• 제목/요약/키워드: evaluated

검색결과 61,398건 처리시간 0.065초

미세먼지 PM10으로 손상을 유도한 각질형성세포에서 청각 (Codium fragile) 추출물의 항노화 효과 (Anti-aging effect of Codium fragile extract on keratinocytes damaged by fine dust PM10)

  • 김보애
    • 대한본초학회지
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    • 제38권4호
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    • pp.45-52
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    • 2023
  • Objectives : Fine dust caused by environmental pollution cause oxidative damage and skin aging. In this study, The possibility of using the Codium fragile extract (CFE) as an anti-aging product for skin improvement was evaluated by confirming the protective effect of skin cells from PM10 (particulate matter 10) through inhibition of ROS and MMPs. Methods : In this study, elastase and collagenase inhibitory activities were evaluated. Cell viability was evaluated by treating keratinocytes (HaCaT cell line) with CFE at various concentrations. The cytoprotective effect from PM10 in keratinocyteswas evaluated using the 3-[4,5-dimethylthiazol]-2-yl]-2,5-diphenyl-tetrazoliumbromide (MTT) assay. ROS (reactive oxygen species) was measured in keratinocytes damaged by PM10 using DCF-DA (2′,7′-dichlorofluorescin diacetate) fluorescence staining. As an anti-aging effect of CFE, MMP-1 (matrix metalloproteinase-1) and MMP-1 (matrix metalloproteinase-9) inhibitory activities were evaluated. Results : As a result, CFE decreased the activity of elastase and collagenase. As a result of evaluating the toxicity of CFE, it is non-toxic at a concentration of 10 to 80 ㎍/㎖. Although cell viability of HaCaT cells treated with PM10 decreased, cell viability increased by 38% when treated with CFE 80 ㎍/㎖. Also, ROS decreased by 8.4%, and MMP-1 and MMP-9 decreased at CFE 80 ㎍/㎖. Conclusions : CFE showed excellent cell protection effect, and it is considered that it can be used in anti-aging products for skin improvement by effectively inhibiting ROS and MMPs from keratinocyte damage caused by fine dust.

무인항공기 임무장비용 압전 마운트 시스템의 진동 제어 성능 평가 (Evaluation of Vibration Control Performance of Camera Mount System for UAV)

  • 오종석;손정우;최승복
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2009년도 추계학술대회 논문집
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    • pp.407-412
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    • 2009
  • In the present work, vibration control performance of active camera mount system for unmanned aero vehicle (UAV) is evaluated. An active mount featuring inertia type of piezostack actuator is designed and manufactured. Then, vibration control performances are experimentally evaluated. A camera mount system with four active mounts is constructed and mechanical model is established. The governing equation for the camera mount system is obtained and control model is constructed in state space model. Sliding mode controller which has inherent robustness to external disturbance is designed and implemented to the system. Vibration control performances are evaluated at each mount and center of gravity point. Effective vibration performances are obtained and presented in time and frequency domains.

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Resonance Integral of Neptunium(237Np) from Energy Dependent Differential Neutron Capture Cross-Section by Using the Linac TOF Method and C6D6 Scintillation Spectrometer

  • Lee, Sam-Yol
    • 한국방사선학회논문지
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    • 제5권4호
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    • pp.217-221
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    • 2011
  • $^{237}Np$ is very important material in the fission products of nuclear reactors. Resonance integral(RI) tests of this material is necessary to check between the experiments and the evaluated data. Such feedback to the evaluated data is very important to correct data and improve of codes. The RI for the $^{237}Np(n,{\gamma})^{238}Np$ reaction were measured by using the 46-MeV electron linear accelerator (linac) at the Research Reactor Institute, Kyoto University (KURRI). The measurement was performed in the energy region from 0.005 eV and 10 keV. RI obtained as 804.7 barns, compared with those of the evaluated data in JENDL-4.0 and Mughabghab.

상어 표피 모사 리블렛 구조의 젖음성 평가 (Wettability of Biomimetic Riblet Surface like Sharkskin)

  • 공유식;김태완
    • Tribology and Lubricants
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    • 제29권5호
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    • pp.304-309
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    • 2013
  • Shark skin has functionalities such as self-cleaning and antifouling; it also exhibits excellent drag reduction owing to a hierarchical structure of microgrooves and nanometer-long chain mucus drag reduction interfaces around the shark body. In this study, the wettability of a shark skin surface and its replicas are evaluated. First, a shark skin template is taken from a real shark. Then, shark skin replicas are produced directly from a shark skin template, using a micromolding technique. The quantitative replication precision of the shark skin replicas is evaluated by comparing the geometry of the shark skin template to the replica using 2D surface profiles. Contact angles at the solid-air-water interfaces are evaluated for the shark skin template and its replicas under two conditions: with and without hydrophobic coating. The results show that the microriblets on shark skin improve the hydrophobic feature and play a critical role in self-cleaning.

Carsington 댐의 사면안정 해석 (Slops Stability Analysis of Carsington Dam)

  • 손준익;안상로
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 1991년도 추계학술발표회 논문집 지반공학에서의 컴퓨터 활용 COMPUTER UTILIZATION IN GEOTECHNICAL ENGINEERING
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    • pp.75-86
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    • 1991
  • 본 논문에서는 지반공학 소식 창간호에 게제된 Carsington 댐의 파괴에 관하여 고찰하였으며, 해석 결과에 근거하여 댐 파괴요인과 그 영향에 관하여 논술하였다. 본 해석에서는 파괴후의 현장조사에서 나타난 황색점토층 내에 이미 존재하던 전단변위에 대한 영향과 이 연약점토층을 통과하는 파괴면의 진행성 파괴상황을 중점적으로 분석하였다. 가능한 현장조건을 대표하는 수치로 변화시켜 각 조건별 안전도 계산치를 비교하고, 댐 파괴시의 평균강도를 가장 잘 대표하는 현장 지반조건을 평가하였다.

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Significant Parameters for Assessing Soil Contaminant-Leaching to Groundwater and Determining Soil Sample Size in Field Survey

  • Jeong, Seung-Woo;An, Youn-Joo
    • Environmental Engineering Research
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    • 제13권2호
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    • pp.73-78
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    • 2008
  • For a given soil-contaminated site, a level of soil contamination is characterized and decisions on risk may be made from the risk assessment. The study evaluated critical design factors for the determination of sample size in the sampling design plan and the assessment of soil contaminant- leaching to groundwater. Two variables, the minimum relative detectable difference (T) and coefficient of variation (CV) were evaluated for the sample size determination. The minimum number of samples can be appropriately determined by CV under a T value greater than or equal to 0.2. Soil-contaminant leaching to groundwater was evaluated by using the Soil Screening Level equation of U.S. Environmental Protection Agency and the Risk Based Screening Level equation of American Society for Testing and Materials, with the same input parameters. The groundwater concentrations estimated from soil contaminant concentrations were significantly affected by the Darcy velocity of groundwater and the organic content of soil.

작업자세와 Push-Pull 작업에 따른 작업부하 측정에 관한 연구 (The Study of Work Load by the Working Posture and the Push-Pull Work)

  • 심정훈;이상도
    • 한국산업경영시스템학회:학술대회논문집
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    • 한국산업경영시스템학회 2002년도 춘계학술대회
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    • pp.63-68
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    • 2002
  • This study performed to evaluated musculoskeletal disorders(MSDs) during sitting work. The musculskeletal system is affected by various work factors such as strength, weight, posture, repetition, duration and exertion. Ergonomic study on sitting work is necessary to evaluate these factors affecting human body. But the strength and work load data by the work factors are insufficient in Korea. Therefore, this study evaluated the work load using the elcctromyogram(EMG) and measured the arm strength by arm posture and push pull work during sitting work. to evaluated muscle load, the vertical height and horizontal angle of arm were adjusted around acromion. And EMG data were recorded on pc during the test.

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Study of Non-uniform Plasma Layer Variation with Optically-Controlled Microwave Pulses

  • Wang, Xue;Yun, Ji-Hun;Kim, Yong-K.
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 하계학술대회 논문집
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    • pp.90-91
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    • 2009
  • We study of the variation on non-uniform plasma in different layer of the semiconductor. The transient response in different plasma layer has been evaluated theoretically. The reflection function of dielectric microstrip lines resulting from the presence of plasma are evaluated by the transmission line model. The diffusion length is small compared to the absorption depth. The variation of characteristic response in plasma layer with microwave pulses which has in localized has been evaluated.

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탐색적 방법에 의한 건축공간 배치계획 최적화에 대한 고찰 (A Study on the Optimized Architectural Space Planning by Searching Algorithm Method)

  • 임명구;김수영
    • 한국디지털건축인테리어학회논문집
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    • 제1권1호
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    • pp.51-58
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    • 2001
  • The purpose of this study is to improve productivity of architectural space planning(A.S.P,) by computer system and to optimize ASP. A searching algorithm is the best way to slave optimized A.S.P. Because architectural design is too many various site situations and client's demands to specify the general solving methods. This method seek the best design case in all possibility and to be modeled as this; $\rightarrow$[$\rightarrow$$\rightarrow$