• 전자공학회논문지SC
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• 제45권1호
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• pp.15-24
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• 2008

본 논문은 영상의 블록기반 지역 명암대비 향상을 통한 전역 명암대비 향상 기법을 제안한다. 전역 명암대비 향상 기법은 영상의 특성을 고려하지 않고 히스토그램 평활화만을 통해 명암값의 재분배를 수행함으로써 과도한 밝기값의 화소들을 갖는 결과영상을 유발한다. 반면에 블록기반 지역 명암대비 향상 기법은 블록화 현상 및 이를 줄이는 과정에서 영상의 중요한 특징을 훼손하는 문제점을 갖고 있다. 이런 문제점들을 해결하기 위해 본 논문은 입력영상을 다양한 블록 크기로 분할한 임시영상들에 대해 블록기반 히스토그램 평활화를 수행한다. 그리고 지역 명암대비 향상을 통해 얻어진 전역 히스토그램 평활화 함수를 원 영상에 적용하는 전역 명암대비 향상 기법을 수행한다. 지역 명암대비가 향상된 임시 영상으로부터 전역 히스토그램 평활화 함수를 얻기 때문에 제안하는 방법은 지역 명암대비 향상 기법과 전역 명암대비 향상 기법의 장점들을 갖는다.

• 한국정보통신학회논문지
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• 제15권8호
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• pp.1782-1790
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• 2011

영상처리의 목적은 관측자를 위해서 영상의 시각적인 일면을 증진하는 것이다. 영상증진의 목적은 특정 응용분야에 따라서 달라지며, 또한 특정 목적을 위해서 사용되는 영상 증진 기법들은 다른 응용분야에는 적용되지 못하는 실정이다. 본 논문에서는 먼저 히스토그램 쉬링크 및 평활화, 보수적인 적응적 컨트라스트 증진 필터등에 대해서 살펴 보고져 한다. 그리고 적응적인 컨트라스트 증진 필터 기법을 의료영상에 맞게 구성하는 변수들의 적용값을 최적화했으며, 후 처리로 히스토그램 평활화 기법을 사용했다. 결과적으로 입력치인 의료영상들을 사용하여 적용한 결과 제안한 필터를 적용한 결과치 영상들의 에지가 강조됨을 보였고, 또한 후처리로 인해서 영상외형의 컨트라스트를 향상시켰다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.271-272
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• 1998

Contrast-enhanced CT has an important role in the assessment of liver lesions. However, the optimal protocol to get most effective result is not clear. The main principle for deciding injection protocol is to optimize lesion detectability by rapid scanning when lesion-to-liver contrast is maximum. For this purpose, we developed a physiological model of contrast medium enhancement based on the compartment modeling and pharmacokinetics. Blood supply to liver was modeled in two paths. This dual supply character distinguishes the CT enhancement of liver from that of the other organs. The first path is by hepatic artery and the second is by portal vein. It is assumed that only hepatic artery can supply blood to hepatocellular carcinoma (HCC) compartment. It is known that this causes the difference of contrast enhancement between normal liver tissue and hepatic tumor. By solving differential equations for each compartment simultaneously using computer program Matlab, CT contrast-enhancement curves were simulated. Simulated enhancement curves for aortic, hepatic, portal vein, and HCC compartments were compared with mean enhancement curves from 24 patients exposed to the same protocols as simulation. These enhancement curves were in a good agreement. Furthermore, we simulated lesion-to-liver curves for various injection protocols, and analyzed the effects. These may help to optimize the scanning protocols for good diagnosis.

• 가족자원경영과 정책
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• 제14권2호
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• pp.109-126
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• 2010

This study set out to investigate if work-family conflict and work-family enhancement would have mediating effects on the impact of gender role attitudes of women from double income households on their satisfaction of work and marriage. A structural modelof gender role attitudes was set as the independent variable, work-family conflict and work-family enhancement as the mediating variables, and work satisfaction and marriage satisfaction as the dependent variables. The subjects consisted of 2,713 married women from double income households and information was obtained from the first year data of the Korean Longitudinal Survey of Women and Families (KLoWF) collected by the Korean Women's Development Institute (KWDI). Using SPSS 15.0 software, descriptive statistics were gathered, and frequency and factor analyses were conducted. AMOS 7.0 software was used to analyze both the measurement model and the structural model. The results indicate that work-family conflict and work-family enhancement had partial mediating effects on the impacts of gender role attitudes on work and marriage satisfaction among women from double income households. Notably, work-family enhancement had a greater effect than work-family conflict, which suggests that the elements of work-family enhancement, which are the positive aspects of work on family and family on work, should be promoted. It is, however, also important to make efforts to resolve work-family conflict by increasing the satisfaction level of work and marriage among women from double income households.

• Korean Journal of Radiology
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• 제19권6호
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• pp.1021-1030
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• 2018

Objective: We evaluated the effect of various patient characteristics and time-density curve (TDC)-factors on the test bolus-affected vessel enhancement on coronary computed tomography angiography (CCTA). We also assessed the value of generalized linear regression models (GLMs) for predicting enhancement on CCTA. Materials and Methods: We performed univariate and multivariate regression analysis to evaluate the effect of patient characteristics and to compare contrast enhancement per gram of iodine on test bolus (${\Delta}HUTEST$) and CCTA (${\Delta}HUCCTA$). We developed GLMs to predict ${\Delta}HUCCTA$. GLMs including independent variables were validated with 6-fold cross-validation using the correlation coefficient and Bland-Altman analysis. Results: In multivariate analysis, only total body weight (TBW) and ${\Delta}HUTEST$ maintained their independent predictive value (p < 0.001). In validation analysis, the highest correlation coefficient between ${\Delta}HUCCTA$ and the prediction values was seen in the GLM (r = 0.75), followed by TDC (r = 0.69) and TBW (r = 0.62). The lowest Bland-Altman limit of agreement was observed with GLM-3 (mean difference, $-0.0{\pm}5.1$ Hounsfield units/grams of iodine [HU/gI]; 95% confidence interval [CI], -10.1, 10.1), followed by ${\Delta}HUCCTA$ ($-0.0{\pm}5.9HU/gI$; 95% CI, -11.9, 11.9) and TBW ($1.1{\pm}6.2HU/gI$; 95% CI, -11.2, 13.4). Conclusion: We demonstrated that the patient's TBW and ${\Delta}HUTEST$ significantly affected contrast enhancement on CCTA images and that the combined use of clinical information and test bolus results is useful for predicting aortic enhancement.

• 대기
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• 제32권4호
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• pp.341-351
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• 2022

Recently, interest in the possibility of a washout effect using artificial rain enhancement technology to reduce high-concentration fine dust is growing. Therefore, in this study, the reduction rate of PM₁₀ concentration according to the amount of artificial rain enhancement was calculated during Asian Dust event which occurred over the Korean Peninsula on March 29, 2021 using air quality model [i.e., Community Multiscale Air Quality (CMAQ)] combined with the mesoscale model for artificial rain enhancement (i.e., WRF-MMS). According to WRF-MMS, the washout effect lasted 5 hours, and the maximum precipitation rate was calculated to be 1.5 mm hr^-1. According the CMAQ results, the PM₁₀ reduction rate was up to 22%, and the affected area was calculated to be 6.4 times greater than that of the artificial rain enhancement area. Even if the maximum amount of precipitation per hour is lowered to 0.8 mm hr^-1 (about 50% level), the PM₁₀ reduction rate appears to be up to 16%. In other words, it is believed that this technique can be used as a direct method for reducing high-concentration fine dust even when the artificial rain enhancement effect is weak.

• 방송공학회논문지
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• 제27권6호
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• pp.840-847
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• 2022

심층 신경망(Deep Neural Network) 기반 음성 향상에서 입력 음성의 글로벌 정보와 로컬 정보를 활용하는 것은 모델의 성능과 밀접한 연관성을 갖는다. 최근에는 다중 스케일을 사용하여 입력 데이터의 글로벌 정보와 로컬 정보를 활용하는 중첩 U-Net 구조가 제안되었으며, 이러한 중첩 U-Net은 음성 향상 분야에도 적용되어 매우 우수한 성능을 보였다. 그러나 중첩 U-Net에서 사용되는 단일 skip connection은 중첩된 구조에 알맞게 변형되어야 할 필요성이 있다. 본 논문은 중첩 U-Net 기반 음성 향상 알고리즘의 성능을 최적화하기 위하여 다중 레벨 skip connection(multi-level skip connection, MLS)을 제안하였다. 실험 결과, 제안된 MLS는 기존의 skip connection과 비교하여 다양한 객관적 평가 지표에서 큰 성능 향상을 보이며 이를 통해 MLS가 중첩 U-Net 기반 음성 향상 알고리즘의 성능을 최적화시킬 수 있음을 확인하였다. 또한, 최종 제안 모델은 다른 심층 신경망 기반 음성 향상 모델과 비교하여서도 매우 우수한 성능을 보인다.

• 대한의용생체공학회:의공학회지
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• 제43권4호
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• pp.193-198
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• 2022

Contrast enhanced magnetic resonance imaging using gadolinium-based contrast agent (GBCA) is a very useful in vivo technique to visualize the inner ear pathology including endolymphatic hydrops. Although systemic intravenous (IV) administration can visualize the perilymph space, the visualization was possible by indirect passage of contrast agent through blood-perilymph barrier. All animal experimental procedures were performed under anesthesia with 5% isoflurane. Lipopolysaccharide (LPS) was instilled into the left tympanic cavity through the tympanic membrane using a sterile 27gauge needle to induce hydrops model. Tucker-Davis Technologies system was used to measure Auditory Brainstem Responses (ABRs). For intracerebroven-tricular (ICV) administration, 25 µmol of GADOVIST (Bayer, Berlin, Germany) was used and diluted GADOVIST injection was 10 µl. MR imaging was acquired with a 9.4 Tesla MRI scanner. Transmit-receive volume coil with 40 mm inner diameter and 75 mm out diameter was used. ICV administration well demonstrated the strong enhancement along the cerebrospinal fluid (CSF) microcirculation pathway including CSF fluid in the subarachnoid space and CSF space of the inner ear structures. On the other hand, IV administration showed no contrast enhancement along the CSF microcirculation pathway and showed weak enhancement in the inner ear structures. In case of rat hydrops model, ICV administration showed that the reduced contrast enhancement in the perilymph space of the hydrops induced inner ear compared to the contrast enhancement in the perilymph space of the normal inner ear. New systemic ICV administration method provide contrast enhancement of GBCA in the inner ear through CSF microcirculation pathway.

• Korean Journal of Radiology
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• 제21권5호
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• pp.561-571
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• 2020

Objective: To evaluate the clinical utility of ultrafast dynamic contrast-enhanced (DCE)-MRI compared to conventional DCE-MRI by studying lesion conspicuity and size according to the level of background parenchymal enhancement (BPE). Materials and Methods: This study included 360 women (median age, 54 years; range, 26-82 years) with 361 who had undergone breast MRI, including both ultrafast and conventional DCE-MRI before surgery, between January and December 2017. Conspicuity was evaluated using a five-point score. Size was measured as the single maximal diameter. The Wilcoxon signed-rank test was used to compare median conspicuity score. To identify factors associated with conspicuity, multivariable logistic regression was performed. Absolute agreement between size at MRI and histopathologic examination was assessed using the intraclass correlation coefficient (ICC). Results: The median conspicuity scores were 5 at both scans, but the interquartile ranges were significantly different (5-5 at ultrafast vs. 4-5 at conventional, p < 0.001). Premenopausal status (odds ratio [OR] = 2.2, p = 0.048), non-mass enhancement (OR = 4.1, p = 0.001), moderate to marked BPE (OR = 7.5, p < 0.001), and shorter time to enhancement (OR = 0.9, p = 0.043) were independently associated with better conspicuity at ultrafast scans. Tumor size agreement between MRI and histopathologic examination was similar for both scans (ICC = 0.66 for ultrafast vs. 0.63 for conventional). Conclusion: Ultrafast DCE-MRI could improve lesion conspicuity compared to conventional DCE-MRI, especially in women with premenopausal status, non-mass enhancement, moderate to marked BPE or short time to enhancement.

• Bulletin of the Korean Chemical Society
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• 제23권4호
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• pp.623-625
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• 2002