protocol could improve our ability to identify patients at risk for cardiovascular disease and its complications.

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Transjugular occlusion of patent ductus arteriosus using an Amplatz canine ductal occluder in a Cocker spaniel dog

  • Choi, Ran;Hyun, Changbaig
    • Korean Journal of Veterinary Research
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    • v.50 no.1
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    • pp.49-53
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    • 2010
  • A 5-year-old female Cocker spaniel dog (body weight 7.0 kg) was presented with primary complaints of exercise intolerance and loud precordial thrill which was noticed since she was a puppy. Physical examination revealed a grade V/VI continuous murmur over the maximal point of the left basal area, bounding femoral pulse, but no differential cyanosis. Tall R waves were detected in electrocardiogram, suggesting left ventricular enlargement. Diagnostic imaging studies showed enlarged left ventricle, bulged descending aorta (dAo), markedly dilated right pulmonary artery, and continuous shunt flow between the dAo and main pulmonary artery. Based on these findings, the dog was diagnosed as left to right shunted patent ductus arteriosus (PDA). The patent ductus arteriosus was treated by lodging a PDA duct occluder via the transvenous approach. Clinical signs were markedly improved after the ductal occlusion, the shunt flow was mildly persistent. The case presented is the first case of PDA occluded by the PDA duct occluder via the transvenous approach in a small breed of dog. Although the residual shunt flow was mildly persisted, the dog was clinically normal without detectable murmurs.

The Effects of Walking-Support Program on the Pulmonary Ventilatory Functions of Elders Following Upper-abdominal Surgery (수술 후 보행지지 프로그램이 노인 상복부 수술환자의 폐 환기능 회복에 미치는 효과)

  • Park, Hyoung-Sook;Kim, Nam-Hee;Kim, Eun-Sim
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.16 no.2
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    • pp.214-222
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    • 2009
  • Purpose: The purpose of this study was to evaluate the effects of a walking-support program on the pulmonary ventilatory functions of elderly people who had undergone upper-abdominal surgery. Method: The study was a quasi-experimental research design. There were 26 partcipants who were admitted for upper-abdominal surgery to P University Hospital in B city. Walking exercise education was provided individually to the experimental group the day before their operation and 20 minutes a day for five days after the surgery using the 'Walking Exercise Guide Document'. Pulmonary ventilatory function was with FVC (Forced Vital Capacity), PEF (Peak Expiratory Flow), FEVI (Forced Expiratory Volume in 1 Second), FER (Forced Expiratory Ratio), Oxygen Saturation, and VAS (Visual Analog Scale). Results: The objective indexes of pulmonary ventilatory function were not significantly different between the two groups, but the subjective index was significantly different. Conclusion: With the above results, the walking support program could be an effective nursing intervention for improving pulmonary ventilatory function of surgical patients.

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The Effect of Watsu Therapy on Muscle Tone in Adult Hemiparesis Patient After Stroke (Watsu 치료가 뇌졸중 이후 성인 편부전마비환자의 근긴장도에 미치는 영향)

  • Chon, Seung-Chul
    • Journal of Korean Physical Therapy Science
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    • v.11 no.2
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    • pp.46-56
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    • 2004
  • The purpose of this study was to investigate the effect of watsu therapy on muscle tone in adult hemiparesis patient after stroke. The subject was a 66 year old patient with left hemiparesis whose self gait was independent with minimal assist. The subject was ambulatory with some degree of limitation and demonstrated a little tremor and asymmetry in the body. A multiple treatment design(A-B-C-B) for a single-subject research was used for this study. The watsu therapy consisted of basic moves, head cradle, underfar leg, near leg cradle in watsu I (transition flow), for 25 minutes, which lasted 12 sessions for a total 21 sessions. A baseline was conducted for a first time and a general ROM exercise was conducted after the first watsu therapy. Tone assessment scale was tested : 1. posturing at rest 2. response to passive movement 3. associated reaction Comparing to the baseline and general ROM exercise, The results showed that the watsu therapy had some positive effects on improvement of three tests and there was a more positive effects of both response to passive movement and associated reaction.

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