• Journal of Korean Neurosurgical Society
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• 제64권3호
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• pp.460-468
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• 2021

Objective : Extremely low alanine transaminase (ALT) levels are associated with all-cause mortality in frail elderly individuals; the clinical significance of ALT as a reliable biomarker is now being considered. Predicting mortality with routine tests at the time of diagnosis is important for managing patients after intracranial hemorrhage. We aimed to investigate whether an extremely low ALT level is associated with mortality in the elderly after intracranial hemorrhage. Methods : A retrospective review was performed on 455 patients with intracranial hemorrhage admitted to a university-affiliated tertiary care hospital from February 2014 to May 2019. Multivariate Cox regression analysis was performed for all ages and for each age group to determine whether an extremely low ALT level is an independent predictor of mortality only in the elderly. Results : Overall, 294 patients were enrolled, and the mean age of the subjects was 59.1 years, with 99 (33.8%) aged ≥65 years. The variables associated with all-cause mortality in all subjects were age, C-reactive protein (CRP) levels, hemoglobin (Hb) levels (<11 g/dL), and initial Glasgow coma scale (GCS) scores. In young patients, CRP, low Hb levels, and initial GCS scores were significantly associated with all-cause mortality. However, in the elderly (≥65 years), the variables significantly associated with all-cause mortality were extremely low levels of ALT (<10 U/L) (adjusted hazard ratio, 3.313; 95% confidence interval, 1.232-8.909; p=0.018) and initial GCS scores. Conclusion : Extremely low ALT level (<10 U/L) at the time of diagnosis is a significant risk factor for all-cause mortality in the elderly after intracranial hemorrhage.

• 한국보건간호학회지
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• 제32권2호
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• pp.304-318
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• 2018

Purpose: This study examined the characteristic of the Injury Severity Score (ISS) of Korean geriatric patients with a traumatic injury in a nationally representative sample to determine the optimal cutoff of ISS of mortality according to age. Methods: The subjects were 3,018 non-elderly patients and 1,584 elderly patients with an ISS and Korean Triage and Acuity Scale (KTAS) in 2016 from the data of the Health Insurance Review and Assessment Service. The traumatic characteristics of the elderly and non-elderly were compared by stratifying the ISS. Receiver Operating Characteristic (ROC) curve analysis was used to find the optimal cutoff of ISS of mortality according to age. Results: The elderly were more prone to severe trauma than the non-elderly were. The distribution of KTAS grades was lower, even though the severity of ISS was as high as that of the non-elderly. The optimal cutoff score of the ISS for mortality in the ROC curve was lower in elderly over 65 years than in the other age group. Conclusion: The elderly are more prone to severe trauma and death than non-elderly, even though their ISS is low. Therefore, a strategy to prevent elderly from experiencing serious trauma and managing their geriatric trauma actively is needed.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2831-2834
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• 2014

The aim of this study was to determine the mortality rate and burden of urinary tract cancers among residents of Inner Mongolia. We analyzed mortality data reported by the Death Registry System from 2008 to 2012. The rate of mortality due to urinary tract cancer was 2.04 per 100,000 person-years for the total population, 2.91 for men, and 1.11 for women. Therefore, the mortality rate for men was 2.62-fold the mortality rate for women, constituting a statistically significant difference (p<0.001). Over the period 2008 through 2012, the total potential years of life lost was 1388.1 person-years for men and 777.1 person-years for women, and the average years of life lost were 7.71 years per male decedent and 12.0 years per female decedent. Mortality due to urinary tract cancers is substantially greater among the elderly population. Further, the mortality rate associated with urinary tract cancers is greater for elderly men than it is for elderly women. Therefore, in Inner Mongolia, urinary tract cancers appear to pose a greater mortality risk for men than they do for women.

• Journal of Korean Neurosurgical Society
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• 제62권2호
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• pp.243-255
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• 2019

Objective : Although traumatic brain injury (TBI) occurs in people of all age groups, the elderly population is at a particular risk. The proportion of elderly population in the society is markedly increasing and Korea is one of the most rapidly aging societies. Here, we analyzed the data from 904 patients older over 65 years who were registered in the Korean Neuro-Trauma Data Bank System (KNTDBS). Methods : The Korean Society of Neurotraumatology recorded data from 20 institutions between September 2010 and March 2014. This retrospective study examined the clinical epidemiology, sex difference, outcome epidemiology, sociodemographic variables, and outcomes in the geriatric population related to TBI based on data from the KNTDBS. Results : The study included 540 men and 364 women. The age distributions in the male and female groups were statistically significantly different. The most common cause of trauma was a fall and diagnosis was acute subdural hematoma. The incidence was the highest in men aged 80-84 years and in women aged 75-79 years. The most common time of arrival to hospital after TBI was within 1 hour and 119 rescue team provided first aid earliest to patients with TBI. The mortality rate stratified according to the cause of trauma was significantly different, with mortality rates of 3.77% in fall and 11.65% in traffic accident. The mortality rates according the severity of brain injury, Glasgow Coma Scale score, and treatment were statistically significant. Conclusion : To our knowledge, this study is the first to focus on elderly patients with TBI in Korea and particularly investigate mortality and characteristics related to TBI-related death based on data from the KNTDBS. Although the study has some limitations, our results may be used to obtain useful information to study targeted prevention and more effective treatment options for older TBI patients and establish novel treatment guidelines and health polish for the geriatric population.

• Journal of Preventive Medicine and Public Health
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• 제45권1호
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• pp.21-28
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• 2012

Objectives: The aim of this study was to investigate whether a medium to high degree of total physical activity and indoor physical activity were associated with reduced all-cause and cardiovascular mortality among elderly Korean women. Methods: A prospective cohort study was done to evaluate the association between physical activity and mortality. The cohort was made up of elderly (${\geq}65$ years of age) subjects. Baseline information was collected with a self-administered questionnaire and linked to death certificates retrieved from a database. Cox proportional hazard models were used to estimate the hazard ratios (HRs) with 95% confidence interval (CI) levels. Results: Women who did not suffer from stroke, cancer, or ischemic heart disease were followed for a median of 8 years (n=5079). A total of 1798 all-cause deaths were recorded, of which 607 (33.8%) were due to cardiovascular disease. The group with the highest level of total physical activity and indoor physical activity was significantly associated to a reduced all-cause mortality (HR, 0.60; 95% CI, 0.51 to 0.71 and HR, 0.58; 95% CI, 0.50 to 0.67, respectively) compared to the group with the lowest level of total physical activity and indoor physical activity. Additionally, the group with the highest level of total physical activity and indoor physical activity was significantly associated to a lower cardiovascular disease mortality (HR, 0.53; 95% CI, 0.40 to 0.71 and HR, 0.51; 95% CI, 0.39 to 0.67, respectively) compared to the group with the lowest level of total physical activity and indoor physical activity. Conclusions: Our study showed that regular indoor physical activity among elderly Korean women has healthy benefits.

• Journal of Preventive Medicine and Public Health
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• 제56권3호
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• pp.231-237
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• 2023

Objectives: This study aimed to identify risk factors associated with coronavirus disease 2019 (COVID-19) mortality in pre-elderly and elderly individuals in Jakarta, Indonesia. Methods: We employed a case-control study design, utilizing secondary data from the Epidemiology Surveillance, Immunization Prevention, and Disease Control Sections of the DKI Jakarta Provincial Health Office, collected from December 2020 to January 2021. The study included 188 cases and an equal number of controls. Cases were COVID-19 patients confirmed to have died, as reported by hospitals and communities and subsequently verified by healthcare workers. Control subjects were patients who completed a 14-day isolation period and had been officially declared recovered by healthcare professionals. The dependent variable was the mortality of COVID-19 patients in the January 2021 period. The independent variables consisted of demographic data (age and sex), clinical symptoms (cough, runny nose, anosmia, diarrhea, headaches, abdominal pain, muscle pain, and nausea/vomiting), and comorbidities (hypertension, heart disease, and diabetes). Multivariate analysis was conducted using multiple logistic regression. Results: The multiple logistic regression analysis revealed several factors associated with COVID-19 fatalities in Jakarta: age of 60 years or older (odds ratio [OR], 4.84; 95% CI, 3.00 to 7.80), male (OR, 2.38; 95% CI, 2.41 to 3.68), dyspnea (OR, 3.93; 95% CI, 2.04 to 7.55), anosmia (OR, 0.13; 95% CI, 0.04 to 0.46), and heart disease (OR, 4.38; 95% CI, 1.04 to 18.46). Conclusions: The control and prevention of COVID-19 among elderly individuals require particular vigilance. When a COVID-19 case is detected within this demographic, prompt treatment and medication administration are crucial to mitigate the presenting symptoms.

• 한국산학기술학회논문지
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• 제21권7호
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• pp.616-624
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• 2020

본 연구의 목적은 노인 운수사고 입원 환자의 운수사고 유형과 사망 사이의 연관성을 분석하여, 노인 운수사고 입원 및 사망 환자를 줄이기 위한 운수사고 유형에 따른 체계적이고 효과적인 정책 개발 및 수립에 기여하기 위함이다. 본 연구의 방법은 2013-2017년의 질병관리본부 퇴원손상심층조사 데이터세트 중 운수사고를 입은 노인 입원환자를 추출하여 기술통계분석, 카이제곱검정과 다중 로지스틱 회귀분석을 실시하였다. 인구사회학적, 의료기관, 의료이용 특성을 보정한 상태에서 분석한 결과 운수사고로 인한 노인의 입원 사망은 승용차 사고에 비하여 보행자 사고(OR : 2.522 95% CI 1.291-4.927), 자전거/카트 사고(OR : 2.809 95% CI 1.328-5.942), 오토바이 사고(OR : 2.330 95% CI 1.126-4.819)로 인한 사망이 각각 통계적으로 유의하게 높았다. 이와 같이 노인의 경우 승용차 사고로 인한 사망에 비하여 다른 유형의 운수사고로 인한 사망의 위험이 높지만, 우리나라 노인의 운수사고 관련 정책은 승용차 사고에 집중되어 있다. 따라서 증가하는 노인 집단의 운수사고 사망자를 줄이기 위하여 노인 집단의 운수사고 유형별 특성에 따른 효과적인 정책적 고려가 필요할 것으로 사료된다.

• 한국엔터테인먼트산업학회논문지
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• 제13권6호
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• pp.165-173
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• 2019

본 연구는 노인여성의 사망률 개선을 위한 밴드 서킷 트레이닝의 중재 효과를 구명하여 노인들의 삶의 질 향상을 위한 효과적인 운동 중재 프로그램을 제공하는 데 목적이 있다. 본 연구의 목적을 달성하기 위해서 Y시 소재 만 65세 이상 여성을 대상으로 8주간 밴드 서킷 트레이닝 중재가 노인여성의 밴드 서킷 트레이닝 중재가 노인여성의 Senior Fitness Test(SFT)와 Sitting Rising Test(SRT)에 미치는 영향을 구명하여 다음과 같은 결론을 얻었다. 밴드 서킷 트레이닝 중재에 따른 노인여성의 기능적 체력(의자에 앉았다 일어서기, 2kg 덤벨 들기, 2분 제자리 걷기, 의자에 앉아 앞으로 숙이기, 등 뒤로 손잡기, 2.44m 왕복걷기)와 Sitting Rising Test(SRT)는 측정시기와 집단 간 통계적으로 유의한 상호작용효과가 나타났으며, 실험집단에서 밴드 서킷 트레이닝 중재 후 긍정적으로 개선된 것으로 나타났다. 이상의 연구결과를 종합해 볼 때 밴드 서킷 트레이닝 중재는 노인들의 사망률과 관련이 있는 기능적 체력과 SRT에 긍정적 영향을 미치는 것으로 나타나 노인들의 사망률 개선을 통해서 삶의 질 향상을 위한 효과적인 운동 중재 프로그램으로 적용 가능하다고 생각된다.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제7권7호
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• pp.275-280
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• 2018

세계 인구의 고령화가 진행되는 오늘날 노인들을 위한 의료 서비스의 수요는 점차 증가할 것으로 보인다. 특히, 응급실을 방문하는 노인 환자는 일반 환자보다 다양한 질병을 갖고 있거나, 특이한 증상을 호소하는 등 복잡한 의학적, 사회적 및 신체적 문제를 가지고 있는 경우가 많다. 우리는 65세 이상의 응급실을 방문한 노인 환자의 사망률 예측을 위해 연령, 성별, 혈압, 체온, 혈액검사, 주증상명 등의 의료 데이터를 사용하였다. Feed Forward 신경망과 지지벡터기계를 각각 학습하여 사망률을 예측하고 그 성능을 비교하였다. 1개의 은닉층을 사용한 Feed Forward 신경망의 실험결과가 가장 좋았으며, 이 때 F1 점수는 52.0%, AUC는 88.6%이다. 좀 더 좋은 의료 자질을 추출하여 제안 시스템의 성능을 향상시킨다면 응급실에 방문한 노인 환자들을 위한 효과적이고 신속한 의료 자원 배분을 통해 더 좋은 의료 서비스를 제공할 수 있을 것이다.

• 대한예방한의학회지
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• 제25권3호
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• pp.25-37
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• 2021

Objectives : To investigate the effectiveness of Korean Medicine services use on the all-cause mortality and incidence of Parkinson's disease(PD) in elderly patients with chronic disease based on the National Health Insurance Service Corhort Database (elderly), called as the NHIS-senior. Methods : This study was a retrospective cohort analysis conducted using the NHIS-senior. Patients with chronic diseases over 65 years old who were not diagnosed PD during 2007-2009 were identified. The case group was defined as patients who used both Korean Medicine and Western Medicine services and the control group consisted of patients who used Western Medicine service only. The all-cause mortality and incidence of PD was analyzed using the Cox proportional hazard model after a propensity score matching(PSM) with a 1:1 ratio. Results : After PSM, the cohort included 47,546 subjects (23,773 in the case group, 23,773 in the control group). Sex, age, comorbidity, severity of disability, and neurology medical service utilization were adjusted in both groups. The mortality was 0.668 times (95% C.I.: 0.646-0.690) lower in the case group than the control group, which was statistically significant (p<0.001). The incidence of PD was 1.051 times (95% C.I.: 0.962-1.148) higher in the case group than the control group, which was not statistically significant(p=0.272). Conclusion : It was not obvious that the use of both Korean Medicine service and Western Medicine services for prevention of PD is benefitial than using only Western Medicine. But it would be possible that using both Korean Medicine and Western Medicine services decreases the mortality than using Western Medicine alone.