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A MEASUREMENT OF THE COSMIC MICROWAVE BACKGROUND B-MODE POLARIZATION WITH POLARBEAR

  • ADE, P.A.R.;AKIBA, Y.;ANTHONY, A.E.;ARNOLD, K.;ATLAS, M.;BARRON, D.;BOETTGER, D.;BORRILL, J.;CHAPMAN, S.;CHINONE, Y.;DOBBS, M.;ELLEFLOT, T.;ERRARD, J.;FABBIAN, G.;FENG, C.;FLANIGAN, D.;GILBERT, A.;GRAINGER, W.;HALVERSON, N.W.;HASEGAWA, M.;HATTORI, K.;HAZUMI, M.;HOLZAPFEL, W.L.;HORI, Y.;HOWARD, J.;HYLAND, P.;INOUE, Y.;JAEHNIG, G.C.;JAFFE, A.H.;KEATING, B.;KERMISH, Z.;KESKITALO, R.;KISNER, T.;JEUNE, M. LE;LEE, A.T.;LEITCH, E.M.;LINDER, E.;LUNGU, M.;MATSUDA, F.;MATSUMURA, T.;MENG, X.;MILLER, N.J.;MORII, H.;MOYERMAN, S.;MYERS, M.J.;NAVAROLI, M.;NISHINO, H.;ORLANDO, A.;PAAR, H.;PELOTON, J.;POLETTI, D.;QUEALY, E.;REBEIZ, G.
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.625-628
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    • 2015
  • POLARBEAR is a ground-based experiment located in the Atacama desert of northern Chile. The experiment is designed to measure the Cosmic Microwave Background B-mode polarization at several arcminute resolution. The CMB B-mode polarization on degree angular scales is a unique signature of primordial gravitational waves from cosmic inflation and B-mode signal on sub-degree scales is induced by the gravitational lensing from large-scale structure. Science observations began in early 2012 with an array of 1.274 polarization sensitive antenna-couple Transition Edge Sensor (TES) bolometers at 150 GHz. We published the first CMB-only measurement of the B-mode polarization on sub-degree scales induced by gravitational lensing in December 2013 followed by the first measurement of the B-mode power spectrum on those scales in March 2014. In this proceedings, we review the physics of CMB B-modes and then describe the Polarbear experiment, observations, and recent results.

Preventive Effects of Rosa rugosa Root Extract on Advanced Glycation End product-Induced Endothelial Dysfunction (해당근 추출물의 항산화 활성 및 최종당화산물에 의한 혈관내피세포 기능장애 억제활성)

  • Nam, Mi-Hyun;Lee, Hyun-Sun;Hong, Chung-Oui;Koo, Yoon-Chang;Seo, Mun-Young;Lee, Kwang-Won
    • Korean Journal of Food Science and Technology
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    • v.42 no.2
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    • pp.210-216
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    • 2010
  • Rosa rugosa has traditionally been used as a folk remedy for diabetes. The objective of this study was therefore to demonstrate the inhibition of endothelial dysfunction activities through antioxidants and the anti-glycation of Rosa rugosa roots. Dried roots of Rosa rugosa were boiled in methanol for three hours, evaporated and lyophilized with a freeze-dryer. The methanolic extract of Rosa rugosa roots (RRE) was tested for antioxidant activities by measuring total polyphenol (TP) content, flavonoid content, 1,1-diphenyl-2-picrylhydrazyl free radical-scavenging activity (DPPH) assay, and ferric-reducing antioxidant power (FRAP) assay. The total TP content, flavonoid content, FRAP value, and $DPPHSC_{50}$ are $345.2\;{\mu}g$ gallic acid equivalents/mg dry matter (DM), $128.1\;{\mu}g$ quercetin equivalents/mg DM, 2.2 mM $FeSO_4$/mg DM and $34.2\;{\mu}g$ DM/mL, respectively. Treatment of RRE significantly lowered fluorescent formation due to advanced glycation reaction. In addition, reactive oxygen species (ROS) scavenging assay, monocyte adherent assay and transendothelial electrical resistance (TEER) assay were performed to investigate the possibility that RRE improves endothelial dysfunction-induced diabetic complications. The adhesion of THP-1 to treated HUVEC with RRE ($100\;{\mu}g/mL$; 33% and $500\;{\mu}g/mL$; 75%) was significantly reduced compared to HUVEC stimulated by glyceraldehydes-AGEs (advanced glycation end product). The TEER value ($88\;{\Omega}{\cdot}cm^2$) of stimulated HUVEC by glyceraldehydes-AGEs was reduced compared to non-stimulation ($113\;{\Omega}{\cdot}cm^2$). However, normalization with RRE increased endothelial permeability in a dose-dependent manner ($100\;{\mu}g/mL$; $102\;{\Omega}{\cdot}cm^2$ and $500\;{\mu}g/mL$; $106\;{\Omega}{\cdot}cm^2$). Thus, these results suggest that Rosa rugosa roots could be a novel candidate for the prevention of diabetic complications through antioxidants and inhibition of advanced glycation end product formation.