• 약학회지
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• 제37권5호
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• pp.520-526
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• 1993

The purpose of this study is to assess the clinical efficacy and safety of NRM granules which were newly developed as a combination product containing antacids, digestive enzymes and herb drugs for the treatmet of various symptoms of upper gastrointestinal disorders taking SGN granules of similiar but different composition as a control. One hundred and twenty one patients were randomly allocated to receive one pack of either NRM granule(80 cases) or SGN granules(41 cases) three times a day after meal and undergone symptomatic, endoscopic and clinical laboratory assessment before and after two weeks of treatment. The results were as follows; 1. All symptoms except anorexia showed improvements in more than 90% of total cases with each symptom in the NRM group. 2. The general improvement rate was 97.5% in NRM group, and was superior to the(92.5%) of SGN group. 3. Two cases of NRM group and one case of SGN group developed mild nausea, and onecase of SGN group developed mild epigastric soreness. No cases of the two groups developed laboratory(blood, biochemical, urine) abnormalities. 4. The overall clinical efficacy rate was 95.0% in NRM group, 87.8% in SGN group. kccording to the result of this trial, it was concluded that NRM granule was an effective and safe drug and(but not statistically significant) was slightly more efficient than SGN for treatment of various symptoms in upper gastrointestinal disorders.

• 대한세포병리학회지
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• 제10권1호
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• pp.79-84
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• 1999

Osteoclast-like giant cell tumor of the liver is an extremely rare malignancy with poor prognosis. To our knowledge, 5 cases have been reported in English literatures, but there was no report about fine needle aspiration cytologic(FNAC) features. We experienced a case of osteoclast-like giant cell tumor of the liver obtained by computed tomography(CT)-guided FNAC and needle biopsy. The cytologic findings mimicked slant cell tumor of the bone. A large hepatic mass of the left lobe with abdominal wall invasion was found by CT in a 46- year-old female complaining of epigastric pain. The FNAC showed moderately cellular smears consisting of osteoclast-like giant cells and mononuclear cells, which were individually scattered or intermingled in clusters. The osteoclast-like giant cells had abundant cytoplasms and multiple small round nuclei with fine chromatin and distinct nucleoli. The mononuclear cells had moderate amount of cytoplasm and relatively bland-looking oval nuclei with single small nucleoli. All of the cytologic features recapitulated the histologic findings of bland-looking osteoclast-like multinucleated giant cells evenly dispersed throughout the background of mononuclear cell. The immunohistochemical study showed positive reaction for CD68 and vimentin, but negative for cytokeratin in both osteoclast-like slant cells and mononuclear cells.

• Archives of Plastic Surgery
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• 제38권3호
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• pp.241-244
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• 2011

Purpose: Seroma formation is still major complication of abdominal donor site after TRAM flap surgery in spite of various efforts to reduce seroma formation such as closed suction drain. We performed a clinical study, that quilting suture at abdominal donor site can prevent seroma formation. Methods: Between May 2002 and September 2008, we performed 600 breast reconstructions using a unilateral TRAM flap except patients who has smoking history or abdominal scar. We performed 300 breast reconstructions without quilting sutures (A: Experimental group) until January 06, and after then 300 reconstructions with quilting sutures (B: Control group). We compared total drain output (mL), time to drain removal (days), and donor site complications between two groups. Results: There were no statistical difference at BMI (p=0.28) and time to remove suction drain between two group. (A: 8.37, B: 9.69) (p=0.40) But, total drain output was reduced with quilting suture. (A: 432.5, B: 495.2) (p=0.005) And also complication rate was decreased, such as seroma formation, epigastric bulging. (A: 1%, B: 7%) (p=0.005) Conclusion: Quilting suture is a simple and reliable method to reduce seroma formation and abdominal donor site complication.

• 동의신경정신과학회지
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• 제11권1호
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• pp.47-57
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• 2000

This study was designed and performed to identify the effects of oriental medical therapy on hwabyung patients by investigating the life events as the cause of Hwabyung, recent stress perception which influences the clinical appearances and change of symptoms by means of objective scales. 1. Through life events rating scale, life events are reported as follows, in the order of majority. Health, discord within family, martial life, friendship and interest, religion etc. Hwabyung patients experienced negative stress much more than positive stress. 2. Through the GARS (Global Assessment of Recent Stress), there were some significant decreases of stress perception in stress4(stress of sickness or injury), stress7(stress of change or no change in routine) and stress8(overall global stress)(p<0.05, respectively), but there were no significant decreases in five items out of eight items. 3. There were significant decreases of all rated symptoms(feeling of chest oppressed, stuffy in the chest or epigastric mass, feeling of something pushing-up, flushing of body or face, abrupt impulsion of anger, resentment), which were checked weekly for 4 times (p<0.05, respectively). In this study the symptoms of hwabyung were improved regardless of stress perception. It means that hwabyung can be improved significantly with oriental medical therapy.

• Parasites, Hosts and Diseases
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• 제37권3호
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• pp.189-194
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• 1999

A case of human infection with Heterophyes nocens (Heterophyidae) was incidentally found in a biopsy specimen of the Meckel's diverticulum at the upper part of the small intestine. The patient was a 58-year-old man living in a rural area of Talsong-gun, Kyongsangbuk-do.He had gastrointestinal symptoms such as epigastric pain, indigestion, and abdominal discomfort for 3 months, and severe diarrhea, abdominal pain, and vomiting for about 1 month before hospitalization. Endoscopy of the upper part of the small intestine revealed a Meckel's diverticulum, and it was excised and histo-pathologically examined. Three adult flukes were incidentally found sectioned in the mucosa, and they were identified as H.nocens. The patient had a history of eating raw mullets at a fish market in Pusan 6 months ago, and the mullets were presumed to be the source of infection. This case brings a considerable interest in that specific diagnosis of heterophyid infections could be done by sectional morphology of the worms.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제6권2호
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• pp.183-186
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• 2003

저자들은 반복적인 구토와 복통이 발생한 후 토혈을 주소로 내원한 3세 된 남아에서 상부소화관 내시경으로 진단된 위식도 탈출증 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제35권7호
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• pp.553-555
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• 2002

경복부 접근법은 관상동맥우회술후 재수술시 정중 흉골절개에 동반될 수 있는 위험성을 피할 수 있다는 장점 때문에 선택적으로 적용될 수 있는 접근법 중의 하나이다. 관상동맥우회술 후 협심증이 재발한 59세 여자 환자에서 경복부 접근법을 통하여 심폐바이패스를 이용하지 않는 관상동맥우회술을 시행하였다. 검상돌기하 부위 에 경복부 절개술을 시행하고 개복한 후 이식혈관으로 우위 대망동맥을 준비하였으며, 우심실과 횡격막 사이의 유착을 박리한 뒤, 심폐바이패스를 이용하지 않고 심박동하에서 우위대망동맥을 우관상동맥에 문합하였다. 술후 1일째 시행한 관상동맥조영술에서 문합부위에 이상이 없음을 확인하였고, 합병증 없이 술 후 4일째 퇴원하였다. 정중 흉골절개가 아닌 경복부 접근법을 통해 심폐바이패스를 이용하지 않는 관상동맥 우회 재수술을 시행하고 만족할 만한 결과를 얻었기에 이 증례를 보고하는 바이다.

• Journal of Chest Surgery
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• 제27권4호
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• pp.331-334
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• 1994

Pneumatic rupture is a rare cause of esophageal injury, as evidenced by only 19 cases reported in the literature. We experienced one case of esophageal rupture due to bursting of a truck inner tube. The patient, who was a 45-year old male, had severe chest pain, respiratory distress, flushing in the face and neck, and subcutaneous emphysema after tire explosion. Three days after the incident, a diagnosis of rupture of the thoracic esophagus was established by esophagogram using water soluble contrast media, and then emergency operation was done. The operation involved mediastinal and thoracic drainage and resection of the esophagus combined with cervical esophagostomy and feeding gastrostomy. On the 105th day after the operation, cervical esophagogastrostomy via substernal route was performed. The patient was successfully treated with the staged operations. As in the other reported cases, the injury was located in the lower one third of the esophagus. Four main characteristics of the clinical signs of pneumatic rupture are 1] wounds or burns to the face or mouth, 2] chest pain or epigastric pain, 3] subcutaneous emphysema, and 4] respiratory distress. We emphasize that the high index of suspicion of esophageal rupture is very important in diagnosis and that diagnosis should be based on the same findings common to other forms of esophageal injury.

• Journal of Chest Surgery
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• 제51권3호
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• pp.209-212
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• 2018

Superior mesenteric artery (SMA) aneurysms are rare and often fatal. A 72-year-old man had previously been admitted to the emergency room with epigastric pain and heart murmur. The echocardiographic diagnosis was vegetation on the aortic and mitral valves, with moderate regurgitation from both valves due to infective endocarditis. No aneurysm was detected on abdominal computed tomography, and emergency double-valve replacement was performed. On postoperative day 25, the patient experienced abrupt abdominal pain, and computed tomography revealed a mycotic SMA aneurysm. Open surgical repair of the SMA aneurysm was performed using the femoral vein, and the patient's postoperative course was uneventful.

• Clinical and Experimental Pediatrics
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• 제59권sup1호
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• pp.72-75
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• 2016

Eosinophilic gastroenteritis is a rare disease characterized by prominent eosinophilic tissue infiltration of the gastrointestinal tract. Here, we report a case of eosinophilic gastroenteritis in an 18-year-old patient with prolonged nephrotic syndrome who presented with abdominal pain and peripheral hypereosinophilia. During the previous 2 years, he had visited local Emergency Department several times because of epigastric pain and nausea. He had been treated with steroid-dependent nephrotic syndrome since 3 years of age. Tests ruled out allergic and parasitic disease etiologies. Gastroduodenoscopy with biopsy revealed marked eosinophilic infiltration in the duodenum. Renal biopsy findings indicated minimal change disease spectrum without eosinophilic infiltration. The oral deflazacort dosage was increased, and the patient was discharged after abdominal pain resolved. To our knowledge, this is the first report of eosinophilic gastroenteritis in a patient with minimal change disease.