• Korean Journal of Optics and Photonics
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• v.15 no.4
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• pp.349-354
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• 2004

As a transmitter sub-assembly in the XFP(10 Gb/s Small Form Factor Pluggable) transceiver module, a transmitter optical sub-assembly(TOSA) is designed, fabricated and characterized in view of electrical and thermal performances. For a low-cost and compact packaging TOSA, the bias-tee and the matching resistor are monolithically integrated on the AlN sub-mount and a newly designed coplanar waveguide is drawn in the TO-stem. All optoelectronic components packaged in the TOSA are modeled by the equivalent circuit, which helps to improve and characterize the TOSA performance. The fabricated TOSA shows the -3㏈ bandwidth as high as 11 GHz at an elevated temperature of 85$^{\circ}C$.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.32 no.6
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• pp.429-445
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• 2008

Two-phase compressible flow fields of air-water are investigated numerically in the fixed Eulerian grid framework. The phase interface is captured via volume fractions of each phase. A way to model two phase compressible flows as a single phase one is found based on an equivalent equation of states of Tait's type for a multiphase cell. The equivalent single phase field is discretized using the Roe‘s approximate Riemann solver. Two approaches are tried to suppress the pressure oscillation phenomena at the phase interface, a passive advection of volume fraction and a direct pressure relaxation with the compressible form of volume fraction equation. The direct pressure equalizing method suppresses pressure oscillation successfully and generates sharp discontinuities, transmitting and reflecting acoustic waves naturally at the phase interface. In discretizing the compressible form of volume fraction equation, phase interfaces are geometrically reconstructed to minimize the numerical diffusion of volume fraction and relevant variables. The motion of a projectile in a water-filled tube which is fired by the release of highly pressurized air is simulated presuming the flow field as a two dimensional one, and several design factors affecting the projectile movement are investigated.

• IMMUNE NETWORK
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• v.16 no.5
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• pp.305-310
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• 2016

In this study, we compared two different tumor cell vaccines for their induction of anti-tumor immunity; one was a tumor cell clone expressing a membrane-bound form of IL-12 p35 subunit (mbIL-12 p35 tumor clone), and the other was a tumor clone expressing heterodimeric IL-12 as a single chain (mb-scIL-12 tumor clone). The stimulatory effect of mb-scIL-12 on the proliferation of ConA-activated splenocytes was higher than that of mbIL-12 p35 in vitro. However, the stimulatory effect of mbIL-12 p35 was equivalent to that of recombinant soluble IL-12 (3 ng/ml). Interestingly, both tumor clones (mbIL-12 p35 and mb-scIL-12) showed similar tumorigenicity and induction of systemic anti-tumor immunity in vivo, suggesting that tumor cell expression of the membrane-bound p35 subunit is sufficient to induce anti-tumor immunity in our tumor vaccine model.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.18 no.5
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• pp.443-448
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• 2009

The roughness models have developed to describe the grinding behaviour and predict the final quality of workpiece. The model forms of the plunge grinding process are generally established with initial and steady state model form in accordance with the accumulated metal removal. The steady state roughness model form are based on the grinding condition and specific parameters are used to show the influence of it according to the grinding process such as the equivalent chip thickness and accumulated metal removal. However, the models have been developed in past are not considered the effect of changing the grinding conditions in the same batch. In this paper, the roughness model form to consider the effect of changing grinding condition is proposed and the performance of proposed model is evaluated based on the experimental results.

• Journal of Radiation Industry
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• v.10 no.4
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• pp.219-225
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• 2016

The apron is one of the essential protectors to reduce the exposure dose of radiological technologists. This study is to provide a guideline for purchasing the aprons with excellent performance and to help reducing the exposure dose by measuring the shielding ration and uniformity of aprons according to lead equivalent and form types. The shielding ratio of aprons were measured by using radiation generator and dosimeter. Exposure conditions were 81 kVp, 25 mAs, source to image receptor distance (SID) 100 cm and field of view (FOV) $17^{{\prime}{\prime}}{\times}17^{{\prime}{\prime}}$. Exposure areas for front type and around type aprons were divided into 9 areas and for 2 pieces type aprons were divided into 3 areas of top and 4 areas of skirt. The uniformity of aprons were measured by using fluoroscopy and Image J. The 4 regions of interest (ROI) were set into acquired images and measured uniformity by measuring the standard deviation of pixel intensity in ROIs. In continuous shielding ration measurement of aprons according to exposure area, there was not statistical significance (P>0.05). In ANOVA test of aprons, there was statistical significance (P<0.01). In the results of sheilding ratio, although the aprons had equal lead equivalent, there were difference in shielding ratio from 83.59% to 98.15%. In the results of uniformity, the front type aprons with equal lead equivalent indicated the similar uniformity. However, the around type and 2 pieces type apron with equal lead equivalent indicated the different uniformity each other, from 1.8 to 22.2. If the performance evaluation in this study were conducted regularly before and after purchase the aprons, the exposure does to patients and radiological technologists could be reduced.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.1
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• pp.19-28
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• 2018

The time for form removal is an important factor for ensuring the safety and economical efficiency of concrete structures, because it affects the quality, period, and cost of construction. Although local specifications suggest the form curing time, there is a problem of low quality of concrete due to early removing of form. This is because they do not fully understand effect of curing condition, and they want to shorten construction period in the field. Therefore, this research evaluates the effect of curing condition according to the time for form removal by testing specimen. As a result, the concrete compressive strength at the age of 28 days decreased about 40% in the condition of form removal after 12 hours, while the strength in the condition of form removal after 28 days decreased about 7%. Finally, this paper suggests an estimating equation for the concrete compressive strength due to the time for form removal considering various curing temperatures as equivalent ages. The proposed equation can be used in the field for evaluating the strength after form removal.

• BMB Reports
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• v.53 no.9
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• pp.453-457
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• 2020

The right-handed double-helical structure of DNA (B-DNA), which follows the Watson-Crick model, is the canonical form of DNA existing in normal physiological settings. Even though an alternative left-handed structure of DNA (Z-DNA) was discovered in the late 1970s, Z-form nucleic acid has not received much attention from biologists, because it is extremely unstable under physiological conditions, has an ill-defined mechanism of its formation, and has obscure biological functions. The debate about the physiological relevance of Z-DNA was settled only after a class of proteins was found to potentially recognize the Z-form architecture of DNA. Interestingly, these Z-DNA binding proteins can bind not only the left-handed form of DNA but also the equivalent structure of RNA (Z-RNA). The Z-DNA/RNA binding proteins present from viruses to humans function as important regulators of biological processes. In particular, the proteins ADAR1 and ZBP1 are currently being extensively re-evaluated in the field to understand potential roles of the noncanonical Z-conformation of nucleic acids in host immune responses and human disease. Despite a growing body of evidence supporting the biological importance of Z-DNA/RNA, there remain many unanswered principal questions, such as when Z-form nucleic acids arise and how they signal to downstream pathways. Understanding Z-DNA/RNA and the sensors in different pathophysiological conditions will widen our view on the regulation of immune responses and open a new door of opportunity to develop novel types of immunomodulatory therapeutic possibilities.

• Journal of The Korean Society of Agricultural Engineers
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• v.57 no.2
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• pp.47-56
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• 2015

At the present, the mechanized form roads pavement was constructed with plain concrete. Mostly, it was used by welded wire mesh for preventing crack. Cellulose fibers for the reinforcement of concrete offer relatively high levels of elastic modulus, fiber count (per unit weight), specific surface, and bond strength to cement-based materials. The construction of concrete pavement confirmed that cellulose fiber reinforced concrete was applicable to mechanized form roads pavement. In the study, cellulose fibers were used here at 0.08 % volume fraction, which is equivalent to a fiber content of $1.2kg/m^3$. Cellulose fiber reinforced concrete were compared with plain concrete. Field test results indicated that cellulose fiber reinforced concrete showed slightly to increase of 28 days compressive strength and improved the initial strength. it tended to increase of splitting tensile strength. Test results showed that the slump and air content tend to decreased. but, the variation of air contends is very little. Also, construction cost of cellulose fiber reinforced concrete is less than about 25.7 % the case of welded wire mesh previously used. Therefore, The cost reduction is expected to be possible in construction site by mechanized form roads pavement.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.24 no.4
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• pp.457-462
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• 2011

In this study, a simplified design procedure for friction dampers of a multi-story structure in order to reduce seismic response is proposed. To get insight for control effect of the structure with friction dampers is difficult, because of a nonlinear characteristic by a friction damper. Since a control force of a friction damper is influenced by coupling velocity between floors, adjoining modes are coupled. Thus structural response are derived by assuming steady-state response in resonance. As it is impossible that an exact solution is obtained for seismic load, first, a closed form solution can be achieved under harmonic vibration. Second, to convert a three-story building into a single-degree-of-freedom(SDOF) structure, modal analysis is performed. Third, an equivalent damping ratio is derived with utilizing closed form solution. And response reducing factor is proposed by it. Finally, friction force of a damper is designed for using response reducing factor, and then designed dampers are verified for seven seismic data. The nonlinear analysis results confirm the validity of the proposed procedure.

• Proceedings of the KIEE Conference
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• 2006.07a
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• pp.143-144
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• 2006

The recent power systems are very complex and to model them completely is impractical for analysis of electromagnetic transient Therefore areas outside the immediate area of interest must be represented by some form of Frequency Dependent Network Equivalent (FDNE). In this paper a method for developing Frequency Dependent Network Equivalent (FDNE) using S-domain rational Function Fitting is presented and demonstrated. The FDNE is generated by Linearized Least Squares Fitting(LSF) of the frequency response of a S-domain formulation. This Three-port FDNE have been applied to the test AC power system. The electromagnetic transient package PSCAD/EMTDC is used to assess the transient response of the Three-port FDNE developed under different condition. The study results have indicated the robustness and accuracy of Three-port FDNE for analisys of electromagnetic transient and harmonic assessment.